References – E
Ea CK, Deng L, Xia ZP, Pineda G and Chen ZJ (2006) Activation of IKK by TNFa requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO> Molecular Cell in press
Ea CK, Sun L, Inoue JI and Chen ZJ (2004) TIFA activates IkB kinase (IKK) by promoting oligomerization and ubiquitination of TRAF6. Proceedings of the National Academy of Sciences 101 15318-15323
Ear T, Cloutier A and McDonald PP (2005) Constitutive nuclear expression of the IkB kinase complex and its activation in human neutrophils. Journal of Immunology 175 1834-1842
Ear T and McDonald PP (2008) Cytokine generation, promoter activation, and oxidant-independent NF-kB activation in a transfectable human neutrophilic cellular model. BMC Immunology 9 14
Eaves-Pyles T, Szabo C and Salzman AL (1999) Bacterial invasion is not required for activation of NF-kB in enterocytes. Infection and Immunity 67 800-804
Ebadi M, Sharma SK, Wanpen S and Amornpan A (2004) Coenzyme Q(10) inhibits mitochondrial complex-1 down-regulation and nuclear factor-kappa B activation. Journal of Cellular and Molecular Medicine 8 213-222
Eberhardt W, Huwiler A, Beck KF, Walpen S and Pfeilschifter J (2000) Amplification of IL-1 beta-induced matrix metalloproteinase-9 expression by superoxide in rat glomerular mesangial cells is mediated by increased activities of NF-kB and activating protein-1 and involves activation of the mitogen-activated protein kinase pathways. Journal of Immunology 165 5788-5797
Eberhardt W, Kilz T, Akool ES, Muller R and Pfeilschifter J (2005) Dissociated glucocorticoids equipotently inhibit cytokine- and cAMP-induced matrix degrading proteases in rat mesangial cells. Biochemical Pharmacology 70 433-445
Eberhardt W, Schulze M, Engels C, Klasmeier E and Pfeilschifter J (2002) Glucocorticoid-mediated suppression of cytokine-induced matrix metalloproteinase-9 expression in rat mesangial cells: involvement of nuclear factor-kB and Ets transcription factors. Molecular Endocrinology 16 1752-1766
Eberle J, Fecker LF, Forschner T, Ulrich C, Rowert-Huber J and Stockfleth E (2007) Apoptosis pathways as promising targets for skin cancer therapy. BritishJournal of Dermatology 156 18-24
Eberle J, Kurbanov BM, Hossine AM, Trefzer U and Fecker LF (2007) Overcoming apoptosis deficiency of melanoma – Hope for new therapeutic approaches. Drug Resistance Update in press
Ebersberger A, Buchmann M, Ritzeler O, Michaelis M and Schaible HG (2006) The role of spinal nuclear factor kappaB ins pinal hyperexcitability. Neuroreport 17 1615-1618
Ebert R, Jovanovic M, Ulmer M, Schneider D, Meissner-Weigl J, Adamski J and Jakob F (2004) Downregulation by nuclear factor kB of human 25-hydroxyvitamin D3 1{alpha}-hydroxylase promoter. Molecular Endocrinology 18 2440-2450
Ebner K, Bandion A, Binder BR, De Martin R and Schmid JA (2003) GMCSF activates NF-kB via direct interaction of the GMCSF-receptor with IkB kinaseb. Blood 102 192-199
Ebnet K, Brown K, Siebenlist U and Shaw S (1997) Borrelia burgdoferi activates NF-kB and is a potent inducer of chemokine and adhesion molecule gene expression in endothelial cells and fibroblasts. Journal of Immunology 158 3285-3292
Eck SL, Perkins ND, Carr DP and Nabel GJ (1993) Inhibition of phorbol ester-induced cellular adhesion by competitive binding of NF-kB in vivo. Molecular and Cellular Biology 13 6530-6536
Eckmann L, Smith JR, Housley MP, Dwinell MB and Kagnoff MF (2000) Analysis by high density cDNA arrays of altered gene expression in human intestinal epithelial cells in response to infection with the invasive enteric bacteria Salmonella. Journal of Biological Chemistry 275 14084-14094
Eddelston J, Herschbach J, Wagelie-Steffen AL, Christiansen SC and Zuraw BL (2007) The anti-inflammatory effect of glucocorticoids is mediated by glucocorticoid-induced leucine zipper in epithelial cells. Journal of Allergy andClinical Immunology 119 115-122
Edderkaoui M, Odinokova I, Ohno I, Gukovsky I, Go VL, Pandol SJ and Gukovskaya AS (2008) Ellagic acid induces apoptosis through inhibition of nuclear factor kappa B in pancreatic cancer cells. World Journal of Gastroenterology 14 3672-3680
Eddins MJ, Carlile CM, Gomez KM, Pickart CM and Wolberger C (2006) Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation. Nature Structural and Molecular Biology in press
Eddy SF, Guo S, Demicco EG, Romieu-Mourez R, Landesman-Bollag E, Seldin DC and Sonenshein GE (2005) Inducible IkB kinase/IkB kinase epsilon expression is induced by CK2 and promotes aberrant nuclear factor-kB activation in breast cancer cells. Cancer Research 65 11375-11383
Eddy SF, McNally JD and Storey KB (2005) Up-regulation of a thioredoxin peroxidase-like protein, proliferation-associated gene, in hibernating bats. Archives of Biochemistry and Biophysics 435 103-111
Edelblum KL, Washington MK, Koyama T, Robine S, Baccarini M and Polk DB (2008) Raf protects against colitis by promoting mouse colon epithelial cell survival through NF-kB. Gastroenterology in press
Edelmann J, Klein-Hitpass L, Carpinteiro A, Fuhrer A, Sellmann L, Stilgenbauer S, Duhrsen U and Durig J (2008) Bone marrow fibroblasts induce expression of PI3K/NF-kB pathway genes and a pro-angiogenic phenotype in CLL cells. Leukemia Research in press
Edelstein LC, Lagos L, Simmons M, Tirumalai H and Gelinas C (2003) NF-kB-dependent assembly of an enhanceosome-like complex on the promoter region of apoptosis inhibitor Bfl-1/A1. Molecular and Cellular Biology 23 2749-2761
Edelstein LC, Pan A and Collins T (2005) Chromatin modifications and the endothelial-specific activation of the E-selectin gene. Journal of Biological Chemistry 280 11192-11202
Edenberg HJ, Xuei X, Wetherill LF, Bierut L, BUcholz K, Dick DM, Hesselbrock V, Kuperman S, Porjesz B, Schuckit MA< Tischfield JA, Almasy LA, Nurnberger Jr JI and Foroud T (2007) Association of NFKB1, which encodes a subunit of the transcription factor NF-kB, with alcohol dependence. Human Molecular Genetics in press
Ediger TL, Schulte NA, Murphy TJ and Toews ML (2003) Transcription factor activation and mitogenic synergism in airway smooth muscle cells. European Respiratory Journal 21 759-769
Edmead C, Kanthou C and Benzakour O (1999) Thrombin activates transcription factors sp1, NF-kB, and CREB: importance of the use of phosphatase inhibitors during nuclear protein extraction for the assessment of transcription factor DNA-binding activities. Analytical Biochemistry 275 180-186
Edwards DN, Towb P and Wasserman SA (1997) An activity-dependent network of interactions links the Rel protein Dorsal with its cytoplasmic regulators. Development 124 3855-3864
Edwards MR, Haas J Panettieri Jr RA, Johnson M and Johnston SL (2007) Corticosteroids and beta 2 agonists differentially regulate rhinovirus induced IL-6 via distinct cis-acting elements. Journal of Biological Chemistry in press
Edwards MR, Hewson CA, Laza-Stanca V, Lau HT, Mukaida N, Hershenson MB and Johnston SL (2007) Protein kinase R, IkB kinase-b and NF-kB are required for human rhinovirus induced pro-inflammatory cytokine production in bronchial epithelial cells. Molecular Immunology 44 1587-1597
Edwards MR, Kebadze T, Johnson MW and Johnston SL (2006) New treatment regimes for virus-induced exacerbations of asthma. Pulmonary Pharmacology 19 320-334
Edwards MR, Mukaida N, Johnson M and Johnston SL (2005) IL-1beta induces IL-8 in bronchial cells via NF-kB and NF-IL6 transcription factors and can be suppressed by glucocorticoids. Pulmonary Pharmacology and Therapy 18 337-345
Edwards PD and Moldawer LL (1998) Role of cytokines in the metabolic response to stress. Current Opinion in Clinical Nutrition and Metabolic Care 1 187-190
Eeva J, Ropponen A, Nuutinen U, Eeva ST, Matto M, Eray M and Pelkonen J (2007) The CD40-induced protection against CD95-mediated apoptosis is associated with a rapid upregulation of anti-apoptotic c-FLIP. Molecular Immunology 44 1230-1237
Efferth T (2007) Willmar Schwabe Award 2006: antiplasmodial and antitumor activity of Artemisinin – from bench to bedside. Planta Medica in press
Efferth T, Marschall M, Wang X, Huong SM, Hauber I, Olbrich A, Kronschnabl M, Stamminger T and Huang ES (2002) Antiviral activity of artesunate towards wild-type, recombinant, and ganciclovir-resistant human cytomegaloviruses. Journal of Molecular Medicine 80 233-242
Efimova E, Martinez O, Lokshin A, Arima T and Prabhakar BS (2003) IG20, a MADD splice variant, increases cell susceptibility to gamma-irradiation and induces soluble mediators that suppress tumor cell growth. Cancer Research 63 8768-8776
Efimova EV, Al-Zoubi AM, Martinez O, Kaithamana S, Lu S, Arima T and Prabhakar BS (2004) IG20, in contrast to DENN-SV, (MADD splice variants) suppresses tumor cell survival, and enhances their susceptibility to apoptosis and cancer drugs. Oncogene 23 1076-1087
Efklidou S, Bailey R, Field N, Nousadeghi M and COllins MK (2008) vFLIP from KSHV inhibits anoikis of primary endothelial cells. Journal of Cell Science in press
Efsen E, Bonacchi A, Pastacaldi S, Valente AJ, Wenzel UO, Tosti-Guerra C, Pinzani M, Laffi G, Abboud HE, Gentilini P and Marra F (2001) Agonist-specific regulation of monocyte chemoattractant protein-1 expression by cyclooxygenase metabolites in hepatic stellate cells. Hepatology 33 713-721
Egan LJ, De Lecea A, Lehrman ED, Myhre GM, Eckmann L and Kagnoff MF (2003) Nuclear Factor kB activation promotes restitution of wounded intestinal epithelial monolayers. Am J Physiol Cell Physiol 285 C1028-C1035
Egan LJ, Eckmann L, Greten FR, Chae S, Li ZW, Myhre GM, Robine S, Karin M and Kagnoff MF (2004) IkB-kinaseb-dependent NF-kB activation provides radioprotection to the intestinal epithelium. Proceedings of the National Academy of Sciences USA 101 2452-2457
Egan LJ and Sandborn WJ (1998) Inhibition of nuclear factor kB by sulfasalazine: a new target for inflammatory bowel disease therapy? Gastroenterology 115 1295-1296
Egan LJ, Mays DC, Huntoon CJ, Bell MP, Pike MG, Sandborn WJ, Lipsky JJ and McKean DJ (1999) Inhibition of interleukin-1-stimulated NF-kB RelA/p65 phosphorylation by mesalamine is accompanied by decreased transcriptional activity. Journal of Biological Chemistry 274 26448-26453
Egan LJ and Toruner M (2006) NF-kB signaling: pros and cons of altering NF-kB as a therapeutic approach. Annals of the New York Academy of Sciences 1072 114-122
Egashira K, Suzuki JI, Ito H, AOki M, Isobe M and Morishita R (2008) Long-term follow up of initial clinical cases with NF-kB decoy oligodeoxynucleotide transfection at the site of coronary stenting. Journal of Gene Medicine in press
Egawa T, Albrecht B, Favier B, Sunshine MJ, Mirchandani K, O’Brien W, Thome M and Littman DR (2003) Requirement for CARMA1 in antigen receptor-induced NF-kB activation and lymphocyte proliferation. Current Biology 13 1252-1258
Egberts JH, Patzold BS, Kettler B, Tepel J, Kalthoff H and Trauzold A (2008) Dexamethasone reduces tumor recurrence and metastasis after pancreatic tumor resection in SCID mice. Cancer Biology and Therapy 7 in press
Eggert M, Goertsches R, Seeck U, Dilk S, Neeck G and Zettle UK (2007) Changes in the activation level of NF-kB in lymphocytes of MS patients during glucocorticoid pulse therapy. Journal of the Neurological Sciences in press
Eggert M, Schulz M and Neeck G (2001) Molecular mechanisms of glucocorticoid action in rheumatic autoimmune diseases. Journal of Steroid Biochemistry and Molecular Biology 77 185-191
Eggert M, Seeck U, Semmler M, Maass U, Dietmann S, Schulz M, Dotzlaw H and Neeck G (2007) An evaluation of anti-TNF-a-therapy in patients with ankylosing spondylitis: imbalanced activation of NF kappaB subunits in lymphocytes and modulation of serum cortisol concentration. Rheumatology International in press
Egorina EM, Sovershaev MA, Kondratiev TV, Olsen JO, Tveita T and Osterud B (2006) Induction of monocytic tissue factor expression after rewarming from hypothermia in vivo is counteracted by heat shock in c-Jun-dependent manner.Arteriosclerosis, Thrombosis and Vascular Biology 26 2401-2406
Ehlers RA, Hernandez A, Bloemendal LS, Ethridge RT, Farrow B and Evers BM (1999) Mitochondrial DNA damage and altered membrane potential (delta psi) in pancreatic acinar cells induced by reactive oxygen species. Surgery 126 148-155
Ehrenreich M, Tarlow MM, Godlewska-Janusz E and Schwartz RA (2007) Incontinentia pigmenti (Bloch-Sulzberger syndrome): a systemic disorder. Cutis 79 355-362
Ehrhardt C, Kardinal C, Wurzer WJ, Wolff T, Von Eichel-Streiber C, Pleschka S, Planz O and Ludwig S (2004) Rac1 and PAK1 are upstream of IKK- and TBK-1 in the viral activation of interferon regulatory factor-3. FEBS Letters 567 230-238
Ehrhardt GR, Hijikata A, Kitamura H, Ohara O, Wang JY and Cooper MD (2008) Discriminating gene expression profiles of memory B cell subpopulations. Journal of Experimental Medicine in press
Ehrhardt H, Fulda S, Schmid I, Hiscott J, Debatin KM and Jeremias I (2003) TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kB. Oncogene 22 3842-3852
Ehrlich LC, Hu S, Peterson PK and Chao CC (1998) IL-10 down-regulates human microglial IL-8 by inhibition of NF-kB activation. Neuroreport 9 1723-1726
Ehrlich M, Sanchez C, Shao C, Hishiyama R, Kehrl J, Kuick R, Kubota T and Hanash SM (2008) ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation. Autoimmunity 41 253-271
Ehrnsperger A, Rehli M, Thu-Hang P and Kreutz M (2005) Epigenetic regulation of the dendritic cell-marker gene ADAM19. Biochemical and Biophysical Research Communications 332 456-464
Eicher DM, Tan T-H, Rice NR, O’Shea JJ and Kennedy ICS (1994) Expression of v-src in T cells correleates with nuclear expression of NF-kB. Journal of Immunology 152 2710-2719
Eichholtz-Wirth H and Sagan D (2002) Altered signaling of TNFalpha-TNFR1 and SODD/BAG4 is responsible for radioresistance in human HT-R15 cells. Anticancer Research 22 235-240
Eichten A, Rud DS, Grace M, Piboonniyom SO, Zacny V and Munger K (2004) Molecular pathways executing the “trophic sentinel” response in HPV-16 E7-expressing normal human diploid fibroblasts upon growth factor deprivation. Virology 319 81-93
Eickelberg O, Roth M, Mussmann R, Rudiger JJ, Tamm M, Perruchoud AP and Block LH (1999) Calcium channel blockers activate the interleukin-6 gene via the transcription factors NF-IL6 and NF-kB in primary human vascular smooth muscle cells [see comments]. Circulation 99 2276-2282
Eickhoff JE and Cotten M (2005) NF-kB activation can mediate inhibition of human cytomegalovirus replication. Journal of Virology 86 285-295
Eickhoff JE, Hanke M, Stein-Gerlach M, Tan PK, Herzberger K, Habenberger P, Muller S, Klebl B, Marschall M, Stamminger T and Cotten M (2004) RICK activates an NF-kB dependent anti-HCMV response. Journal of Biological Chemistry 279 9642-9652
Eisele G, Schwedhelm E, Schieffer B, Tsikas D and Boger RH (2004) Acetylsalicylic acid inhibits monocyte adhesion to endothelial cells by an antioxidative mechanism. Journal of Cardiovascular Pharmacology 43 514-521
Eisenhut M (2006) Effects of HSP70.1/3 gene knockout on NF-kB mediated and cytokine induced reduction in alveolar ion and fluid transport. American Journal of Physiology: Lung Cellular and Molecular Physiology in press
Eisner V, Criollo A, Quiroga C, Olea-Azar C, Santibanez JF, Troncoso R, Chiong M, Diaz-Araya G, Foncea R and Lavandero S (2006) Hyperosmotic stress-dependent NFkB activation is regulated by reactive oxygen species and IGF-1 in cultured cardiomyocytes. FEBS Letters 580 4495-4500
Eisner V, Quiroga C, Criollo A, Eltit JM, Chiong M, Parra V, Hidalgo K, Toro B, Diaz0Araya G and Lavandero S (2006) Hyperosmotic stress activates p65/RelB NFkB in cultured cardiomyocytes with dichotomic actions on caspase activation and cell death. FEBS Letters 580 3469-3476
Eizirik DL, Kutlu B, Rasschaert J, Darville M and Cardozo AK (2003) Use of microarray analysis to unveil transcription factor and gene networks contributing to beta cell dysfunction and apoptosis. Annals of the New York Academy of Sciences 1005 55-74
Eizirik DL, Moore F, Flamez D and Ortis F (2008) Use of a systems biology approach to understand pancreatic beta-cell death in Type 1 diabetes. Biochemical Society Transactions 36 321-327
Ejima K, Layne MD, Carvajal IM, Kritek PA, Baron RM, Chen YH, Vom Saal J, Levy BD, Yet SF and Perrella MA (2003) Cyclooxygenase-2 deficient mice are resistant to endotoxin-induced inflammation and death. FASEB Journal 17 1325-1327
Ejima K and Perrella MA (2004) Alteration in heme oxygenase-1 and nitric oxide synthase-2 gene expression during endotoxemia in cyclooxygenase-2-deficient mice. Antioxid Redox Signal 6 850-857
Ekstrand-Hammarstrom B, Osterlund C, Lilliehook B and Bucht A (2007) Vitamin E down-modulates mitogen-activated protein kinases, nuclear factor-kB and inflammatory responses in lung epithelial cells. Clinical and Experimental Immunology 147 359-369
El Bakkouri K, Wullaert A, Haegman M, Heyninck K and Beyaert R (2005) Adenoviral gene transfer of the NF-kappa B inhibitory protein ABIN-1 decreases allergic airway inflammation in a murine asthma model. Journal of Biological Chemistry 280 17938-17944
El Bekay R, Alvarez M, Alba G, Chacon P, Vega A, Martin-Nieto J, Jimenez J, Monteseirin J, Pintado E, Bedoya FJ and Sobrino F (2003) Oxidative stress is a critical mediator of the angiotensin II signal in human neutrophils: involvement of map kinases, calcineurin, and the transcription factor NF-kB. Blood 102 662-671
El Gazzar M, Yoza BK, Hu JY, COusart SL and McCall CE (2007) Epigenetic silencing of TNFalpha during endotoxin tolerance.
Journal of Biological Chemistry in press
El Gazzar MA, El Mezayen R, Nicolls MR and Dreskin SC (2007) Thymoquinone attenuates proinflammatory responses in lipopolysaccharide-activated mast cells by modulating NF-kB nuclear transactivation. Biochimica et Biophysica Acta in press
El Ghouzzi V, Le Merrer M, Perrin-Schmitt F, Lajeunie E, Benit P, Renier D, Bourgeois P, Bolcato-Bellemin A-L, Munnich A and Bonaventure J (1997) Mutations of the TWIST gene in the Saethre-Chotzen syndrome. Nature Genetics 15 42-46
El Jamali A, Freund C, Rechner C, Scheidereit C, Dietz R and Bergmann MW (2004) Reoxygenation after severe hypoxia induces cardiomyocyte hypertrophy in vitro: activation of CREB downstream of GSK3beta. FASEB Journal 18 1096-1098
El Kasmi KC, Smith AM, Williams L, Neale G, Panopolous A, Watowich SS, Hacker H, Foxwell BM and Murray PJ (2007) A transcriptional repressor and corepressor induced by the STAT3-regulated anti-inflammatory signaling pathway. Journal of Immunology 179 7215-7219
El Kharroubi A, Piras G, Zensen R and Martin MA (1998) Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter. Molecular and Cellular Biology 18 2535-2544
El-Mahmoudy A, Shimizu Y, Shiina T, Matsuyama H, El-Sayed M and Takewaki T (2005) Successful abrogation by thymoquinone against induction of diabetes mellitus with streptozotocin via nitric oxide inhibitory mechanism. International Immunopharmacology 5 195-207
El Mjiyad N, Bontems S, Gloire G, Horion J, Vandevenne P, Dejardin E, PIette J and Sadzot-Delvaux C (2007) Varicella-Zoster Virus modulates NF-kB recruitment on selected cellular promoters. Journal of Virology 81 13092-13104
El-Rayes BF, Ali S, Sarkar FH and Philip PA (2004) Cyclooxygenase-2-dependent and -independent effects of celecoxib in pancreatic cancer cell lines. Molecular Cancer Therapy 3 1421-1426
El-Rayes BF, Anathy V, Ranjan P, Heintz NH and Janssen-Heininger YM (2006)Potentiation of the effect of erlotinib by genistein in pancreatic cancer: the role of Akt and nuclear factor-kB. Cancer Research 66 10553-10559
El Sayah M, Medeiros R, Fernandes ES, Campos MM and Calixto JB (2006) Mechanisms underlying LPS-induced kinin B1 receptor up-regulation in the pig iris sphincter in vitro. Molecular Pharmacology 69 1701-1708
El Shikh ME, El Sayed RM, Wu Y, Szakal AK and Tew JG (2007) TLR4 on follicular dendritic cells: an activation pathway that promotes accessory activity. Journal of Immunology 179 4444-4450
El Yazidi-Belkoura I, Adriaenssens E, Dolle L, Descamps S and Hondermarck H (2003) Tumor necrosis factor receptor-associated death domain protein (TRADD) is involved in the neurotrophin receptor (p75NTR)-mediated anti-apoptotic activity of nerve growth factor in breast cancer cells. Journal of Biological Chemistry 278 16952-16956
El-Zaatari M, Tobias A, Grabowska AM, Kumari R, Scotting PJ, Kaye P, Atherton J, Clarke PA, Powe DG and Watson SZ (2007) De-regulation of the sonic hedgehog pathway in the InsGas mouse model of gastric carcinogenesis. British Journal ofCancer in press
Elcheva I, Tarapore RS, Bhatia N and Spiegelman VS (2008) Overexpression of mRNA-binding protein CRD-BP in malignant melanomas. Oncogene in press
Elco CP, Guenther JM, Williams BR and Sen GC (2005) Analysis of genes induced by Sendai virus infection of mutant cell lines reveals essential roles of interferon regulatory factor 3, NF-kB, and interferon but not Toll-like receptor 3. Journal of Virology 79 3920-3929
Eldor R, Yeffet A, Baum K, Doviner V, Amar D, Ben-Neriah Y, Christofori G, Peled A, Carel JC, Boitard C, Klein T, Serup P, Eizirik DL and Melloul D (2006) Conditional and specific NF-kB blockade protects pancreatic beta cells from diabetogenic agents. Proceedings of the National Academy of Sciences USA 103 5072-5077
Elewaut D, DiDonato JA, Kim JM, Truong F, Eckmann L and Kagnoff MF (1999) NF-kB is a central regulator of the intestinal epithelial cell innate immune response induced by infection with enteroinvasive bacteria. Journal of Immunology 163 1457-1466
Elewaut D, Shaikh RB, Hammond KJ, De Winter H, Leishman AJ, Sidobre S, Turovskaya O, Prigozy TI, Ma L, Banks TA, Lo D, Ware CF, Cheroutre H and Kronenberg M (2003) NIK-dependent RelB activation defines a unique signaling pathway for the development of V{alpha}14i NKT cells. Journal of Experimental Medicine 197 1623-1633
Eley HL, McDonald PS, Russell ST and Tisdale MJ (2008) Inhibition of activation of dsRNA-dependent protein kinase and tumour growth inhibition. Cancer Chemotherapy and Pharmacology in press
Eley HL, Russell ST and Tisdale MJ (2007) Attenuation of muscle atrophy in a murine model of cachexia by inhibition of the dsRNA-dependent protein kinase.British Journal of Cancer 96 1216-1222
Eley HL and Tisdale MJ (2007) Skeletal muscle atrophy: a link between depression of protein synthesis and increase in degradation. Journal of BiologicalChemistry 282 7087-7097
Elgavish A (2000) NF-kB activation mediates the response of a subpopulation of basal uroepithelial cells to a cell wall component of Enterococcus faecalis.Journal of Cell Physiology 182 232-238
El-Guendy N and Rangnekar VM (2003) Apoptosis by Par-4 in cancer and neurodegenerative diseases. Experimental Cell Research 283 51-66
Elguendy N and Sinai AP (2008) Potential problems inherent in cell-based stable NF-kB-GFP reporter systems. Molecular and Cellular Biochemistry in press
El-Guendy N, Zhao Y, Gurumurthy S, Burikhanov R and Rangnekar VM (2003) Identification of a unique core domain of par-4 sufficient for selective apoptosis induction in cancer cells. Molecular and Cellular Biology 23 5516-5525
Eliasson AH and Lettieri CJ (2006) Measuring nuclear factor-KB-who cares? Sleep & Breathing 10 4-5
Eliasson M, Frick IM, COllin M, Sorenson OE, Bjorck L and Egesten A (2007) M1 protein of Streptococcus pyogenes increases production of the antibacterial CXC chemokine MIG/CXCL9 in pharyngeal epithelial cells. Microbial Pathogenesis in press
Eligini S, Banfi C, Brambilla M, Camera M, Barbieri SS, Poma F, Tremoli E and Colli S (2002) 15-Deoxy-delta(12,14)-prostaglandin J(2) inhibits tissue factor expression in human macrophages and endothelial cells: evidence for ERK1/2 signaling pathway blockade. Thrombosis and Haemostosis 88 524-532
Eligini S, Brambilla M, Banfi C, Camera M, Sironi L, Barbieri SS, Auwerx J, Tremoli E and Colli S (2002) Oxidized phospholipids inhibit cyclooxygenase-2 in human macrophages via nuclear factor-kB/IkB- and ERK2-dependent mechanisms. Cardiovascular Research 55 406-415
Eliopoulos AG, Das S and Tsichlis PN (2006) The tyrosine kinase SYK regulates TPL2 activation signals. Journal of Biological Chemistry 281 1371-1380
Eliopoulos AG, Wang CC, Dumitru CD and Tsichlis PN (2003) Tpl2 transduces CD40 and TNF signals that activate ERK and regulates IgE induction by CD40. EMBO Journal 22 3855-3864
Eliopoulos AG and Young LS (1998) Activation of the cJun N-terminal kinase (JNK) pathway by the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1). Oncogene 16 1731-1742
Eliopoulos AG, Blake SM, Floettmann JE, Rowe M and Young LS (1999) Epstein-Barr virus-encoded latent membrane protein 1 activates the JNK pathway through its extreme C terminus via a mechanism involving TRADD and TRAF2. Journal of Virology 73 1023-1035
Eliopoulos AG, Caamano JH, Flavell J, Reynolds GM, Murray PG, Poyet JL and Young LS (2003) Epstein-Barr virus-encoded latent infection membrane protein 1 regulates the processing of p100 NF-kB2 to p52 via an IKKg/NEMO-independent signalling pathway. Oncogene 22 7557-7569
Eliopoulos AG, Davies C, Blake SSM, Murray P, Najafipour S, Tsichlis PN and Young LS (2002) The oncogenic protein kinase Tpl-2/Cot contributes to Epstein-Barr Virus-encoded Latent Infection Membrane Protein 1-induced NF-kB signaling downstream of TRAF2. Journal of Virology 76 4567-4579
Eliopoulos AG, Stack M, Dawson CW, Kaye KM, Hodgkin L, Sihota S, Rowe M and Young LS (1997) Epstein-barr virus-encoded LMP1 and the CD40 receptor mediate IL-6 production in epithelial cells via an NF-kB pathway involving TNF receptor-associated factors. Oncogene 14 2899-2916
Eliopoulos AG, Waites ER, Blake SM, Davies C, Murray P and Young LS (2003) TRAF1 is a critical regulator of JNK signaling by the TRAF-binding domain of the Epstein-Barr virus-encoded latent infection membrane protein 1 but not CD40. Journal of Virology 77 1316-1328
Eliseev RA, VanWinkle B, Rosier RN and Gunter TE (2004) Diazoxide-mediated preconditioning against apoptosis involves activation of CREB and NFkB. Journal of Biological Chemistry 279 46748-46754
Elkon R, Linhart C, Halperin Y, Shiloh Y and Shamir R (2007) Functional genomic delineation of TLR-induced transcriptional networks. BMC Genomics 8 394
Ellinghaus U, Rupec RA, Pabst O, Ignatius R, Forster R, Dorken B and Jundt F (2008) IkBa is required for marginal zone B cell lineage development. European Journal of Immunology in press
Elliott CL, Allport VC, Loudon JA, Wu GD and Bennett PR (2001) Nuclear factor-kB is essential for up-regulation of interleukin-8 expression in human amnion and cervical epithelial cells. Mol Hum Reprod 7 787-790
Elliott S, Hays E, Mayor M, Sporn M and Vincenti M (2003) The triterpenoid CDDO inhibits expression of matrix metalloproteinase-1, matrix metalloproteinase-13 and Bcl-3 in primary human chondrocytes. Arthritis Research and Therapy 5 R285-R291
Elliott SF, Coon CI, Hays E, Stadheim TA and Vincenti MP (2002) Bcl-3 is an interleukin-1-responsive gene in chondrocytes and synovial fibroblasts that activates transcription of the matrix metalloproteinase 1 gene. Arthritis and Rheumatitis 46 3230-3239
Ellis L, Gilston V, Soo CC, Morris CJ, Kidd BL and Winyard PG (2000) Activation of the transcription factor NF-kB in the rat air pouch model of inflammation. Ann Rheum Dis 59 303-307
Ellis RD, Ashwood P, Powell JJ, Taylor PD, Poulsom R, Thompson RP and Punchard NA (2002) Selective binding of nucleotide probes by eosinophilic cationic protein during in situ hybridisation. Histochemistry Journal 34 153-160
Ellis S, Mouihate A and Pittman QJ (2005) Early life immune challenge alters innate immune responses to lipopolysaccharide: implications for host defense as adults. FASEB Journal 19 1519-1521
Elmaleh DR, Brown NV and Geiben-Lynn R (2005) Anti-viral activity of human antithrombin III. International Journal of Molecular Medicine 16 191-200
Elmali N, Baysal O, Harma A, Esenkaya I and Mizrak B (2006) Effects of resveratrol in inflammatory arthritis. Inflammation 30 1-6
Elmali N, Esenkaya I, Harma A, Ertem K, Turkoz Y and Mizrak B (2005) Effect of resveratrol in experimental osteoarthritis in rabbits. Inflammation Research 54 158-162
Elmarkakby AA, Quigley JE, Imig JD, Pollock JS and Pollock DM (2007) TNF-alpha inhibition reduces renal inflammation in DOCA-salt hypertensive rats. American Journal of Physiology: Regulatory, Intergrative and Comparative Physiology in press
Elmarakby AA, Quigley JE, Olearczyk JJ, Sridhar A, Cook AK, Inscho EW, Pollock DM and Imig JD (2007) Chemokine receptor 2b inhibition provides renal protection in angiotensin II salt hypertension. Hypertension in press
El-Rayes BF, Ali S, Philip PA and Sarkar FH (2008) Protein kinase C: a target for therapy in pancreatic cancer. Pancreas 36 346-352
Elsea SH, Mykytyn K, Ferrell K, Coulter KL, Das P, Dubiel W, Patel PI and Metherall JE (1999) Hemizygosity for the COP9 signalosome subunit gene, SGN3, in the Smith-Magenis syndrome. American Journal of Medical Genetics 87 342-348
Elsharkawy AM and Mann DA (2007) Nuclear factor-kappaB and the hepatic inflammation-fibrosis-cancer axis. Hepatology 46 590-597
Elsharkawy AM, Oakley F and Mann DA (2005) The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis. Apoptosis 10 927-939
Elsharkawy AM, Wright MC, Hay RT, Arthur MJ, Hughes T, Bahr MJ, Degitz K and Mann DA (1999) Persistent activation of Nuclear Factor-kB in cultured rat hepatic stellate cells involves the induction of potentially novel Rel-like factors and prolonged changes in the expression of IkB family proteins. Hepatology 30 761-769
Elsherif L, Jiang Y, Saari JT and Kang YJ (2004) Dietary copper restriction-induced changes in myocardial gene expression and the effect of copper repletion. Experimental Biology and Medicine (Maywood) 229 616-622
Elwakkaad AS, El Elshamy KA and Sibaii H (2008) Fish liver oil and propolis as protective natural products against the effect of the anti-epileptic drug valproate on immunological markers of bone formation in rats. Epilepsy Research in press
Ely KR, Kodandapani R and Wu S (2007) Protein-protein interactions in TRAF3.Advances in Experimental Medicine and Biology 597 114-121
Ely KR and Li C (2002) Structurally adaptive hot spots at a protein interaction interface on TRAF3. Journal of Molecular Recognition 15 286-290
Emanuele MA, Emanuele NV, Gamelli RL, Kovacs EJ and Lapaglia N (2007) Effects of insulin on hepatic inflammation induced by ethanol and burn injury in a murine model of critical illness.
Journal of Burn Care Research in press
Emberley Ed, Niu Y, Curtis L, Troup S, Mandal SK, Myers JN, Gibson SB, Murphy LC and Watson PH (2005) The S100A7-c-Jun activation domain binding protein 1 pathway enhances prosurvival pathways in breast cancer. Cancer Research 65 5696-5702
Embree-Ku M and Gruppuso PA (2005) The role of nuclear factor kB in late-gestation liver development in the rat. Hepatology 42 326-334
Emdaad L, Sarkar D, Su ZZ, Lee SG, Kang DC, Bruce JN, Volsky DJ and Fisher PB (2007) Astrocyte elevated gene-1: Recent insights into a novel gene involved in tumor progression, metastasis and neurodegeneration. Pharmacology & Therapeutics in press
Emdad L, Sarkar D, Su ZZ, Randolph A, Boukerche H, Valerie K and Fisher PB (2006) Activation of the nuclear factor kB pathway by astrocyte elevated gene-1: implications for tumor progression and metastasis. Cancer Research 66 1509-1516
Emelyanov A and Parinov S (2008) Mifepristone-inducible LexPR system to drive and control gene expression in transgenic zebrafish. Developmental Biology in press
Emmerich F, Meiser M, Hummel M, Demel G, Foss HD, Jundt F, Mathas S, Krappmann D, Scheidereit C, Stein H and Dorken B (1999) Overexpression of IkBa without inhibition of NF-kB activity and mutations in the IkBa gene in Reed-Sternberg cells. Blood 94 3129-3134
Emmerich F, Theurich S, Hummel M, Haeffker A, Vry MS, Dohner K, Bommert K, Stein H, Dorken B (2003) Inactivating IkBepsilon mutations in Hodgkin/Reed-Sternberg cells. Journal of Pathology 201 413-420
Endo K, Hirata A, Iwai K, Sakurai M, Fukushi M, Oie Masayasu, Higuchi M, Hall WW, Gejyo F and Fujii M (2002) Human T-cell Leukemia Virus Type 2 (HTLV-2) Tax protein transforms a rat fibroblast cell line but less efficiently than HTLV-1 Tax. Journal of Virology 76 2648-2653
Endo T, Nishio M, Enzler T, Cottam HB, Fukuda T, James DF, Karin M and Kipps TJ (2007) BAFF And APRIL support chronic lymphocytic leukemia B cell survival through activation of the canonical NF-kB pathway. Blood 109 703-710
Endo Y, Marusawa H, Kinoshita K,Morisawa T, Sakurai T, Okazaki IM, Watashi K, Shimotohno K, Honjo T and Chiba T (2007) Expression of activation-induced cytidine deaminase in human hepatocytes via NF-kB signaling. Oncogene in press
Endres R, Hacker G, Brosch I and Pfeffer K (2003) Apparently normal tumor necrosis factor receptor 1 signaling in the absence of the silencer of death domains. Molecular and Cellular Biology 23 6609-6617
Enesa K, Ito K, Luong LA, Thorbjornsen I, Phua C, To Y, Dean J, Haskard DO, BOyle J, Adcock I and Evans PC (2008) Hydrogen peroxide prolongs nuclear localization of NF-kB in activated cells by suppressing negative regulatory mechanisms. Journal of Biological Chemistry 283 18582-18590
Enesa K, Zakkar M, Chaudhury H, Luong LA, Rawlinson L, Mason JC, Haskard DO, Dean JL and Evans PC (2008) NF-kB suppression by the deubiquitinating enzyme cezanne: a novel negative feedback loop in pro-inflammatory signaling. Journal of Biological Chemistry 283 7036-7045
Eng E and Ballermann BJ (2003) Diminished NF-kB activation and PDGF-B expression in glomerular endothelial cells subjected to chronic shear stress. Microvascular Research 65 137-144
Engedal N and Blomhoff HK (2003) Combined action of ERK and NFkB mediates the protective effect of phorbol Ester on Fas-induced apoptosis in Jurkat cells. Journal of Biological Chemistry 278 10934-10941
Engelmann B, Zieseniss S, Brand K, Page S, Lentschat A, Ulmer AJ and Gerlach E (1999) Tissue factor expression of human monocytes is suppressed by lysophosphatidylcholine. Arterioscler Thromb Vasc Biol 19 47-53
Engelsma MY, Stet RJ, Saeij JP and Verburg-van Kemenade BM (2003) Differential expression and haplotypic variation of two interleukin-1beta genes in the common carp (Cyprinus carpio L.). Cytokine 22 21-32
Engidawork E, Gulesserian T, Seidl R, Cairns N, Lubec G (2002) Expression of apoptosis related proteins: RAIDD, ZIP kinase, Bim/BOD, p21, Bax, Bcl-2 and NF-kB in brains of patients with Down syndrome. J Neural Transm Suppl 61 181-192
Englaro W, Bahadoran P, Bertolotto C, Buscà R, Dérijard B, Livolsi A, Peyron J-F, Ortonne J-P and Ballotti R (1999) Tumor necrosis factor alpha-mediated inhibition of malanogenesis is dependent on nuclear factor kB activation. Oncogene 18 1553-1559
Engler H, Bailey MT, Engler A, Stiner-Jones LM, Quan N and Sheridan JF (2007) Interleukin-1 receptor type 1-deficient mice fail to develop social stress-associated glucocorticoid resistance in the spleen. Psychoneuroendocrinology in press
English K, Brady C, Corcoran P, Cassidy JP and Mahon BP (2005) Inflammation of the respiratory tract is associated with CCL28 and CCR10 expression in a murine model of allergic asthma. Immunology Letters 103 92-100
Englund G, Hoggan MD, Theodore TS and Martin MA (1991) A novel HIV-1 isolate containing alterations affecting the NF-kB element. Virology 181 150-157
Englund MC, Karlsson AL, Wiklund O, Bondjers G and Ohlsson BG (2001) 25-hydroxycholesterol induces lipopolysaccharide-tolerance and decreases a lipopolysaccharide-induced TNF-a secretion in macrophages. Atherosclerosis 158 61-71
Engström Y, Kadalayil L, Sun S-C, Samakovlis C, Hultmark D and Faye I (1993) kB-like motifs regulate the induction of immune genes in Drosophila. Journal of Molecular Biology 232 327-333
Ennaciri J, Ahmad R, and Memezes J (2006) Interaction of monocytic cells with respiratory syncytial virus results in activation of NF-kB and PKC-a/b leading to up-regulation of IL-15 gene expression. Journal of Leukocyte Biology in press
Enrietto PJ (1991) The rel gene and its role in oncogenesis. Seminars in Cancer Biology 1 399-405
Enrietto PJ (1990) Avian reticuloendotheliosis. In, Encyclopedia of Virology (Eds. Robert G. Webster and Allan Granoff) pp
Entrican G, Wattegedera S, Rocchi M, Fleming DC, Kelly RW, Wathne G, Magdalenic V and Howie SE (2004) Induction of inflammatory host immune responses by organisms belonging to the genera Chlamydia/Chlamydophila. Vet Immunol Immunopathol 100 179-186
Enzler T, Bonizzi G, Silverman GJ, Otero DC, Widhopf GF, Anzelon-Mills A, Rickert RC adn Karin M (2006) Alternative and classical NF-kB signaling retain autoreactive B cells in the splenic marginal zone and result in lupus-like disease. Immunity 25 403-415
Eom YW, Kim MA, Park SS, Goo MJ, Kwon HJ, Sohn S, Kim WH, Yoon G and Choi KS (2005) Two distinct modes of cell death induced by doxorubicin: apoptosis and cell death through mitotic catastrophe accompanied by senescence-like phenotype. Oncogene 24 4765-4777
Epinat JC and Gilmore TD (1999) Diverse agents act at multiple levels to inhibit the Rel/NF-kB signal transduction pathway. Oncogene 18 6896-6909
Epinat JC, Dvorin EL and Gilmore TD (2000) Envelope-dependent transactivation by the retroviral oncoprotein v-Rel is required for efficient malignant transformation of chicken spleen cells. Oncogene 19 3131-3137
Epinat JC, Kazandjian D, Harkness DD, Petros S, Dave J, White DW and Gilmore TD (2000) Mutant envelope residues confer a transactivation function onto N-terminal sequences of the v-Rel oncoprotein. Oncogene 19 599-607
Epinat J-C, Whiteside ST, Rice NR and Israël A (1997) Reconstitution of the NF-kB system in Saccharomyces cerevisiae for isolation of effectors by phenotype modulation. Yeast 13 599-612
Equils O, Faure E, Thomas L, Bulut Y, Trushin S and Arditi M (2001) Bacterial lipopolysaccharide activates HIV long terminal repeat through Toll-like receptor 4. Journal of Immunology 166 2342-2347
Equils O, Madak Z, Liu C, Michelsen KS, Bulut Y and Lu D (2004) Rac1 and Toll-IL-1 receptor domain-containing adapter protein mediate Toll-like receptor 4 induction of HIV long terminal repeat. Journal of Immunology 172 7642-7646
Equils O, Naiki Y, Shapiro AM, Michelsen K, Lu D, Adams J and Jordan S (2006) 1,25-Dihydroxyvitamin D inhibits lipopolysaccharide-induced immune activation in human endothelial cells. Clinical and Experimental Immunology 143 58-64
Equils O, Shapiro A, Madak Z, Liu C and Lu D (2004) Human immunodeficiency virus type 1 protease inhibitors block Toll-like receptor 2 (TLR2)- and TLR4-induced NF-kB activation. Antimicrobial Agents and Chemotherapy 48 3905-3911
Erbil Y, Giris M, Abbasoglu SD, Barbaros U, Yanik BT, Necefli A, Olgac V and Toker GA (2007) Effect of heme oxygenase-1 induction by octreotide on TNBS-induced colitis. Journal of Gastroenterology and Hepatology 22 1852-1858
Erbil Y, Oztezcan S, Giris M, Barbaros U, Olgac V, Bilge H, Kucucuk H and Toker G (2005) The effect of glutamine on radiation-induced organ damage. Life Sciences 78 376-382
Erdman S, Fox JG, Dangler CA, Feldman D and Horwitz BH (2001) Typhlocolitis in NF-kB-deficient mice. Journal of Immunology 166 1443-1447
Erfurth SE, Grobner S, Kramer U, Gunst DS, Soldanova I, Schaller M, Autenrieth IB and Borgmann S (2004) Yersinia enterocolitica induces apoptosis and inhibits surface molecule expression and cytokine production in murine dendritic cells. Infection and Immunity 72 7045-7054
Erickson KD, Berger C, Coffin WF 3rd, Schiff E, Walling DM and Martin JM (2003) Unexpected absence of the Epstein-Barr Virus (EBV) lyLMP-1 open reading frame in tumor virus isolates: lack of correlation between Met129 status and EBV strain identity. Journal of Virology 77 4415-4422
Erickson KD and Martin JM (2000) The late lytic LMP-1 protein of Epstein-Barr virus can negatively regulate LMP-1 signaling. Journal of Virology 74 1057-1060
Erkel G, Wisser G and Anke T (2007) Influence of the fungal NF-kB inhibitor panepoxydone on inflammatory gene expression in MonoMac6 cells. InternationalImmunopharmacology 7 612-624
Erl W, Hansson GK, de Martin R, Draude G, Weber KS and Weber C (1999) Nuclear factor-kappa B regulates induction of apoptosis and inhibitor of apoptosis protein-1 expression in vascular smooth muscle cells. Circulation Research 84 668-677
Erlandsson AC, Bladh LG, Stierna P, Yucel-Lindberg T, Hammarsten O, Modeer T, Harmenberg J and Wikstrom AC (2002) Herpes simplex virus type 1 infection and glucocorticoid treatment regulate viral yield, glucocorticoid receptor and NF-kB levels. Journal of Endocrinology 175 165-176
Erlandsson N, Baumann B, Rossler OG, Kaufmann K, Giehl KM, Wirth T and Thiel G. (2002) Lack of correlation between NF-kB activation and induction of programmed cell death in PC12 pheochromocytoma cells treated with 6-hydroxydopamine or the cannabinoid receptor 1-agonist CP55,940. Biochemical Pharmacology 64 487-495
Erlejman AG, Jaggers G, Fraga CG and Oteiza PI (2008) TNFa-induced NF-kB activation and cell oxidant production are modulated by hexameric procyanidins in Caco-2 cells. Archives of Biochemistry and Biophysics in press
Ermolaeva MA, Michallet MC, Papadopoulou N, Utermohlen O, Kranidioti K, Kollias G, Tschopp J, Pasparakis M (2008) Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses. Nature Immunology in press
Ernfors P (2000) Nuclear factor-kB to the rescue of cytokine-induced neuronal survival [comment]. Journal of Cell Biology 148 223-225
Ernst MK, Dunn LL and Rice NR (1995) The PEST-like sequence of IkBa is responsible for inhibition of DNA binding but not for cytoplasmic retention of c-rel or RelA homodimers. Molecular and Cellular Biology 15 872-882
Erol A (2005) PPARa activators may be good candidates as antiaging agents.Medical Hypotheses 65 35-38
Erridge C, Kennedy S, Spickett CM and Webb DJ (2008) Oxidised phospholipid inhibition of toll-like receptor (TLR) signalling is restricted to TLR2 and TLR4 – roles for CD14, LPS-binding protein and MD2 as targets for specificity of inhibition. Journal of Biological Chemistry in press
Erridge C, Pridmore A, Eley A, Stewart J and Poxton IR (2004) Lipopolysaccharides of Bacteroides fragilis, Chlamydia trachomatis and Pseudomonas aeruginosa signal via Toll-like receptor 2. Journal of Medical Microbiology 53 735-740
Erridge C, Webb DJ and Spickett CM (2006) Toll-like receptor 4 signalling is neither sufficient nor required for oxidised phospholipid mediated induction of interleukin-8 expression. Atherosclerosis in press
Errington F, Steele L, Prestwich R, Harrington KJ, Pandha HS, Vidal L, de Bono J, Selby P, Coffey M, Vile R and Melcher A (2008) Reovirus activates human dendritic cells to promote innate antitumor immunity. Journal of Immunology 180 6018-6026
Escalante CR, Shen L, Thanos D and Aggarwal AK (2002) Structure of NF-kB p50/p65 heterodimer bound to the PRDII DNA element from the interferon-beta promoter. Structure 10 383-391
Escarcega RO, Fuentes-Alexandro S, Garcia-Carrasco M, Gatica A and Zamora A (2007) The transcription factor nuclear factor-kappa B and cancer. ClinicalOncology (Royal College of Radiologists 19 154-161
Escobar-Diaz E, Lopez-Martin EM, Hernandez Del Cerro M, Puig-Kroger A, Soto-Cerrato V, Montaner B, Giralt E, Garcia-Marco JA, Perez-Tomas R and Garcia-Pardo A (2005) AT514, a cyclic depsipeptide from Serratia marcescens, induces apoptosis of B-chronic lymphocytic leukemia cells: interference with the Akt/NF-kB survival pathway. Leukemia 19 572-579
Escotte S, Tabary O, Dusser D, Majer-Teboul C, Puchelle E and Jacquot J (2003) Fluticasone reduces IL-6 and IL-8 production of cystic fibrosis bronchial epithelial cells via IKK-beta kinase pathway. European Respiratory Journal 21 574-581
Escribano J, Diaz-Guerra MJ, Riese HH, Ontanon J, Garcia-Olmo D, Garcia-Olmo DC, Rubio A and Fernandez JA (1999) In vitro activation of macrophages by a novel proteoglycan isolated from corms of Crocus sativus L. Cancer Letters 144 107-114
Escudero C and Sobrevia L (2008) A hypothesis for preeclampsia: adenosine and inducible nitric oxide synthase in human placental microvascular endothelium. Placenta in press
Eskandarpour M, Kiaii S, Zhu C, Castro J, Sakko AJ and Hansson J (2005) Suppression of oncogenic NRAS by RNA interference induces apoptosis of human melanoma cells. International Journal of Cancer 115 65-73
Eskew JD, Vanacore RM, Sung L, Morales PJ and Smith A (1999) Cellular protection mechanisms against extracellular heme. heme-hemopexin, but not free heme, activates the N-terminal c-jun kinase. Journal of Biological Chemistry 274 638-648
Esmon CT (2001) Protein C anticoagulant pathway and its role in controlling microvascular thrombosis and inflammation. Crit Care Med 29 S48-S51; discussion 51-42
Esmon CT (2003) Protein C pathway in sepsis. Annals of Medicine 34 598-605
Espandiari P, Ludweig G, Glauert HP and Robertson LW (1998) Activation of hepatic NF-kB by the herbicide Dicamba (2-methoxy-3,6-dichlorobenzoic acid) in female and male rats. Journal of Molecular Toxicology 12 339-344
Esparza EM and Arch RH (2004) TRAF4 functions as an intermediate of GITR-induced NF-kB activation. Cellular and Molecular Life Sciences 61 3087-3092
Esparza EM and Arch RH (2005) Glucocorticoid-induced TNF receptor functions as a costimulatory receptor that promotes survival in early phases of T cell activation. Journal of Immunology 174 7869-7874
Esparza EM and Arch RH (2005) Glucocorticoid-induced TNF receptor, a costimulatory receptor on naive and activated T cells, uses TNF-receptor-associated factor 2 in a novel fashion as an inhibitor of NF-kB activation.Journal of Immunology 174 7875-7882
Esparza EM, Lindsten T, Stockhausen JM and Arch RH (2006) Tumor necrosis factor receptor (TNFR) associated factor 5 is a critical intermediate of costimulatory signaling pathways triggered by glucocorticoid-induced TNFR in T cells. Journal of Biological Chemistry 281 8559-8564
Espert L, Rey C, Gonzalez L, Degols G, Chelbi-Alix MK, Mechti N and Gongora C (2004) The exonuclease ISG20 is directly induced by synthetic dsRNA via NF-kB and IRF1 activation. Oncogene 23 4636-4640
Espevik T, Latz E, Lien E, Monks B and Golenbock DT (2003) Cell distributions and functions of Toll-like receptor 4 studied by fluorescent gene constructs. Scandinavian Journal of Infectious Disease 35 660-664
Espindola RD, Mazzantini RP, Ong TP, Conti AD, Heidor R and Moreno FS (2005) Geranylgeraniol and beta-ionone inhibit hepatic preneoplastic lesions, cell proliferation, total plasma cholesterol and DNA damage during the initial phases of hepatocarcinogenesis, but only the former inhibits NF-kB activation. Carcinogenesis 26 1091-1099
Espinola RG, Liu X, Colden-Stanfield M, Hall J, Harris EN and Pierangeli SS (2003) E-Selectin mediates pathogenic effects of antiphospholipid antibodies. Journal of Thrombosis and Haemostosis 1 843-848
Espinosa L, Ingles-Esteve J, Robert-Moreno A, Bigas A (2003) IkBa and p65 regulate the cytoplasmic shuttling of nuclear corepressors: cross-talk between Notch and NFkB pathways. Molecular Biology of the Cell 14 491-502
Espinosa L, Santos S, Ingles-Esteve J, Munoz-Canoves P and Bigas A (2002) p65-NFkB synergizes with Notch to activate transcription by triggering cytoplasmic translocation of the nuclear receptor corepressor N-CoR. Journal of Cell Science 115 1295-1303
Espinoza LA, Smulson ME and Chen Z (2007) Prolonged poly(ADP-ribose) polymerase-1 activity regulates JP-8-induced sustained cytokine expression in alveolar macrophages.
Free Radical Biology and Medicine. 42 1430-1440
Espinoza LA, Tenzin F, Cecchi AO, Witten ML and Smulson ME (2006) Expression of JP-8-induced inflammatory genes in AEII cells is mediated by NF-kB and PARP-1.American Journal of Respiratory Cell and Molecular Biology 35 479-487
Esposito E, Iacono A< Muia C, Crisafulli C, Mattace Raso G, Bramanti P, Meli R and Cuzzocrea S (2008) Signal transduction pathways involved in protective effects of melatonin in C6 glioma cells. Journal of Pineal Research 44 78-87
Esposito E, Rotilio D, Di Matteo V, Di Giulio C, Cacchio M and Algeri S (2002) A review of specific dietary antioxidants and the effects on biochemical mechanisms related to neurodegenerative processes. Neurobiology of Aging 23 719-735
Esposito G, de Fillipis D, Cirillo C, Sarnelli G, Cuomo R and Iuvone T (2006) The astroglial-derived S100beta protein stimulates the expression of nitric oxide synthase in rodent macrophages through p38 MAP kinase activation. Life Sciences 78 2707-2715
Esposito G, De Fillippis D, Maiuri MC, De Stefano D, Carnuccio R and Iuvone T (2006) Cannabidiol inhibits inducible nitric oxide synthase protein expression and nitric oxide production in beta-amyloid stimulated PC12 neurons through p38 MAP kinase and NF-kB involvement. Neurosci Letters 404 342-346
Essani NA, Fisher MA, Jaeschke H (1997) Inhibition of NF-kB activation by dimethyl sulfoxide correlates with suppression of TNF-a formation, reduced ICAM-1 gene transcription, and protection against endotoxin-induced liver injury. Shock 7 90-96
Essawy MM, Nafeh AI, Ezzat HM, Elsebae MM, Marei SA, Salama AF and Badawy AA (2007) The effect of portal vein branch plus heterochronous hepatic artery branch ligation on liver regeneration (experimental study). Journal of the Egyptian Society of Parastilogy 37 557-570
Esslinger CW, Jongeneel CV and MacDonald HR (1998) Survival-independent function of NF-kB/Rel during late stages of thymocyte differentiation. Molecular Immunology 35 847-852
Esslinger CW, Wilson A, Sordat B, Beermann F and Jongeneel V (1997) Abnormal T lymphocyte development induced by targeted overexpression of IkBa. Journal of Immunology 158 5075-5078
Esteban V, Lorenzo O, Ruperez M, Suzuki Y, Mezzano S, Blanco J, Kretzler M, Sugaya T, Egido J and Ruiz-Ortega M (2004) Angiotensin II, via AT(1) and AT(2) receptors and NF-kB pathway, regulates the inflammatory response in unilateral ureteral obstruction. Journal of the American Society of Nephrology 15 1514-1529
Esteban V, Ruperez M, Sanchez-Lopez E, Rodriguez-Vita J, Lorenzo O, Demaegdt H, Vanderheyden P, Egido J and Ruiz-Ortega M (2005) Angiotensin IV activates the nuclear transcription factor-kB and related proinflammatory genes in vascular smooth muscle cells. Circulation Research 96 965-973
Estelles A, Charlton CA and Blau HM (1999) The phosphoprotein protein PEA-15 inhibits Fas- but increases TNF-R1-mediated caspase-8 activity and apoptosis. Developmental Biology 216 16-28
Esteve PO, Chicoine E, Robledo O, Aoudjit F, Descoteaux A, Potworowski EF and St-Pierre Y (2002)
Protein kinase c-zeta regulates transcription of the matrix metalloproteinase-9 gene induced by IL-1 and TNF-alpha in glioma cells via NF-kB. Journal of Biological Chemistry 277 35150-35155
Estrada-Bernal A, Mendoza-Milla C, Ventura-Gallegos JL, Lopez-Bojorquez LN, Miranda-Peralta E, Arechavaleta-Velasco F, Vadillo-Ortega F, Sanchez-Sanchez L and Zentella-Dehesa A (2003) NF-kB dependent activation of human endothelial cells treated with soluble products from human lymphomas. Cancer Letters 191 239-248
Estrov Z, Manna SK, Harris D, Van Q, Kantarjian HM, Talpaz HM and Aggarwal BB (1999) Phenylarsine oxide (PAO) blocks interleukin (IL)-1b-induced activation of the nuclear transcription factor NF-kB, inhibits proliferation, and induces apoptosis of acute myelogenous leukemia (AML) cells. Blood 94 2844-2853
Estrov Z, Shishodia S, Faderl S, Harris D, Van Q, Kantarjian HM, Talpaz M and Aggarwal BB (2003) Resveratrol blocks interleukin-1{beta}-induced activation of the nuclear transcription factor NF-kB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells. Blood 102 987-995
Eswarappa SM, Basu N, Joy O and CHakravaorthy D (2008) Folimycin (concanamycin A) inhibits LPS-induced nitric oxide production and reduces surface localization of TLR4 in murine macrophages. Innate Immunity 14 13-24
Etemad-Moghadam B, Chen H, Yin P, Aziz N and Hedley ML (2002) Inhibition of NF-kB activity by plasmid expressed alphaMSH peptide. Journal of Neuroimmunology 125 23-29
Eter EE, Hagar HH, AL-Tuwaijiri A and Arafa M (2005) Nuclear factor-kB inhibition by pyrrolidinedithiocarbamate attenuates gastric ischemia-reperfusion injury in rats. Canadian Journal of Physiology and Pharmacology 83 483-492
Ethuin F, Delarche C, Benslama S, Gougerot-Pocidalo MA, Jacob L and Chollet-Martin S (2001) Interleukin-12 increases interleukin 8 production and release by human polymorphonuclear neutrophils. Journal of Leukocyte Biology 70 439-446
Ethridge RT, Hashimoto K, Chung DH, Ehlers RA, Rajaraman S and Evers BM (2002) Selective inhibition of NF-kB attenuates the severity of cerulein-induced acute pancreatitis. Journal of the American College of Surgery 195 497-505
Eto A, Muta T, Yamazaki S and Takeshige K (2003) Essential roles for NF-kB and a Toll/IL-1 receptor domain-specific signal(s) in the induction of IkB-zeta. Biochemical and Biophysical Research Communications 301 495-501
Eto M, Kouroedov A, Cosentino F and Luscher TF (2005) Glycogen synthase kinase-3 mediates endothelial cell activation by tumor necrosis factor-alpha. Circulation 112 1316-1322
Etten EV and Mathieu C (2005) Immunoregulation by 1,25-dihydroxyvitamin D(3): basic concepts. Journal of Steriod Biochemistry and Molecular Biology 97 93-101
Etzioni A and Ochs HD (2004) The hyper IgM syndrome–an evolving story. Pediatrics Research 56 519-525
Eum SY, Lee YW, Hennig B and Toborek M (2004) VEGF regulates PCB 104-mediated stimulation of permeability and transmigration of breast cancer cells in human microvascular endothelial cells. Experimental Cell Research 296 231-244
Eum SY, Rha GB, Hennig B and Toborek M (2006) C-Src is the primary signaling mediator of PCB-induced interleukin-8 expression in a human microvascular endothelial cell line.
Toxicological Sciences 92 311-320
Eun CS, Han DS, Lee SH, Jeon YC, Sohn JH, Kim YS and Lee J (2007) Probiotics may reduce inflammation by enhancing peroxisome proliferator activated receptor g activation in HT-29 cells [Article in Chinese]. Korean Journal of Gastroenterology 49 139-146
Eun CS, Han DS, Lee SH, Paik CH, Chung YW, Lee J and Hahm JS (2006) Attenuation of colonic inflammation by PPARg in intestinal epithelial cells: effect on Toll-like receptor pathway. Digestive Diseases and Sciences 51 693-697
Evan GI and Vousden KH (2001) Proliferation, cell cycle and apoptosis in cancer. Nature 411 342-348
Evans I, Dower SK, Francis SE, Crossman DC and WIlson HL (2006) Action of intracellular IL-1Ra (Type 1) is independent of the IL-1 intracellular signalling pathway. Cytokine 33 274-280
Evans JD and Seeger C (2006) Cardif: A protein central to innate immunity is inactivated by the HCV NS3 serine protease. Hepatology 43 615-617
Evans JL, Maddux BA and Godlfin ID (2005) The molecular basis for oxidative stress-induced insulin resistances. Antioxid Redox Signal 7 1040-1052
Evans KE and Fox SW (2007) Interleukin-10 inhibits osteoclastogenesis by reducing NFATc1 expression and preventing its translocation to the nucleus. BMC Cell Biology 8 4
Evans MJ, Eckert A, Lai K, Adelman SJ and Harnish DC (2001) Reciprocal antagonism between estrogen receptor and NF-kB activity in vivo. Circulation Research 89 823-830
Evans PC (2005) Regulation of pro-inflammatory signalling networks by ubiquitin: identification of novel targets for anti-inflammatory drugs. Expert Reviews in Molecular Medicine 7 1-19
Evans PC, Ovaa H, Hamon M, Kilshaw PJ, Hamm S, Bauer S, Ploegh HL and Smith TS (2004) A20, a regulator of inflammation and cell survival, has deubiquitinating activity. Biochemical Journal 378 727-734
Evans PC, Smith TS, Lai MJ, Williams MG, Burke DF, Heyninck K, Kreike MM, Beyaert R, Blundell TL and Kilshaw PJ (2003) A novel type of deubiquitinating enzyme. Journal of Biological Chemistry 278 23180-23186
Evans PC, Taylor ER, Coadwell J, Heyninck K, Beyaert R and Kilshaw PJ (2001) Isolation and characterization of two novel A20-like proteins. Biochemical Journal 357 617-623
Evans RB, Gottleib PD and Bose Jr HR (1993) Identification of a Rel-related protein in the nucleus during S phase of the cell cycle. Molecular and Cellular Biology 13 6147-6156
Evans SE, Hahn PY, McCann F, Kottom TJ, Vuk Pavlovic Z and Limper AH (2005) Pneumocystis beta-glucans Stimulate epithelial cell chemokine generation through NF-kB mechanisms. American Journal of Respiratory Cell and Molecular Biology 32 490-497
Evans-Storms RB and Cidlowski JA (2000) Delineation of an antiapoptotic action of glucocorticoids in hepatoma cells: the role of nuclear factor-kB. Endocrinology 141 1854-1862
Everett PC, Meyers JA, Makkinje A, Rabbi M and Lerner A (2006) Preclinical assessment of curcumin as a potential therapy for B-CLL. American Journal of Hematology in press
Everhart MB, Han W, Parman KS, Polosukhin VV, Zeng H, Sadikot RT, Li B, Yull FE, Christman JW and Blackwell TS (2004) Intratracheal administration of liposomal clodronate accelerates alveolar macrophage reconstitution following fetal liver transplantation. Journal of Leukocyte Biology 77 173-180
Everhart MB, Han W, Sherrill TP, Arutiunov M, Polosukhim VV, Burke JR, Sadikot RT, Christman JW, Yull FE and Blackwell TS (2006) Duration and intensity of NF-kB activity determine the severity of endotoxin-induced acute lung injury. Journal of Immunology ;176 4995-5005
Everly DN Jr, Kusano S and Raab-Traub N (2004) Accumulation of cytoplasmic b-catenin and nuclear glycogen synthase kinase 3b in Epstein-Barr Virus-infected cells. Journal of Virology 78 11648-11655
Evers DL, Chao CF, Wang X, Zhang Z, Huong SM and Huang ES (2005) Human cytomegalovirus-inhibitory flavonoids: Studies on antiviral activity and mechanism of action. Antiviral Research 68 124-134
Evers DL, Wang X, Huong SM, Andreoni KA and Huang ES (2005) Inhibition of human cytomegalovirus signaling and replication by the immunosuppressant FK778. Antiviral Research 65 1-12
Evers DL, Wang X, Huong SM, Huang DY and Huang ES (2004) 3,4′,5-Trihydroxy-trans-stilbene (resveratrol) inhibits human cytomegalovirus replication and virus-induced cellular signaling. Antiviral Research 63 85-95
Evertsson S and Sun XF (2002) Protein expression of NF-kB in human colorectal adenocarcinoma. International Journal of Molecular Medicine 10 547-550
Eves P, Haycock J, Layton C, Wagner M, Kemp H, Szabo M, Morandini R, Ghanem G, Garcia-Borron JC, Jimenez-Cervantes C and Mac Neil S (2003) Anti-inflammatory and anti-invasive effects of alpha-melanocyte-stimulating hormone in human melanoma cells. British Journal of Cancer 89 2004-2015
Ezzell C (1997) Protein folding and the early secretory pathway: researchers begin to understand the cellular assembly line. Journal of NIH Research 9 42-47