Worldwide distribution of HFI
alleles
Country |
Alleles |
A149P |
A174D |
N334K |
D4E4 |
R59Op |
L256P |
A337V |
Other |
Unknown |
D.I.a |
References |
America |
275 |
119 |
25 |
5 |
13 |
10 |
4 |
3 |
4 |
92 |
79 |
b |
France |
268 |
179 |
39 |
9 |
1 |
5 |
|
6 |
17 |
12 |
98 |
c |
Germany |
150 |
97 |
16 |
11 |
4 |
2 |
|
|
13 |
7 |
97 |
d |
Italy |
119 |
48 |
27 |
8 |
7 |
|
2 |
|
19 |
8 |
91 |
e |
UK |
60 |
43 |
7 |
6 |
2 |
1 |
|
|
1 |
|
100 |
f |
Poland |
52 |
35 |
3 |
|
1 |
|
|
|
8 |
5 |
93 |
Gruchota et al 2006 |
Spain |
43 |
29 |
4 |
1 |
7 |
|
|
|
2 |
|
96 |
Sanchez-Gutierrez et al 2002 |
Switzerland |
33 |
20 |
10 |
|
|
|
|
|
3 |
|
99 |
g |
Turkey |
16 |
12 |
1 |
1 |
|
|
|
1 |
1 |
|
98 |
h |
Yugoslavia |
14 |
4 |
3 |
7 |
|
|
|
|
|
|
100 |
i |
Austria |
6 |
2 |
|
2 |
|
1 |
|
|
1 |
|
90 |
j |
Norway |
4 |
4 |
|
|
|
|
|
|
|
|
100 |
Larsen et al 1994 |
Israel |
4 |
3 |
|
|
|
|
|
|
1 |
|
94 |
Cox 1994 |
Finland |
2 |
1 |
1 |
|
|
|
|
|
|
|
100 |
Ali et al 1998 |
Middle East |
2 |
1 |
1 |
|
|
|
|
|
|
|
100 |
k |
Australia |
2 |
2 |
|
|
|
|
|
|
|
|
100 |
Wilson et al 1995 |
N. Zealand |
2 |
1 |
|
|
|
|
|
|
1 |
|
75 |
Ali et al 1996 |
Portugal |
2 |
1 |
|
|
|
|
|
|
|
1 |
75 |
Lopes et al 1997 |
India |
2 |
|
|
|
1 |
|
|
|
|
1 |
- |
l |
China |
1 |
|
|
|
1 |
|
|
|
|
|
100 |
Chi et al 2007 |
Japan |
1 |
|
|
|
|
|
|
|
1 |
|
- |
Kajihara et al 1990 |
Totals |
1058 |
601 |
137 |
50 |
37 |
19 |
6 |
10 |
72 |
126 |
|
|
Frequency |
|
0.57 |
0.13 |
0.05 |
0.03 |
0.02 |
0.01 |
0.01 |
0.07 |
0.12 |
94 |
|
aDiagnostic index
calculated for three alleles (A149P, A174D, N334K) and expressed as a
percentage; bThis study, Kaiser and Hegele 1991; Ali and Cox
1995; cCross and Cox 1990; Cross et al
1990a; Ali et al 1994b; Cox 1994; Costa et al 1998; Davit-Spraul et al 2008; dHillebrand et al 2000; Santer et al
2005; eCross et al 1990a; Sebastio et al
1991; Ali et al 1993; Santamaria et al 1993; Ali et al 1994a; Santamaria et
al 1996; Santamaria et al 1999; Esposito et al 2004; Caciotti et al 2008; fCross et al 1988; Cox 1990; Cross
et al 1990a; Dazzo and Tolan 1990; de Souza et al 1990; Cox 1994; Ali et al
1998; Kullberg-Lindh et al 2002; Kriegshauser et al 2007; gCross and Cox 1990; Cross et al
1990a; Ali et al 1998; hAli et al 1994b; Rellos et al 1999;
Dursun et al 2001; Karabulut et al 2006; iCross et al 1990a; Cross et al
1990b; jCross and Cox 1990; Ali et al
1994b; Cox 1994; kKullberg-Lindh et al 2002; Santer
et al 2005; lD. Tolan, unpublished
data. |