References – L
La E and Fischer SM (2001) Transcriptional regulation of intracellular IL-1 receptor antagonist gene by IL-1 alpha in primary mouse keratinocytes. Journal of Immunology 166 6149-6155
La S, Kim J, Kwon BS and Kwon B (2002) Herpes simplex virus type 1 glycoprotein D inhibits T-cell proliferation. Mol Cells 14 398-403
La Ferla K, Reimann C, Jelkmann W and Hellwig-Burgel T (2002) Inhibition of erythropoietin gene expression signaling involves the transcription factors GATA-2 and NF-kB. FASEB Journal 16 1811-1813
La Ferla K, Seegert D and Schreiber S (2004) Activation of NF-kB in intestinal epithelial cells by E. coli strains isolated from the colonic mucosa of IBD patients. International Journal of Colorectal Disease 19 334-342
La Feurla-Bruhl K, Westhoff MA, Karl S, Kasperczyk H, Zwacka RM, Debatin KM and Fulda S (2007) NF-kB-independent sensitization of glioblastoma cells for TRAIL-induced apoptosis by proteasome inhibition. Oncogene 26 571-582
La Frazia S, Amici C and Santoro MG (2006) Antiviral activity of proteasome inhibitors in herpes simplex virus-1 infection: role of nuclear factor-kB. Antiviral Therapy 11 995-1004
La Grutta S, Gagliardo R, Mirabella F, Pajno GB, Bonsignore G, Bousquet J, Bellia V and Vignola AM (2003) Clinical and biological heterogeneity in children with moderate asthma. American Journal of Respiratroy Critical Care Medicine 167 1490-1495
La Porta CA, Comolli R (1998) PKC-dependent modulation of IkBa-NFkB pathway in low metastatic B16F1 murine melanoma cells and in highly metastatic BL6 cells. Anticancer Research 18 2591-2597
La Rosa FA, Pierce JW and Sonenshein GE (1994) Differential regulation of the c-myc oncogene promoter by the NF-kB Rel family of transcription factors. Molecular and Cellular Biology 14 1039-1044
La Rosa G, Cardali S, Genovese T, Conti A, Di Paola R, La Torre D, Cacciola F and Cuzzocrea S (2004) Inhibition of the nuclear factor-kB activation with pyrrolidine dithiocarbamate attenuating inflammation and oxidative stress after experimental spinal cord trauma in rats. J Neurosurg Spine 1 311-321
Laabi Y and Strasser A (2000) Immunology. Lymphocyte survival-ignorance is Blys. Science 289 883-884
Laan M, Bozinovski S and Anderson GP (2004) Cigarette smoke inhibits lipopolysaccharide-induced production of inflammatory cytokines by suppressing the activation of activator protein-1 in bronchial epithelial cells. Journal of Immunology 173 4164-4170
Labbe C, Goyette P, Lefebvre C, Stevens C, Green T, Tello-Ruiz MK, Cao Z, Landry AL, Stempak J, Annese V, Latiano A, Brant SR, Duerr RH, Taylor KD, Cho JH, Steinhart AH, Daly MJ, Silverberg MS, Xavier RJ and Rioux JD (2008) MAST3: a novel IBD risk factor that modulates TLR4 signaling. Genes & Immunity in press
Labbozzetta M, Notarbartolo M, Poma P, Giannitrapani L, Cervello M, Montalto G and D’Alessandro N (2006) Significance of autologous interleukin-6 production in the HA22T/VGH cell model of hepatocellular carcinoma. Annals of the New York Academy of Sciences 1089 268-275
Lacana E and D’Adamio L (1999) Regulation of Fas ligand expression and cell death by apoptosis-linked gene 4. Nature Medicine 5 542-547
Lacasa D, Taleb S, Keophiphath M, Miranville A and Clement K (2006) Macrophage-secreted factors impair human adipogenesis: involvement of proinflmmatory state in preadipocytes. Endocrinology in press
LaCasse EC, Baird S, Korneluk RG and MacKenzie AE (1998) The inhibitors of apoptosis (IAPs) and their emerging role in cancer. Oncogene 17 3247-3259
Lacey D, Sampey A, Mitchell R, Bucala R, Santos L, Leech M and Morand E (2003) Control of fibroblast-like synoviocyte proliferation by macrophage migration inhibitory factor. Arthritis and Rheumatitis 48 103-109
Lacey DL, Tan HL, Lu J, Kaufman S, Van G, Qiu W, Rattan A, Scully S, Fletcher F, Juan T, Kelley M, Burgess TL, Boyle WJ and Polverino AJ (2000) Osteoprotegerin ligand modulates murine osteoclast survival in vitro and in vivo. American Journal of Pathology 157 435-448
Lackman RL and Cresswell P (2006) Exposure of the promonocytic cell line THP-1 to Escherichia coli induces IFN-g-inducible lysosomal thiol reductase expression by inflammatory cytokines.
Journal of Immunology 177 4833-4840
Lacoste J, Cohen L and Hiscott J (1991) NF-kB activity in T cells stably expressing the Tax protein of human T cell lymphotropic virus type I. Virology 184 553-562
Lacoste J, D’Addario M, Roulston A, Wainberg MA and Hiscott J (1990) Cell-specific differences in activation of NF-kB regulatory elements of human immunodeficiency virus and beta interferon promoters by tumor necrosis factor. Journal of Virology 64 4726-4734
Lacoste J, Lanoix J, Pépin N and Hiscott J (1994) Interactions between HTLV-I Tax and NF-kB/Rel proteins in T cells. Leukemia 8 S71-S76
Lacoste J, Petropoulos L, Pépin N and Hiscott J (1994) Constitutive phosphorylation and turnover of IkBa in human T-cell leukemia virus type I-infected and Tax-expressing cells. Journal of Virology 69 564-569
Lacoste V, Nicot C, Gessain A, Valensi F, Gabarre J, Matta H, Chaudhary PM and Mahieux R (2007) In primary effusion lymphoma cells, MYB transcriptional repression is associated with v-FLIP expression during latent KSHV infection while both v-FLIP and v-GPCR become involved during the lytic cycle. BritishJournal of Haematology 138 487-501
Lad SP, Li J, da Silva Correia J, Pan Q, Gadwal S, Ulevitch RJ and Li E (2007) Cleavage of p65/RelA of the NF-kB pathway by Chlamydia. Proceedings of theNational Academy of Sciences USA 104 2933-2938
Lad SP, Yang G, Scott DA, Chao TH, Correia JD, de lat Torre JC and Le E (2008) Identification of MAVS splicing variants that interfere with RIGI/MAVS pathway signaling. Molecular Immunology in press
Lad SP, Yang G, Scott DA, Wang G, Nair P, Mathison J, Reddy VS and L E (2007) Chlamydial CT441 is a PDZ domain-containing tail-specific protease, that interferes with the NF-kB pathway of immune response. Journal of Bacteriology in press
Lademarco MF, McQuillan JJ, Rosen GD and Dean DC (1992) Characterization of the promoter for vascular cell adhesion molecule-1 (VCAM-1). Journal of Biological Chemistry 267 16323-16329
Laderach D, Compagno D, Danos O, Vainchenker W and Galy A (2003) RNA interference shows critical requirement for NF-kB p50 in the production of IL-12 by human dendritic cells. Journal of Immunology 171 1750-1757
Ladetzki-Baehs K, Keller M, Kiemer AK, Koch E, Zahler S, Wendel A and Vollmar AM (2007) Atrial natriuretic peptide (ANP)-A regulator of NF-kB activation in vivo. Endocrinology 148 332-336
Ladner KJ, Caligiuri MA and Guttridge DC (2003) TNF regulated biphasic activation of NF-kB is required for cytokine-induced loss of skeletal muscle gene products. Journal of Biological Chemistry 278 2294-2303
Lafarge S, Hamzeh-Cognasse H, Chavarin P, Genin C, Garraud O and Cognasse F (20070 A flow cytometry technique to study intracellular signals NF-kB and STAT3 in peripheral blood mononuclear cells. BMC Molecular Biology 8 64
Lafuente N, Matesanz N, Azcutia V, Romacho T, Nevado J, Rodriguez-Manas L, Moncada S, Peiro C and Sanchez-Ferrer CF (2008) The deleterious effect of high concentrations of D-glucose requires pro-inflammatory preconditioning. Journal of Hypertension 26 478-485
Laga M, Cottyn A, Van Herreweghe F, Berghe WV, Haegeman G, Van Oostveldt P, Vanderkerckhove J and Vancompernolle K (2007) Methylglyoxal suppresses TNF-alpha-induced NF-kB activation by inhibiting NF-kB DNA-binding. BiochemicalPharmacology 74 579-589
Lagoumintzis G, Xaplanteri P, Dimitracopoulos G and Paliogianni F (2007) TNF-a induction by Pseudomonas aeruginosa lipopolysaccharide or Slime-glycolipoprotein in human monocytes is regulated at the level of mitogen-activated protein kinase activity: a distinct role of Toll-like receptor 2 and 4. Scandinavian Journal of Immunology in press
Lægreid A, Medvedev A, Nonstad U, Bombara MP, Ranges G, Sundan A and Espevik T (1994) Tumor necrosis factor receptor p75 mediates cell-specific activation of nuclear factor kB and induction of human cytomegalovirus. Journal of Biological Chemistry 269 7785-7791
Laflamme N and Rivest S (1999) Effects of systemic immunogenic insults and circulating proinflammatory cytokines on the transcription of the inhibitory factor kBa within specific cellular populations of the rat brain. Journal of Neurochemistry 73 309-321
Laflamme N, Lacroix S and Rivest S (1999) An essential role of interleukin-1beta in mediating NF-kB activity and COX-2 transcription in cells of the blood-brain barrier in response to a systemic and localized inflammation but not during endotoxemia. Journal of Neuroscience 19 10923-10930
Laflamme N, Soucy G and Rivest S (2001) Circulating cell wall components derived from gram-negative, not gram-positive, bacteria cause a profound induction of the gene-encoding Toll-like receptor 2 in the CNS. Journal of Neurochemistry 79 648-657
Lafuente MJ, Martin P, Garcia-Cao I, Diaz-Meco MT, Serrano M and Moscat J (2003) Regulation of mature T lymphocyte proliferation and differentiation by Par-4. EMBO Journal 22 4689-4698
Lagadec P, Griessinger E, Nawrot MP, Fenouille N, Colosetti P, Imbert V, Mari M, Hofman P, Czerucka D, Rousseau D, Berard E, Dreano M and Peyron JF (2008) Pharmacological targeting of NF-kappaB potentiates the effect of the topoisomerase inhibitor CPT-11 on colon cancer cells. British Journal of Cancer in press
Lagarde SM, Ten Kate FJ, Richel DJ, Offerhaus GJ and van Lanschot JJ (2007) Molecular prognostic factors in adenocarcinoma of the esophagus and gastroesophageal junction.
Annals of Surgical Oncology 14 977-991
Lagoumintzis G, Christofidou M, Dimitracopoulos G and Paliogianni F (2003) Pseudomonas aeruginosa slime glycolipoprotein is a potent stimulant of tumor necrosis factor alpha gene expression and activation of transcription activators nuclear factor kB and Activator Protein 1 in human monocytes. Infection & Immunity 71 4614-4622
Lagresle C, Mondière P, Bella C, Krammer PH and Defrance T (1996) Concurrent engagement of CD40 and the antigen receptor protects naive and memory human B cells from APO-1/Fas-mediated apoptosis. Journal of Experimental Medicine 183 1377-1388
Laguillier C, Hbibi AT, Baran-marszak F, Metelev V, Cao A, Bymbalista F, Bogdanov Jr A and Fagard R (2007) Cell death in NF-kB-dependent tumour cell lines as a result of NF-kB trapping by linker-modified hairpin decoy oligonucleotide. FEBS Letters in press
Lagunas VM and Melendez-Zaigla J (2008) Nuclear factor-kB as a resistance factor to platinum-based antineoplasic drugs. Met Based Drugs 2008 576104
Lagunoff M and Carroll PA (2003) Inhibition of apoptosis by the gamma-herpesviruses. International Review of Immunology 22 373-399
Lahat A, Horin SB, Lang A, Fudim E, PIcard O and Chowers Y (2008) Lidocaine down-regulates nuclear factor-kB signalling and inhibits cytokine production and T cell proliferation. Clinical and Experimental Immunology in press
Lahdenpohja N and Hurme M (1998) CD28-mediated activation in CD45RA+ and CD45RO+ T cells: enhanced levels of reactive oxygen intermediates and c-Rel nuclear translocation in CD45RA+ cells. Journal of Leukocyte Biology 63 775-780
Lahdenpohja N, Henttinen T and Hurme M (1996) Activation of the protein kinase A increases the DNA-binding and transcriptional activity of c-Rel in T cells. Scandanavian Journal of Immunology 43 640-645
Laherty CD, Hu HM, Opipari AW, Wang F and Dixit VM (1992) The Epstein-Barr virus LMP-1 gene product induces A20 zinc finger protein expression by activating nuclear factor kB. Journal of Biological Chemistry 267 24157-24160
Laherty CD, Perkins ND and Dixit VM (1993) Human T cell leukemia virus type I Tax and phorbol 12-myristate 13-acetate induce expression of the A20 zinc finger protein by distinct mechanisms involving nuclear factor kB. Journal of Biological Chemistry 268 5032-5039
Lahiri DK (2004) Apolipoprotein e as a target for developing new therapeutics for Alzheimer’s disease based on studies from protein, RNA, and regulatory region of the gene. Journal of Molecular Neuroscience 23 225-234
Lahiri DK, Nall C and Ge YW (1999) Promoter activity of the beta-amyloid precursor protein gene is negatively modulated by an upstream regulatory element. Brain Research Molecular Brain Research 71 32-41
Lahti A, Jalonen U, Kankaanranta H and Moilanen E (2003) c-Jun NH2-terminal kinase inhibitor anthra(1,9-cd)pyrazol-6(2H)-one reduces inducible nitric-oxide synthase expression by destabilizing mRNA in activated macrophages. Molecular Pharmacology 64 308-315
Lahti A, Kankaanranta H and Moilanen E (2002) P38 mitogen-activated protein kinase inhibitor SB203580 has a bi-directional effect on iNOS expression and NO production. European Journal of Pharmacology 454 115-123
Lai C, Jiang X and Li X (2006) Development of luciferase reporter-based cell assays. Assay Drug Development Technologies 4 307-315
Lai CH, Fang SH, Rao YK, Geethanglili M, Tang CH, Lin YJ, Hung CH, Wang WC and Tzeng YM (2008) Inhibition of Helicobacter pylori-induced inflammation in human gastric epithelial AGS cells by Phyllanthus urinaria extracts. Journal of Ethnopharmacology in press
Lai CS, Li S, Chai CY, Lo CY, Ho CT, Wang YJ and Pan MH (2007) Inhibitory effect of citrus 5-hydroxy-3,6,7,8,3′,4′-hexamethoxyflavone on 12-O-tetradecanoylphorbol 13-acetate-induced skin inflammation and tumor promotion in mice. Carcinogenesis in press
Lai J-H and Tan T-H (1994) CD28 signaling causes a sustained down-regulation of IkBa which can be prevented by the immunosuppressant rapamycin. Journal of Biological Chemistry 269 30077-30080
Lai JH, Horvath G, Li Y and Tan TH (1995) Mechanisms of enhanced nuclear translocation of the transcription factors c-Rel and NF-kB by CD28 costimulation in human T lymphocytes. Annals of the New York Academy of Science 766 220-223
Lai J-H, Horvath G, Subleski J, Bruder J, Ghosh P and Tan T-H (1995) RelA is a potent transcriptional activator of the CD28 response element within the interleukin 2 promoter. Molecular and Cellular Biology 15 4260-4271
Lai JL, Zandeck M, Mary JY, Bernandi F, Izydorczyk V, Flatchip M, Morel P, Jovet JP, Bautos F and Facon T (1995) Improved cytogenetics in multiple myeloma: a study of 151 patients including 117 patients at diagnosis. Blood 85 2490-2497
Lai MM (2000) Hepatitis viruses and signal transduction: true to the core? Hepatology 32 427-429
Lai PC, Smith J, Bhangal G, Chaudhry KA, Chaudhry AN, Keith JR JC, Tam FW, Pusey CD and Cook HT (2005) Interleukin-11 reduces renal injury and glomerular NF-kB activity in murine experimental glomerulonephritis. Nephron Exp Nephrol 101 e146-e154
Lai TH, Fong YC, FU WM, Yang RS and Thang CH (2008) Osteoblasts-derived BMP-2 enhances the motility of prostate cancer cells via activation of integrins. Prostate in press
Lai WC, Zhou M, Shankavaram U, Peng G, Wahl LM (2003) Differential regulation of lipopolysaccharide-induced monocyte matrix metalloproteinase (MMP)-1 and MMP-9 by p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases. Journal of Immunology 170 6244-6249
Lai Yl and Yamaguchi M (2007) Phytocomponent p-hydroxycinnamic acid inhibits osteoclast-like cell formation in mouse bone marrow cultures. InternationalJournal of Molecular Medcine 19 123-128
Laín de Lera T, Folgueira L, Martin AG, Dargemont C, Pedraza M-A, Garcia-Matin A, Bermejo M, Bonay P, Fresno M and Alcami J (1999) Expression of IkBa in the nucleus of human peripheral blood T lymphocytes. Oncogene 18 1581-1588
Laine ML, Morre SA, Murillo LS, van Winkelhoff AJ and Pena AS (2005) CD14 and TLR4 gene polymorphisms in adult periodontitis. Journal of Dental Research 84 1042-1046
Laine PS, Schwartz EA, Wang Y, Zhang WY, Karnik SK, Musi N and Reaven PD (2007) Palmitic acid induces IP-10 expression in human macrophages via NF-kB activation. Biochemical and Biophysical Research Communications in press
Laird SM, Tuckerman EM, Cork BA and Li TC (2000) Expression of nuclear factor kB in human endometrium; role in the control of interleukin 6 and leukemia inhibitory factor production. Molecular Human Reproduction 6 34-40
Laitinen S, Fontaine C, Fruchart J and Staels B (2005) The role of the orphan nuclear receptor Rev-Erbalpha in adipocyte differentiation and function. Biochimie 87 21-25
Lajoie-Kadoch S, Joubert P, Letuve S, Halayko AJ, Martin JG, Soussi-Gounni A and Hamid Q (2006) TNFa and IFNg inversely modulate expression of the IL-17E receptor in airway smooth muscle cells. American Journal of Physiology: Lung Cell and Molecular Physiology 290 L1238-L1246
Lake BB, Ford R and Kao KR (2001) Xrel3 is required for head development in Xenopus laevis. Development 128 263-273
Lakhani SR (2004) Putting the brakes on cylindromatosis? New England Journal of Medicine 350 187-188
Lakics V, Medvedev AE, Okada S, Vogel SN (2000) Inhibition of LPS-induced cytokines by Bcl-xL in a murine macrophage cell line. Journal of Immuno1ogy 65 2729-2737
Lakshmanan U and Porter AG (2007) Caspase-4 interacts with TNF receptor-associated factor 6 and mediates lipopolysaccharide-induced NF-kB-dependent production of IL-8 and CC chemokine ligand 4 (Macrophage-Inflammatory Protein-1 ). Journal of Immunology 179 8480-8490
Lakshminarayanan V, Drab-Weiss EA and Roebuck KA (1998) H2O2 and tumor necrosis factor-a induce differential binding of the redox-responsive transcription factors AP-1 and NF-kB to the interleukin-8 promoter in endothelial and epithelial cells. Journal of Biological Chemistry 273 32670-32678
Lal MA, Brismar H, Eklof AC and Aperia A (2002) Role of oxidative stress in advanced glycation end product-induced mesangial cell activation. Kidney International 61 2006-2014
Lallemand F, Mazars A, Prunier C, Bertrand F, Kornprost M, Gallea S, Roman-Roman S, Cherqui G and Atfi A (2001) Smad7 inhibits the survival nuclear factor kB and potentiates apoptosis in epithelial cells. Oncogene 20 879-884
Lallena M-J, Diaz-Meco MT, Bren G, Payá CV and Moscat J (1999) Activation of IkB kinase b by protein kinase C isoforms. Molecular and Cellular Biology 19 2180-2188
Lalli CA, Pauli JR, Prada PO, Cintra DE, Ropelle ER, Velloso LA and Saad MJ (2008) Statin modulates insulin signaling and insulin resistance in liver and muscle of rats fed a high-fat diet. Metabolism 57 57-65
Lalmanach-Girard AC, Chiles TC, Parker DC and Rothstein TL (1993) T cell-dependent induction of NF-kB in B cells. Journal of Experimental Medicine 177 1215-1219
Lalor DJ, Truong B, Henness S, Blake AE, Ge Q, Ammit AJ, Armour CL and Hughes JM (2004) Mechanisms of serum potentiation of GM-CSF production by human airway smooth muscle cells. American Journal of Physiology: Lung Cell and Molecular Physiology 287 L1007-L1016
Lalaor PF, Sun PJ, Weston CJ, Martin-Santos A, Wakelam MJ and Adams DH (2007) Activation of vascular adhesion protein-1 on liver endothelium results in an NF-kB-dependent increase in lymphocyte adhesion. Hepatology 45 465-474
Lalor PF, Tuncer C, Weston C, Martin-Santos A, Smith DJ and Adams DH (2007) Vascular adhesion protein-1 as a potential therapeutic target in liver disease.Annals of the New York Academy of Sciences 1110 485-596
Lam AG, Koppal T, Akama KT, Guo L, Craft JM, Samy B, Schavocky JP, Watterson DM and Van Eldik LJ (2001) Mechanism of glial activation by S100B: involvement of the transcription factor NFkB. Neurobiology of Aging 22 765-772
Lam AP and Dean DA (2008) Cyclic stretch-induced nuclear localization of transcription factors results in increased nuclear targeting of plasmids in alveolar epithelial cells. Journal of Gene Medicine in press
Lam LT, Davis RE, Pierce J, Hepperle M, Xu Y, Hottelet M, Nong Y, Wen D, Adams J, Dang L and Staudt LM (2005) Small molecule inhibitors of IkB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling. Clinical Cancer Research 11 28-40
Lam LT, Wright G, Davis RE, Lenz G, Farinha P, Dang L, Chan JW, Rosenwald A, Gascoyne R and Staudt LM (2007) Cooperative signaling through the STAT3 and NF-kB pathways in subtypes of diffuse large B cell lymphoma. Blood in press
Lam QLK, Zheng B-J, Jin D-Y, Cao X and Lu L (2007) Leptin induces CD40 expression through the activation of AKT in murine dendritic cells. Journal of Biological Chemistry 282 27587-27597
Lamas O, Moreno-Aliaga MJ, Martinez JA and Marti A (2003) NF-kB-binding activity in an animal diet-induced overweightness model and the impact of subsequent energy restriction. Biochemical and Biophysical Research Communications 311 533-539
LaMarco K, Thompson CC, Byers BP, Walton EM and McKnight SL (1991) Identification of Ets- and Notch-related subunits in GA binding protein. Science 253 789-792
Lamb JA, Ventura JJ, Hess P, Flavell RA and Davis RJ (2003) JunD mediates survival signaling by the JNK signal transduction pathway. Molecular Cell 11 1479-1489
Lambeng N, Michel PP, Brugg B, Agid Y and Ruberg M (1999) Mechanisms of apoptosis in PC12 cells irreversibly differentiated with nerve growth factor and cyclic AMP. Brain Research 821 60-68
Lambert C, Li J, Jonscher K, Yang TC, Reigan P, Quintana M, Harvey J and Freed BM (2007) Acrolein inhibits cytokine gene expression by alkylating cysteine and arginine residues in the NF-kB1 DNA-binding domain. Journal Biological Chemistry 282 19666-19675
Lambert C, Oury C, Dejardin E, Chariot A, Piette J, Malaise M, Merville MP and Franchimont N (2007) Further insights in the mechanisms of interleukin-1beta stimulation of osteoprotegerin in osteoblast-like cells. Journal of Bone andMineral Research in press
Lambert JD and Yang CS (2003) Mechanisms of cancer prevention by tea constituents. Journal of Nutrition 133 3262S-3267S
Lambert PF, Ludford-menting MJ, Deacon NJ, Kola I and Doherty RR (1997) The nfkb1 promoter is controlled by proteins of the Ets family. Molecular Biology of the Cell 8 313-323
Lambert S, Yu H, Prchal JT, Lawler J, Ruff P, Speicher D, Cheung MC, Kan YW and Palek J (1990) cDNA sequence for human erythrocyte ankyrin. Proceedings of the National Academy of Sciences USA 87 1730-1734
Lamberti A, Petrella A, Pascale M, Romano MF, Bisogni R, Vita N, Venuta S and Turco MC (2004) Activation of NF-kB/Rel transcription factors in human primary peripheral blood mononuclear cells by interleukin 7. Biology and Chemistry 385 415-417
Lamberti A, Romano MF, Agosti V, Garbi C, Sun SC, Bond HM, Bonelli P, Turco MC and Venuta S (1999) Regulation of cell survival in CD95-induced T cell apoptosis: role of NF-kB/Rel transcription factors. Apoptosis 4 179-186
Lamberti C, Lin KM, Yamamoto Y, Verma U, Verma IM, Byers S and Gaynor RB (2001)Regulation of b-catenin function by the IkB kinases. Journal of Biological Chemistry 276 42276-42286
Lamhamedi-Cherradi SE, Zheng S, Hilliard BA, Xu L, Sun J, Alsheadat S, Liou HC and Chen YH (2003) Transcriptional regulation of type I diabetes by NF-kB. Journal of Immunology 171 4886-4892
Lamkanfi M, Declercq W, Vanden Berghe T and Bendenabeele P (2006) Caspases leave the beaten track: caspase-mediated activation of NF-kB. Journal of Cell Biology 173 165-171
Lamkanfi M, Denecker G, Kalai M, D’hondt K, Meeus A, Declercq W, Saelens X and Vandenabeele P (2004) INCA: a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation. Journal of Biological Chemistry 279 51729-51738
Lamkanfi M, D’hondt K, Vande Walle L, van Gurp M, Denecker G, Demeulemeester J, Kalai M, Declercq W, Saelens X, Vandenabeele P (2005) A novel caspase-2 complex containing TRAF2 and RIP1. Journal of Biological Chemistry 280 6923-6932
Lamkanfi M, Festjens N, Declercq W, Berghe TV and Vandenabeele P (2007) Caspases in cell survival, proliferation and differentiation. Cell Death andDifferentiation 14 44-55
Lamkanfi M, Kalai M, Saelens X, Declercq W and Vandenabeele P (2004) Caspase-1 activates NF-kB independent of its enzymatic activity. Journal of Biological Chemistry 279 24785-24793
Lammerding J, Schulze PC, Takahashi T, Kozlov S, Sullivan T, Kamm RD, Stewart CL and Lee RT (2004) Lamin A/C deficiency causes defective nuclear mechanics and mechanotransduction. Journal of Clinical Investigation 113 370-378
LaMonica R, Kocer SS, Nazarova J, Dowling W, Geimonen E, Shaw RD and Mackow ER (2001) VP4 differentially regulates TRAF2 signaling, disengaging JNK activation while directing NF-kB to effect rotavirus specific cellular responses. Journal of Biological Chemistry 276 19889-19896
Lamothe B, Besse A, Campos AD, Webster Wk, Wu H and Darnay BG (2007) Site-specific Lys-63-linked TRAF6 auto-ubiquitination is a critical determinantof IKK activation. Journal of Biological Chemistry 282 4102-4112
Lamothe B, Campos AD, Webster WK, Gopinathan A, Hur L and Darnay BG (2008) The RING domain and first Zinc-finger of TRAF6 coordinate signaling by IL-1, LPS, and RANKL. Journal of Biological Chemistry in press
Lamothe B, Webster WK, Gopinathan A, Besse A, Campos AD and Darnay BG (2007) TRAF6 ubiquitin ligase is essential for RANKL signaling and osteoclast differentiation. Biochemical and Biophysical Research Communications in press
Lampronti I, Bianchi N, Borgatti M, Fabbri E, Vizziello L, Khan MT, Ather A, Brezena D, Tahir MM and Gambari R (2005) Effects of vanadium complexes on cell growth of human leukemia cells and protein-DNA interactions. Oncology Reports 14 9-15
Lampronti I, Khan MT, Bianchi N, Ather A, Borgatti M, Vizziello L, Fabbri E and Gambari R (2006) Bangladeshi medicinal plant extracts inhibiting molecular interactions between nuclear factors and target DNA sequences mimicking NF-kB binding sites.
Medicinal Chemistry 1 327-333
Lamsoul I, Lodewick J, Lebrun S, Brasseur R, Burny A, Gaynor RB and Bex F (2005) Exclusive ubiquitination and sumoylation on overlapping lysine residues mediate NF-kB activation by the human T-cell leukemia virus Tax oncoprotein. Molecular and Cellular Biology 25 10391-10406
Lan CC, Yu HS, Wu CS, Kuo HY, Chai CY and Chen GS (2005) FK506 inhibits tumour necrosis factor-alpha secretion in human keratinocytes via regulation of nuclear factor-kB. British Journal of Dermatology 153 725-732
Lan KP, Wang CJ, Hsu JD, Chen KM, Lai SC and Lee HH (2004) Induced eosinophilia and proliferation in Angiostrongylus cantonensis-infected mouse brain are associated with the induction of JAK/STAT1, IAP/NF-kB and MEKK1/JNK signals. Journal of Helminthology 78 311-317
Lan L, Zhao F, Wang Y and Zeng H (2006) The mechanism of apoptosis induced by a novel thioredoxin reductase inhibitor in A549 cells: Possible involvement of nuclear factor-kB-dependent pathway. European Journal of Pharmacology in press
Lan Y, Zhou Q and Wu ZL (2004) NF-kB involved in transcription enhancement of TGF-beta1 induced by Ox-LDL in rat mesangial cells. Chinese Medical Journal (English) 117 225-230
Lance RC and Hays AM (2006) The autocrine TNFalpha signalling loop in keratinocytes requires atypical PKC species and NF-kB activation but is independent of cholesterol-enriched membrane microdomains. BiochemicalPharmacology in press
Land SC and Wilson SM (2005) Redox regulation of lung development and perinatal lung epithelial function. Antioxidant and Redox Signaling 7 92-107
Land WG, Gutmann T and Daar AS (2008) Emerging science, emerging ethical issues: who should fund innate alloimmunity-suppressing drugs? Acta Chir Belg 108 73-82
Landesman-Bollag E, Romieu-Mourez R, Song DH, Sonenshein GE, Cardiff RD and Seldin DC (2001) Protein kinase CK2 in mammary gland tumorigenesis. Oncogene 20 3247-3257
Landi S, Moreno V, Gioia-Patricola L, Guino E, Navarro M, de Oca J, Capella G, Canzian F; Bellvitge Colorectal Cancer Study Group (2003) Association of common polymorphisms in inflammatory genes interleukin (IL)6, IL8, tumor necrosis factor alpha, NFKB1, and peroxisome proliferator-activated receptor gamma with colorectal cancer. Cancer Research 63 3560-3566
Landowski TH, Olashaw NE, Agrawal D and Dalton WS (2003) Cell adhesion-mediated drug resistance (CAM-DR) is associated with activation of NF-kB (RelB/p50) in myeloma cells. Oncogene 22 2417-2421
Landsvater RM, de Wit MJ, Peterson LF, Sinke RJ, van Kessel AG, Lips CJM and Höppener JWM (1997) Exclusion of the Nuclear Factor-kB3 (RELA) gene as candidate for the multiple endocrine neoplasia type 1 (MEN 1) gene. Biochemical and Molecular Medicine 60 76-79
Lang A, Lahav M, Sakhnini E, Barshack I, Fidder HH, Avidan B, Bardan E, Hershkoviz R, Bar-Meir S and Chowers Y (2004) Allicin inhibits spontaneous and TNF-alpha induced secretion of proinflammatory cytokines and chemokines from intestinal epithelial cells. Clinical Nutrition 23 1199-1208
Lang CH, Nystrom GJ and Frost RA (1999) Regulation of IGF binding protein-1 in hep G2 cells by cytokines and reactive oxygen species. American Journal of Physiology 276 G719-G727
Lang F, Bohmer C, Palmada M, Seebohm G, Strutz-Seebohm N and Vallon V (2006) Pathophysiological signifcance of the serum-and glucocotricoid-inducible kinase isoforms. Physiological Reviews 86 1151-1178
Lang H, Schulte BA and Schmiedt RA (2005) Ouabain induces apoptotic cell death in type I spiral ganglion neurons, but not type II neurons. Journal of the Association for Research in Otolaryngology 6 63-71
Lang H, Schulte BA, Zhou D, Smythe N, Spicer SS and Schmiedt RA (2006) Nuclear factor kB deficiency is associated with auditory nerve degeneration and increased noise-induced hearing loss. Journal of Neuroscience 26 3541-3550
Lang KS, Weigert C, Braedel S, Fillon S, Palmada M, Schleicher E, Rammensee HG and Lang F (2003) Inhibition of interferon-gamma expression by osmotic shrinkage of peripheral blood lymphocytes. American Journal of Physiology: Cell Physiology 284 C200-C208
Lang MF, Schneider A, Kruger C, Schmid R, Dziarski R and Schwaninger M (2007) Peptidoglycan recognition protein-S (PGRP-S) is upregulated by NF-kB. Neuroscience Letters in press
Lang V, Janzen J, Fischer GZ, Soneji Y, Beinke S, Salmeron A, Allen H, Hay RT, Ben-Neriah Y and Ley SC (2003) betaTrCP-mediated proteolysis of NF-kB1 p105 requires phosphorylation of p105 serines 927 and 932. Molecular and Cellular Biology 23 402-413
Lang V, Symons A, Watton SJ, Janzen J, Soneji Y, Beinke S, Howell S and Ley SC (2004) ABIN-2 forms a ternary complex with TPL-2 and NF-kB1 p105 and is essential for TPL-2 protein stability. Molecular and Cellular Biology 24 5235-5248
Lang-Lazdunski L, Blondeau N, Jarretou G, Lazdunski M and Heurteaux C (2003) Linolenic acid prevents neuronal cell death and paraplegia after transient spinal cord ischemia in rats. Journal of Vascular Surgery 38 564-575
Langat DK, Morales PJ, Omwandho CO and Fazleabas At (2007) Polymorphisms in the Paan-AG promoter influence NF-kB binding and transcriptional activity.Immunogenetics in press
Langen RC, Schols AM, Kelders MC, Wouters EF and Janssen-Heininger YM (2001) Inflammatory cytokines inhibit myogenic differentiation through activation of nuclear factor-kB. FASEB Journal 15 1169-1180
Langen RC, Van Der Velden JL, Schols AM, Kelders MC, Wouters EF and Janssen-Heininger YM (2004) Tumor necrosis factor-alpha inhibits myogenic differentiation through MyoD protein destabilization. FASEB Journal 18 227-237
Langouche L, Vanhorebeek I, Vlasselaers D, Vander Perre S, Wouters PH, Skogstrand K, Hansen TK and Van den Berghe G (2005) Intensive insulin therapy protects the endothelium of critically ill patients. Journal of Clinical Investigation 115 2277-2286
Laniado-Schwartzman M, Lavrovsky Y, Stoltz RA, Conners MS, Falck JR, Chauhan K and Abraham NG (1994) Activation of nuclear factor kB and oncogene expression by 12(R)-hydoxyeicosatrienoic acid, an angiogenic factor in microvessel endothelial cells. Journal of Biological Chemistry 269 24321-24327
Lanoix J, Lacoste J, Pepin N, Rice N and Hiscott J (1994) Overproduction of NFKB2 (lyt-10) and c-Rel: a mechanism for HTLV-I Tax-mediated trans-activation via the NF-kB signalling pathway. Oncogene 9 841-852
Lantner F, Starlets D, Gore Y, Slaishon L, Yamit-Hezi A, Dikstein R, Leng L, Bucala R, Machluf Y, Oren M and Schachar I (2007) CD74 induces TAp63 expression leading to B cell survival. Blood in press
Lanza L, Scudeletti M, Monaco E, Monetti M, Puppo F, Filaci G and Indiveri F (1999) Possible differences in the mechanism(s) of action of different glucocorticoid hormone compounds. Annals of the New York Academy of Sciences 876 193-197
Lao Q, Fukamachi T, Saito H, Kuge O, Nishijima M and Kobayashi H (2006) Requirement of an IkB-beta COOH terminal region protein for acidic-adaptation in CHO cells. Journal of Cellular Physiology 207 238-243
Lao Q, Kuge O, Fukamachi T, Kakegawa T, Saito H, Nishijima M and Kobayashi H (2004) An IkB-b COOH terminal region protein is essential for the proliferation of CHO cells under acidic stress. Journal of Cell Physiology 203 186-192
Laos S, Baeckstrom D and Hansson GC (2006) Inhibition of NF-kB activation and chemokine expression by the leukocyte glycoprotein, CD43, in colon cancer cells.International Journal of Oncology 28 695-704
Lapointe R, Lemieux R and Darveau A (1996) HIV-1 LTR activity in human CD40-activated B lymphocytes is dependent on NF-kB. Biochemical and Biophysical Research Communications 229 959-964
Lapouge G, Marcias G, Erdmann E, Kessler P, Cruchant M, Serra S, Bergerat JP and Ceraline J (2008) Specific properties of a C-terminal truncated androgen receptor detected in hormone refractory prostate cancer. Advances in Experimental Medicine and Biology 617 529-534
Lappanen T, Jalonen U, Kankaanranta H, Tuominen R, and Moilanen E (2008) Inhibition of protein kinase C betaII downregulates tristetraprolin expression in activated macrophages. Inflammation Research 57 230-240
Lappas M, Permezel M and Rice GE (2003) N-acetyl-cysteine inhibits phospholipid metabolism, proinflammatory cytokine release, protease activity, and nuclear factor-kB deoxyribonucleic acid-binding activity in human fetal membranes in vitro. Journal of Clinical Endocrinology and Metabolism 88 1723-1729
Lappas M, Permezel M, Georgiou HM and Rice GE (2002) Nuclear factor kB regulation of proinflammatory cytokines in human gestational tissues in vitro. Biol Reprod 67 668-673
Lappas M, Permezel M, Georgiou HM and Rice GE (2004) Regulation of phospholipase isozymes by nuclear factor-kB in human gestational tissues in vitro. Journal of Clinical Endocrinology and Metabolism 89 2365-2372
Lappas M, Permezel M, Ho PW, Moseley JM, Wlodek ME and Rice GE (2004) Effect of nuclear factor-kB inhibitors and peroxisome proliferator-activated receptor-gamma ligands on PTHrP release from human fetal membranes. Placenta 25 899-704
Lappas M, Permezel M, Holdsworth SJ, Zanoni G, Porta A and Rice GE (2007) Antiinflammatory effects of the cyclopentenone isoprostane 15-A(2)-IsoP in human gestational tissues.
Free Radical Biology and Medicine 42 1791-1796
Lappas M, Permezel M and Rice GE (2005) Leptin and adiponectin stimulate the release of pro-inflammatory cytokines and prostaglandins from human placenta and maternal adipose tissue via NF-kB, PPAR-gamma and ERK 1/2. Endocrinology 146 3334-3342
Lappas M, Permezel M and Rice GE (2006) 15-deoxy-delta(12,14)-prostaglandin J(2) and troglitazone regulation of the release of phospholipid metabolites, inflammatory cytokines and proteases from human gestational tissues. Placenta in press
Lappas M, Permezel M and Rice GE (20067) Advanced glycation endproducts mediate pro-inflammatory actions in human gestational tissues via nuclear factor-kB and extracellular signal-regulated kinase 1/2. Journal of Endocrinology 193 269-277
Lappas M and Rice GE (2004) Phospholipase A(2) isozymes in pregnancy and parturition. Prostaglandins Leukot Essent Fatty Acids 70 87-100
Lappas M and Rice GE (2006) The role and regulation of the nuclear factor kB signalling pathway in human labour. Placenta in press
Lappas M, Yee K, Permezel M and Rice GE (2004) Sulphasalazine and BAY 11-7082 interfere with the NF-kB and IKK-b pathway to regulate the release of pro-inflammatory cytokines from human adipose tissue and skeletal muscle, in vitro. Endocrinology 146 1491-1497
Lappas M, Yee K, Permezel M and Rice GE (2005) Lipopolysaccharide and TNF-a activate the nuclear factor kB pathway in the human placental JEG-3 cells. Placenta 186 457-465
Lapteva N, Ide K, Nieda M, Ando Y, Hatta-Ohashi Y, Minami M, Dymshits G, Egawa K, Juji T and Tokunaga K (2002) Activation and suppression of renin-angiotensin system in human dendritic cells. Biochemical and Biophysical Research Communications 296 194-200
Lara Jr PN, Bold RJ, Mack PC, Davies AM, Gumerlock PH and Gandara DR (2005) Proteasome inhibition in small-cell lung cancer: preclinical rationale and clinical applications. Clinical Lung Cancer 7 S67-S71
Lara Jr PN, Davies AM, Mack PC, Mortenson MM, Bold RJ, Gumerlock PH and Gandara DR (2004) Proteasome inhibition with PS-341 (bortezomib) in lung cancer therapy. Seminars in Oncology 31 40-46
Larabee JL, Hocker JR, Lerner MR, Lightfoot SA, Cheung JY, Brackett DJ, Gallucci Rm and Hanas JS (2005) Stress induced in heart and other tissues by rat dermal exposure to JP-8 fuel.
Cell Biology and Toxicolology 21 233-246
Larabi M, Legrand P, Appel M, Gil S, Lepoivre M, Devissaguet J, Puisieux F and Barratt G (2001) Reduction of no synthase expression and tumor necrosis factor alpha production in macrophages by amphotericin B lipid carriers. Antimicrobial Agents and Chemotherapy 45 553-562
Largo R, Alvarez-Soria MA, Diez-Ortego I, Calvo E, Sanchez-Pernaute O, Egido J and Herrero-Beaumont G (2003) Glucosamine inhibits IL-1beta-induced NFkB activation in human osteoarthritic chondrocytes. Osteoarthritis Cartilage 11 290-298
Larmonier N, Cantrell J, Lacasse C, Li G, Janikashvili N, Situ E, Sepassi M, Andreansky S and Katsanis E (2008) Chaperone-rich tumor cell lysate-mediated activation of antigen-presenting cells resists regulatory T cell suppression. Journal of Leukocyte Biology in press
Larmonier N, Marron M, Zeng Y, Cantrell J, Romanoski A, Sepassi M, Thompson S, Chen X, Andreansky S and Katsanis E (2007) Tumor-derived CD4(+)CD25 (+) regulatory T cell suppression of dendritic cell function involves TGF-beta and IL-10. Cancer Immunology and Immunotherapy 56 48-59
Larmonier N, Merino D, Nicolas A, Cathelin D, Besson A, Bateman A, Solary E, Martin F,Katsanis E and Bonnotte B (2006) Apoptotic, necrotic, or fused tumor cells: An equivalent source of antigen for dendritic cell loading. Apoptosis in press
Larose RN and Svoian M (1965) Avian lymphomatosis. IX. Mortality and seriological response of chickens of various ages to graded doses of T-strain. Avian Diseases 9 604-610
Larousserie F, Bardel E, Coulomb L’hermine A, Canioni D, Brousse N, Kastelein R and Dvergne O (2006) Variable expression of Epstein-Barr virus-induced gene 3 during normal B-cell differentiation and among B-cell lymphomas. Journal ofPathology in press
Larousserie F, Bardel E, Pflanz S, Arnulf B, Lome-Maldonado C, Hermine O, Bregeaud L, Perennec M, Brousse N, Kastelein R and Devergne O (2005) Analysis of Interleukin-27 (EBI3/p28) expression in Epstein-Barr Virus- and Human T-Cell Leukemia Virus Type 1-associated lymphomas: heterogeneous expression of EBI3 subunit by tumoral cells. American Journal of Pathology 16 1217-1228
Laroux FS, Pavlick KP, Hines IN, Kawachi S, Harada H, Bharwani S, Hoffman JM and Grisham MB (2001) Role of nitric oxide in inflammation. Acta Physiologica Scandinavica 173 113-118
Larregina AT, Morelli AE, Tkacheva O, Erdos G, Donahue C, Watkins SC, Thomson AW and Falo LD (2003) Highly efficient expression of transgenic proteins by naked DNA transfected dendritic cells through terminal differentiation. Blood 103 811-819
Larsen AK, Seternes OM, Larsen M, Aasmoe L and Bang B (2008) Salmon trypsin stimulates the expression of interleukin-8 via protease-activated receptor-2. Toxicology and Applied Pharmacology in press
Larsen L, Storling J, Darville M, Eizirik DL, Bonny C, Billestrup N and Mandrup-Poulsen T (2005) Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor kB-mediated gene expression in insulin-producing INS-1E cells. Diabetologia 48 2582-2590
Larsen M, Tazzyman S, Lund EL, Junker N, Lewis CE, Kristjansen PE and Murdoch C (2008) Hypoxia-induced secretion of macrophage migration-inhibitory factor from MCF-7 breast cancer cells is regulated in a hypoxia-inducible factor-independent manner. Cancer Letters in press
Larson CJ, Li YW, Mercurio F and Muller R (1999) Functional characterization of a purified, recombinant NF-kB/IkB complex. Biochemical and Biophysical Research Communications 260 691-698
Larsson P, Claesson HE and Kennedy BP (1998) Multiple splice variants of the human calcium-independent phospholipase A2 and their effect on enzyme activity. Journal of Biological Chemistry 273 207-214
Larsson P, Ollinger K and Rosdahl I (2006) Ultraviolet (UV) A- and UVB-induced redox alterations and activation of nuclear factor-kB in human melanocytes-protective effects of alpha-tocopherol. British Journal of Dermatology 155 292-300
Larsson P, Ulfhammer E, Karlsson L, Bokarewa M, Wahlander K and Jern S (2008) Effects of IL-1beta and IL-6 on tissue-type plasminogen activator expression in vascular endothelial cells. Thrombosis Research in press
Larter CZ, Yeh MM< Cheng J, Williams J, Brown S, Dela Pena A, Bell-Anderson KS and Farrell GC (2007) Activation of peroxisome proliferator-activated receptor alpha by dietary fish oil attenuates steatosis, but does not prevent experimental steatohepatitis because of hepatic lipoperoxide accumulation.
Journal of Gastroenterology and Hepatology in press
Lasala C, Carre-Eusebe D, Picard JY and Rey R (2004) Subcellular and molecular mechanisms regulating anti-Mullerian hormone gene expression in mammalian and nonmammalian species. DNA Cell Biology 23 572-575
Lasarte JJ, Sarobe P, Boya P, Casares N, Arribillaga L, De Cerio AL, Gorraiz M, Borras-Cuesta F and Prieto J (2003) A recombinant adenovirus encoding hepatitis C virus core and E1 proteins protects mice against cytokine-induced liver damage. Hepatology 37 461-470
Laschke MW, Schwender C, Scheuer C, Vollmar B and Menger MD (2007) Dietary glycine does not affect physiological angiogenesis and reproductive function, but inhibits apoptosis in endometrial and ovarian tissue by down-regulation of nuclear factor-kB. Fertility and Sterility in press
Lasek W, Switaj T, Sienko J, Kasprzycka M, Basak G, Miklaszewicz P, Maj M, Nowis D, Grzela T, Golab J, Mlynarczuk I, Jalili A, Kaminska B, Dziembowska M, Czajkowski K, Nowaczyk M, Gorska A and Kazimierczuk Z (2002) Stimulation of TNF-a production by 2-(1-adamantylamino)-6-methylpyridine (AdAMP) – a novel immunomodulator with potential application in tumour immunotherapy. Cancer Chemotherapy and Pharmacology 50 213-222
Lash LH, Putt DA, Hueni SE and Horwitz BP (2005) Molecular markers of trichloroethylene-induced toxicity in human kidney cells. Toxicology and Applied Pharmacology 206 157-168
Lashmit PE, Lundquist CA, Meier JL and Stinski MF (2004) Cellular repressor inhibits human cytomegalovirus transcription from the UL127 promoter. Journal of Virology 78 5113-5123
Laska MJ, Strandbygard D, Kjeldgaard A, Mains M, Corydon TJ, Memon AA, Sorensen BS, Vogel U, Jensen UB and Nexo BA (2007) Expression of the RAI gene is conducive to apoptosis: Studies of induction and interference. Experimental Cell Research in press
Laskin DL, Fakhrzadeh L, Heck DE, Gerecke D and Laskin JD (2002) Upregulation of phosphoinositide 3-kinase and protein kinase B in alveolar macrophages following ozone inhalation. role of NF-kB and STAT-1 in ozone-induced nitric oxide production and toxicity. Molecular and Cellular Biochemistry 234-235 91-98
Laskov R, Berger N and Horwitz MS (2005) Differential effects of tumor necrosis factor-alpha and CD40L on NF-kB inhibitory proteins IkappaBalpha, beta and varepsilon and on the induction of the Jun amino-terminal kinase pathway in Ramos Burkitt lymphoma cells. European Cytokine Network 16 267-276
Lass C, Vocanson M, Wagner S, Schempp CM, Nicolas JF, Merfort I and Martin SF (2008) Anti-inflammatory and immune-regulatory mechanisms prevent contact hypersensitivity to Arnica montana L. Experimental Dermatology in press
Lassila O, Vainio O, Toivanen P and Melchers F (1991) Doing the B-cell rag. New Biologist 3 1155-1160
Last JA, Gohil K, Mathrani VC and Kenyon NJ (2005) Systemic responses to inhaled ozone in mice: cachexia and down-regulation of liver xenobiotic metabolizing genes. Toxicology and Applied Pharmacology 208 117-126
Lasunskaia EB, Campos MN, de Andreade MR, Dammata RA, Kipnis TL, Einicker-Lamas M and Da Silva WD (2006) Mycobacteria directly induce cytoskeletal rearrangements for macrophage spreading and polarization through TLR2-dependent PI3K signaling. Journal of Leukocyte Biology 80 1480-1490
Laszlo CF and Wu S (2008) Mechanism of UV-induced IkBa-independent activation of NF-kB. Photochemistry & Photobiology in press
Latchumanan VK, Singh B, Sharma P and Natarajan K (2002) Mycobacterium tuberculosis antigens induce the differentiation of dendritic cells from bone marrow. Journal of Immunology 169 6856-6564
Latimer M, Ernst MK, Dunn LL, Drutskaya M and Rice NR (1998) The N-terminal domain of IkBa masks the nuclear localization signal(s) of p50 and c-Rel homodimers. Molecular and Cellular Biology 18 2640-2649
Latta M, Kunstle G, Lucas R, Hentze HM and Wendel A (2007) ATP-depleting carbohydrates prevent tumor necrosis factor receptor 1-dependent apoptotic and necrotic liver injury in mice. Journal of Pharmacology and ExperimentalTherapeutics in press
Lattion A-L, Espel E, Reichenbach P, Fromental C, Bucher P, Israël A, Baeuerle P, Rice NR and Nabholz M (1992) Characterization of a new tissue-specific transcription factor binding to the simian virus 40 enhancer TC-II (NF-kB) element. Molecular and Cellular Biology 12 5217-5227
Latzer J,Papoian GA, Prentiss MC, Kmovies EA and Wolynes PG (2006) Induced fit, folding, and recognition of the NF-kB-nuclear localization signals by IkBa and IkBb. Journal of Molecular Biology in press
Lau GW, Goumnerov BC, Walendziewicz CL, Hewitson J, Xiao W, Mahajan-Miklos S, Tompkins RG, Perkins LA and Rahme LG (2003) The Drosophila melanogaster Toll pathway participates in resistance to infection by the gram-negative human pathogen Pseudomonas aeruginosa. Infection and Immunity 71 4059-4066
Lau PP, Li L, Merched AJ, Zhang AL, Ko KW and Chan L (2005) Nicotine induces proinflammatory responses in macrophages and the aorta leading to acceleration of atherosclerosis in low-density lipoprotein receptor-/- mice.Arteriosclerosis, Thrombosis, and Vascular Biology 26 143-149
Lauder A, Castellanos A and Weston K (2001) c-Myb transcription is activated by protein kinase B (PKB) following interleukin 2 stimulation of T cells and is required for PKB-mediated protection from apoptosis. Molecular and Cellular Biology 21 5797-5805
Lauder SN, Carty SM, Carpenter CE, Hill RJ, Talamas F, Bondeson J, Brennan P and Williams AS (2007) Interleukin-1beta induced activation of nuclear factor-kb can be inhibited by novel pharmacological agents in osteoarthritis. Rheumatology (Oxford) in press
Laughlin TM, Bethea JR, Yezierski RP and Wilcox GL (2000) Cytokine involvement in dynorphin-induced allodynia. Pain 84 159-167
Laura M, Mazzeo A, Aguennouz M, Santoro M, Catania MA, Migliorato A, Calapai G and Vita G (2006) Immunolocalization and activation of nuclear factor-kB in the sciatic nerves of rats with experimental autoimmune neuritis. Journal ofNeuroimmunology 174 32-38
Laurencikiene J, van Harmelen V, Arvidsson Nordstrom E, Dicker A, Blomqvist L, Naslund E, Langin D, Arner P and Ryden M (2007) NF-kB is important for TNF-a-induced lipolysis in human adipocytes. Journal of Lipid Research in press
Laurent S, Otsuka M, De Saeger C, Maiter D, Lambotte L and Horsmans Y (2001) Expression of presumed specific early and late factors associated with liver regeneration in different rat surgical models. Lab Invest 81 1299-1307
Laurent S, Starkel P, Leclercq IA, Lambotte L, Maiter D and Horsmans Y (2005) Molecular events associated with accelerated proliferative response in rat livers when partial hepatectomy is preceded by a sham operation. European Journal of Clinical Investigation 35 140-147
Lauret C (2003) Medicinal Chemistry–First Anglo-Swedish Symposium. 23-26 March, 2003, Are Fjallby, Sweden. IDrugs 6 426-428
Laurent S, Horsmans Y, Starkel P, Leclercq I, Sempoux C and Lambotte L (2005) Disrupted NF-kB activation after partial hepatectomy does not impair hepatocyte proliferation in rats.
World Journal of Gastroenterology 11 7345-7350
Laurent-Puig P and Taieb J (2008) Lessons from Tarceva in pancreatic cancer: where are we now, and how should future trials be designed in pancreatic cancer? Current Opinions in Oncology 20 454-458
Laurin N, Brown JP, Morissette J and Raymond V (2002) Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget Disease of bone. American Journal of Human Genetics 70 1582-1588
Lauzurica P, Martinez-Martinez S, Marazuela M, Gomez del Arco P, Martinez C, Sanchez-Madrid F and Redondo JM (1999) Pyrrolidine dithiocarbamate protects mice from lethal shock induced by LPS or TNF-a. European Journal of Immunology 26 1890-1900
Lavagna C, Burgaud JL, Del Soldato P and Rampal P (2001) Antiproliferative effects of nitrosulindac on human colon adenocarcinoma cell lines. Biochemical and Biophysical Research Communications 284 808-816
Lavagno L, Gunella G, Bardelli C, Spina S, Fresu LG, Viano I and Brunelleschi S (2004) Anti-inflammatory drugs and tumor necrosis factor-alpha production from monocytes: role of transcription factor NF-kB and implication for rheumatoid arthritis therapy. European Journal of Pharmacology 501 199-208
Laval SH and Bushby KM (2004) Limb-girdle muscular dystrophies – from genetics to molecular pathology. Neuropathology and Applied Neurobiology 30 91-105
Lavallie ER, Chockalingam PS, Collins-Racie LA, Freeman BA, Keohan CC, Leitges M, Dorner AJ, Morris EA, Majumdar MK and Arai M (2006) Protein kinase C zeta zeta is upregulated in osteoarthritic cartilage and is required for activation of NF-kB by TNF and IL-1 in articular chondrocytes. Journal of BiologicalChemistry 281 24124-24137
Lavie J, Dandre F, Louis H, Lamaziere JM and Bonnet J (1999) Vascular cell adhesion molecule-1 gene expression during human smooth muscle cell differentiation is independent of NF-kB activation. Journal of Biological Chemistry 274 2308-2314
Lavie L (2003) Obstructive sleep apnoea syndrome – an oxidative stress disorder. Sleep Med Rev 7 35-51
Lavon I, Fuchs Zrihan D, Efroni G, Zelikovitch B, Fellig Y and Siegal T (2007) Novel mechanism whereby nuclear factor kB mediates DNA damage repair through regulation of O6-methylguanine-DNA-methyltransferase. Cancer Research 67 8952-8959
Lavon I, Goldberg I, Amit S, Landsman L, Jung S, Tsuberi BZ, Barshack I, Kopolovic J, Galun E, Bujard H and Ben-Neriah Y (2000) High susceptibility to bacterial infection, but no liver dysfunction, in mice compromised for hepatocyte NF-kB activation. Nature Medicine 6 573-577
Lavon I, Pikarsky E, Gutkovich E, Goldberg I, Bar J, Oren M and Ben-Neriah Y (2003) Nuclear factor-kB protects the liver against genotoxic stress and functions independently of p53. Cancer Research 63 25-30
Law AH, Lee Dc, Cheung BK, Yim HC and Lau AS (2006) A role for the non-structural protein-1 of SARS-Coronavirus in chemokine dysregulation. Journal ofVirology in press
Law RE, Stimmel JB, Damore MA, Carter C, Clarke S and Wall R (1992) Lipopolysaccharide-induced NF-kB activation in mouse 70Z/3 pre-B lymphocytes is inhibited by mevinolin and 5′-methylthioadenosine: roles of protein isoprenylation and carboxyl methylation reactions. Molecular and Cellular Biology 12 103-111
Lawless MW, Greene CM, Mulgrew A, Taggart CC, O’Neill SJ and McElvaney NG (2004) Activation of endoplasmic reticulum-specific stress responses associated with the conformational disease Z alpha1-antitrypsin deficiency. Journal of Immunology 172 5722-5726
Lawlor KE, Campbell IK, O’Donnell K, Wu L and Wicks IP (2001) Molecular and cellular mediators of interleukin-1-dependent acute inflammatory arthritis. Arthritis & Rheumatism 44 442-450
Lawrance IC, Wu F, Leite AZ, Willis J, West GA, Fiocchi C and Chakravarti S (2003) A murine model of chronic inflammation-induced intestinal fibrosis down-regulated by antisense NF-kB. Gastroenterology 125 1750-1761
Lawrence CP, Kadioglu A, Yang AL, Coward WR and Chow SC (2006) The cathepsin B inhibitor, z-FA-FMK, inhibits human T cell proliferation in vitro and modulates host response to Pneumococcal infection in vivo. Journal of Immunology 177 3827-3836
Lawrence DM, Seth P, Durham L, Diaz F, Boursiquot R, Ransohoff RM and Major EO (2006) Astrocyte differentiation selectively upregulates CCL2/monocyte chemoattractant protein-1 in cultured human brain-derived progenitor cells. Glia 53 81-91
Lawrence DM, Singh RS, Franklin DP, Carey DJ and Elmore JR (2004) Rapamycin suppresses experimental aortic aneurysm growth. Journal of Vascular Surgery 40 334-338
Lawrence R, Chang L-J, Siebenlist U, Bressler P and Sonenshein GE (1994) Vascular smooth muscle cells express a constitutive NF-kB-like activity. Journal of Biological Chemistry 269 28913-28918
Lawrence T (2002) Modulation of inflammation in vivo through induction of the heat shock response, effects on NF-kB activation. Inflammation Research 51 108-109
Lawrence T and Bebien M (2007) IKKa in the regulation of inflammation and adaptive immunity. Biochemcal Socoety Transactions 35 270-272
Lawrence T, Bebien M, Liu GY, Nizet V and Karin M (2005) IKKa limits macrophage NF-kB activation and contributes to the resolution of inflammation. Nature 434 1138-1143
Lawrence T, Gilroy DW, Colville-Nash PR and Willoughby DA (2001) Possible new role for NF-kB in the resolution of inflammation. Nature Medicine 7 1291-1297
Lawrence T, Puel A, Reichenbach J, Ku CL, Chapgier A, Renner E, Minard-Colin V, Ouachee M and Casanova JL (2005) Autosomal-dominant primary immunodeficiencies. Current Opinion in Hematology 12 22-30
Lawson BR, Manenkova Y, Ahamed J, Chen X, Zou JP, Baccala R, Theofilopoulos AN and Yuan C (2007) Inhibition of transmethylation down-regulates CD4 T cell activation and curtails development of autoimmunity in a model system. Journal of Immunology 178 5366-5274
Lawson C, Ainsworth M, Yacoub M and Rose M (1999) Ligation of ICAM-1 on endothelial cells leads to expression of VCAM-1 via a nuclear factor-kB-independent mechanism. Journal of Immunology 162 2990-2996
Laxmanan S, Datta D, Geehan C, Briscoe DM, and Pal S (2005) CD40: a mediator of pro- and anti-inflammatory signals in renal tubular epithelial cells. Journal of the American Society of Nephrology 16 2714-2723
Lay JD, Hong CC, Huang JS, Yang YY, Pao CY, Lin CH, Lai YP, Lai GM, Cheng AL, Su IJ and Chuang SE (2007) Sulfasalazine suppresses drug resistance and invasiveness of lung adenocarcinoma cells expressing AXL. Cancer Research 673878-3887
Laye S, Lundkvist J and Bartfai T (1998) Human/mouse interleukin-1 receptor/receptor accessory protein interactions in IL-1beta-induced NFkB activation. FEBS Letters 429 307-311
Layfield R (2007) The molecular pathogenesis of Paget disease of bone. Expert Reviews in Molecular Medcine 9 1-13
Layfield R, Cavey MR, Najat D, Long J, Sheppard PW, Ralston SH and Searle MS (2006) p62 mutations, ubiquitin recognition and Paget’s disease of bone.Biochemical Society Transactiions 34 735-737
Layfield R and Searle MS (2008) Disruption of ubiquitin-mediated processes in diseases of the brain and bone. Biochemical Society Transactions 36 469-471
Layfield R and Shaw B (2007) Ubiquitin-mediated signalling and Paget’s disease of bone. BMC Biochemistry 8 S5
Laza-Stanca V, Stanciu LA, Message SD, Edwards MR, Gern JE and Johnston SL (2006) Rhinovirus replication in human macrophages induces NF-kB-dependent tumor necrosis factor alpha production. Journal of Virology 80 8248-8258
Lazaar AL, Amrani Y, Hsu J, Panettieri Jr RA, Fanslow WC, Albelda SM and Pure E (1998) CD40-mediated signal transduction in human airway smooth muscle. Journal of Immunology 161 3120-3127
Lazarov M, Green CL, Zhang JY, Kubo Y, Dajee M and Khavari PA (2003) Escaping G(1) Restraints on neoplasia: Cdk4 regulation by Ras and NF-kB. Cell Cycle 2 79-80
Lazzerini PE, Lorenzini S, Selvi E, Capecchi PL, Chindamo D, Bisogno S, Ghittoni R, Natale MR, Caporali F, Giutini S, Marcolaongo R, Galeazzi M and Laghi-Pasini F (2007) Simvastatin inhibits cytokine production and nuclear factor-kB activation in interleukin 1beta-stimulated synoviocytes from rheumatoid arthritis patients. Clinical and Experimental Rheumatology 25 696-700
Le VT, Trilling M, Zimmermann A and Hengel H (2008) Mouse cytomegalovirus inhibits beta interferon (IFN-beta) gene expression and controls activation pathways of the IFN-beta enhanceosome. Journal of General Virology 89 1131-1141
Le Y, Iribarren P, Gong W, Cui Y, Zhang X, Wang JM (2004) TGF-beta1 disrupts endotoxin signaling in microglial cells through Smad3 and MAPK pathways. Journal of Immunology 173 962-968
Le Bail O, Schmidt-Ullrich and Israël A (1993) Promoter analysis of the gene encoding the IkBa/MAD3 inhibitor of NF-kB: positive regulation by members of the rel/NF-kB family. EMBO Journal 12 5043-5049
Le Beau MM, Ito C, Cogswell P, Espinosa III R, Fernald AA and Baldwin Jr AS (1992) Chromosomal localization of the genes encoding the p50/p105 subunits of NF-kB (NFKB2) and the IkB/MAD-3 (NFKBI) inhibitor of NF-kB to 4q24 and 14q13, respectively. Genomics 14 529-531
Le Bon A, Montoya M, Edwards MJ, Thompson C, Bruke SA, Ashton M, Lo D, Tough DF and Borrow P (2006) A role for the transcription factor RelB in IFN-a production and in IFN-a-stimulated cross-priming. European Journal of Immunology in press
Le Bras M, Rouy I and Brenner C (2006) The modulation of inter-organelle cross-talk to control apoptosis. Medicinal Chemistry 2 1-12
Le Clorennec C, Ouk TS, Youlyouz-Marfak I, Panteix S, Martin CC, Rastelli J, Adriaenssens E, Zimber-Strobl U, Coll J, Feullard J and Jayat-Vignoles C (2008) Molecular basis of Epstein-Barr virus latent membrane protein 1 (LMP1) cytotoxicity in EBV latency III B-cells: LMP1 induces type II ligand independent autoactivation of CD95/Fas with Caspase-8 mediated apoptosis. Journal of Virology in press
Le Clorennec C, Youlyouz-Marfak I, Adriaenssens E, Coll J, Bornkamm GW and Feuillard J (2006) EBV Latency III immortalization program sensitizes B-cells to induction of CD95 mediated apoptosis via LMP1: role of NF-kB, STAT1 and p53.Blood 107 2070-2078
Le Mandat Schultz A, Bonnard A, Barreau F, Aigrain Y, Pierre-Louis C, Berrebi D and Peuchmaur M (2007) Expression of TLR-2, TLR-4, NOD2 and NF-kB in a neonatal rat model of necrotizing enterocolitis. PLoS ONE 2 e1102
Le Negrate G, Faustin B, Welsh K, Loeffler M, Krajewska M, Hasegawa P, Mukherjee S, Orth K, Krajewski S, Godzik A, Guiney DG and Reed JC (2008) Salmonella secreted factor L deubiquitinase of Salmonella typhimurium inhibits NF-kB, suppresses IkBa ubiquitination and modulates innate immune responses. Journal of Immunology 180 5045-5056
Le Negrate G, Krieg A, Faustin B, Loeffler M, Godzik A, Krajewski S and Reed JC (2008) ChlaDub1 of Chlamydia trachomatis suppresses NF-kB activation and inhibits IkBa ubiquitination and degradation. Cellular Microbiology in press
Le Page C, Koumakpayi IH, Lessard L, Mes-Masson AM and Saad F (2005) EGFR and Her-2 regulate the constitutive activation of NF-kB in PC-3 prostate cancer cells. Prostate 65 306-315
Le Page C, Koumakpayi IH, Lessard L, Saad F and Mes-Masson AM (2005) Independent role of phosphoinositol-3-kinase (PI3K) and casein kinase II (CK-2) in EGFR and Her-2-mediated constitutive NF-kB activation in prostate cancer cells. Prostate in press
Le Page C, Popescu O, Genin P, Lian J, Paquin A, Galipeau J and Hiscott J (2001) Disruption of NF-kB signaling and chemokine gene activation by retroviral mediated expression of IKKg/NEMO mutants. Virology 286 422-433
Le Page C, Sanceau J, Drapier JC and Wietzerbin J (1998) Inhibitors of ADP-ribosylation impair inducible nitric oxide synthase gene transcription through inhibition of NF kappa B activation. Biochemical and Biophysical Research Communications 243 451-457
Le Page C and Wietzerbin J (2003) Modulation of the activation of extracellular signal-regulated kinase (ERK) and the production of inflammatory mediators by ADP-ribosylation inhibitors. Biol Chem 384 1509-1513
Le Tulzo Y, Shenkar R, Kaneko D, Moine P, Fantuzzi G, Dinarello CA and Abraham E (1997) Hemorrhage increases cytokine expression in lung mononuclear cells in mice: involvement of catecholamines in Nuclear Factor-kB regulation and cytokine expression. Journal of Clinical Investigation 99 1516-1524
Lean J, Kirstein B, Urry Z, Chambers T and Fuller K (2004) Thioredoxin-1 mediates osteoclast stimulation by reactive oxygen species. Biochemical and Biophysical Research Communications 321 845-850
Lean JM, Davies JT, Fuller K, Jagger CJ, Kirstein B, Partington GA, Urry ZL and Chambers TJ (2003) A crucial role for thiol antioxidants in estrogen-deficiency bone loss. Journal of Clinical Investigation 112 915-923
Leban J, Baierl M, Mies J, Trentinaglia V, Rath S, Kronthaler K, Wolf K, Gotschlich A and Seifer MH (2007) A novel class of potent NF-kB signaling inhibitors. Bioorganic & Medicinal Chemistry Letters in press
Leblanc PM, Yertssian G, Rutherford N, Doiron K, Nadiri A, Zhu L, Green DR, Gruenheid S and Saleh M (2008) Caspase-12 modulates NOD signaling and regulates antimicrobial peptide production and mucosal immunity. Cell Host Microbe 3 146-157
LeBlanc R, Hideshima T, Catley LP, Shringarpure R, Burger R, Mitsiades N, Mitsiades C, Cheema P, Chauhan D, Richardson PG, Anderson KC and Munshi NC (2004) Immunomodulatory drug co-stimulates T cells via the B7-CD28 pathway. Blood 103 1787-1790
Leblanc V, Dery MC, Shooner C and Asselin E (2003) Opposite regulation of XIAP and Smac/DIABLO in the rat endometrium in response to 17beta-estradiol at estrus. Reprod Biol Endocrinol 1 59
Lebovic DI, Chao VA, Martini JF and Taylor RN (2001) IL-1beta induction of RANTES (regulated upon activation, normal T cell expressed and secreted) chemokine gene expression in endometriotic stromal cells depends on a nuclear factor-kB site in the proximal promoter. Journal of Clinical Endocrinology and Metabolism 86 4759-4764
Lebowitz J, Edinger RS, An B, Perry CJ, Onate S, Kleyman TR and Johnson JP (2004) IKKbeta modulation of epithelium sodium channel activity. Journal of Biological Chemistry 279 41985-41990
Lebron F, Vassallo R, Puri V and Limper AH (2003) Pneumocystis carinii cell wall beta-glucans initiate macrophage inflammatory responses through NF-kB activation. Journal of Biological Chemistry 278 25001-25008
Lebruska LL and Maher LJ, 3rd (1999) Selection and characterization of an RNA decoy for transcription factor NF-kB. Biochemistry 38 3168-3174
Lecain E, Omri B, Behar-Cohen F, Tran Ba Huy P and Crisanti P (2007) The role of PKCzeta in amikacin-induced apoptosis in the cochlea: Prevention by aspirin.Apoptosis 12 333-342
Lecine P, Esmiol S, Metais JY, Nicoletti C, Nourry C, McDonald C, Nunez G, Hugot JP, Borg JP and Ollendorff V (2007) The NOD2-RICK complex signals from the plasma membrane. Journal of Biological Chemistry in press
LeClair KP, Blanar MA and Sharp PA (1992) The p50 subunit of NF-kB associates with the NF-IL6 transcription factor. Proceedings of the National Academy of Sciences USA 89 8145-8149
Leclercq IA, Farrell GC, Sempoux C, Pena AD and Horsmans Y (2004) Curcumin inhibits NF-kB activation and reduces the severity of experimental steatohepatitis in mice. Journal of Hepatology 41 926-934
Leclercq IA, Field J and Farrell GC (2003) Leptin-specific mechanisms for impaired liver regeneration in ob/ob mice after toxic injury. Gastroenterology 124 1451-1464
Lecureur V, Ferrec EL, N’diaye M, Vee ML, Gardyn C, Gilot D and Fardel O (2005) ERK-dependent induction of TNFalpha expression by the environmental contaminant benzo(a)pyrene in primary human macrophages. FEBS Letters 579 1904-1910
Ledeboer A, Gamanos M, Lai W, Martin D, Maier SF, Watkins LR and Quan N (2005) Involvement of spinal cord nuclear factor kB activation in rat models of proinflammatory cytokine-mediated pain facilitation. European Journal of Neuroscience 22 1977-1986
Ledebur HC and Parks TP (1995) Transcriptional regulation of the intercellular adhesion molecule-1 gene by inflammatory cytokines in human endothelial cells. Essential roles of a variant NF-kB site and p65 homodimers. Journal of Biological Chemistry 270 933-943
Lederer JA, Liou JS, Kim S, Rice N and Lichtman AH (1996) Regulation of NF-kB activation in T helper 1 and T helper 2 cells. Journal of Immunology 156 56-63
Ledoux S, Yang R, Friedlander G and Laouari D (2003) Glucose depletion enhances p-glycoprotein expression in hepatoma cells: role of endoplasmic reticulum stress response. Cancer Research 63 7284-7290
Lee AK, Sung SH, Kim YC and Kim SG (2003) Inhibition of lipopolysaccharide-inducible nitric oxide synthase, TNF-alpha and COX-2 expression by sauchinone effects on I-kBa phosphorylation, C/EBP and AP-1 activation. British Journal of Pharmacology 139 11-20
Lee B and Moon SK (2005) Resveratrol inhibits TNF-a-induced proliferation and matrix metalloproteinase expression in human vascular smooth muscle cells.Journal of Nutrition 135 2767-2773
Lee B, Park S, Kang K, Park R and Kim I (2002) NF-kB activates fibronectin gene expression in rat hepatocytes. Biochemical and Biophysical Research Communications 297 1218
Lee BC, Kim SH, Choi SH and Kim TS (2005) Induction of interleukin-8 production via nuclear factor-kB activation in human intestinal epithelial cells infected with Vibrio vulnificus. Immunology 115 506-515
Lee BH, Kim MS, Rhew JH, Park RW, de Crombrugghe B and Kim IS (2000) Transcriptional regulation of fibronectin gene by phorbol myristate acetate in hepatoma cells: a negative role for NF-kB. Journal of Cellular Biochemistry 76 437-451
Lee BH and Ruoslahti E (2005) alpha(5)beta(1) integrin stimulates Bcl-2 expression and cell survival through Akt, focal adhesion kinase, and Ca(2+)/calmodulin-dependent protein kinase IV. Journal of Cellular Biochemistry 95 1214-1223
Lee BL, Lee HS, Jung J, Cho SJ, Chung HY, Kim WH, Jin YW, Kim CS and Nam SY (2005) Nuclear factor kB activation correlates with better prognosis and Akt activation in human gastric cancer. Clinical Cancer Research 11 2518-2525
Lee BN, Dantzer R, Langley KE, Bennett GJ, Dougherty PM, Dunn AJ, Meyers CA, Miller AH, Payne R, Reuben JM, Wang XS and Cleeland CS (2004) A cytokine-based neuroimmunologic mechanism of cancer-related symptoms. Neuroimmodulation 11 279-292
Lee BS, Heo J, Kim YM, Shim SM, Pae HO, Kim YM and Chung HT (2006) Carbon monoxide mediates heme oxygenase 1 induction via Nrf2 activation in hepatoma cells. Biochemical and Biophysical Research Communications 343 965-972
Lee BS, Paulose-Murphy M, Chung YH, Connlole M, Zeichner S and Jung JU (2002) Suppression of tetradecanoyl phorbol acetate-induced lytic reactivation of Kaposi’s Sarcoma-associated herpesvirus by K1 signal transduction. Journal of Virology 76 12185-12199
Lee C, Schwartz MP, Prakash S, Iwakura M and Matouschek A (2001) ATP-dependent proteases degrade their substrates by processively unraveling them from the degradation signal. Molecular Cell 7 627-637
Lee CC, Cheng YW and Kang JJ (2005) Motorcycle exhaust particles induce IL-8 production through NF-kB activation in human airway epithelial cells. Journal of Toxicology and Environmental Health A 68 1537-1555
Lee CH, Jeon YT, Kim SH and Song YS (2007) NF-kB as a potential molecular target for cancer therapy. Biofactors 29 19-35
Lee CH, Shieh DC, Tzeng CY, Chen CP, Wang SP, Chiu YC, Huang CY, Hsu CJ, Fong YC and Tang CH (2008) Bradykinin-induced IL-6 expression through bradykinin B2 receptor, phospholipase C, protein kinase Cdelta and NF-kB pathway in human synovial fibroblasts. Molecular Immunology in press
Lee CJ, Lee SS, Chen SC, Ho FM and Lin WW (2005) Oregonin inhibits lipopolysaccharide-induced iNOS gene transcription and upregulates HO-1 expression in macrophages and microglia. British Journal of Pharmacology 146 378-388
Lee CK, Lee EY, Chung SM, Mun SH, Yoo B and Moon HB (2004) Effects of disease-modifying antirheumatic drugs and antiinflammatory cytokines on human osteoclastogenesis through interaction with receptor activator of nuclear factor kB, osteoprotegerin, and receptor activator of nuclear factor kB ligand. Arthritis and Rheumatism 50 3831-3843
Lee CK, Lee EY, Kim YG, Mun SH, Moon HB and Yoo B (0208) Alpha-lipoic acid inhibits TNF-alpha induced NF-kB activation through blocking of MEKK1-MKK4-IKK signaling cascades. Interntational Immunopharmacology 8 362-370
Lee CT, Seol JY, Lee SY, Park KH, Han SJ, Yoo CG, Han SK, Shim YS and Kim YW (2003) The effect of adenovirus-IkBa transduction on the chemosensitivity of lung cancer cell line with resistance to cis-diamminedichloroplatinum(II)(cisplatin) and doxorubicin(adriamycin). Lung Cancer 41 199-206
Lee CW, Lin CC, Lin WN, Liang KC, Luo SF, Wu CB, Wang SW and Yang CM (2006) TNF-a induces MMP-9 expression via activation of Src/EGFR, PDGFR/PI3K/Akt cascade and promotion of NF-kB/p300 binding in human tracheal smooth muscle cells.American Journal of Physiology: Lung Cell and Molecular Physiology in press
Lee CW, Lin WN, Lin CC, Luo SF, Wang JS, Pouyssegur J and Yang CM (2006) Transcriptional regulation of VCAM-1 expression by tumor necrosis factor-alpha in human tracheal smooth muscle cells: Involvement of MAPKs, NF-kB, p300, and histone acetylation. Journal of Cellular Physiology 207 174-186
Lee CW, Lin CC< Luo SF, Lee HC, Lee IT, Aird WC, Hwang Tl and Yang CM (2008) TNF-a enhances neutrophil adhesiveness: Induction of VCAM-1 via activation of Akt and CaM kinase II and modification of HAT and HDAC4 in human tracheal smooth muscle cells. Molecular Pharmacology in press
Lee DC, Cheung CY, Law AH, Mok CK, Peiris M and Lau AS (2005) p38 mitogen-activated protein kinase-dependent hyperinduction of tumor necrosis factor alpha expression in response to avian influenza virus H5N1. Journal of Virology 79 10147-10154
Lee DH, Cho KS, Park SG, Kim EK and Joo CK (2005) Cellular death mediated by nuclear factor kB (NF-kB) translocation in cultured human lens epithelial cells after ultraviolet-B irradiation. J Cataract Refract Surg 31 614-619
Lee DH, Kim JK and Joo CK (2005) Translocation of nuclear factor-kB on corneal epithelial cells induced by ultraviolet B irradiation. Ophthalmic Research 37 83-88
Lee DH, Kim SH, Eun JS and Shin TY (2006) Mosla dianthera inhibits mast cell-mediated allergic reactions through the inhibition of histamine release and inflammatory cytokine production. Toxicology and Applied Pharmacology in press
Lee DH, Macintyre JP, Taylor GR, Wang E, Plante RK, Tam SS, Pope BL and Lau CY (1999) Tepoxalin enhances the activity of an antioxidant, pyrrolidine dithiocarbamate, in attenuating tumor necrosis factor alpha-induced apoptosis in WEHI 164 cells. Journal of Pharmacology and Experimental Therapeutics 289 1465-1471
Lee DH, Tam SS, Wang E, Taylor GR, Plante RK and Lau CY (1996) The NF-kB inhibitor, tepoxalin, suppresses surface expression of the cell adhesion molecules CD62E, CD11b/CD18 and CD106. Immunology Letters 53 109-113
Lee DJ, Cox D, Li J and Greenberg S (2000) Rac1 and Cdc42 are required for phagocytosis, but not NF-kB-dependent gene expression, in macrophages challenged with Pseudomonas aeruginosa. Journal of Biological Chemistry 275 141-146
Lee DK, Kang JE, Park HJ, Kim MH, Yim TH, Kim JM, Heo MK, Kim KY, Kwon HJ and Hur MW (2005) FBI-1 enhances transcription of NF-kB responsive E-selectin gene by nuclear localization of p65 subunit of NF-kB. Journal of Biological Chemistry 280 27783-27791
Lee EC and Tenniswood M (2004) Programmed cell death and survival pathways in prostate cancer cells. Annals of Andrology 50 27-32
Lee EG, Boone DL, Chai S, Libby SL, Chein M, Lodolce JP and Ma A (2000) Failure to regulate TNF-induced NF-kB and cell death responses in A20-deficient mice. Science 289 2351-2354
Lee EJ, Seo SR, Um JW, Park J, Oh Y and Chung KC (2008) NF-kB-inducing kinase phosphorylates and blocks the degradation of Down Syndrome candidate region 1. Journal of Biology Chemistry in press
Lee ES, Ju HK, Moon TC, Lee E, Jahng Y, Lee SH, Son JK, Baek SH and Chang HW (2004) Inhibition of nitric oxide and tumor necrosis factor-alpha (TNF-alpha) production by propenone compound through blockade of nuclear factor (NF)-kB activation in cultured murine macrophages. Biol Pharm Bull 27 617-620
Lee ES, Kalantari P, Tsutsui Section S, Klatt A, Holden J, Correll PH, Power Section C and Henderson AJ (2004) RON receptor tyrosine kinase, a negative regulator of inflammation, inhibits HIV-1 transcription in monocytes/macrophages and is decreased in brain tissue from patients with AIDS. Journal of Immunology 173 6864-6872
Lee EY, Lee CK, Lee KU, Park JY, Cho KJ, Cho YS, Lee HR, Moon SH, Moon HB and Yoo B (2006) Alpha-lipoic acid suppresses the development of collagen-induced arthritis and protects against bone destruction in mice. RheumatologyInternational in press
Lee FS, Hagler J, Chen ZJ and Maniatis T (1997) Activation of the IkBa kinase complex by MEKK1, a kinase of the JNK pathway. Cell 88 213-222
Lee FS, Peters RT, Dang LC and Maniatis T (1998) MEKK1 activates both IkB kinase a and IkB kinase b. Proceedings of the National Academy of Sciences USA 95 9319-9324
Lee FT, Cao Z, Long DM, Panagiotopoulos S, Jerums G, Cooper ME and Forbes JM (2004) Interactions between angiotensin II and NF-kB-dependent pathways in modulating macrophage infiltration in experimental diabetic nephropathy. Journal of the American Society of Nephrology 15 2139-2151
Lee FY, Kim DW, Karmin JA, Hong D, Chang SS, Fujisawa M, Takayanagi H, Bigliani LU, Blaine TA and Lee HJ (2005) mu-calpain regulates RANKL-supported osteoclastogenesis via NF-kB activation in raw 264.7 cells. Journal of Biological Chemistry 280 29929-29936
Lee FY, Li Y, Zhu H, Yang S, Lin HZ, Trush M and Diehl AM (1999) Tumor necrosis factor increases mitochondrial oxidant production and induces expression of uncoupling protein-2 in the regenerating mice [correction of rat] liver. Hepatology 29 677-687
Lee G, Na HJ, Namkoong S, Kwon HJ, Han S, Ha KS, Kwon YG, Lee H and Kim YM (2006) 4-O-methylgallic acid down-regulates endothelial adhesion molecule expression by inhibiting NF-kB-DNA-binding activity. European Journal ofPharmacology in press
Lee GC, Yi HA and Lee CH (2006) Stimulation of intereron-beta gene expression by human cytomegalovirus via nuclear factor kB and phosphatiylinosital 3-kinasse pathway. Virus Research 117 209-214
Lee GS, Choi KC, Han HJ and Jeung EB (2007) The classical and a non-classical pathways associated with NF-kB are involved in estrogen-medicated regulation of Calbindin-D9k gene in rat pituitary cells. Molecular and Cellular Endocrinology in press
Lee GT, Ha H, Lee HC and Cho YD (2003) Agmatine reduces hydrogen peroxide in mesangial cells under high glucose conditions. Journal of Biochemistry and Molecular Biology 36 251-257
Lee H, Arsura M, Wu M, Duyao M, Buckler AJ and Sonenshein GE (1995) Role of Rel-related factors in control of c-myc gene transcription in receptor-mediated apoptosis of the murine B cell WEHI 231 line. Journal of Experimental Medicine 181 1169-1177
Lee H, Choi JK, Li M, Kaye K, Kieff E and Jung JU (1999) Role of cellular tumor necrosis factor receptor-associated factors in NF-kB activation and lymphocyte transformation by herpesvirus Saimiri STP. Journal of Virology 73 3913-3919
Lee H, Jeong J, Son E, Mosa A, Cho GJ, Choi WS, Ha JH, Kim IK, Lee MG, Kim CY and Suk K (2004) Ethanol selectively modulates inflammatory activation signaling of brain microglia. Journal of Neuroimmunology 156 88-95
Lee H, Kim YO, Kim H, Kim SY, Noh HS, Kang SS, Cho GJ, Choi WS and Suk K (2003) Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia. FASEB Journal 17 1943-1944
Lee H, Kong SW and Park PJ (2008) Integrative analysis reveals the direct and indirect interactions between DNA copy number aberrations and gene expression changes. Bioinformatics in press
Lee H, Lin CI, Liao JJ, Lee YW, Yang HY, Lee CY, Hsu HY and Wu HL (2004) Lysophospholipids increase ICAM-1 expression in human umbilical cord vein endothelial cells through a Gi- and NFkB-dependent mechanism. American Journal of Physiology: Cellular Physiology 287 C1657-C1666
Lee H, Park C,Cho IH,Kim HY, Jo EK, Lee S, Kho HS, Choi SY, Bae oh S, Park K, Kim JS and Lee SJ (2007) Double-stranded RNA induces iNOS gene expression in Schwann cells, sensory neuronal death, and peripheral nerve demyelination. Gliain press
Lee H, Pespeni M, Roux J, Dennery PA, Matthay MA and Pittet JF (2004) HO-1 induction restores c-AMP-dependent lung epithelial fluid transport following severe hemorrhage in rats. FASEB Journal 19 287-289
Lee H and Suk K (2004) Selective modulation of microglial signal transduction by PACAP. Neuroreport 15 1469-1474
Lee H, Wu M, La Rosa FA, Duyao MP, Buckler AJ and Sonenshein GE (1995) Role of Rel-family of transcription factors in the regulation of c-myc gene transcription and apoptosis of WEHI 231 murine B-cells. Current Topics in Microbiology and Immunology 194 247-255
Lee HA and Hughes DA (2001) Alpha-lipoic acid modulates NF-kB activity in human monocytic cells by direct interaction with DNA. Experimental Gerontology 37 401-410
Lee HB, Yu MR, Yang Y, Jiang Z and Ha H (2003) Reactive oxygen species-regulated signaling pathways in diabetic nephropathy. American Journal of the American Society of Nephrology 14 S241-S245
Lee HC and Goodman JL (2006) Anaplasma phagocytophilum causes global induction of antiapoptosis in human neutrophils. Genomics 88 496-503
Lee HC and Ziegler SF (2007) Inducible expression of the proallergic cytokine thymic stromal lymphopoietin in airway epithelial cells is controlled by NFkB.Proceedings of the National Academy of Sciences USA in press
Lee HG, Kim H, Oh WK, Yu KA, Choe YK, Ahn JS, Kim DS, Kim SH, Dinarello CA, Kim K and Yoon DY (2004) Tetramethoxy hydroxyflavone p7F downregulates inflammatory mediators via the inhibition of nuclear factor kB. Annals of the New York Academy of Sciences 1030 555-568
Lee HJ, Lee DY, Joo WA, Sul D, Lee E and Kim CW (2004) Differential expression of proteins in rat plasma exposed to benzene. Proteomics 4 3498-3504
Lee HJ, Oh TH, Yoon WJ, Kang GJ, Yang EJ, Park SS, Lee NH, Kang HK and Yoo ES (2008) Eutigoside C inhibits the production of inflammatory mediators (NO, PGE(2), IL-6) by down-regulating NF-kB and MAP kinase activity in LPS-stimulated RAW 264.7 cells. Journal of Pharmacy and Pharmacology 60 917-924
Lee HH, Dadgostar H, Cheng Q, Shu J and Cheng G (1999) NF-kB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes. Proceedings of the National Academy of Sciences USA 96 9136-9141
Lee HH, Dempsey PW, Parks TP, Zhu X, Baltimore D and Cheng G (1999) Specificities of CD40 signaling: involvement of TRAF2 in CD40-induced NF-kappaB activation and intercellular adhesion molecule-1 up-regulation. Proceedings of the National Academy of Sciences USA 96 1421-1426
Lee HH, Shiow SJ, Chung HC, Huang CY, Lin CL, Hsu JD, Shyu LY and Wang CJ (2000) Development of brain injury in mice by Angiostrongylus cantonensis infection is associated with the induction of transcription factor NF-kB, nuclear protooncogenes, and protein tyrosine phosphorylation. Experimental Parasitology 95 202-208
Lee HJ, Cho JW, Kim SC, Kang KH, Lee SK, Pi SH, Lee SK and Kim EC (2006) Roles of p38 and ERK MAP kinases in IL-8 expression in TNF-a- and dexamethasone-stimulated human periodontal ligament cells. Cytokine 35 67-76
Lee HJ, Jeong HS, Kim DJ, Noh YH, Yuk DY and Hong JT (2008) Inhibitory effect of citral on NO production by suppression of iNOS expression and NF-kB activation in RAW264.7 cells. Archives of Pharmacal Research 31 342-349
Lee HJ, Lee J, Lee SK, Lee SK and Kim EC (2007) Differential regulation of iron chelator-induced IL-8 synthesis via MAP kinase and NF-kB in immortalized and malignant oral keratinocytes. BMC Cancer 7 176
Lee HJ, Lee J, Min SK, Guo HY, Lee SK, Kim HR, Pae HO, Chung HT, Hong SH, Lee SK and Kim EC (2008) Differential induction of heme oxygenase-1 against nicotine-induced cytotoxicity via the PI3K, MAPK, and NF-kB pathways in immortalized and malignant human oral keratinocytes. Journal of Oral Pathology and Medicine in press
Lee HJ, Oh YK, Rhee M, Lim JY, Hwang JY, Park YS, Kwon Y, Choi KH, Jo I, Park SJ, Gao B and Kim WH (2007) The role of STAT1/IRF-1 on synergistic ROS production and loss of mitochondrial transmembrane potential during hepatic cell death induced by LPS/d-GalN. Jounral of Molecular Biology in press
Lee HK, Lee J and Tobias PS (2002) Two lipoproteins extracted from Escherichia coli K-12 LCD25 lipopolysaccharide are the major components responsible for Toll-like receptor 2-mediated signaling. Journal of Immunology 168 4012-4017
Lee HO, Lee JH, Kim TY and Lee H (2007) Regulation of DeltaNp63alpha by tumor necrosis factor-alpha in epithelial homeostasis. FEBS Journal in press
Lee HR, Cheong HJ, Kim SJ, Lee NS, Park HS and Won JH (2008) Sulindac enhances arsenic trioxide-mediated apoptosis by inhibition of NF-kB in HCT116 colon cancer cells. Oncology Reports 20 41-47
Lee HS, Chang JS, Baek JA, Chung MY, Lee HC, Rhim BY, Sok DE, Rho MC, Kim YK and Kim K (2005) TNF-alpha activates death pathway in human aorta smooth muscle cell in the presence of 7-ketocholesterol. Biochemical and Biophysical Research Communications 333 1093-1099
Lee HS, Choi CY, Cho C and Song Y (2003) Attenuating effect of Chlorella supplementation on oxidative stress and NFkB activation in peritoneal macrophages and liver of C57BL/6 mice fed on an atherogenic diet. Biosci Biotechnol Biochem 67 2083-2090
Lee HS, Kim HJ, Moon CS, Chong YH and Kang JL (2004) Inhibition of c-Jun NH2-terminal kinase or extracellular signal-regulated kinase improves lung injury. Respiration Research 5 23
Lee HS, Lee CH, Tsai HC and Salter DM (2008) Inhibition of cyclooxygenase 2 expression by diallyl sulfide on joint inflammation induced by urate crystal and IL-1b. Osteoarthitis and Cartilage in press
Lee HS, Moon C, Lee HW, Park EM, Cho MS and Kang JL (2007) Src tyrosine kinases mediate activations of NF-kB and integrin signal during lipopolysaccharide-induced acute lung injury. Journal of Immunology 179 7001-7011
Lee HT, Chen SW, Doetschman TC, Deng C, D’Agati VD and Kim M (2008) Sevoflurane protects against renal ischemia and reperfusion injury in mice via the transforming growth factor-beta1 pathway. American Journal of Physiology: Renal Physiology in press
Lee HT, Ota-Setlik A, Fu Y, Nasr SH and Emala CW (2004) Differential protective effects of volatile anesthetics against renal ischemia-reperfusion injury in vivo. Anesthesiology 101 1313-1324
Lee HT, Kim M, Jan M and Emala CW (2006) Anti-inflammatory and anti-necrotic effects of the volatile anesthetic sevoflurane in kidney proximal tubule cells.American Journal of Physiology: Renal Physiology 291 F67-F78
Lee HW, Ahn DH, Crawley SC, Li JD, Gum JR Jr, Basbaum CB, Fan NQ, Szymkowski DE, Han SY, Lee BH, Sleisenger MH and Kim YS (2002) Phorbol 12-myristate 13-acetate up-regulates the transcription of MUC2 intestinal mucin via Ras, ERK, and NF-kB. Journal of Biolgoical Chemistry 277 32624-32631
Lee HW, Kim BS, Kim HJ, Lee CW, Yoo HJ, Kim JB and Yoon S (2005) Upregulation of receptor activator of nuclear factor-kappaB ligand expression in the thymic subcapsular, paraseptal, perivascular, and medullary epithelial cells during thymus regeneration. Histochemistry and Cell Biology 123 491-5400
Lee HW, Park SJ, Choi BK, Kim HH, Nam KO and Kwon BS (2002) 4-1BB promotes the survival of CD8(+) T lymphocytes by increasing expression of Bcl-x(L) and Bfl-1. Journal of Immunology 169 4882-4888
Lee HW, Park HK, Na YJ, Kim CD, Lee JH, Kim BS, Kim JB, Lee CW, Moon JO and Yoon S (2008) RANKL stimulates proliferation, adhesion and IL-7 expression of thymic epithelial cells. Experimental Molecular Medicine 40 59-70
Lee HY, Jeon HS, Song EK, Han MK, Park SL, Lee SI, Yun HJ, Kim JR, Kim JS, Lee YC, Kim SI, Kim HR, Choi JY, Kang I, Kim HY and Yoo WH (2006) CD40 ligation of rheumatoid synovial fibroblasts regulates RANKL-medicated osteoclastogenesis: Evidence of NF-kB-dependent, CD40-mediated bone destruction in rheumatoid arthritis. Arthritis and Rheumatism 54 1747-1758
Lee HY, Kim MK, Park KS, Bae YH, Yun J, Park JI, Kwak JY and Bae YS (2005) Serum amyloid A stimulates matrix-metalloproteinase-9 upregulation via formyl peptide receptor like-1-mediated signaling in human monocytic cells. Biochemical and Biophysical Research Communications 330 989-998
Lee HY, Park KS, Kim MK, Lee T, Ryun SH, Woo KJ, Kwon TK and Bae YS (2005) A small compound that inhibits tumor necrosis factor-alpha-induced matrix metalloproteinase-9 upregulation. Biochemical and Biophsyical Research Communications in press
Lee HY, Youn SW, Kim JY, Park KW, Hwang CI, Park WY, Oh BH, Park YB, Walsh K, Seo JS and Kim HS (2007) FOXO3a turns the tumor necrosis factor receptor signaling towards apoptosis through reciprocal regulation of c-Jun N-terminal kinase and NF-kB. Arteriosclerosis, Thrombosis, and Vascular Biology in press
Lee I, Kim MK, Choi EY, Mehl A, Jung KC, Gil MC, Rowe M and Park SH (2001) CD99 expression is positively regulated by Sp1 and is negatively regulated by Epstein-Barr virus latent membrane protein 1 through nuclear factor-kB. Blood 97 3596-3604
Lee IO, Lee KH, Pyo JH, Kim JH, Choi YJ and Lee YC (2007) Anti-inflammatory effect of capsaicin in Helicobacter pylori-infected gastric epithelial cells.Helicobacter 12 510-517
Lee IS, Kim SH, Song HG and Park SH (2003) The molecular basis for the generation of Hodgkin and Reed-Sternberg cells in Hodgkin’s lymphoma. International Journal of Hematology 77 330-335
Lee IS, Shin YK, Chung DH and Park SH (2001) LMP1-induced downregulation of CD99 molecules in Hodgkin and Reed-Sternberg cells. Leukemia and Lymphoma 42 587-594
Lee J, Chuang TH, Redecke V, She L, Pitha PM, Carson DA, Raz E and Cottam HB (2003) Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of Toll-like receptor 7. Proceedings of the National Academy of Sciences USA 100 6646-6651
Lee J, Ho WH, Maruoka M, Corpuz RT, Baldwin DT, Foster JS, Goddard AD, Yansura DG, Vandlen RL, Wood WI and Gurney AL (2001) IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1. Journal of Biological Chemistry 276 1660-1664
Lee J, Im YH, Jung HH, Kim JH, Park JO, Kim K, Kim WS, Ahn JS, Jung CW, Park YS, Kang WK and Park K (2005) Curcumin inhibits interferon-alpha induced NF-kB and COX-2 in human A549 non-small cell lung cancer cells. Biochemical and Biophysical Research Communications 334 313-318
Lee J, Jung E, Kim Y, Lee J, Park J, Hong S, Hyun CG, Park D and Kim YS (2006) Rosmarinic acid as a downstream inhibitor of IKK-b in TNF-a-induced upregulation of CCL11 and CCR3. British Journal of Pharmacology 148 366-375
Lee J, Jung E, Lim J, Lee J, Hur S, Kim SS, Lim S, Hyun CG, Kim YS and Park D (2006) Involvement of nuclear factor-kB in the inhibition of pro-inflammatory mediators by pinosylvin. Planta Medica in press
Lee J, Jung E, Park J, Jung K, Lee S, Hong S, Park J, Park E, Kim J, Park S and Park D (2005) Anti-inflammatory effects of magnolol and honokiol are mediated through inhibition of the downstream pathway of MEKK-1 in NF-kB activation signaling. Planta Med 71 338-343
Lee J, Jung E, Park J, Jung K, Park E, Kim J, Hong S, Park J, Park S, Lee S and Park D (2005) Glycyrrhizin induces melanogenesis by elevating a cAMP level in b16 melanoma cells. Journal of Investigative Dermatology 124 405-411
Lee J, Jung E, Park B, Jung K, Park J, Kim K, Kim KH and Park D (2005) Evaluation of the anti-inflammatory and atopic dermatitis-mitigating effects of BSASM, a multicompound preparation. Journal of Ethnopharmacology 96 211-219
Lee J, Jung E, Park J and Park D (2005) Transdermal delivery of interferon gamma (IFN gamma) mediated by penetratin, a cell-permeable peptide. Biotechnology and Applied Biochemistry 42 169-173
Lee J, Jung KD, Park CG, Han JW and Lee HY (2006) Autotaxin stimulates urokinase-type plasminogen activator expression through phosphoinositide 3-kinase-Akt-necrosis factor kB signaling cascade in human melanoma cells.Melanoma Research 16 445-452
Lee J, Kim MS, Kim EY, Park HJ, Chang CY, Park KS, Jung DY, Kwon CH, Joh JW and Kim SJ (2008) Mycophenolate mofetil promotes down-regulation of expanded B cells and production of TNF-a in an experimental murine model of colitis. Cytokine in press
Lee J, Kim YS, Choi DH, Bang MS, Han TR, Joe TH and Kim SY (2004) Transglutaminase 2 induces NF-kB activation via a novel pathway in BV-2 microglia. Journal of Biological Chemistry 279 53725-53735
Lee J, Mo JH, Katakura K, Alkalay I, Rucker AN, Liu YT, Lee HK, Shen C, Cojocaru G, Shenouda S, Kagnoff M, Eckmann L, Ben-Neriah Y and Raz E (2006) Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells. Nature Cell Biology 8 1327-1336
Lee J, Mo JH, Shen C, Rucker AN and Raz E (2007) Toll-like receptor signaling in intestinal epithelial cells contributes to colonic homoeostasis. Current Opinion in Gastroenterology 23 27-31
Lee J, Seo J, Kim H, Chung JB and Kim KH (2003) Signal transduction of cerulein-induced cytokine expression and apoptosis in pancreatic acinar cells. Annals of the New York Academy of Sciences 1010 104-108
Lee J, Shin S, Teng CH, Hong SJ and Kim KS (2005) FimH adhesin of Escherichia coli K1 type 1 fimbriae activates BV-2 microglia. Biochemical and Biophysical Research Communications 334 917-923
Lee J and Sugden B (2007) A membrane leucine heptad contributes to LMP1’s trafficking, signaling and transformation. Journal of Virology in press
Lee JA, Hwang JA, Sung HN, Jeon CH, Gill BC, Youn HJ and Park JH (2007) 2,3,7,8-tetrachlorodibenzo-p-dioxin modulates functional differentiation by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicological Letters in press
Lee JC, Kim J, Park JK, Chung GH and Jang YS (2003) The antioxidant, rather than prooxidant, activities of quercetin on normal cells: quercetin protects mouse thymocytes from glucose oxidase-mediated apoptosis. Experimental Cell Research 291 386-397
Lee JC, Kundu JK, Hwang DM, Na HK and Surh YJ (2007) Humulone inhibits phorbol ester-induced COX-2 expression in mouse skin by blocking activation of NF-kB and AP-1: IkB kinase and c-Jun-N-terminal kinase as respective potential upstream targets. Carcinogenesis 1491-1498
Lee JC, Lee KY, Son YO, Choi KC, Kim J, Truong TT and Jang YS (2005) Plant-originated glycoprotein, G-120, inhibits the growth of MCF-7 cells and induces their apoptosis. Food Chem Toxicol 43 961-968
Lee JC, Won SJ, Chao CL, Wu FL, Liu HS, Ling P, LIn CN and Su CL (2008) Morusin induces apoptosis and suppresses NF-kB activity in human colorectal cancer HT-29 cells. Biochemical and Biophysical Research Communications in press
Lee JE, Shin HH, Lee EA, Van Phan T and Choi HS (2007) Stimulation of osteoclastogenesis by enhanced levels of MIP-1alpha in BALB/c mice in vitro.Experimental Hematology 35 1100-1108
Lee JC, Yu MK, Lee R, Lee YH, Jeon JG, Jhee EC, Yoo ID and Yi HK (2008) Terrein reduces pulpal inflammation in human dental pulp cells. Journal of Endodology 34 433-437
Lee JH, Choi YH, Kang HS and Choi BT (2004) An aqueous extract of Platycodi radix inhibits LPS-induced NF-kB nuclear translocation in human cultured airway epithelial cells. International Journal of Molecular Medicine 13 843-847
Lee JH, Choi JK, Noh MS, Hwang BY, Hong YS and Lee JJ (2004) Anti-inflammatory effect of kamebakaurin in in vivo animal models. Planta Medica 70 526-530
Lee JH, Jung HS, Giang PM, Lee S, Jin X, Son PT, Lee D, Hong YS, Lee K and Lee JJ (2006) Blockade of NF-kB signaling pathway and anti-inflammatory activity of cardamomin, a chalcone analogue from Alpinia conchigera. Journal of Pharmacology and Experimental Therapeutics 316 271-278
Lee JH, Kim M, Im YS, Choi W, Byeon SH and Lee HK (2008) NFAT5 induction and its role in hyperosmolar stressed human limbal epithelial cells. Investigative Ophthalmology and Visual Sciences 49 1827-1835
Lee JH, Ko WS, Kim YH, Kang HS, Kim HD and Choi BT (2001) Anti-inflammatory effect of the aqueous extract from Lonicera japonica flower is related to inhibition of NF-kB activation through reducing I-kBa degradation in rat liver. International Journal of Molecular Medicine 7 79-83
Lee JH, Koo TH, Yoon H, Jung HS, Jin HZ, Lee K, HOng YS and Lee JJ (2006) Inhibition of NF-kB activation through targeting IkB kinase by celastrol, a quinone methide triterpenoid. Biochemical Pharmacology in press
Lee JH, Hwang BY, Kim KS, Nam JB, Hong YS and Lee JJ (2003) Suppression of RelA/p65 transactivation activity by a lignoid manassantin isolated from Saururus chinensis. Biochemical Pharmacology 66 1925-1933
Lee JH, Lee J, Seo GH, Kim CH and Ahn YS (2007) Heparin inhibits NF-kB activation and increases cell death in cerebral endothelial cells after oxygen-glucose deprivation. Journal of Molecular Neuroscience 32 145-154
Lee JH, Oh GT, Park SY, Choi JH, Park JG, Kim CD, Lee WS, Rhim BY, Shin YW and Hong KW (2005) Cilostazol reduces atherosclerosis by inhibition of superoxide and TNF-alpha formation in low-density lipoprotein receptor-null mice fed high cholesterol. J Pharmacol Exp Ther in press
Lee JH, Park EJ, Kim OS, Kim HY, Joe EH and Jou I (2005) Double-stranded RNA-activated protein kinase is required for the LPS-induced activation of STAT1 inflammatory signaling in rat brain glial cells. Glia 50 66-79
Lee J-H, Koo TH, Hwang BY and Lee JJ (2002) Kaurane diterpene, kamebakaurin, inhibits NF-kB by directly targeting DNA-binding activity of p50 and blocks the expression of antiapoptotic target genes. Journal of Biological Chemistry 277 18411-18420
Lee J-H, Li Y, Doerre S, Sista P, Ballard DW, Greene WC and Franza Jr BR (1991) A member of the set of NF-kB binding proteins, HIVEN86A, is a product of the human c-rel proto-oncogene. Oncogene 6 665-667
Lee J-I and Burckhart GJ (1999) Nuclear factor kB: important transcription factor and therapeutic target. Journal of Clinical Pharmacology 38 981-993
Lee JI, Ganster RW, Geller DA, Burckart GJ, Thomson AW and Lu L (1999) Cyclosporin A inhibits the expression of costimulatory molecules on in vitro-generated dendritic cells: association with reduced nuclear translocation of nuclear factor kB. Transplantation 68 1255-1263
Lee JJ, Huang WT, Shao DZ, Liao JF and Lin MT (2004) Blocking NF-kappaB activation may be an effective strategy in the Fever therapy. Japanese Journal of Physiology 53 367-375
Lee JJ, Liao HF, Yang YC, Liu CL, Chen YY, Lin CP and Chen YJ (2006) Platonin modulates differentiation and maturation of human monocyte-derived dendritic cells. International Immunopharmacology 6 287-293
Lee JK, Kim SH, Lewis EC, Azam T, Reznikov LL, Dinarello CA (2004) Differences in signaling pathways by IL-1{beta} and IL-18. Proceedings of the National Academy of Sciences USA 101 8815-8820
Lee JL, Chang CJ, Chueh LL and Lin CT (2006) Secreted Frizzled related protein 2 (sFRP2) decreases susceptibility to UV-induced apoptosis in primary culture of canine mammary gland tumors by NF-kB activation or JNK suppression. Breast Cancer Research and Treatment 100 49-58
Lee J, Ivanova EV, Seong IS, Cashorali T, Kohane I, Guella JF and Macdonald ME (2007) Unbiased gene expression analysis implicates the huntingtin polyglutamine tract in extra-mitochondrial energy metabolism. PLoS Genetics 3 e135
Lee JR (2003) Reactive oxygen species play roles on B cell surface receptor CD40-mediated proximal and distal signaling events: effects of an antioxidant, N-acetyl-L-cysteine treatment. Mol Cell Biochem 252 1-7
Lee JR, Ha YJ and Kim HJ (2003) Cutting edge: induced expression of a RhoA-specific guanine nucleotide exchange factor, p190RhoGEF, following CD40 stimulation and WEHI 231 B cell activation. Journal of Immunology 170 19-23
Lee JR, Seok CJ, Kim JS, Chang JM and Seo JW (2001) Expression of NF-kB and cytokines in chronic rejection of transplanted murine heart. Journal of Korean Medical Science 16 397-406
Lee JS, Jung ID, Jeong YI, Lee CM, Shin YK, Lee SY, Suh DS, Yoon MS, Lee KS, Choi YH, CHung HY and Park YM (2007) d-pinitol inhibits Th1 polarization via the suppression of dendritic cells. International Immunopharmacology 7 791-804
Lee JS, Kahlon SS, Culbreth R and Cooper AD, Jr. (1999) Modulation of monocyte chemokine production and nuclear factor kappa B activity by oxidants. Journal of Interferon and Cytokine Research 19 761-767
Lee JS, Kim HS, Hahm KB, Sohn MW, Yoo M, Johnson JA and Surh YJ (2007) Inhibitory effects of 7-carboxymethyloxy-3′,4′,5-trimethoxy flavone (DA-6034) on Helicobacter pylori-induced NF-kB activation and iNOS expression in AGS cells.Annals of New York Academy of Sciences 1095 527-535
Lee JS, Kim IH and Kim SY (2006) Changes in gene expression with increased transglutaminase 2 in a SH-SY5Y cell line. Frontiers in Bioscience 11 2774-2781
Lee JS, Kim SG, Kim HK, Lee TH, Jeong YI, Lee CM, Yoon MS, Na YJ, Suh DS, Park NC, Choi IH, Kim GY, Choi YH, Chung HY and Park YM (2006) Silibinin polarizes Th1/Th2 immune responses through the inhibition of immunostimulatory function of dendritic cells. Journal of Cellular Physiology 210 385-397
Lee JS, Lee JC, Lee CM, Jung ID, Jeong YI, Seong EY, Chung HY and Park YM (2007) Outer membrane protein A of Acinetobacter baumannii induces differentiation of CD4(+) T cells toward a Th1 polarizing phenotype through the activation of dendritic cells. Biochemical Pharmacology 74 86-97
Lee JS, Lee Jy, Son JW, Oh JH, Shin DM, Yuk JM, Song CH, Paik TH and Jo EK (2008) Expression and regulation of the CC-chemokine ligand 20 during human tuberculosis. Scandinavian Journal of Immunology 67 77-85
Lee JS, Nauseef WM, Moeenrezakhanlou A, Sly LM, Noubir S, Leidal KG, Schlomann JM, Krystal G and Treiner NE (2007) Monocyte p110a phosphatidylinositol 3-kinase regulates phagocytosis, the phagocyte oxidase, and cytokine production.
Journal of Leukocyte Biology 81 1548-1561
Lee JS, Oh TY, Ahn BO, Cho H, Kim WB, Kim YB, Surh YJ, Kim HJ and Hahm KB (2001) Involvement of oxidative stress in experimentally induced reflux esophagitis and Barrett’s esophagus: clue for the chemoprevention of esophageal carcinoma by antioxidants. Mutation Research 480-481 189-200
Lee JS, Ryu CH, Moon NH, Kim SJ, Park SY and Suh KT (2008) Changes in serum levels of receptor activator of nuclear factor-kB ligand, osteoprotegerin, IL-6 and TNF-a in patients with a concomitant head injury and fracture. Arch Orthop Trauma Surg in press
Lee JW, Lee MS, Kim TH, Lee HJ, Hong SS, NOh YH, Hwang BY, Ro JS and Hong JT (2007) Inhibitory effect of inflexinol on nitric oxide generation and iNOS expression via inhibition of NF-kB activation. Mediators of Inflammation 2007 93148
Lee JY, Huerta-Yepez S, Vega M, Baritaki S, Spandidos DA and Bonadvida B (2007) The NO TRAIL to YES TRAIL in cancer therapy.
International Journal of Oncology 31 685-691
Lee JY, Je JH, Jung KJ, Yu BP and Chung HY (2004) Induction of endothelial iNOS by 4-hydroxyhexenal through NF-kB activation. Free Radical Biology and Medicine 37 539-548
Lee JY, Jhun BS, Oh YT, Lee JH, Choe W, Baik HH, Ha J, Yoon KS, Kim SS and Kang I (2005) Activation of adenosine A(3) receptor suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of PI 3-kinase/Akt and NF-kappaB activation in murine BV2 microglial cells. Neuroscience Letters in press
Lee JY, Kim JS, Kim JM, Kim N, Jung HC and Song IS (2007) Simvastatin inhibits NF-kB signaling in intestinal epithelial cells and ameliorates acute murine colitis. International Immunopharmacology 7 241-248
Lee JY, Kim JY, Lee YG, GRhee MH, Hong EK and Cho JY (2008) Molecular mechanism of macrophage activation by exopolysaccharides from liquid culture of Lentinus edodes. Journal of Microbiology & Biotechnology 18 355-364
Lee JY, Moon SK, Hwang CW, Nam KS, Kim YK, Yoon HD, Kim MG and Kim CH (2005) A novel function of benzyl isothiocyanate in vascular smooth muscle cells: The role of ERK1/2, cell cycle regulation, and matrix metalloproteinase-9. Journal of Cell Physiology 203 493-500
Lee JY, Plakidas A, Lee WH, Heikkinen A, Chanmugam P, Bray G and Hwang DH (2003) Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids. Journal of Lipid Research 44 479-486
Lee JY, Rhee MH and Cho JY (2008)Novel modulatory effects of SDZ 62-434 on inflammatory events in activated macrophage-like and monocytic cells. Naunyn Schmiedebergs Arch Pharmacol in press
Lee JY, Shin JW, Chun KS, Park KK, Chung WY, Bang YJ, Sung JH and Surh YJ (2004) Anti-tumor promotional effects of a novel intestinal bacterial metabolite (IH-901) derived from the protopanaxadiol type ginsenosides in mouse skin. Carcinogenesis 26 359-367
Lee JY, Woo ER and Kang KW (2005) Inhibition of lipopolysaccharide-inducible nitric oxide synthase expression by acteoside through blocking of AP-1 activation. Journal of Ethnopharmacology 9 561-566
Lee JY, Ye J, Gao Z, Youn HS, Lee WH, Zhao L, Sizemore N and Hwang DH (2003) Reciprocal modulation of TLR4-signaling pathways involving MyD88 and PI3K/AKT by saturated and polyunsaturated fatty acids. Journal of Biological Chemistry 278 37041-37051
Lee JY, Yu BP and Chung HY (2005) Activation mechanisms of endothelial NF-kB, IKK, and MAP kinase by tert-butyl hydroperoxide. Free Radicical Research 39 399-409
Lee JY, Zhao L, Youn HS, Weatherill AR, Tapping R, Feng L, Lee WH, Fitzgerald K and Hwang DH (2004) Saturated fatty acid activates but polyunsaturated fatty acid inhibits toll-like receptor 2 dimerized with toll-like receptor 6 or 1. Journal of Biological Chemistry 279 16971-16979
Lee K, Burgoon LD, Lamb L, Dere E, Zacharewski TR, Hogenesch JB and Lapres JJ (2006) Identification and characterization of genes susceptible to transcriptional cross-talk between the hypoxia and dioxin signaling cascades.Chemical Research and Toxicology 19 1284-1293
Lee KA, Cho KJ, Kim SH, Shim JH, Lim JS, Cho DH, Song MS, Dinarello CA and Yoon DY (2005) IL-18 E42A mutant is resistant to the inhibitory effects of HPV-16 E6 and E7 oncogenes on the IL-18-mediated immune response. Cancer Letters 229 261-270
Lee KE, Kim JW, Jeong KY, Kim KE, Yong TS and Sohn MH (2007) Regulation of German cockroach extract-induced IL-8 expression in human airway epithelial cells. Clinical and Experimental Allergy 37 1364-1373
Lee KH, Feig C, Tchikov V, Schickel R, Hallas C, Schutze S, Peter ME and Chan AC (2006) The role of receptor internalization in CD95 signaling. EMBO Journal 25 1009-1023
Lee KH, Hwang YH, Lee CT, Kim YW, Han SK, Shim YS and Yoo CG (2004) The heat-shock-induced suppression of the IkB/NF-kB cascade is due to inactivation of upstream regulators of IkBa through insolubilization. Experimental Cell Research 299 49-56
Lee KH, Lee CT, Kim YW, Han SK, Shim YS and Yoo CG (2005) Heat shock protein 70 negatively regulates the heat-shock-induced suppression of the IkB/NF-kB cascade by facilitating IkB kinase renaturation and blocking its further denaturation.Experimental Cell Research 307 276-284
Lee KH, Yun SJ, Nam KN, Gho YS and Lee Eh (2007) Activation of microglial cells by ceruloplasmin. Brain Research in press
Lee KJ, Hwang SJ, Choi JH and Jeong HG (2008) Saponins derived from the roots of Platycodon grandiflorum inhibit HT-1080 cell invasion and MMPs activities: Regulation of NF-kB activation via ROS signal pathway. Cancer Letters in press
Lee KJ, Kim YM, Kim DY, Jeoung D, Han K, Lee ST, Lee YS, Park KH, Park JH, Kim DJ and Hahn JH (2006) Release of heat shock protein 70 (Hsp70) and the effects of extracellular Hsp70 on matric metalloproteinase-9 expression in human monocytic U937 cells. Experimental Molecular Medicine 38 364-374
Lee KK, Kwong WH, Chau FT, Yew DT and Chan WY (2002) Pien Tze Huang protects the liver against carbon tetrachloride-induced damage. Pharmacology and Toxicology 91 185-192
Lee KM, Kang NJ, Han JH, Lee KW and Lee HJ (2007) Myricetin down-regulates phorbol ester-induced cyclooxygenase-2 expression in mouse epidermal cells by blocking activation of nuclear factor kB. Journal of Agriculture and Food Chemistry in press
Lee KM, Kang BS, Lee HL, Son SJ, Hwang SH, Kim DS, Park JS and Cho HJ (2004) Spinal NF-kB activation induces COX-2 upregulation and contributes to inflammatory pain hypersensitivity. European Journal of Neuroscience 19 3375-3381
Lee KM, Park KG, Kim YD, Lee HJ, Kim HT, Cho WH, Kim HS, Han SW, Koh GY, Park JY, Lee KU, Kim JG and Lee IK (2006) Alpha-lipoic acid inhibits fractalkine expression and prevents neointimal hyperplasia after balloon injury in rat carotid artery.
Atherosclerosis 189 106-114
Lee KM, Yeo M, Choue JS, Jin JH, Park SJ, Cheong JY, Lee KJ, Kim JH and Hahm KB (2004) Protective mechanism of epigallocatechin-3-gallate against Helicobacter pylori-induced Ggastric epithelial cytotoxicity via the blockage of TLR-4 signaling. Heliobacter 9 632-642
Lee KS, Kim SR, Park SJ, Min KH, Lee KY, Jin SM, Yoo WH and Lee YC (2006) Antioxidant down-regulates IL-18 expression in asthma.
Molecular Pharmacology 70 1184-1193
Lee KS, Lee SJ, Park HJ, Chung JP, Han KH, Chon CY, Lee SI and Moon YM (2001) Oxidative stress effect on the activation of hepatic stellate cells. Yonsei Medical Journal 42 1-8
Lee KS, Park SJ, Kim SR, Min KH, Jin SM, Lee HK and Lee YC (2006) Modulation of airway remodeling and airway inflammation by peroxisome proliferator-activated receptor gamma in a murine model of toluene diisocyanate-induced asthma. Journal of Immunology 177 5248-5257
Lee KS, Park JH, Lee S, Lim HJ, Choi HE and Park HY (2007) HB-EGF induces delayed STAT3 activation via NF-kB mediated IL-6 secretion in vascular smooth muscle cell. Biochimica et Biophysica Acta in press
Lee KS, Kim SR, Park HS, Park SJ, Min KH, Lee KY, Choe YH, Hong SH, Han HJ, Lee YR, Kim JS, Atlas D and Lee YC (2007) A novel thiol compound, N-acetylcysteine amide, attenuates allergic airway disease by regulating activation of NF-kB and hypoxia-inducible factor-1a. Experimental and Molecular Medicine 39 756-768
Lee KS, Park HS, Park SJ, Kim SR, Min KH, Jin SM, Li L and Lee YC (2006) An antioxidant modulates expression of receptor activator of NF-kB in asthma.Experimental and Molecular Medicine 38 217-229
Lee KU, Lee IK, Han J, Song DK, Kim YM, Song HS, Kim HS, Lee WJ, Koh EH, Song KH, Han SM, Kim MS, Park IS and Park JY (2005) Effects of recombinant adenovirus-mediated uncoupling protein 2 overexpression on endothelial function and apoptosis. Circulation Research 96 1200-1207
Lee KW, Chun KS, Lee JS, Kang KS, Surh YJ and Lee HJ (2004) Inhibition of cyclooxygenase-2 expression and restoration of gap junction intercellular communication in H-ras-transformed rat liver epithelial cells by caffeic acid phenethyl ester. Annals of the New York Academy of Sciences 1030 501-507
Lee KW, Jung J, Lee Y, Kim TY, Choi SY, Park J, Kim DS and Kwon HJ (2006) Immunostimulatory oligodeoxynucleotide isolated from genome wide screening of Mycobacterium bovis chromosomal DNA. Molecular Immunology 43 2107-2118
Lee KW, Kang NJ, Heo YS, Rogozin EA, Pugliese A, Hwang MK, Bowden GT, Bode AM, Lee HJ and Dong Z (2008) Raf and MEK protein kinases are direct molecular targets for the chemopreventive effect of quercetin, a major flavonol in red wine. Cancer Research 68 946-955
Lee KW, Kim DS, Kwon HJCG sequence- and phosphorothioate backbone modification-dependent activation of the NF-kB-responsive gene expression by CpG-oligodeoxynucleotides in human RPMI 8226 B cells. Molecular Immunology 41 955-964
Lee KW, Kim JH, Lee HJ and Surh Aj (2005) Curcumin inhibits phorbol ester-induced up-regulation of cyclooxygenase-2 and matrix metalloproteinase-9 by blocking ERK1/2 phosphorylation and NF-kB transcriptional activity in MCF10A human breast epithelial cells. Antioxidants and Redox Signaling 7 1612-1620
Lee KW, Kim MS, Kang NJ, Kim DH, Surh YJ, Lee HJ and Moon A (2006) H-Ras selectively up-regulates MMP-9 and COX-2 through activation of ERK1/2 and NF-kB: An implication for invasive phenotype in rat liver epithelial cells.International Journal of Cancer 119 1767-1775
Lee KW, Kundu JK, Kim SO, Chun KS, Lee HJ and Surh YJ (2006) Cocoa polyphenols inhibit phorbol ester-induced superoxide anion formation in cultured HL-60 cells and expression of cyclooxygenase-2 and activation of NF-kB and MAPKs in mouse skin in vivo. Journal of Nutrition 136 1150-1155
Lee KW, Lee Y, Kim DS and Kwon HJ (2006) Direct role of NF-kB activation in Toll-like receptor-triggered HLA-DRA expression.
European Journal of Immunology 36 1254-1266
Lee KW, Lee Y, Kwon HJ, Kim DS (2005) Sp1-associated activation of macrophage inflammatory protein-2 promoter by CpG-oligodeoxynucleotide and lipopolysaccharide. Cell Mol Life Sci 62 188-198
Lee KY, Chang W, Qiu D, Kao PN and Rosen GD (1999) PG490 (triptolide) cooperates with tumor necrosis factor-alpha to induce apoptosis in tumor cells. Journal of Biological Chemistry 274 13451-13455
Lee KY, D’Acquisto F, Hayden MS, Shim JH and Ghosh S (2005) PDK1 nucleates T cell receptor-induced signaling complex for NF-kB activation. Science 308 114-118
Lee KY, Ho SC, Lin HC, Lin SM, Liu CY, Huang CD, Wang CH, CHung KF and Kuo HP (2006) Neutrophil-derived elastase induces TGF-beta1 secretion in human airway smooth muscle via NF-kB pathway. American Journal of Respiratory Cell and Molecular Biology 35 407-414
Lee KY, Ito K, Hayashi R, Jazrawi EP, Barnes PJ and Adcock IM (2006) NF-kB and activator protein 1 response elements and the role of histone modifications in IL-1b-induced TGF-b1 gene transcription. Journal of Immunology 176 603-615
Lee KY and Jeon YJ (2003) Polysaccharide isolated from Poria cocos sclerotium induces NF-kB/Rel activation and iNOS expression in murine macrophages. International Immunopharmacology 3 1353-1362
Lee KY, Jeon YJ (2005) Macrophage activation by polysaccharide isolated from Astragalus membranaceus. International Immunopharmacology 5 1225-1233
Lee KY, Lee MH, Chang IY, Yoon SP, Lim DY and Jeon YJ (2006) Macrophage activation by polysaccharide fraction isolated from Salicornia herbacea. Journal of Ethnopharmacology 103 372-378
Lee KY, You HJ, Jeong HG, Kang JS, Kim HM, Rhee SD and Jeon YJ (2004) Polysaccharide isolated from Poria cocos sclerotium induces NF-kB/Rel activation and iNOS expression through the activation of p38 kinase in murine macrophages. International Immunopharmacology 4 1029-1038
Lee LF, Lih CJ, Huang CJ, Cao T, Cohen SN and McDevitt HO (2008) Genomic expression profiling of TNF-a-treated BDC2.5 diabetogenic CD4+ T cells. Proceedings of the National Academic of Sciences USA in press
Lee M and Jeon YJ (2001) Paclitaxel-induced immune suppression is associated with NF-kB activation via conventional PKC isotypes in lipopolysaccharide- stimulated 70Z/3 pre-B lymphocyte tumor cells. Molecular Pharmacology 59 248-253
Lee M, Kim JY and Koh WS (2004) Apoptotic effect of PP2 a Src tyrosine kinase inhibitor, in murine B cell leukemia. Journal of Cellular Biochemistry 93 629
Lee M and Koh WS (2003) Raf-independent and MEKK1-dependent activation of NF-kB by hydrogen peroxide in 70Z/3 pre-B lymphocyte tumor cells. Journal of Cellular Biochemistry 88 545-556
Lee M and Yang KH (2000) 2-Acetylaminofluorene suppresses immune response through the inhibition of nuclear factor-kB activation during the early stage of B cell development. Toxicology Letters 114 173-180
Lee MH, Kim JY, Yoon JH, Lim HJ, Kim TH, Jin C, Kwak WJ, Han Ck and Ryu JH (2006) Inhibition of nitric oxide synthase expression in activated microglia and peroxynitrite scavenging activity by Opuntia ficus indica var. saboten.Phytotherapy Research 20 742-747
Lee MH, Lee JM, Jun SH, Ha CG, Lee SH, Kim NW, Lee JH, Ko NY, Mun SH, Park SH, Kim BK, Her E, KIm YM and Choi WS (2007) In-vitro and in-vivo anti-inflammatory action of the ethanol extract of Trachelospermi caulis. Journal of Pharmacy andPharmacology 59 123-130
Lee MH, Lee JM, Jun SH, Lee SH, Kim NW, Lee JH, Ko NY, Mun SH, Kim BK, Lim BO, Choi DK and Choi WS (2007) The anti-inflammatory effects of Pyrolae herba extract through the inhibition of the expression of inducible nitric oxide synthase (iNOS) and NO production. Journal of Ethnopharmacology in press
Lee MH, Song HK, Ko GJ, Kang YS, Han SY, Han KH, Kim HK, Han JY and Cha Dr (2008) Angiotensin receptor blockers improve insulin resistance in type 2 diabetic rats by modulating adipose tissue. Kindey International in press
Lee MJ, Hsu JD, Lin CL, Lin MH, Yuan SC and Wang CJ (2002) Induction of epidermal proliferation and expressions of PKC and NF-kB by betel quid extracts in mouse: the role of lime-piper additives in betel quid. Chemico-Biological Interactions 140 35-48
Lee MJ, Kim MJ, Song YS, SOng YO and Moon GS (2008) Bamboo culm extract supplementation elevates HDL-cholesterol and ameliorates oxidative stress in C57BL/6 mice fed atherogenic diet. Journal of Medicine and Food 11 69-77
Lee MJ, Park WH, Song YS, Lee YW, Song YO and Moon GS (2008) Effect of bamboo culm extract on oxidative stress and genetic expression: Bamboo culm extract ameliorates cell adhesion molecule expression and NFkB activity through the suppression of the oxidative stress. Clinical Nutrition in press
Lee MJ, Yang CW, Jin DC, Chang YS, Bang BK and Kim YS (2003) Bone morphogenetic protein-7 inhibits constitutive and interleukin-1beta-induced monocyte chemoattractant protein-1 expression in human mesangial cells: role for JNK/AP-1 pathway. Journal of Immunology 170 2557-2563
Lee MS, Chang I and Kim S (2004) Death effectors of beta-cell apoptosis in type 1 diabetes. Molecular Genetics and Metabolism 83 82-92
Lee MS and Kim YJ (2007) Signaling pathways downstream of pattern-recognition receptors and their cross talk. Annual Review of Biochemistry in press
Lee MY, Heo JS and Han HJ (2006) Dopamine regulates cell cycle regulatory proteins via cAMP, Ca(2+)/PKC, MAPKs, and NF-kB in mouse embryonic stem cells. Journal of Cellular Physiology 208 399-406
Lee MY, Jung SVC, Lee JH and Han HJ (2008) Estradiol-17beta protects against hypoxia-induced hepatocyte injury through ER-mediated upregulation of Bcl-2 as well as ER-independent antioxidant effects. Cell Research 18 491-499
Lee MY, Kim WJ, Kang YJ, Jung YM, Kang YM, Suk K, Park JE, Choi EM, Choi BKJ, Kwon BS and Lee WH (2006) Z39Ig is expressed on macrophages and may mediate inflammatory reactions in arthritis and atherosclerosis. Journal of LeukoctyeBiology 80 922-928
Lee NK, Choi HK, Kim DK and Lee SY (2006) Rac1 GTPase regulates osteoclast differentiation through TRANCE-induced NF-kB activation. Molecular and Cellular Biochemistry 281 55-61
Lee NK, Choi YG, Baik JY, Han SY, Jeong DW, Bae YS, Kim N and Lee SY (2005) A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation. Blood 106 852-859
Lee NK and Lee SY (2002) Modulation of life and death by the tumor necrosis factor receptor-associated factors (TRAFs). Journal of Biochemistry and Molecular Biology 35 61-66
Lee NP, Leung KW, Wo JY, Tam PC, Yeung WS and Luk JM (2006) NF-kB signaling blockade by Bay 11-7085 during early cardiac morphogenesis induces alterations of the outflow tract in chicken heart. Apoptosis 11 1215-1229
Lee PY, Tsai PS, Huang YH and Huang CJ (2008) Inhibition of Toll-like receptor-4, nuclear factor-kB and mitogen activation protein kinase by lignocaine may involve voltage-sensitive sodium channels. Clincal and Experimental Pharmacology and Physiology in press
Lee R and Collins T (2001) Nuclear factor-kB and cell survival: IAPs call for support. Circulation Research 88 262-264
Lee R, Beauparlant P, Elford H, Ponka P and Hiscott J (1997) Selective inhibition of IkBa phosphorylation and HIV-1 LTR-directed gene expression by novel antioxidant compounds. Virology 234 277-290
Lee R-m, Gillet G, Brunside J, Thomas SJ and Neiman P (1999) Role of Nr13 in regulation of programmed cell death in the bursa of Fabricius. Genes & Development 13 718-728
Lee S, Andrieu C, Saltel F, Destaing O, Auclair J, Pouchkine V, Michelon J, Salaun B, Kobayashi R, Jurdic P, Kieff ED and Sylla BS (2004) IkB kinase beta phosphorylates Dok1 serines in response to TNF, IL-1, or gamma radiation. Proceedings of the National Academy of Sciences USA 101 17416-17421
Lee S, Chung J, Ha IS, Yi K, Lee JE, Kang HG, Choi I, Oh KH, Kim JY, Surh Cd and Ahn C (2007) Hydrogen peroxide increases human leukocyte adhesion to porcine aortic endothelial cells via NFkB-dependent up-regulation of VCAM-1. International Immunology in press
Lee S, Hong J, Choi SY, Oh SB, Park K, Kim JS, Karin M and Lee SJ (2004) CpG oligodeoxynucleotides induce expression of proinflammatory cytokines and chemokines in astrocytes: the role of c-Jun N-terminal kinase in CpG ODN-mediated NF-kB activation. Journal of Neuroimmunology 153 50-63
Lee S, Kim W, Kang KP, Moon SO, Sung MJ, Kim DH, Kim HJ and Park SK (2005) Agonist of peroxisome proliferator-activated receptor-{gamma}, rosiglitazone, reduces renal injury and dysfunction in a murine sepsis model. Nephrology, Dialysis, Transplantation 20 1057-1065
Lee S, Kim W, Moon SO, Sung MJ, Kim DH, Kang KP, Jang KY, Lee SY, Park BH, Koh GY and Park SK (2006) Renoprotective effect of COMP-angiopoietin-1 in db/db mice with type 2 diabetes. Nephrology, Dialysis & Transplantation in press
Lee S, Lee M and Kim SH (2008) Eupatilin inhibits H(2)O(2)-induced apoptotic cell death through inhibition of mitogen-activated protein kinases and nuclear factor-kB. Food Chemistry and Toxicology in press
Lee S, Moon SO, Kim W, Sung MJ, Kim DH, Kang KP, Jang YB, Lee JE, Jang KY, Lee SY and Park SK (2006) Protective role of L-2-oxothiazolidine-4-carboxylic acid in cisplatin-induced renal injury. Nephrology, Dialysis, Transplantation 21 2085-2095
Lee S, Park HH, Son HY, Ha JH, Lee MG, Oh TY, Sohn DH, Jeong TC, Lee SH, Son JK, Lee SG, Jun CD and Kim SH (2006) DA-9601 inhibits activation of the human mast cell line HMC-1 through inhibition of NF-kB. Cell Biology and Toxicology in press
Lee S and Rivier C (2005) Role played by hypothalamic NF-kB in alcohol-mediated activation of the rat hypothalamic-pituitary-adrenal axis. Endocrinology 146 2006-2014
Lee S, Kim W, Moon SO, Sung MJ, Kim DH, Kang KP, Jang YB, Lee JE, Jang KY and Park SK (2006) Rosiglitazone ameliorates cisplatin-induced renal injury in mice.Nephrology, Dialysis, Transplantation 21 2096-2105
Lee S, Oh HM, Lim WB, CHou EJ, Park YN, Kim JA, Choi JY, HOng SJ, Oh HK, Son JK, Lee SH, Kim OJ, Choi HR and Jun CD (2008) Gene induction by glycyrol to apoptosis through endonuclease G in tumor cells and prediction of oncogene function by microarray analysis. Anticancer Drugs 19 503-515
Lee S, Suk K, Kim IK, Jang IS, Park JW, Johnson VJ, Kwon TK, Choi BJ and Kim SH (2008) Signaling pathways of bisphenol A-induced apoptosis in hippocampal neuronal cells: Role of calcium-induced reactive oxygen species, mitogen-activated protein kinases, and nuclear factor-kB. Journal of Neuroscience Research in press
Lee SA, Fitzgerald SM, Huang SK, Li C, Chi DS and Krishnaswamy G (2004) Molecular regulation of IL-13 and MCP-1 expression in human mast cells by IL-1beta. American Journal of Respiratory Cell and Molecular Biology 31 283-291
Lee SA, Park SH and Kim BC (2008) Raloxifene, a selective estrogen receptor modulator, inhibits lipopolysaccharide-induced nitric oxide production by inhibiting the phosphatidylinositol 3-kinase/Akt/nuclear factor-kB pathway in RAW264.7 macrophage cells. Molecules and Cells in press
Lee SB, Hong SH, Kim H and Um HD (2005) Co-induction of cell death and survival pathways by phosphoinositide 3-kinase. Life Sciences 78 91-98
Lee SB, Park J, Jung JU and Chung J (2005) Nef induces apoptosis by activating JNK signaling pathway and inhibits NF-kB-dependent immune responses in Drosophila. Journal of Cell Science 118 1851-1859
Lee SB and Schorey JS (2005) Activation and mitogen-activated protein kinase regulation of transcription factors Ets and NF-kB in Mycobacterium-infected macrophages and role of these factors in tumor necrosis factor alpha and nitric oxide Synthase 2 promoter function. Infection and Immunity 73 6499-6507
Lee SE, Kim SY, Jeong BC, Kim YR, Bae SJ, Ahn OS, Lee JJ, Song HC, Kim JM, Choy HE, Chung SS, Kweon MN and Rhee JH (2006) A bacterial flagellin, Vibrio vulnificus FlaB, has a strong mucosal adjuvant activity to induce protective immunity.
Infection and Immunity 74 694-702
Lee SG, Choi JK, Choi BH, Lim Y, Kim YH, Lee KH, Shin JC and Ahn WS (2006) The effect of adenosine 5′-triphosphate on calcium mobilization and cell proliferation in cervical cancer cells. European Journal of Obstettics, Gynecology, and Reproductive Biology 127 110-114
Lee SH, Chung YH, Cho NH, Gwack Y, Feng P and Jung JU (2004) Modulation of T-cell receptor signal transduction by herpesvirus signaling adaptor protein. Molecular and Cellular Biology 24 5369-5382
Lee SH and Hannink M (2002) Identification of nuclear import and export functions of IkBe. Journal of Biological Chemistry 277 23358-23366
Lee SH and Hannink M (2002) The N-terminal nuclear export sequence of IkBa is required for RanGTP-dependent binding to CRM1. Journal of Biological Chemistry 276 23599-23606
Lee SH, Heo JS, Lee MY and Han HJ (2008) Effect of dihydrotestosterone on hydrogen peroxide-induced apoptosis of mouse embryonic stem cells. Journal of Cell Physiology in press
Lee SH, Kim KK and Choi BK (2005) Upregulation of intercellular adhesion molecule 1 and proinflammatory cytokines by the major surface proteins of Treponema maltophilum and Treponema lecithinolyticum, the phylogenetic group IV oral spirochetes associated with periodontitis and eEndodontic infections. Infection and Immunity 73 168-176
Lee SH, Kim T, Park ES, Yang S, Jeong D, Choi Y and Rho J (2008) NHE10, a novel osteoclast-specific member of the Na(+)/H(+) exchanger family, regulates osteoclast differentiation and survival. Biochemical and Biophysical Research Communications in press
Lee SH, Lee CW, Lee JW, Choi MS, Son DJ, Chung YB, Lee CK, Oh KW, Moon DC, Kwon BM and Hong JT (2005) Induction of apoptotic cell death by 2′-hydroxycinnamaldehyde is involved with ERK-dependent inactivation of NF-kB in TNF-a-treated SW620 colon cancer cells. Biochemical Pharmacology 70 1147-1157
Lee SH, Lee SY, Son DJ, Lee H, Yoo HS, Song S, Oh KW, Han DC, Kwon BM and Hong JT (2005) Inhibitory effect of 2′-hydroxycinnamaldehyde on nitric oxide production through inhibition of NF-kB activation in RAW 264.7 cells.Biochemical Pharmacology 69 791-799
Lee SH and Lim KT (2007) UDN glycoprotein regulates activities of manganese-superoxide dismutase, activator protein-1, and nuclear factor-kB stimulated by reactive oxygen radicals in lipopolysaccharide-stimulated HCT-116 cells. Cancer Letters in press
Lee SH, Nishino M, Mazumdar T, Garcia GE, Galifione M, Lee FL, Lee CL, Liang A, Kim J, Feng L, Eissa NT, Lin SH and Yu-Lee LY (2005) 16-kDa prolactin down-regulates inducible nitric oxide synthase expression through inhibition of the signal transducer and activator of transcription 1/IFN regulatory factor-1 pathway. Cancer Research 65 7984-7992
Lee SH, Park HH, Kim JE, Kim JA, Kim YH, Jun CD and Kim SH (2007) Allose gallates suppress expression of pro-inflammatory cytokines through attenuation of NF-kB in human mast cells.
Planta Medica 73 769-773
Lee SH, Park SG, Lim SO and Jung G (2005) The hepatitis B virus X protein up-regulates lymphotoxin alpha expression in hepatocytes. Biochimica et Biophysica Acta 1741 75-84
Lee SH, Ryu JK, Lee KY, Woo SM, Park JK, Yoo JW, Kim YT and Yoon YB (2007) Enhanced anti-tumor effect of combination therapy with gemcitabine and apigenin in pancreatic cancer.
Cancer Letters in press
Lee SH, Seo GS, Ko G, Kim JB and Sohn DH (2005) Anti-inflammatory activity of 20(S)-protopanaxadiol: enhanced heme oxygenase 1 expression in RAW 264.7 cells.Planta Medica 71 1167-1170
Lee SH, Seo GS and Sohn DH (2004) Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase by butein in RAW 264.7 cells. Biochemical and Biophysical Research Communications 323 125-132
Lee SH, Seo MJ, Choi SM, Sohn YS, Kang KK, Ahn BO, Kwon JW and Yoo M (2005) DA-9201 shows anti-asthmatic effects by suppressing NF-kB expression in an ovalbumin-induced mouse model of asthma. Archives of Pharmacal Research 28 1350-1357
Lee SH, Sohn DH, Jin XY, Kim SW, CHoi SC and Seo GS (2007) 2′,4′,6′-Tris(methoxymethoxy) chalcone protects against trinitrobenzene sulfonic acid-induced colitis and blocks tumor necrosis factor-alpha-induced intestinal epithelial inflammation via heme oxygenase 1-dependent and independent pathways.Biochemical Pharmacology in press
Lee SH, Son SM, Son DJ, Kim SM, Kim TJ, Song S, Moon DC, Lee HW, Ryu JC, Yoon DY and Hong JT (2007) Epothilones induce human colon cancer SW620 cell apoptosis via the tubulin polymerization independent activation of the nuclear factor-kB/IkB kinase signal pathway. Molecular Cancer Therapeutics 6 2786-2797
Lee SH, Song R, Lee MN, Kim CS, Lee H, Kong YY, Kim H and Jang SK (2008) A molecular chaperone glucose-regulated protein 94 blocks apoptosis induced by virus infection. Hepatology in press
Lee SH, Stehlik C and Reed JC (2001) Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing. Journal of Biological Chemistry 276 34495-34500
Lee SJ, Bai SK, Lee KS, Namkoong S, Na HJ, Ha KS, Han JA, Yim SV, Chang K, Kwon YG, Lee SK and Kim YM (2003) Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing IkB kinase-dependent NF-kB activation. Molecules and Cells 16 97-105
Lee S-J, Dimtchev A, Lavin MF, Dritschilo A and Jung M (1998) A novel ionizing radiation-induced signaling pathway that activates the transcription factor NF-kB. Oncogene 17 1821-1826
Lee SJ, Heo KS, Oh PS, Lim K and Lim KT (2004) Glycoprotein isolated from Ulmus davidiana Nakai inhibits TPA-induced apoptosis through nuclear factor-kB in NIH/3T3 cells. Toxicology Letters 146 159-174
Lee SJ, Hou J and Benveniste EN (1998) Transcriptional regulation of intercellular adhesion molecule-1 in astrocytes involves NF-kB and C/EBP isoforms. Journal of Neuroimmunology 92 196-207
Lee SJ, Kim HM, Cho YH, Park K, Kim EJ, Jung KH, Kim CH, Kim WJ and Moon SK (2007) Aqueous extract of Magnolia officinalis mediates proliferative capacity, p21WAF1 expression and TNF-alpha-induced NF-kB activity in human urinary bladder cancer 5637 cells; involvement of p38 MAP kinase. Oncology Reports 18 729-736
Lee SJ and Lee S (2002) Toll-like receptors and inflammation in the CNS. Current Drug Targets in Inflammation and Allergy 1 181-191
Lee SJ and Lim KT (2006) 150kDa glycoprotein isolated from Solanum nigrum Linne stimulates caspase-3 activation and reduces inducible nitric oxide production in HCT-116 cells. Toxicology In Vitro 20 1088-1097
Lee SJ and Lim KT (2007) Glycoprotein isolated from Ulmus davidiana Nakai regulates expression of iNOS and COX-2 in vivo and in vitro. Food and Chemical Toxicology 45 990-1000
Lee SJ and Lim KT (2008) Inhibitory effect of 30-kDa phytoglycoprotein on expression of TNF-a and COX-2 via activation of PKCa and ERK 1/2 in LPS-stimulated RAW 264.7 cells. Molecular and Cellular Biochemistry in press
Lee SJ, Nam WD, Na HJ, Cho YL, Ha KS, Hwang JY, Lee H, Kim SO, Kwon YG and Kim YM (2008) CT20126, a novel immunosuppressant, prevents collagen-induced arthritis through the down-regulation of inflammatory gene expression by inhibiting NF-kB activation. Biochemical Pharmacology in press
Lee SJ, Bae SS, Kim KH, Lee WS, Rhim BY, Hong KW and Kim CD (2007) High glucose enhances MMP-2 production in adventitial fibroblasts via Akt1-dependent NF-kB pathway. FEBS Letters 581 4189-4194
Lee SJ, Bae S, Seomun Y, Son MJ and Joo CK (2008) The role of nuclear factor kB in lens epithelial cell proliferation using a capsular bag model. Opthalmic Research in press
Lee SJ and Lim KT (2008) Cell death signal by glycine- and proline-rich plant glycoprotein is transferred from cytochrome c and nuclear factor kB to caspase 3 in Hep3B cells. Journal of Nutritional Biochemistry 19 166-174
Lee SJ and Lim KT (2007) Inhibitory effect of phytoglycoprotein on tumor necrosis factor-alpha and interleukin-6 at initiation stage of colon cancer in 1,2-dimethylhydrazine-treated ICR mice. Toxicology and Applied Pharmacology 225 198-205
Lee SJ and Lim KT (2008) Chemopreventive effect of plant originated glycoprotein on colitis-mediated colorectal cancer in A/J mice. Journal of Biomedical Sciences 154 111-121
Lee SJ, Oh PS, Ko JH, Lim K and Lim KT (2004) A 150-kDa glycoprotein isolated from Solanum nigrum L. has cytotoxic and apoptotic effects by inhibiting the effects of protein kinase C alpha, nuclear factor-kB and inducible nitric oxide in HCT-116 cells. Cancer Chemotherapy and Pharmacology 54 562-572
Lee SJ, Oh PS, Ko JH, Lim K and Lim KT (2006) Protective effect of glycoprotein isolated from Ulmus davidiana Nakai on carbon tetrachloride-induced mouse liver injury. Journal of Pharmacy and Pharmacology 58 143-152
Lee SJ, Park JY, Hou J and Benveniste EN (1999) Transcriptional regulation of the intercellular adhesion molecule-1 gene by proinflammatory cytokines in human astrocytes. Glia 25 21-32
Lee SJ, Park SS, Cho YH, Park K, Kim EJ, Jung KH, Kim SK, Kim WJ and Moon SK (2008) Activation of matrix metalloproteinase-9 by TNF-a in human urinary bladder cancer HT1376 cells: The role of MAP kinase signaling pathways. Oncology Reports 19 1007-1013
Lee SJ, Qin H and Benveniste EN (2007) Simvastatin inhibits IFN-gamma-induced CD40 gene expression by suppressing STAT-1alpha. Journal of Leukocyte Biology in press
Lee SJ, Zhou T, Choi C, Wang Z and Benveniste EN (2000) Differential regulation and function of Fas expression on glial cells. Journal of Immunology 164 1277-1285
Lee SK and Lorenzo JA (1999) Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: correlation with osteoclast-like cell formation. Endocrinology 140 3552-3561
Lee SK, Kalinowski J, Jastrzebski S and Lorenzo JA (2002) 1,25 (OH)(2) vitamin D(3)-stimulated osteoclast formation in spleen-osteoblast cocultures is mediated in part by enhanced IL-1a and receptor activator of NF-kB ligand production in osteoblasts. Journal of Immunology 169 2374-2380
Lee SK, Kim CS, Yang WS, Kim SB, Park SK and Park JS (2002) Exogenous nitric oxide inhibits tumor necrosis factor-alpha- or interleukin-1-beta-induced monocyte chemoattractant protein-1 expression in human mesangial cells: role of IkB-alpha and cyclic GMP. Nephron 92 780-787
Lee SK, Kim YW, Chi SG, Joo YS and Kim HJ (2008) The effect of Saccharomyces boulardii on human colon cells and inflammation in rats with trinitrobenzene sulfonic acid-induced colitis. Dig Dis Sci in press
Lee SK, Kim JH, Lee YC, Cheong J and Lee JW (2000) Silencing mediator of retinoic acid and thyroid hormone receptors, as a novel transcriptional corepressor molecule of activating protein-1, nuclear factor-kB, and serum response factor. Journal of Biological Chemistry 275 12470-12474
Lee SK, Kim JH, Yang WS, Kim SB, Park SK and Park JS (2002) Exogenous nitric oxide inhibits VCAM-1 expression in human peritoneal mesothelial cells. role of cyclic GMP and NF-kB. Nephron 90 447-454
Lee SK, Pi SH, Kim SH, Min KS, Lee HJ, Chang HS, Kang KH, Kim HR, Shin HI, Lee SK and Kim EC (2007) Substance P regulates macrophage inflammatory protein 3alpha/chemokine C-C ligand 20 (CCL20) with heme oxygenase-1 in human periodontal ligament cells. Clinical and Experimental Immunology inp ress
Lee SK, Seo SH, Kim BS, Kim CD, Lee JH, Kang JS, Maeng PJ and Lim JS (2005) IFN-g regulates the expression of B7-H1 in dermal fibroblast cells. Journal of Dermatological Science in press
Lee SM, Hong Nga NT, Park MH, Kim KS, Cho KJ, Moon DC, Kim HY, Yoon do Y and Hong JT (2004) EPO receptor-mediated ERK kinase and NF-kB activation in erythropoietin-promoted differentiation of astrocytes. Biochemical and Biophysical Research Communications 320 1087-1095
Lee SM and Kleiboeker SB (2005) Porcine arterivirus activates the NF-kB pathway through IkB degradation. Virology 342 47-59
Lee SO, Chang YC, Whang K, Kim CH and Lee IS (2007) Role of NAD(P)H:quinone oxidoreductase 1 on tumor necrosis factor-a-induced migration of human vascular smooth muscle cells. Cardiovascular Research 76 331-339
Lee SO, Jeong YJ, Kim M, Kim Ch and Lee IS (2007) Suppression of PMA-induced tumor cell invasion by capillarisin via the inhibition of NF-kB-dependent MMP-9 expression. Biochemical and Biophysical Research Communications in press
Lee SO, Jeong YJ, Yu MH, Lee JW, Hwangbo MH, Kim CH and Lee IS (2006) Wogonin suppresses TNF-a-induced MMP-9 expression by blocking the NF-kB activation via MAPK signaling pathways in human aortic smooth muscle cells. Biochemical andBiophysical Research Communications 351 118-125
Lee SO, Lou W, Nadiminty N, Lin X and Gao AC (2005) Requirement for NF-kB in interleukin-4-induced androgen receptor activation in prostate cancer cells. Prostate 64 160-167
Lee SO, Pinder E, Chun JY, Lou W, Sun M and Gao AC (2008) Interleukin-4 stimulates androgen-independent growth in LNCaP human prostate cancer cells. Prostate 68 85-91
Lee SP, Youn SW, Cho HJ, Li L, Kim TY, Yook HS, Chung JW, Hur J, Yoon CH, Park KW, Oh BH, Park YB and Kim HS (2006) Integrin-linked kinase, a hypoxia-responsive molecule, controls postnatal vasculogenesis by recruitment of endothelial progenitor cells to ischemic tissue. Circulation 114 150-159
Lee ST, Chu K, Jung KH, Kim SJ, Kim DH, Kang KM, Hong NH, Kim JH, Ban JJ, Park HK, Kim SU, Park CG, Lee SK, Kim M and Roh JK (2007) Anti-inflammatory mechanism of intravascular neural stem cell transplantation in haemorrhagic stroke. Brain in press
Lee SU, Sin HK, Min YK and Kim SH (2008) Emodin accelerates osteoblast differentiation through phosphatidylinositol 3-kinase activation and bone morphogenetic protein-2 gene expression. International Immunopharmacology 8 741-747
Lee SW, Han SI, Kim HH and Lee ZH (2002) TAK1-dependent activation of AP-1 and c-Jun N-terminal kinase by receptor activator of NF-kB. Journal of Biochemistry and Molecular Biology 35 371-376
Lee SW, Kwak HB, Chung WJ, Cheong H, Kim HH and Lee ZH (2003) Participation of protein kinase c beta in osteoclast differentiation and function. Bone 32 217-227
Lee SY, Cherla RP and Tesh VL (2006) Simultaneous induction of apoptotic and survival signaling pathways in macrophage-like THP-1 cells by Shiga toxin 1.Infection and Immunity in press
Lee SY, Ha TY, Son DJ, Kim SR and Hong JT (2005) Effect of sesaminol glucosides on beta-amyloid-induced PC12 cell death through antioxidant mechanisms. Neuroscience Research 52 330-341
Lee SY, Kaufman DR, Mora AL, Santana A, Boothby M and Choi Y (1998) Stimulus-dependent synergism of the antiapoptotic tumor necrosis factor receptor-associated factor 2 (TRAF2) and nuclear factor kB pathways. Journal of Experimental Medicine 188 1381-1384
Lee SY, Lee HY, Kim SD, Jo SH, Shim JW, Lee HJ, Yun J and Bae YS (2008) Lysophosphatidylserine stimulates chemotactic migration in U87 human glioma cells. Biocehmical and Biophysical Research Communications in press
Lee SY, Lee JW, Lee H, Yoo HS, Yun YP, Oh KW, Ha TY and Hong JT (2005) Inhibitory effect of green tea extract on beta-amyloid-induced PC12 cell death by inhibition of the activation of NF-kB and ERK/p38 MAP kinase pathway through antioxidant mechanisms. Brain Research Molecular Brain Research 140 45-54
Lee SY, Lee SY, Kandala G, Liou M-L, Liou H-C and Choi Y (1996) CD30/TNF receptor-associated factor interaction: NF-kB activation and binding specificity. Proceedings of the National Academy of Sciences USA 93 9699-9703
Lee SY, Son DJ, Lee YK, Lee JW, Lee HJ, Yun YW, Ha TY and Hong JT (2006) Inhibitory effect of sesaminol glucosides on lipopolysaccharide-induced NF-kB activation and target gene expression in cultured rat astrocytes. NeuroscienceResearch 56 204-212
Lee SY, Yuk DY, SOng HS, Yoon DY, Jung JK, Moon DC, Lee BS and Hong JT (2008) Growth inhibitory effects of obovatol through induction of apoptotic cell death in prostate and colon cancer by blocking of NF-kB. European Journal of Pharmacology in press
Lee TH, Shank J, Cusson N and Kelliher MA (2004) The kinase activity of Rip 1 is not required for TNF-alpha-induced IKK or p38 MAP kinase activation or for the ubiquitination of Rip 1 by Traf 2. Journal of Biological Chemistry 279 33185-33191
Lee TL, Alba D, Baxendale V, Rennert OM and Chan WY (2006) Application of transcriptional and biological network analyses in mouse germ-cell transcriptomes. Genomics 88 18-33
Lee TL, Yeh J, Friedman J, Yan B, Yang X, Yeh NT, Van Waes C and Chen Z (2008) A signal network involving coactivated NF-kB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas. International Journal of Cancer in press
Lee TH, Tai DI, Cheng CJ, Sun CS, Lin CY, Sheu MJ, Lee WP, Peng CY, Wang AH and Tsai SL (2006) Enhanced nuclear factor-kB-associated Wnt-1 expression in hepatitis B- and C-related hepatocarcinogenesis: identification by functional proteomics. Journal of Biomedical Science 13 27-39
Lee TK, Poon RT, Wo JY, Ma S, Guan XY, Myers JN, Altevogt P and Yuen AP (2007) Lupeol suppresses cisplatin-induced nuclear factor-kB activation in head and neck squamous cell carcinoma and inhibits local invasion and nodal metastasis in an orthotopic nude mouse model. Cancer Research 67 8800-8809
Lee TL, Yang XP, Yan B, Friedman J, Duggal P, Bagain L, Dong G, Yeh NT, Wang J, Zhou J, Elkahloun A, Van Waes C and Chen Z (2007) A novel nuclear factor-kB gene signature is differentially expressed in head and neck squamous cell carcinomas in association with TP53 status. Clinical Cancer Research 13 5680-5691
Lee TS, Chang CC, Zhu Y and Shyy JY (2004) Simvastatin induces heme oxygenase-1. A novel mechanism of vessel protection. Circulation 110 1296-1302
Lee TS, Park KK, Cho HS, Choo YA and Hwang M (2007) Effects of bioactive ceramics on the pathogenesis of rat vascular smooth muscle cells treated with phorbol 12-myristate 13-acetate.
Journal of Material Science and Material Medcine in press
Lee UJ, Chooung SR, Prakash KV, Lee EJ, Lee MY, Kim YJ, Han CW and Choi YC (2007) Dual knockdown of p65 and p50 subunits of NF-kB by siRNA inhibits the induction of inflammatory cytokines and significantly enhance apoptosis in human primary synoviocytes treated with tumor necrosis factor-alpha. Molecular BiologyReports in press
Lee WI, Torgerson TR, Schumacher MJ, Yel L, Zhu Q and Ochs HD (2004) Molecular analysis of a large cohort of patients with the hyper IgM syndrome (HIGM). Blood 105 1881-1890
Lee WI, Zhu Q, Gambine E, Jin Y, Welcher AA and Ochs HD (2003) Inducible CO-stimulator molecule, a candidate gene for defective isotype switching, is normal in patients with hyper-IgM syndrome of unknown molecular diagnosis. Journal of Allergy and Clinical Immunology 112 958-964
Lee WJ (2008) Bacterial-modulated signaling pathways in gut homeostasis. Science Signaling 1 pe24
Lee WP, Tai DI, Tsai SL, Yeh CT, Chao Y, Lee SD and Hung MC (2003) Adenovirus type 5 E1A sensitizes hepatocellular carcinoma cells to gemcitabine. Cancer Research 63 6229-6236
Lee Y, Allport V, Sykes A, Lindstrom T, Slater D and Bennett P (2003) The effects of labour and of interleukin 1 beta upon the expression of nuclear factor kB related proteins in human amnion. Molecular Human Reproduction 9 213-218
Lee Y, Broxmeyer HE, Mantel C, Kwon HJ, Kim JW, Kim JS, Kwon D and Choe IS (2003) Synergistic activation of p70S6 kinase associated with stem cell factor in MO7e cells. Experimental Molecular Medicine 35 222-226
Lee Y, Huang H, Kim HJ, Park CK, Kim HH (2008) The phosphatidylinositol 3-kinase-mediated production of interferon-beta is critical for the lipopolysaccharaide inhibition of osteoclastogenesis. Life Sciences 83 369-376
Lee Y, Hyung SW, Jung HJ, Kim HJ, Staerk J, Constantinescu SN, chang EJ, Lee ZH, Lee SW and Kim HH (2007) The ubiquitin-mediated degradation of Jak1 modulates osteoclastogenesis by limiting interferon-{beta}-induced inhibitory signaling.Blood in press
Lee Y, Sohn WJ, Kim DS and Kwon HJ (2004) NF-kB- and c-Jun-dependent regulation of human cytomegalovirus immediate-early gene enhancer/promoter in response to lipopolysaccharide and bacterial CpG-oligodeoxynucleotides in macrophage cell line RAW 264.7. European Journal of Biochemistry 271 1094-1105
Lee YA, Kim YJ, Cho EJ and Yokozawa T (2007) Ameliorative effects of proanthocyanidin on oxidative stress and inflammation in Streptozotocin-induced diabetic rats.
Journal of Agricultural Food Chemistry in press
Lee YC, Lee KS, Park SJ, Park HS, Lim JS, Park KH, Im MJ, Choi IW, Lee HK and Kim UH (2004) Blockade of airway hyperresponsiveness and inflammation in a murine model of asthma by a prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid. FASEB Journal 18 1917-1919
Lee YJ, Choi HJ, Kang TW, Kim HO, Chung MJ and Park YM (2008) CBT-SL5, a bacteriocin from Enterococcus faecalis, suppresses the expression of interleukin-8 induced by propionibacterium acnes in cultured human of interleukin-8 induced by Propionibacterium acnes in cultured human keratinocytes. Journal of Microbiology and Biotechnology 18 1308-1316
Lee YJ and Han HJ (2005) Effect of adenosine triphosphate in renal ischemic injury: Involvement of NF-kB. Journal of Cell Physiology 204 792-799
Lee YJ and Han HJ (2007) Albumin-stimulated DNA synthesis is mediated by Ca2+/PKC as well as EGF receptor-dependent p44/42 MAPKs and NF-kB signal pathways in renal proximal tubule cells. American Journal of Physiology: Renal Physiology in press
Lee YJ, Heo JS, Suh HN, Lee MY and Han HJ (2007) Interleukin-6 stimulates 14C-alpha-methyl-D-glucopyranoside uptake in renal proximal tubule cells: Involvement of STAT3, PI3K/Akt, MAPKs, and NF-kB. American Journal ofPhysiology: Renal Physiology in press
Lee YJ, Kang DG, Kim JS adn Lee HS (2007) Lycopus lucidus inhibits high glucose-induced vascular inflammation in human umbilical vein endothelial cells. Vascular Pharmacology in press
Lee YJ, Kang IJ, Bunger R and Kang YH (2004) Enhanced survival effect of pyruvate correlates MAPK and NF-kB activation in hydrogen peroxide-treated human endothelial cells. Journal of Applied Physiology 96 793-801
Lee YJ, Kang DG, Kim JS and Lee HS (2008) Effect of Buddleja officinalis on high glucose-induced vascular inflammation in human umbilical vein endothelial cells. Experimental Biology and Medicine in press
Lee Y-M, Miau L-H, Chang C-J and Lee S-C (1996) Transcriptional induction of the alpha-1 acid glycoportein (AGP) gene by synergistic interaction of two alternative activator forms of AGP/enhancer-binding protein (C/EBPb) and NF-kB or Nopp140. Molecular and Cellular Biology 16 4257-4263
Lee Ym Seong MJ, Lee JW, Lee YK, Kim TM, Nam SY, Kim DJ, Yun YW, Kim TS, Han SY and Hong JT (2007) Estrogen receptor independent neurotoxic mechanism of bisphenol A, an environmental estrogen. Journal of Veterinary Science 8 27-38
Lee YR, Lee JH, Noh EM, Kim EK, Song MY, Jung WS, Park SJ, Kim JS, Park JW, Kwon KB and Park BH (2008) Guggulsterone blocks IL-1b-mediated inflammatory responses by suppressing NF-kB activation in fibroblast-like synoviocytes. Life Sciences in press
Lee YR, Shim HJ, Yu HN, Song EK, Park J, Kwon KB, Park JW, Rho HW, Park BH, Han MK and Kim JS (2005) Dimethylsulfoxide induces upregulation of tumor suppressor protein PTEN through nuclear factor-kB activation in HL-60 cells. Leukemia Research 29 401-405
Lee YR, Su CY, Chow NH, Lai WW, Lei HY, Chang CL, Chang TY, Chen SH, Lin YS, Yeh Tm and Liu HS (2007) Dengue viruses can infect human primary lung epithelia as well as lung carcinoma cells, and can also induce the secretion of IL-6 and RANTES. Virus Research in press
Lee YR, Yu HN, Noh EM, Youn HJ, SOng EK, Han MK, Park CS, Kim BS, Park YS, Park BK, Lee SH and Kim JS (2007) TNF-a upregulates PTEN via NF-kB signaling pathways in human leukemic cells. Experimental & Molecular Medicine 39 121-127
Lee YS, Kang YS, Lee JS, Nicolova S and Kim JA (2004) Involvement of NADPH oxidase-mediated generation of reactive oxygen species in the apototic cell death by capsaicin in HepG2 human hepatoma cells. Free Radical Research 38 405-412
Lee YS, Song YS, Giffard RG and Chan PH (2006) Biphasic role of nuclear factor-kB on cell survival and COX-2 expression in SOD1 Tg astrocytes after oxygen glucose deprivation. Journal of Cerebral Blood Flow and Metabolism in press
Lee YS, Terzidou V, Lindstrom T, Johnson M and Bennett PR (2006) The role of CCAAT/enhancer-binding protein beta in the transcriptional regulation of COX-2 in human amnion. Molecular Human Reproduction in press
Lee YW, Eum SY, Nath A and Toborek M (2004) Estrogen-mediated protection against HIV Tat protein-induced inflammatory pathways in human vascular endothelial cells. Cardiovascular Research 63 139-148
Lee YW, Han SH, Suh JH, Jeon YJ and Yang KH (1998) Down-regulation of protein kinase C: a potential mechanism for 2-amino-3-methylimidazo[4,5-f]quinoline-mediated immunosuppression. Toxicology Letters 102-103 79-83
Lee YW, Hennig B, Fiala M, Kim KS and Toborek M (2001) Cocaine activates redox-regulated transcription factors and induces TNF-alpha expression in human brain endothelial cells. Brain Research 920 125-133
Lee YW, Hennig B, Yao J and Toborek M (2001) Methamphetamine induces AP-1 and NF-kB binding and transactivation in human brain endothelial cells. Journal of Neuroscience Research 66 583-591
Lee YW, Hirani AA, Kyprianou N and Toborek M (2005) Human immunodeficiency virus-1 Tat protein up-regulates interleukin-6 and interleukin-8 expression in human breast cancer cells. Inflammation Research 54 380-389
Lee YW, Malecki A and Toborek M (2003) Estrogen-mediated protection against methamphetamine-induced inflammatory pathways in human brain endothelial cells. Journal of Neurochemistry 85 2 36
Lee YW, Park HJ, Son KW, Hennig B, Robertson LW and Toborek M (2003) 2,2′,4,6,6′-pentachlorobiphenyl (PCB 104) induces apoptosis of human microvascular endothelial cells through the caspase-dependent activation of CREB. Toxicology and Applied Pharmacology 189 1-10
Lee YW, Son KW, Flora G, Hennig B, Nath A and Toborek M (2002) Methamphetamine activates DNA binding of specific redox-responsive transcription factors in mouse brain. Journal of Neuroscience Research 70 82-89
Lee YY, Kao CL, Tsai PH, Tsai TH, Chiou SH, Wu WF, Ku HH and WOng TT (2008) Caffeic acid phenethyl ester preferentially enhanced radiosensitizing and increased oxidative stress in medulloblastoma cell line. Childs Nervous System in press
Lee YY, Yang SF, Ho WH, Lee YH and Hung SL (2007) Eugenol modulates cyclooxygenase-2 expression through the activation of nuclear factor kB in human osteoblasts. Journal of Endodontics 33 1177-1182
Lee ZH and Kim HH (2003) Signal transduction by receptor activator of nuclear factor kB in osteoclasts. Biochemical and Biophysical Research Communications 305 211-214
Leeman JR and Gilmore TD (2008) Alternative splicing in the NF-kB signaling pathway. Gene 423 97-107
Leeman JR, Weniger MA, Barth TD and Gilmore TD (2008) Deletion analysis and alternative splicing define a transactivation inhibitory domain in human oncoprotein REL. Oncogene 27 677-6781
Leeper-Woodford SK and Detmer K (1999) Acute hypoxia increases alveolar macrophage tumor necrosis factor activity and alters NF-kB expression. American Journal of Physiology 276 L909-L916
Lefort S, Soucy-Faulkner A, Grandvaux N and Flamand L (2007) Binding of Kaposi’s sarcoma-associated herpesvirus K-bZIP to interferon responsive factor 3 elements modulates antiviral genes expression. Journal of Virology 81 10950-10960
Lefranc F, Brotchi J and Kiss R (2005) Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis. Journal of Clinical Oncology 23 2411-2422
Lefranc F, Mijatovic T, Mathieu V, Rorive S, Decaestecker C, Debeir O, Brotchi J, Van Ham P, Salmon I and Kiss R (2004) Characterization of gastrin-induced proangiogenic effects in vivo in orthotopic U373 experimental human glioblastomas and in vitro in human umbilical vein endothelial cells. Clinical Cancer Research 10 8250-8265
Lefstin JA and Yamamoto KR (1998) Allosteric effects of DNA on transcriptional regulators. Nature 392 885-888
Legarda D, Klein-Patel ME, Yim S, Yuk MH and Diamond G (2005) Suppression of NF-kB-mediated beta-defensin gene expression in the mammalian airway by the Bordetella type III secretion system. Cell Microbiol 7 489-497
Legarda-Addison D and Ting AT (2007) Negative regulation of TCR signaling by NF-kB2/p100. Journal of Immunology 178 7767-7778
Legembre P, Barnhart BC, and Peter ME (2004) The relevance of NF-kB for CD95 signaling in tumor cells. Cell Cycle 3 1235-1239
Legembre P, Barnhart BC, Zheng L, Vijayan S, Straus SE, Puck J, Dale JK, Lenardo M and Peter ME (2004) Induction of apoptosis and activation of NF-kB by CD95 require different signalling thresholds. EMBO Journal 5 1084-1089
Legembre P, Schickel R, Barnhart BC and Peter ME (2004) Identification of SNARK as a NF-kB regulated antiapoptotic kinase involved in CD95-induced motility and invasiveness. Journal of Biological Chemistry 279 46742-46747
Legendre F, Bogdanowicz P, Martin G, Domagala F, Leclercq S, Pujol JP and Ficheux H (2007) Rhein, a diacerhein-derived metabolite, modulates the expression of matrix degrading enzymes and the cell proliferation of articular chondrocytes by inhibiting ERK and JNK-AP-1 dependent pathways. Clinical and Experimental Rheumatology 25 546-555
Leger DY, Liagre B and Beneytout JL (2006) Role of MAPKs and NF-kB in diosgenin-induced megakaryocytic differentiation and subsequent apoptosis in HEL cells.International Journal of Oncology 28 201-207
Legler DF, Micheau O, Doucey MA, Tschopp J and Bron C (2003) Recruitment of TNF receptor 1 to lipid rafts is essential for TNFa-mediated NF-kB activation. Immunity 18 655-664
Legrand-Poels S, Bours V, Piret B, Pflaum M, Epe B, Rentier B and Piette J (1995) Transcription factor NF-kB is activated by photosensitization generative oxidative DNA damage. Journal of Biological Chemistry 270 6925-6934
Legrand-Poels S, Kustermans G, Bex F, Kremmer E, Kufer TA and Piette J (2007) Modulation of Nod2-dependent NF-kB signaling by the actin cytoskeleton. Journal of Cell Science in press
Legrand-Poels S, Schoonbroodt S, Matroule J-Y and Piette J (1998) NF-kB: an important transcription factor in photobiology. Journal of Photochemistry and Photobiology 45 1-8
Legssyer R, Josse C, Piette J, Ward RJ and Crichton RR (2003) Changes in function of iron-loaded alveolar macrophages after in vivo administration of desferrioxamine and/or chloroquine. Journal of Inorganic Biochemistry 94 36-42
Lehmann M, Jiang C, Ip YT and Thummel CS (2002) AP-1, but not NF-kB, is required for efficient steroid-triggered cell death in Drosophila. Cell Death and Differentiation 9 581-590
Lehmann T, Murphy C, Zahra DG and Handel ML (2002) Reduction of tumor necrosis factor induced nuclear factor-kB nuclear translocation and DNA binding by dexamethasone in human osteoarthritic synovial tissue explants. Journal of Rheumatology 29 787-795
Lehmann TG, Wheeler MD, Froh M, Schwabe RF, Bunzendahl H, Samulski RJ, Lemasters JJ, Brenner DA and Thurman RG (2003) Effects of three superoxide dismutase genes delivered with an adenovirus on graft function after transplantation of fatty livers in the rat. Transplantation 76 28-37
Lehming N, McGuire S, Brickman JM and Ptashne M (1995) Interactions of a Rel protein with its inhibitor. Proceedings of the National Academy of Sciences USA 92 10242-10246
Lehming N, Thanos D, Brickman JM, Ma J, Maniatis T and Ptashne M (1994) An HMG-like protein that can switch a transcriptional activator to a repressor. Nature 371 175-179
Lehnhardt A, Mengel M, Pape L, Ehrich JH, Offner G and Strehlau J (2006) Nodular B-cell aggregates associated with treatment refractory renal transplant rejection resolved by rituximab.
American Journal of Transplantation 6 847-851
Lehoux G, Le Gouill C, Stankova J and Rola-Pleszczynski M (2003) Upregulation of expression of the chemokine receptor CCR5 by hydrogen peroxide in human monocytes. Mediators of Inflammation 12 29-35
Lehoux S and Tedgui A (2003) All strain, no gain: stretch keeps proliferation at bay via the NF-kB response gene iex-1. Circulation Research 93 1139-1141
Lehrke M, Millington SC, Lefterova M, Cumaranatunge RG, Szapary P, Wilensky R, Rader DJ, Lazar MA and Reilly MP (2007) CXCL16 is a marker of inflammation, atherosclerosis, and acute coronary syndromes in humans. Journal of the American College of Cardiology 49 442-449
Lehrke M, Reilly MP, Millington SC, Iqbal N, Rader DJ and Lazar MA (2004) An inflammatory cascade leading to hyperresistinemia in humans. PLoS Medicine 1 e45
Lehtonen A, Veckman V, Nikula T, Lahesmaa R, Kinnunen L, Matikainen S and Julkunen I (2005) Differential expression of IFN regulatory factor 4 gene in human monocyte-derived dendritic cells and macrophages. Journal of Immunology 175 6570-6579
Lei FF, Zhao JX, Wang XX, Yao BT and Ding K (2007) Study on depressant effects of THPS on S180 tumor-bearing-mice and its mechanisms [Article in Chinese]. Zhong Ya Cai 30 1548-1551
Lei HY and Zhao XL (2007) Clinical significance of NF-kB continual activity and expression of WT1 and MDR1 in acute nonlymphocytic leukemia [Article in Chinese]. Zhongguo Shi Yan Xue Ye Xue Za Zhi 15 253-257
Leiba M, Cahalon L, SHimoni A, LIder O, Zanin-Zhorov A, Hecht I, Sela U, Vlodavsky I and Nagler A (2006) Halofuginone inhibits NF-kB and p38 MAPK in activated T cells. Journal of Leukocyte Biology in press
Leidner J, Palkowitsch L, Marienfeld U, Fischer D and Marienfeld R (2008) Identification of lysine residues critical for the transcriptional activity and poly-ubiquitination of the NF-kB family member RelB. Biochemical Journal in press
Leigh R, Oyelusi W, Wiehler S, Koetzler R, Zaheer RS, Newton R and Proud D (2008) Human rhinovirus infection enhances airway epithelial cell production of growth factors involved in airway remodeling. Journal of Allergy and Clinical Immunology in press
Leiro J, Arranz JA, Fraiz N, Sanmartin ML, Quezada E and Orallo F (2005) Effect of cis-resveratrol on genes involved in nuclear factor kB signaling. International Immunopharmacology 5 393-406
Leiro J, Arranz JA, Yanez M, Ubeira FM, Sanmartin ML and Orallo F (2004) Expression profiles of genes involved in the mouse nuclear factor-kB signal transduction pathway are modulated by mangiferin. International Immunopharmacology 4 763-778
Leiro J, Garcia D, Arranz JA, Delgado R and Sanmartin ML and Orallo F (2004) An Anacardiaceae preparation reduces the expression of inflammation-related genes in murine macrophages. International Immunopharmacology 4 991-1003
Leis H, Page A, Ramirez A, Bravo A, Segrelles C, Paramio J, Barettino D, Jorcano JL and Perez P (2003) Glucocorticoid Receptor counteracts tumorigenic activity of Akt in skin through interference with the phosphatidylinositol 3-kinase (PI3K) signaling pathway. Molecular Endocrinology 18 303-311
Leis H, Sanchis A and Perez P (2006) Deletion of the N-terminus of IKKg induces apoptosis in keratinocytes and impairs the AKT/PTEN signaling pathway.Experimental Cell Research in press
Leitges M, Sanz L, Martin P, Duran A, Braun U, Garcia JF, Camacho F, Diaz-Meco MT, Rennert PD and Moscat J (2001) Targeted disruption of the zetaPKC gene results in the impairment of the NF-kB pathway. Molecular Cell 8 771-780
Leitinger N, Huber J, Rizza C, Mechtcheriakova D, Bochkov V, Koshelnick Y, Berliner JA and Binder BR (2001) The isoprostane 8-iso-PGF(2alpha) stimulates endothelial cells to bind monocytes: differences from thromboxane-mediated endothelial activation. FASEB Journal 15 1254-1256
Leiva M, Ruiz-Breavo A, Moreno E and Jimenez-Valera M (2008) Telithromycin inhibits the production of proinflammatory mediators and the activation of NF-kB in in vitro-stimulated murine cells. FEMS Immunology and Medical Microbiology in press
Leleu X, Eeckhoute J, Jia X, Roccaro AM, Moreau AS, Farag M, Sacco A, Ngo HT, Runnels J, Melham MR, Burwick N, Azab A, Azab F, Hunter Z, Hatjiharissi E, Carrasco DR, Treon SP, Witzip TE, Hideshima T, Brown M, Anderson KC and Ghobrial IM (2008) Targeting NF-kB in Waldenstrom macroglobulinemia. Blood in press
Lelkes PI, Hahn KL, Sukovich DA, Karmiol S and Schmidt DH (1998) On the possible role of reactive oxygen species in angiogenesis. Adv Exp Med Biol 454 295-310
Lemarie CA, Tharaux PL, Esposito B, Tedgui A and Lehoux S (2006) Transforming growth factor-a mediates nuclear factor kB activation in strained arteries.Circulation Research in press
Lemaitre B, Nicolas E, Michaut L, Reichart J-M and Hoffmann JA (1996) The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86 973-983
Lemaitre B, Reichhart J-M and Hoffman JA (1997) Drosophila host defense: Differential induction of antimicrobial peptide genes after infection by various classes of microorganisms. Proceedings of the National Academy of Sciences USA 94 14614-14619
Lemarie A, Lagadic-Gossmann D, Morzadec C, Allain N, Fardel O and Vernhet L (2004) Cadmium induces caspase-independent apoptosis in liver Hep3B cells: role for calcium in signaling oxidative stress-related impairment of mitochondria and relocation of endonuclease G and apoptosis-inducing factor. Free Radic Biol Med 36 1517-1531
LeMarie A, Morzadec C, Merino D, Micheau O, Fardel O and Vernhet L (2005) Arsenic trioxide induces apoptosis of human monocytes during macrophagic differentiation through NF-kB-related survival pathway downregulation. J Pharmacol Exp Ther in press
Lemarie CA, Esposito B, Tedgui A and Lehoux S (2003) Pressure-induced vascular activation of Nuclear Factor-kB. Role in cell survival. Circulation Research 93 207-212
Lemay S, Lebedeva TV and Singh AK (1999) Inhibition of cytokine gene expression by sodium salicylate in a macrophage cell line through an NF-kB-independent mechanism. Clin Diagn Lab Immunol 6 567-572
Lemieux AM, Pare ME, Audet B, Legault E, Lefort S, Boucher N, Landry S, van Opijnen T, Berkhout B, Naghavi MH, Tremblay MJ and Barbeau B (2004) T cell activation leads to poor activation of HIV-1 clade E LTR and weak association of NF-kB and NFAT to its enhancer region. Journal of Biological Chemistry 279 52949-52960
Lemaout C, Gonzalez H, Aboab J and Annane D (2006) Pathophysiology of septic shock [Article in French]. Presse Med 35 521-527
Lemmers B, Salmena L, Bidere N, Su H, Matysiak-Zablocki E, Murakami K, Ohashi PS, Jurisicova A, Lenardo M, Hakem R and Hakem A (2007) Essenital role fo caspase-8 in Toll-like receptors and NFkB signaling. Journal of Biological Chemistry 282 7416-7423
Lemster BH, Michel JJ, Montag DT, Paat JJ, Studenski SA, Newman AB and Vallejo AN (2008) Induction of CD56 and TCR-independent activation of T cells with aging. Journal of Immunology 180 1979-1990
Lenardo M and Baltimore D (1989) NF-kB: a pleiotropic mediator of inducible and tissue-specific gene control. Cell 58 227-229
Lenardo M and Siebenlist U (1994) Bcl-3-mediated nuclear regulation of the NF-kB trans-activating factor. Immunology Today 15 145-147
Lenardo MJ, Fan CM, Maniatis T and Baltimore D (1989) The involvement of NF-kB in beta-interferon gene regulation reveals its role as widely inducible mediator of signal transduction. Cell 57 287-294
Lenardo MJ, Kuang A, Gifford A and Baltimore D 91989) Purified bovine NF-kB recognizes regulatory sequences in multiple genes expressed during activation of T- and B-lymphocytes. Hamatol Bluttransfus 32 411-415
Lenardo MJ, Kuang A, Gifford A and Baltimore D (1988) NF-kB protein purification from bovine spleen: nucleotide stimulation and binding site specificity. Proceedings of the National Academy of Sciences USA 85 8825-8829
Lenardo N, Pierce JW and Baltimore D (1988) Protein-binding sites in Ig gene enhancers determine transcriptional activity and inducibility. Science 236 1573-1577
Lendemans S, Rani M, Selbach C, Kreuzfelder E, Schade FU and Flohe S (2006) GM-CSF priming of human monocytes is dependent on ERK1/2 activation. Journal ofEndotoxin Research 12 10-20
Lenert P, Goeken AJ and Ashman RF (2006) Extended sequence preferences for oligodeoxyribonucleotide activity. Immunology 117 474-481
Lenert P, Stunz L, YI AK, Krieg AM and Ashman RFCpG stimulation of primary mouse B cells is blocked by inhibitory oligodeoxyribonucleotides at a site proximal to NF-kB activation. Antisense Nucleic Acid Drug Development 11 247-256
Lenhard JM and Gottschalk WK (2002) Preclinical developments in type 2 diabetes. Advances in Drug Delivery Reviews 54 1199
Lentsch AB (2005) Activation and function of hepatocyte NF-kB in postischemic liver injury. Hepatology 42 216-218
Lentsch AB and Ward PA (1999) Activation and regulation of NFkB during acute inflammation. Clin Chem Lab Med 37 205-208
Lentsch AB, Crouch LD, Jordan JA, Czermak BJ, Yun EC, Guo R, Sarma V, Diehl KM and Ward PA (1999) Regulatory effects of interleukin-11 during acute lung inflammatory injury. Journal of Leukocyte Biology 66 151-157
Lentsch AB, Czermak BJ, Bless NM, Van Rooijen N and Ward PA (1999) Essential role of alveolar macrophages in intrapulmonary activation of NF-kB. American Journal of Respiratory Cell and Molecular Biology 20 692-698
Lentsch AB, Czermak BJ, Jordan JA and Ward PA (1999) Regulation of acute lung inflammatory injury by endogenous IL-13. Journal of Immunology 162 1071-1076
Lentsch AB, Jordan JA, Czermak BJ, Diehl KM, Younkin EM, Sarma V and Ward PA (1999) Inhibition of NF-kB activation and augmentation of IkBb by secretory leukocyte protease inhibitor during lung inflammation. American Journal of Pathology 154 239-247
Lentsch AB, Kato A, Davis B, Wang W, Chao C and Edwards MJ (2001) STAT4 and STAT6 regulate systemic inflammation and protect against lethal endotoxemia. Journal of Clinical Investigation 108 1475-1482
Lentsch AB, Pathrose P, Kader S, Kuboki S, Collins MH and Waltz SE (2007) The Ron receptor tyrosine kinase regualtes acute lung injury and suppresses nuclear factor kB activation. Shock 27 274-280
Lentsch AB, Shanley TP, Sarma V and Ward PA (1997) In vivo suppression of nuclear factor kB and preservation of IkBa by interleukin-10 and interleukin-3. Journal of Clinical Investigation 100 2443-2448
Lentsch AB, Yoshidome H, Warner RL, Ward PA and Edwards MJ (1999) Secretory leukocyte protease inhibitor in mice regulates local and remote organ inflammatory injury induced by hepatic ischemia/reperfusion. Gastroenterology 117 953-961
Lentschat A, Karahashi H, Michelsen KS, Thomas LS, Zhang W, Vogel SN and Arditi M (2005) Mastoparan, a G protein agonist peptide, differentially modulates TLR4- and TLR2-mediated signaling in human endothelial cells and murine macrophages. Journal of Immunology 17 4252-4261
Lenz G, Davis RE, Ngo VN, Lam L, George TC, Wright GW, Dave SS, Zhao H, Xu W, Rosenwald A, Ott G, Muller-Hermelink HK, Gascoyne RD, Connors JM, Rimsza LM, Campo E, Jaffe ES, Delabie J, Smeland EB, Fisher RJ, Chan WC and Staudt LM (2008) Oncogenic CARD11 mutations in human diffuse large B cell lymphoma. Science in press
Lenz HJ (2003) Clinical update: proteasome inhibitors in solid tumors. Cancer Treatment Reviews 29 Suppl 1 41-48
Leo E, Deveraux Q, Buchholtz C, Welsh K, Matsuzawa S, Stennicke H, Salvesen GS and Reed JC (2000) TRAF1 is a substrate of caspases activated during tumor necrosis factor receptor-a induced apoptosis. Journal of Biological Chemistry 276 8087-8093
Leo E, Welsh K, Matsuzawa S, Zapata JM, Kitada S, Mitchell RS, Ely KR and Reed JC (1999) Differential requirements for tumor necrosis factor receptor-associated factor family proteins in CD40-mediated induction of NF-kB and Jun N-terminal kinase activation. Journal of Biological Chemistry 274 22414-22422
Leonard J, Parrott C, Buckler-White AJ et al (1989) The NF-kB binding sites in the human immunodeficiency virus type 1 long terminal repeat are not required for virus infectivity. Journal of Virology 63 4919-4924
Leonard SS, Harris GK and Shi X (2004) Metal-induced oxidative stress and signal transduction. Free Radic Biol Med 37 1921-1942
Leonard SS, Roberts JR, Antonini JM, Castranova V and Shi X (2004) PbCrO4 mediates cellular responses via reactive oxygen species. Molecular and Cellular Biochemistry 255 171-179
Leonard SS, Wang S, Shi X, Jordan BS, Castranova V and Dubick MA (2000) Wood smoke particles generate free radicals and cause lipid peroxidation, DNA damage, NFkB activation and TNF-a release in macrophages. Toxicology 150 147-157
Leonard SS, Xia C, Jiang BH, Stinefelt B, Klandorf H, Harris GK and Shi X (2003) Resveratrol scavenges reactive oxygen species and effects radical-induced cellular responses. Biochemical and Biophysical Research Communications 309 1017-1026
Leonardi A, Ellinger-Ziegelbauer H, Franzoso G, Brown K and Siebenlist U (2000) Physical and functional interaction of filamin (actin-binding protein-280) and tumor necrosis factor receptor-associated factor 2. Journal of Biological Chemistry 275 271-278
Leonardi A, Vito P, Mauro C, Pacifico F, Ulianich L, Consiglio E, Formisano S and Di Jeso B (2002) Endoplasmic reticulum stress causes thyroglobulin retention in this organelle and triggers activation of nuclear factor-kB via tumor necrosis factor receptor-associated factor 2. Endocrinology 143 2169-2177
Leonarduzzi G, Gamba P, Sottero B, Kadl A, Robbesyn F, Calogero RA, Biasi F, Chiarpotto E, Leitinger N, Sevanian A and Poli G (2005) Oxysterol-induced up-regulation of MCP-1 expression and synthesis in macrophage cells. Free Radical Biology and Medicine 39 1152-1161
Leonarduzzi G, Robbesyn F and Poli G (2004) Signaling kinases modulated by 4-hydroxynonenal. Free Radical Biology & Medicine 37 1694-1702
Leone MJ, Marpegan L, Bekinschtein TA, Costas MA and Golombek DA (2006) Suprachiasmatic astrocytes as an interface for immune-circadian signalling.Journal of Neuroscience Research 84 1521-1527
LePage C, Popescu O, Genin P, Lian J, Paquin A, Galipeau J, Hiscott J (2001) Disruption of NF-kB signaling and chemokine gene activation by retroviral mediated espression of IKKy/NEMO mutants. Virology 286 422-433
Leppert BJ, Mansfield JM and Paulnock DM (20070 The soluble variant surface glycoprotein of African trypanosomes is recognized by a macrophage scavenger receptor and induces IkBa degradation independently of TRAF6-mediated TLR signaling. Journal of Immunology 179 548-556
Lerma E, Peiro G, Ramon T, Fernandez S,Martinez D, Pons C, Munoz F, Sabate JM, Alonso C, Ojeda B, Prat J and Barnadas A (2007) Immunohistochemical heterogeneity of breast carcinomas negative for estrogen receptors, progesterone receptors and Her2/neu (basal-like breast carcinomas). Modern Pathology in press
Lernbecher T, Müller U and Wirth T (1993) Distinct NF-kB/Rel transcription factors are responsible for tissue-specific and inducible gene activation. Nature 365 767-770
Lerner CG, Horton MR, Schwartz RH and Powell JD (2000) Distinct requirements for C-C chemokine and IL-2 production by naive, previously activated, and anergic T cells. Journal of Immunology 164 3996-4002
Lerner-Marmarosh N, Miralem T, Gibbs PE and Maines MD (2007) Regulation of TNF-a-activated PKC-{zeta} signaling by the human biliverdin reductase: Identification of activating and inhibitory domains of the reductase. FASEB Journal in press
Lerner-Marmarosh N, Yoshizumi M, Che W, Surapisitchat J, Kawakatsu H, Akaike M, Ding B, Huang Q, Yan C, Berk BC and Abe JI (2003) Inhibition of tumor necrosis factor-a-Induced SHP-2 phosphatase activity by shear stress. A mechanism to reduce endothelial inflammation. Arteriosclerosis, Thrombosis and Vascular Biology 23 1775-1781
Lerner-Natoli M, Montpied P, Rousset MC, Bockaert J and Rondouin G (2000) Sequential expression of surface antigens and transcription factor NFkB by hippocampal cells in excitotoxicity and experimental epilepsy. Epilepsy Research41 141-154
Lesage D, Metelev V, Borisova O, Dolinnaya N, Oretskaya T, Baran-Marszak F, Taillandier E, Raphael M and Fagard R (2003) Specific covalent binding of a NF-kB decoy hairpin oligonucleotide targeted to the p50 subunit and induction of apoptosis. FEBS Letters 547 115-118
Lesiak K, Sztiller-Sikorska M and Czyz M (2007) Transcription factors in the development and progression of melanoma. Postepy Hig Med Dosw 61 576-595
Leskinen MJ, Heikkila HM, Speer MY, Hakala JK, Laine M, Kovanen PT and Lindstedt KA (2006) Mast cell chymase induces smooth muscle cell apoptosis by disrupting NF-kB-mediated survival signaling. Experimental Cell Research in press
Lesley R, Xu Y, Kalled SL, Hess DM, Schwab SR, Shu HB and Cyster JG (2004) Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF. Immunity 20 441-453
Leslie M (2004) Ironing out cell death. Sci Aging Knowledge Environ (46) nf102
Lesner A, Li Y, Nitkiewicz J, Li G, Kartvelishvili A, Kartvelishvili M and Simm M (2005) A soluble factor secreted by an HIV-1-resistant cell line blocks transcription through inactivating the DNA-binding capacity of the NF-kB p65/p50 dimer. Journal of Immunology 175 2548-2554
Lessard L, Begin LR, Gleave ME, Mes-Masson AM, and Saad F (2005) Nuclear localisation of nuclear factor-kB transcription factors in prostate cancer: an immunohistochemical study. British Journal of Cancer 93 1019-1023
Lessard L, Karakiewicz PI, Bellon-Gagnon P, Alam-Fahmy M, Ismail HA, Mes-Masson AM and Saad F (2006) Nuclear localization of nuclear factor-kB p65 in primary prostate tumors is highly predictive of pelvic lymph node metastases. ClinicalCancer Research 12 5741-5745
Lessard L, Mes-Masson AM and Saad F (2006) NFkB; a new marker capable of predicting prostate cancer oucome. Bulletin of Cancer 93 891-899
Lessard L, Saad F, Le Page C, Diallo JS, Peant B, Delvoye N and mes-Masson AM (2007) NF-kB2 processing and p52 nuclear accumulation after androgenic stimulation of LNCaP prostate cancer cells. Cellular Signaling in press
Letiembre M, Echchannaoui H, Ferracin F, Rivest S and Landmann R (2005) Toll-like receptor-2 deficiency is associated with enhanced brain TNF gene expression during pneumococcal meningitis. Journal of Neuroimmunology 168 21-33
Letoha T, Feher LZ, Pecze L, Somlai C, Varga I, Kaxzaki J, Toth G, Vizler C, Tiszlavica L and Takacs T (2007) Therapeutic proteasome inhibition in experimental acute pancreatitis.
World Journal of Gastroenterology 13 4452-4457
Letoha T, Kusz E, Papai G, Szabolcs A, Kaszaki J, Varga I, Takacs T, Penke B and Duda E (2006) In vitro and in vivo NF-kB inhibitory effects of the cell-penetrating penetratin peptide. Molecular Pharmacology in press
Letoha T, Somlai C, Takacs T, Szabolcs A, Jarmay K, Rakonczay-Jr Z, Hegyi P, Varga I, Kaszaki J, Krizbai I, Boros I, Duda E, Kusz E and Penke B (2005) A nuclear import inhibitory peptide ameliorates the severity of cholecystokinin-induced acute pancreatitis. World Journal of Gastroenterology 11 990-999
Letoha T, Somlai C, Takacs T, Szabolcs A, Rakonczay Jr Z, Jarmay K, Slalontai T, Varga I, Kaszaki J, Boros I, Duda E, Hackler L, Kurucz I and Penke B The proteasome inhibitor MG132 protects against acute pancreatitis. Free Radic Biol Med 39 1142-1151
Leu TH and Maa MC (2003) The molecular mechanisms for the antitumorigenic effect of curcumin. Curr Med Chem Anti-Cancer Agents 2 357-370
Leuenroth SJ and Crews CM (2008) Triptolide-induced transcriptional arrest is associated with changes in nuclear substructure. Cancer Research 68 5257-5266
Leulier F, Lhocine N, Lemaitre B and Meier P (2006) The Drosophila IAP DIAP2 functions in innate immunity and is essential to resist gram-negative bacterial infection. Molecular and Cellular Biology in press
Leulier F, Marchal C, Miletich I, Limbourg-Bouchon B, Benarous R and Lemaitre B (2003) Directed expression of the HIV-1 accessory protein Vpu in Drosophila fat-body cells inhibits Toll-dependent immune responses. EMBO Reports 4 976-981
Leulier F, Vidal S, Saigo K, Ueda R and Lemaitre B (2002) Inducible expression of double-stranded RNA reveals a role for dFADD in the regulation of the antibacterial response in Drosophila adults. Current Biology 12 996-1000
Leung CH, Grill SP, Lam W, Han QB, Sun HD and Cheng YC (2005) Novel mechanism of inhibition of NF-kB DNA-binding activity by diterpenoids isolated from Isodon rubescens. Molecular Pharmacology 68 286-297
Leung CH, Grill SP, Lam W, Gao W, Sun HD and Cheng YC (2006) Eriocalyxin B inhibits NF-kB activation by interfereing with the binding of both p65 and p50 to the response element in a non-competitive manner. Molecular Pharmacology in press
Leung CY, Liu L, Wong RN, Zeng YY, Li M and Zhou H (2005) Saikosaponin-d inhibits T cell activation through the modulation of PKCtheta, JNK, and NF-kB transcription factor. Biochemical and Biophysical Research Communications in press
Leung JC, Tang SC, Chan LY, Chan WL and Lai KN (2007) Synthesis of TNF-a by mesangial cells cultured with polymeric anionic IgA role of MAPK and NF-kB.Nephrology, Dialysis, Transplantation in press
Leung JY, Chapman JA, Harris JA, Hale D, Chung RS, West AK and Chuah MI (2008) Olfactory ensheathing cells are attracted to, and can endocytose, bacteria. Cell and Molecular Life Sciences in press
Leung K and Nabel G (1988) HTLV-1 transactivator induces interleukin-2 receptor through an NF-kB-like factor. Nature 333 776-778
Leung TH, Hoffmann A and Baltimore D (2004) One nucleotide in a kB site can determine cofactor specificity for NF-kB dimers. Cell 118 453-464
Leung TM, Tipoe Gl, Liong EC, Lau TY, Fung ML and Nanji AA (2008) Endothelial nitric oxide synthase is a critical factor in experimental liver fibrosis. International Journal of Experimental Pathology in press
Leurs R, Church MK and Taglialatela M (2002) H1-antihistamines: inverse agonism, anti-inflammatory actions and cardiac effects. Clin Exp Allergy 32 489-498
Lev DC, Ruiz M, Mills L, McGary EC, Price JE and Bar-Eli M (2003) Dacarbazine causes transcriptional up-regulation of interleukin 8 and vascular endothelial growth factor in melanoma cells: a possible escape mechanism from chemotherapy. Molecular Cancer Therapy 2 753-763
Léveillard T and Verma IM (1993) Diverse molecular mechanisms of inhibition of NF-kB/DNA binding complexes by IkB proteins. Gene Expression 3 135-150
Levenson JM, Choi S, Lee SY, Cao YA, Ahn HJ, Worley KC, Pizzi M, Liou HC and Sweatt JD (2004) A bioinformatics analysis of memory consolidation reveals involvement of the transcription factor c-Rel. Journal of Neuroscience 24 3933-3943
Leverkus M, Diessenbacher P and Geserick P (2008) FLIP ing the coin? Death receptor-mediated signals during skin tumorigenesis. Experimental Dermatology 17 614-622
Leverkus M, Sprick MR, Wachter T, Denk A, Brocker EB, Walczak H and Neumann M (2003) TRAIL-induced apoptosis and gene induction in HaCaT keratinocytes: differential contribution of TRAIL receptors 1 and 2. Journal of Investigative Dermatology 121 149-155
Leverkus M, Sprick MR, Wachter T, Mengling T, Baumann B, Serfling E, Brocker EB, Goebeler M, Neumann M and Walczak H (2003) Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation. Molecular and Cellular Biology 23 777-790
Levi E, Pfeifer WM and Kadin ME (2001) CD30-activation-mediated growth inhibition of anaplastic large-cell lymphoma cell lines: apoptosis or cell-cycle arrest? Blood 98 1630-1632
Levidou G, Korkolopoulou P, Nikiteas N, Tzanakis N, Thymara I, Saetta AA Tsigris C, Rallis G, Vlasis K and Patsouris E (2007) Expression of nuclear factor kB in human gastric carcinoma: relationship with IkBa and prognostic significance.Virchows Archiv 450 519-527
Levidou G, Saetta AA, Korkolopoulou P, Papanastasiou P, Gioti K, Pavlopoulos P, Diamantopoulou K, Thomas-Tsagli E, Xiromeritis K and Patsouris E (2008) Clinical significance of nuclear factor (NF)-kB levels in urothelial carcinoma of the urinary bladder. Virchows Archiv in press
Levine A, Karban A, Eliakim R, Shaoul R, Reif S, Pacht A, Wardi J, Yakir B and Silver EL (2005) A polymorphism in the TNF-a promoter gene is associated with pediatric onset and colonic location of Crohn’s Disease. American Journal of Gastroenterology 100 407-413
Levine A, Tenhaken R, Dixon R and Lamb C (1994) H2O2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response. Cell 79 583-593
Levine GK, Deutschman CS, Helfaer MA and Margulies SS (2006) Sepsis-induced lung injury in rats increases alveolar epithelial vulnerability to stretch. CriticalCare Medicine in press
Levine RA, McDormack JE, Buckler A and Sonenshein GE (1986) Complex regulation of c-myc gene expression in a murine B cell lymphoma. Current Topics in Microbiology and Immunology 132 305-312
Levites Y, Youdim MB, Maor G and Mandel S (2002) Attenuation of 6-hydroxydopamine (6-OHDA)-induced nuclear factor-kB (NF-kB) activation and cell death by tea extracts in neuronal cultures. Biochemical Pharmacology 63 21-29
Levitsky VG, Ignatieva EV, Ananko EA, Turnaev II, Merkulova TK, Kolchanov NA and Hodgman TC (2007) Effective transcription factor binding site prediction using a combination of optimization, a genetic algorithm and discriminant analysis to capture distant interactions. BMC Bioinformatics in press
Levkau B, Garton KJ, Ferri N, Kloke K, Nofer JR, Baba HA, Raines EW and Breithardt G (2001) xIAP induces cell-cycle arrest and activates nuclear factor-kB : new survival pathways disabled by caspase-mediated cleavage during apoptosis of human endothelial cells. Circulation Research 88 282-290
Levkau B, Scatena M, Giachelli CM, Ross R and Raines EW (1999) Apoptosis overrides survival signals through a caspase-mediated dominant-negative NF-kB loop. Nature Cell Biology 1 227-233
Levrand S, Pesse B, Feihl F, Waeber B, Pacher P, Rolli J, Schaller MD and Liaudet L (2005) Peroxynitrite is a potent inhibitor of NF-kB activation triggered by inflammatory stimuli in cardiac and endothelial cell lines. Journal of Biological Chemistry 280 34878-34887
Levy DE, Marie I I and Prakash A (2002) Ringing the interferon alarm: differential regulation of gene expression at the interface between innate and adaptive immunity. Current Opinion in Immunology 15 52-58
Levy O, Suter EE, Miller RL and Wessels MR (2006) Unique efficacy of Toll-like receptor 8 agonists in activating human neonatal antigen-presenting cells. Blood108 1284-1290
Levy P, Robin H, Bertrand F, Kornprobst M and Capeau J (2003) Butyrate-treated colonic Caco-2 cells exhibit defective integrin-mediated signaling together with increased apoptosis and differentiation. Journal of Cell Physiology 197 336-347
Levy RM, MOllen KP, Prince JM, Kaczorowski DJ, Vallabhaneni R, Liu S, Tracey KJ, Lotze MT, Hackam DJ, Fink MP, Vodovotz Y and Billiar TR (2007) Systemic inflammation and remote organ injury following trauma require HMGB1. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology in press
Levy RM, Prince JM, Yang R, Mollen KP, Liao H, Watson GA, Fink MP, Vodovotz Y and Billiar TR (2006) Systemic inflammation and remote organ damage following bilateral femur fracture requires toll-like receptor 4. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 291 R970-R976
Lewin B (1990) Oncogenic conversion by regulatory changes in transcription factors. Cell 64 303-312
Lewis AJ and Manning AM (1999) New targets for anti-inflammatory drugs. Current Opinions in Chemistry and Biology 3 489-494
Lewis CC, Yang JY, Huang X, Banerjee SK, Blackbrun MR, Baluk P, McDonald DM, Blackwell TS, Nagabhushanam V, Peters W, Voehringer D and Erle DJ (2007) Disease-specific gene expression profiling in multiple models of lung disease. American Journal of Respiratory Critical Care Medicine in press
Lewis DA, Hengeltraub SF, Gao FC, Leivant MA and Spandau DF (2006) Aberrant NF-kB activity in HaCaT cells alters their response to UVB signaling. Journal ofInvestigative Dermatology 126 1885-1892
Lewis DA and Spandau DF (2007) UVB activation of NF-kB in normal human keratinocytes occurs via a unique mechanism. Archives of Dermatological Research299 93-101
Lewis DA and Spandau DF (2007) UVB-induced activation of NF-kB is regulated by the IGF-1R and dependent on p38 MAPK. Journal of Investigative Dermatology in press
Lewis H, Kaszubska W, DeLemarter JF and Whelan J (1994) Cooperativity between two NF-kB complexes, mediated by high-mobility-group protein I(Y), is essential for cytokine-induced expression of the E-selectin promoter. Molecular and Cellular Biology 14 5701-5709
Lewis J, Burstein E, Birkey Reffey S, Bratton SB, Roberts AB and Duckett CS (2004) Uncoupling of the signaling and caspase-inhibitory properties of XIAP. Journal of Biological Chemsitry 279 9023-9029
Lewis J, Devin A, Miller A, Lin Y, Rodriguez Y, Neckers L and Liu ZG (2000) Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kB activation. Journal of Biological Chemistry 275 10519-10526
Lewis JB, Randol TM, Lockwood PE and Wataha JC (2003) Effect of subtoxic concentrations of metal ions on NFkB activation in THP-1 human monocytes. J Biomed Mater Res 64A 217-224
Lewis K, Caldwell J, PHan V, Prescott D, Nazli A< Wang A, Soderholm JD, Perdue MH, Sherman PM and McKay DM (2008) Decreased epithelial barrier function evoked by exposure to metabolic stress and non-pathogenic E. coli is enhanced by TNFa. American Journal of Physiology: Gastrointestinal and Liver Physiology in press
Lewis MJ, Sheehy N, Salemi M, VanDamme A-M and Hall WW (2002) Comparison of CREB- and NF-kB-mediated transactivation by Human T lymphotropic virus type II (HTLV-II) and Type 1 (HTLV-I) Tax proteins. Virology 295 182-189
Lewis R, McClure J, Rup B, Niesel DW, Garry RF, Hoelzer JD, Nazerian K and Bose Jr HR (1981) Avian reticuloendotheliosis virus: identification of the hematopoietic target cell for transformation. Cell 25 421-431
Lewis RS (2003) Calcium oscillations in T-cells: mechanisms and consequences for gene expression. Biochem Soc Trans 31 925-929
Leyva-Baca I, Schenkel F, Martin J and Karrow NA (2008) Polymorphisms in the 5′ upstream region of the CXCR1 chemokine receptor gene, and their association with somatic cell score in Holstein cattle in Canada. Journal of Dairy Science 91 407-417
Lezoualch F, Engert S, Berning B and Behl C (2000) Corticotropin-releasing hormone-mediated neuroprotection against oxidative stress is associated with the increased release of non-amyloidogenic amyloid beta precursor protein and with the suppression of nuclear factor-kB. Molecular Endocrinology 14 147-159
Lgssiar A, Hassan M, Schott-Ohly P, Friesen N, Nicoletti F, Trepicchio WL and Gleichmann H (2004) Interleukin-11 inhibits NF-kB and AP-1 activation in islets and prevents diabetes induced with streptozotocin in mice. Exp Biol Med (Maywood) 229 425-436
L’Heureux MC and Brubaker PL (2003) Glucagon-like Peptide-2 and common therapeutics in a murine model of ulcerative colitis. Journal of Pharmacology and Experimental Therapeutics 306 347-354
Li A, He M, Wang H, Qiao B, Chen P, Gu H, Zhang M and He S (2007) All-trans retinoic acid negatively regulates cytotoxic activities of natural killer cell line 92. Biochemical and Biophysical Research Communications 352 42-47
Li B, Zhang R, Li J, Zhang L, Deing G, Luo P, He S, Dong Y, Jiang W, Lu Y, Cao H, ZHeng J and ZHou H (2008) Antimalarial artesunate protects sepsis model mice against heat-killed Escherichia coli challenge by decreasing TLR4, TLR9 mRNA expressions and transcription factor NF-kB activation. International Immunopharmacology 8 379-389
Li BG, Feng DY, Cheng RX, He QQ, Hu ZL, Zheng H and Wen JF (2005) The effects of hepatitis C virus core protein on biological behaviors of human hepatocytes [Article in Chinese]. Zhonghua Yi Xue Za Zhi 85 1243-1248
Li BA, Heng Y, Hou J, Gao R, Li J, Zheng Y, Su Q and Fu TQ (2002) Sero-and molecular epidemilogy of the gene of different ORF of transfusion transmitted virus (TTV) in different population of China [Article in Chinese]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 16 79-81
Li C, Bardhan S, Pace EA, Liang M-C, Gilmore TD and Porco JA Jr (2002) Angiogenesis inhibitor epoxyquinol A: total synthesis and inhibition of transcription factor NF-kB. Organic Letters 4 3267-3270
Li C, Browder W and Kao RL (1999) Early activation of transcription factor NF-kB during ischemia in perfused rat heart. American Journal of Physiology 276 H543-H552
Li C, Ha T, Kelley J, Gao X, Qiu Y, Kao RL, Browder W and Williams DL (2004) Modulating Toll-like receptor mediated signaling by (1–>3)-beta-d-glucan rapidly induces cardioprotection. Cardiovascular Research 61 538-547
Li C, Ha T, Liu L, Browder W and Kao RL (2000) Adenosine prevents activation of transcription factor NF-kB and enhances activator protein-1 binding activity in ischemic rat heart. Surgery 127 161-169
Li C, Kao RL, Ha T, Kelley J, Browder IW and Williams DL (2001) Early activation of IKKbeta during in vivo myocardial ischemia. Am J Physiol Heart Circ Physiol 280 H1264-H1271
Li C, Kelley J and Ha T (2005) Activation of nuclear factor-kB. Methods in Molecular Biology 315 141-150
Li C, Ni CZ, Havert ML, Cabezas E, He J, Kaiser D, Reed JC, Satterthwait AC, Cheng G and Ely KR (2002) Downstream regulator TANK binds to the CD40 recognition site on TRAF3. Structure (Cambridge) 10 403-411
Li C, Norris PS, Ni CZ, Havert ML, Chiong EM, Tran BR, Cabezas E, Reed JC, Satterthwait AC, Ware CF and Ely KR (2003) Structurally distinct recognition motifs in lymphotoxin-beta receptor and CD40 for TRAF-mediated signaling. Journal of Biological Chemistry 278 50523-50529
Li C, Pace EA, Liang M-C, Lobkovsky E, Gilmore TD and Porco Jr JA (2001) Total synthesis of the NF-kB inhibitor (-)-cycloepoxydon: utilization of tartrate-mediated nucleophilic exclusion. Journal of the American Chemical Society 123 11308-11309
Li C, Zhang Y, Liu Z, Yu M and Yu W (2008) Helicobacter pylori VacA up-regulates secretion of macrophages by transfection of VacA eukaryotic expression vector [Article in Chinese]. Wei Sheng Wu Xue Bao 48 349-354
Li CC, Chou CK, Wang MH and Tsai TF (2006) Overexpression of ABIN-2, a negative regulator of NF-kB, delays liver regeneration in the ABIN-2 transgenic mice.Biochemical and Biophysical Research Communications 342 300-309
Li CC, Xie ZX, Zhang YD, Chen JH and Yang Z (2003) Total synthesis of wedelolactone. Journal of Organic Chemistry 68 8500-8504
Li C-C H, Dai R-M and Longo DL (1995) Inactivation of NF-kB inhibitor IkBa: ubiquitin-dependent proteolysis and its degradation product. Biochemical and Biophysical Research Communications 215 292-301
Li C-C H, Dai R-M, Chen E and Longo DL (1994) Phosphorylation of NF-kB1-p50 is involved in NF-kB activation and stable DNA binding. Journal of Biological Chemistry 269 30089-30092
Li C-C H, Ruscetti FW, Rice NR, Chen E, Yang N-S, Mikovits J and Longo DL (1993) Differential expression of Rel family members in human T-cell leukemia virus type I-infected cells: transcriptional activation of c-rel by Tax protein. Journal of Virology 67 4205-4213
Li C-CH, Korner M, Ferris DK, Chen E, Dai R-M and Longo DL (1994) NF-kB/Rel family proteins are physically associated phosphoproteins. Biochemical Journal 303 499-506
Li CH, Wang JH and Redmond HP (2006) Bacterial lipoprotein-induced self-tolerance and cross-tolerance to LPS are associated with reduced IRAK-1 expression and MyD88-IRAK complex formation. Journal of Leukocyte Biology in press
Li CJ, Dezube BJ, Biswas DK, Ahlers CM and Pardee AB (1994) Inhibitors of HIV-1 transcription. Trends in Microbiology 2 164-169
Li CL, Wang XY, Shao J, Zhang JS, Feng WG, Wang YB and Chang ZL (2002) Heat shock inhibits IL-12 p40 expression through NF-kB signalling pathway in murine macrophages. Cytokine 16 153-159
Li CY, Li L, Li YH, Ai HX and Zhang L (2005) Effects of extract from Cornus officinalis on nitric oxide and NF-kB in cortex of cerebral infarction rat model [Article in Chinese]. Zhongguo Zhong Yao Za Zhi 30 1667-1670
Li CY, Zhan YQ, Xu CW, Xu WX, Wang SY, Lv J, Zhou Y, Yue PB, Chen B and Yang XM (2004) EDAG regulates the proliferation and differentiation of hematopoietic cells and resists cell apoptosis through the activation of nuclear factor-kB. Cell Death & Differentiation 11 1299-1308
Li D (2006) Selective degradation of the IkappaB kinase (IKK) by autophagy. Cell Research 16 855-856
Li D and Mehta JL (2000) Upregulation of endothelial receptor for oxidized LDL (LOX-1) by oxidized LDL and implications in apoptosis of human coronary artery endothelial cells: evidence from use of antisense LOX-1 mRNA and chemical inhibitors. Arteriosclerosis, Thrombosis, Vascular Biology 20 1116-1122
Li D, Saldeen T and Mehta JL (1999) gamma-tocopherol decreases ox-LDL-mediated activation of nuclear factor-kB and apoptosis in human coronary artery endothelial cells. Biochemical and Biophysical Research Communications 259 157-161
Li D and Taylor AW (2008) Diminishment of {alpha}-MSH anti-inflammatory activity in MC1r siRNA-transfected RAW264.7 macrophages. Journal of Leukocyte Biology in press
Li DH, Kumanogoh A, Cao TM, Parnes JR and Cullen JM (2004) Woodchuck interleukin-6 gene: structure, characterization, and biologic activity. Gene 342 157-164
Li DH, Tung JW, Tarner IH, Snow AL, Yukinari T, Ngernmaneepothong R, Martinez OM and Parnes JR (2006) CD72 down-modulates BCR-induced signal transduction and diminishes survival in primary mature B lymphocytes. Journal of Immunology 176 5321-5328
Li G, Aaron S, Kazmierczak K, Lesner A, Li Y, Ivanova A, Bentsman G, Potash MJ and SImm M (2007) Inhibition of HIV-1 or bacterial activation of macrophages by products of HIV-1-resistant human cells. Immunology and Cell Biology in press
Li G, Dong B, Butz DE, Park Y, Pariza MW and Cook ME (2006) NF-kB independent inhibition of lipopolysaccharide-induced cyclooxygenase by a conjugated linoleic acid cognate, conjugated nonadecadienoic acid. Biochimica et Biophysica Acta1761 969-972
Li G, Labruto F, Sirsjo A, Chen F, Vaage J and Valen G (2004) Myocardial protection by remote preconditioning: the role of nuclear factor kappa-B p105 and inducible nitric oxide synthase. European Journal of Cardiothoracic Surgery 26 968-973
Li G, Lubin FD and McGee DW (2004) alpha3beta1 integrin induced suppression of the Caco-2 epithelial cell IL-1 signaling pathway leading to NF-kB activation.Cellular Immunology 231 30-39
Li G, Luna C, Liton PB, Navarro I, Epstein DL and Gonzalez P (2007) Sustained stress response after oxidative stress in trabecular meshwork cells. Molecular Vision 13 2282-2288
Li G, Qi XP, Wu XY, Liu FK, Xu Z, Chen C, Yang XD, Sun Z and Li JS (2006) Verapamil modulates LPS-induced cytokine production via inhibition of NF-kB activation in the liver. Inflammation Research 55 108-113
Li GP, Liu ZG, Zhong NS, Liao B and Xiong Y (2006) Therapeutic effects of DNA vaccine on allergen-induced allergic airway inflammation in mouse model.Cellular & Molecular Immunology 3 379-384
Li H, Cai X, Fan X, Moquin B, Stoicov C and Houghton J (2007) Fas Ag/Fas L coupling leads to ERK 1/2 mediated proliferation of gastric mucosal cells. American Journal of Physiology: Gastrotinerinal Liver Physiology in press
Li H, Chehade M, Liu W, Xiong H, Mayer L and Berin MC (2007) Allergen-IgE complexes trigger CD23-dependent CCL20 release from human intestinal epithelial cells. Gastroenterology 133 1905-1915
Li H, Cuartas E, Cui W, Choi Y, Crawford TD, Ke HZ, Kobayashi KS, Flavell RA and Vignery A (2005) IL-1 receptor-associated kinase M is a central regulator of osteoclast differentiation and activation. Journal of Experimental Medicine 201 1169-1177
Li H, Gao L, Shen Z, Li CY, Li K, Li M, Lv YJ, Li CX, Gao TW and Liu YF (2008) Association study of NFKB1 and SUMO4 polymorphisms in Chinese patients with psoriasis vulgaris. Archives of Dermatological Research in press
Li H, Gu H and Sun B (2007) Protective effects of pyrrolidine dithiocarbamate on myocardium apoptosis induced by adriamycin in rats. International Journal ofCardiology 114 159-165
Li H, Kobayashi M, Blonska M, You Y and Lin X (2006) Ubiquitination of RIP is required for TNFa-induced NF-kB activation. Journal of Biological Chemistry 281 13636-13643
Li H, Li X, Duan L and Li C (2003) Inhibition of lovastatin on proliferation and expression of proinflammatory cytokines in cultured human glomerular mesangial cells. Chinese Medical Journal (English) 116 1366-1369
Li H and Lin X (2007) Positive and negative signaling components involved in TNFa-induced NF-kB activation. Cytokine in press
Li H, Malhotra S and Kumar A (2008) Nuclear factor-kB signaling in skeletal muscle atrophy. Journal of Molecular Medicine in press
Li H, Rajendran GK, Lin N, Ware C, Rubin BP and Gu Y (2007) SirT1 modulates the estrogen-IGF-1 signaling for postnatal development of mammary gland in mice.Breast Cancer Research 9 R1
Li H, Ren CP, Tan XJ, Yang XY, Zhang HB, Zhou W and Yao KT (2006) Identification of genes related to nasopharyngeal carcinoma with the help of pathway-based networks. Acta Biochimica Biophysica Sinica (Shanghai) 38 900-910
Li H, Ruan XZ, Powis SH, Fernando R, Mon WY, Wheeler DC, Moorhead JF and Varghese Z (2005) EPA and DHA reduce LPS-induced inflammation responses in HK-2 cells: Evidence for a PPAR-g-dependent mechanism. Kidney International 67 867-874
Li H, Ye X, Mahanivong C, Bian D, Chun J and Huang S (2005) Signaling mechanisms responsible for lysophosphatidic acid-induced urokinase plasminogen activator expression in ovarian cancer cells. Journal of Biological Chemistry 280 10564-10571
Li H, Yin H, Zhang H, Cao X, Wang Z and She M (2002) Effect of NF-kB on the induction of PDGF-B transcription by angiotensin II in the ECV304 cell line. Chinese Medical Journal (Engl) 115 433-438
Li H, Yin H, Zhang H, Wang Z and She M (2001) Activation of NF-kB and its effect on induction of platelet-derived growth factor-B transcription by angiotensin II in ECV304 cell line [Article in Chinese]. Zhonghua Bing Li Xue Za Zhi 30 276-280
Li H, Zhang J, Kumar A, Zheng M, Atherton SS and Yu FS (2006) Herpes simplex virus 1 infection induces the expression of proinflammatory cytokines, interferons and TLR7 in human corneal epithelial cells. Immunology 117 167-176
Li H, Zhu Zl, Jia N, Bai ZL, Cai Q, Chen R, Song TB and Liu JK (2006) Gender-dependent difference of NF-kB expression in the hippocampus of prenatally stressed offspring rats [Article in Chinese]. Sheng Li Xue Bao 58 577-583
Li HJ, Yin H, Yao YY, Shen B, Bader M Chao L and Chao J (2006) Tissue kallikrein protects against pressure overload-induced cardiac hypertrophy through kinin B2 receptor and glycogen synthase kinase-3beta activation. Cardiovascular Research in press
Li HL, Chen HL, Li H, Zhang KL, Chen XY, Wang XW, Kong QY and Liu J (2005) Regulatory effects of emodin on NF-kB activation and inflammatory cytokine expression in RAW 264.7 macrophages. International Journal of Molecular Medicine16 41-47
Li HL, Huang Y, Zhang CN, Liu G, Wei YS, Wang AB, Liu YQ, Hui RT, Wei C, Williams GM, Liu DP and Liang CC (2006) Epigallocathechin-3 gallate inhibits cardiac hypoertrophy through blocking reactive oxidative species-dependent and -independent signal pathways. Free Radical Biology and Medicine 40: 1756-1775
Li HL, Liu C, de Couto G, Ouzounian M, Sun M, Wang AB, Huang Y, He CW, Shi Y, Chen X, Nghiem MP, Liu Y, Chen M, Dawood F, Fukuoka M, Maekawa Y, Zhang L, Leask A, Ghosh AK, Kirschenbaum LAA and Liu PP (2008) Curcumin prevents and reverses murine cardiac hypertrophy. Journal of Clinical Investigation in press
Li HL, Liu B, Zhou LW and Yu WH (2005) Change and significance of nuclear factor-kB in adriamycin induced cardiomyopathy in rats. Chinese Medical Journal (English) 118 111-115
Li HL, Wang AB, Huang Y, Liu DP, Wei C, Williams GM, Zhang CN, Liu G, Liu YQ, Hao DL, Hui RT, Lin M and Liang CC (2005) Isorhapontigenin, a new resveratrol analog, attenuates cardiac hypertrophy via blocking signaling transduction pathways. Free Radical Biology and Medicine 38 243-257
Li HL, Wang AB, Zhang R, Wei YS, Chen HZ, She ZG, Huang Y, Liu DP and Liang CC (2006) A20 inhibits oxidized low-density lipoprotein-induced apoptosis through negative Fas/Fas ligand-dependent activation of caspase-8 and mitochondrial pathways in murine RAW264.7 macrophages. Journal of Cellular Physiology in press
Li HL, Yin R, Chen D, Liu D, Wang D, Yang Q and Dong YG (2007) Long-term activation of adenosine monophosphate-activated protein kinase attenuates pressure-overload-induced cardiac hypertrophy. Journal of Cellular Biochemistry in press
Li HM, Man C, Jin Y, Deng W, Yip YL, Feng HC, Cheung YS, Lo KW, Meltzer PS, Wu ZG, Kwong YL, Yuen AP and Tsao SW (2006) Molecular and cytogenetic changes involved in the immortalization of nasopharyngeal epithelial cells by telomerase. Interntational Journal of Cancer in press
Li HM, Zhuang ZH, Wang Q, Pang JC, Wang XH, Wong HL, Feng HC, Jin DY, Ling MT, Wong YC, Eliopoulos AG, Young LS, Huang DP and Tsao SW (2004) Epstein-Barr virus latent membrane protein 1 (LMP1) upregulates Id1 expression in nasopharyngeal epithelial cells. Oncogene 23 4488-4494
Li HY, Liu H, Wang CH, Zhang JY, Man JH, Gao YF,, Zhang PJ, Li WH, Zhao J, Pan X, Zhou T, Gong WL, Li AL and Zhang XM (2008) Deactivation of the kinase IKK by CUEDC2 through recruitment of the phosphatase PP1. Nature Immunology in press
Li HZ, Cao JG, Deng YA, Su JH and Xie WY (2007) Induction of apoptosis of human ovarian cancer CoC1 cells by 5-allyl-7-gen-difluoromethylenechrysin through activation of peroxisome-proliferator activated receptor-gamma {Article in Chinese]. Zhonghua Yi Xue Za Zhi 87 2914-2918
Li J and Brasier AR (1996) Angiotensinogen gene activation by angiotensin II is mediated by the rel A (nuclear factor-kB p65) transcription factor: one mechanism for the renin angiotensin system positive feedback loop in hepatocytes. Molecular Endocrinology 10 252-264
Li J, Chen H, Ke Q, Feng Z, Tang MS, Liu B, Amin S, Costa M and Huang C (2004) Differential effects of polycyclic aromatic hydrocarbons on transactivation of AP-1 and NF-kB in mouse epidermal cl41 cells. Molecular Carcinogenesis 40 104-115
Guo J, Guo M, Hu B, Liu R, Wang R and Tang C (2008) Does chronic ethanol intake cause chronic pancreatitis?: evidence and mechanism. Pancrease 37 189-195
Li J, Johnson XD, Iasvovskaia S, Tan A, Lin A and Hershenson MB (2002) Signaling intermediates required for NF-kB activation and IL-8 expression in CF bronchial epithelial cells. American Journal of Physiology: Lung Cellular and Molecular Physiology 284 L307-L315
Li J, Joo SH and Tsai MD (2003) An NF-kB-specific inhibitor, IkBa, binds to and inhibits cyclin-dependent kinase 4. Biochemistry 42 13476-13483
Li J, Kartha S, Iasvovskaia S, Tan A, Bhat RK, Manaligod JM, Page K, Brasier AR and Hershenson MB (2002) Regulation of human airway epithelial cell IL-8 expression by MAP kinases. American Journal of Physiology: Lung Cellular and Molecular Physiology 283 L690-L699
Li J, Li Q, Xie C, Zhou H, Wang Y, Zhang N, Shao H, Chan SC, Peng X, Lin SC and Han J (2004) beta-actin is required for mitochondria clustering and ROS generation in TNF-induced, caspase-independent cell death. Journal of Cell Science 117 4673-4680
Li J, Liu Z, Jiang S, Cortesini R, Lederman S and Suciu-Foca N (1999) T suppressor lymphocytes inhibit NF-kB-mediated transcription of CD86 gene in APC. Journal of Immunology 163 6386-6392
Li J, Lu Z, Li WL, Yu SP and Wei L (2008) Cell death and proliferation in NF-kB p50 knockout mouse after cerebral ischemia. Brain Research in press
Li J, Ma Z, Tang ZL, Stevens T, Pitt B and Li S (2004) CpG DNA-mediated immune response in pulmonary endothelial cells. American Journal of Physiology: Lung Cellular and Molecular Physiology 287 L552-558
Li J, Ma Z, Blythe SP and Castillo-Chavez C (2003) Coexistence of pathogens in sexually-transmitted disease models. Journal of Mathematical Biology 47 547-568
Li J, Minnich DJ, Camp ER, Brank A, Mackay SL and Hochwald SN (2006) Enhanced sensitivity to chemotherapy in esophageal cancer through inhibition of NF-kB.Journal of Surgical Research 11332 112-120
Li J, Moran T, Swanson E, Julian C, Harris J, Bonen DK, Hedl M, Nicolae DL, Abraham C and Cho JH (2004) Regulation of IL-8 and IL-1{beta} expression in Crohn’s disease associated NOD2/CARD15 mutations. Human Molecular Genetics 13 1715-1725
Li J, Peet GW, Balzarano D, Li X, Massa P, Barton RW and Marcu KB (2001) Novel NEMO/IkB kinase and NF-kB target genes at the pre-B to immature B cell transition. Journal of Biological Chemistry 276 18579-18590
Li J, Quan N and Bray TM (2002) Supplementation of N-acetylcysteine normalizes lipopolysaccharide-induced nuclear factor kappaB activation and proinflammatory cytokine production during early rehabilitation of protein malnourished mice. Journal of Nutrition 132 3286-3292
Li J, Shen J adn Beurman RW (2007) Expression of toll-like receptors in human limbal and conjunctival epithelial cells.
Molecular Vision 13 813-822
Li J, Vesey DA, Johnson DW and Gobe G (2007) Erythropoietin reduces cisplatin-induced apoptosis in renal carcinoma cells via a PKC dependent pathway. Cancer Biology Therapeutics in press
Li J, Wu M, Que L, Wang Y, Xu X< Hu Y, Ha T, Li C, Chen Q and Li Y (2008) 17beta-estradiol attenuates cardiac dysfunction and decreases NF-kB binding activity in mechanically stretched rat hearts. Steroids in press
Li J, Zelenin S, Aperia A and Aizman O (2006) Low doses of ouabain protect from serum deprivation-triggered apoptosis and stimulate kidney cell proliferation via activation of NF-kB.
Journal of the American Society of Nephrology 60 377-381
Li J, Zhang D, Stoner GD and Huang C (2007) Differential effects of black raspberry and strawberry extracts on BaPDE-induced activation of transcription factors and their target genes. Molecular Carcinogenesis in press
Li J, Zhou H, Cai Q and Xiao G (2002) Activation of NF-kB and apoptosis of intestinal epithelial cells induced by hydrogen peroxide. Chinese Journal of Traumatology 5 209-213
Li J, Zuo L, Shen T and Zhang ZN (2002) Inhibition of the activation of transcriptional factor NFkB during sodium selenite-induced apoptosis in NB4 cells {Article in Chinese]. Zhongguo Shi Yan Xue Ye Xue Za Zhi 10 409-412
Li JC, Chang L, Lu D, Jiang DJ and Tan DM (2007) Effect of asymmetric dimethylarginine on the activation of hepatic stellate cells and its mechanism [Article in Chinese]. Zhong Nan Da Xue Xue Bao Yi Xue B 32 427-432
Li JD (2003) Exploitation of host epithelial signaling networks by respiratory bacterial pathogens. Journal of Pharmacological Sciences 91 1-7
Li JG, Hu ZF, Du ZH, Zhou Q, Jia BH, Peng ZQ, Ye XF and Li B (2005) Protective effect of the cholinergic anti-inflammatory pathway against hemorrhagic shock in rats [Article in Chinese]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 17 24-27
Li JH, Kirkiles-Smith NC, McNiff JM and Pober JS (2003) TRAIL induces apoptosis and inflammatory gene expression in human endothelial cells. Journal of Immunology 171 1526-1533
Li JH, Yu JP, Yu HG, Xu XM, Yu LL and Liu SQ (2005) Expression and significance of nuclear factor kB p65 in colon tissues of rats with TNBS-induced colitis. World Journal of Gastroenterology 11 1759-1763
Li JH, Yu JP, Yu HG, Xu XM, Yu LL, Liu J and Luo HS (2005) Melatonin reduces inflammatory injury through inhibiting NF-kB activation in rats with colitis.Mediators of Inflammation 2005 185-193
Li JJ and Fang CH (2004) C-reactive protein is not only an inflammatory marker but also a direct cause of cardiovascular diseases. Medical Hypotheses 62 499-506
Li JJ and Gao RL (2005) Should atherosclerosis be considered a cancer of the vascular wall? Medical Hypotheses 64 694-698
Li JJ, Oberly LW, Fan M and Colburn NH (1998) Inhibition of AP-1 and NF-kB by manganese-containing superoxide dismutase in human breast cancer cells. FASEB Journal 12 1713-1723
Li JJ, Rhim JS, Schlegel R, Vousden KH and Colburn NH (1998) Expression of dominant negative Jun inhibits elevated AP-1 and NF-kB transactivation and suppresses anchorage independent growth of HPV immortalized human keratinocytes. Oncogene 16 2711-2721
Li JL, Chen HM, Li ML, Hua D, Lu ZH and Wang JK (2006) An optimized assay for transcription factor NF-kB with dsDNA-coupled microplate. Colloids and Surfaces.B, Biointerfaces 55 31-37
Li J-M, Shen X, Hu PP-C and Wang X-F (1998) Transforming growth factor b stimulates the human immunodeficiency virus 1 enhancer and requires NF-kB activity. Molecular and Cellular Biology 18 110-121
Li JY, Lai YJ, Yeh HI, CHen CL, Sun S, Wu SJ and Lin FY (2008) Atrial gap junctions, NF-kB and fibrosis in patients undergoing coronary artery bypass surgery: the relationship with postoperative atrial fibrillation. Cardiology 112 81-88
Li K, Foy E, Ferreon JC, Nakamura M, Ferreon AC, Ikeda M, Ray SC, Gale M Jr and Lemon SM (2005) Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF. Proceedings of the National Academy of Sciences USA in press
Li KL, Zhang JG, Wang HM and Chen J (2004) The effects of glycyrrhizin-18alpha on the expression of NF-kB in the renal interstitium of rats with obstructive nephropathy [Article in Chinese]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 20 31-33
Li L (2004) Regulation of innate immunity signaling and its connection with human diseases. Current Drug Targets in Inflammation and Allergy 3 81-86
Li L, Aggarwal BB, Shishodia S, Abbruzzese J and Kurzrock R (2004) Nuclear factor-kB and IkB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis. Cancer 101 2351-2362
Li L, Asterious T, Bernert B, Heldin CH and Heldin P (20070 Growth factor regulation of hyaluronan synthesis and degradation in human dermal fibroblasts: Importance of hyaluronan for the mitogenic response of PDGF-BB. BiochemicalJournal in press
Li L, Bin LH, Li F, Liu Y, Chen D, Zhai Z and Shu HB (2005) TRIP6 is a RIP2-associated common signaling component of multiple NF-kB activation pathways. Journal of Cell Science 118 555-563
Li L, Braiteh FS and Kurzrock R (2005) Liposome-encapsulated curcumin. Cancer 104 1322-1331
Li L, Gao XL and Ding BX (2008) Inhibitory effect of sinomenine on H2O2-induced apoptosis in neonatal rat cardiomyocytes [Aritcle in Chinese]. Zhongguo Zhong Yao Za Zhi 33 939-941
Li L, Gondi CS, Dinh DH, Olivero WC, Gujrai M and Rao JS (2007) Transfection with anti-p65 intrabody suppresses invasion and angiogenesis in glioma cells by blocking nuclear factor-kB transcriptional activity. Clinical Cancer Research 13 2178-2190
Li L, Hailey DW, Soetandyo N, Li W, Lippincott-Schwartz J, Shu HB and Ye Y (2008) Localization of A20 to a lysosome-associated compartment and its role in NFkB signaling. Biochmica et Biophysica Acta inp ress
Li L, Hamilton Jr RF and Holian A (1999) Effect of acrolein on human alveolar macrophage NF-kB activity. American Journal of Physiology 277 L550-L557
Li L and Frei B (2006) Iron chelation inhibits NF-kB-mediated adhesion molecule expression by inhibiting p22phox protein expression and NADPH oxidase activity.Arteriosclerosis, Thrombosis and Vascular Biology 26 2638-2643
Li L, Mamputa JC, Wiernsperger N and Renier G (2005) Signaling pathways involved in human vascular smooth muscle cell proliferation and matrix metalloproteinase-2 expression induced by leptin: inhibitory effect of metformin. Diabetes 54 2227-2234
Li L, Prabhakaran K, Zhang X, Zhang L, Liu H, Borowitz JL and Isom GE (2008) 1alpha,25-dihydroxyvitamin D(3) attenuates cyanide-induced neurotoxicity by inhibiting uncoupling protein-2 up-regulation. Journal of Neuroscience Research in press
Li L, Rao JN, Bass BL and Wang JY (2001) NF-kB activation and susceptibility to apoptosis after polyamine depletion in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol 280 G992-G1004
Li L, Rossoni B, Sparatore A, Lee LC, Del Soldato P and Moore PK (2007) Anti-inflammatory and gastrointestinal effects of a novel diclofenac derivative. Free Radical Biology and Medicine 42 706-719
Li L, Sawamura T and Renier G (2003) Glucose enhances endothelial LOX-1 expression: role for LOX-1 in glucose-induced human monocyte adhesion to endothelium. Diabetes 52 1843-1850
Li L, Sawamura T and Renier G (2004) Glucose enhances human macrophage LOX-1 expression. Role for LOX-1 in glucose-induced macrophage foam cell formation. Circulation Research 94 892-901
Li L, Song GW, DU JB, Liu JR, Xu FS, Liu XY and Zhang T (2005) NEMODelta4-10 deletion of NEMO gene in Chinese incontinentia pigmenti cases [Article in Chinese]. Zhonghua Er Ke Za Zhi 43 89-92
Li L, Su J and Xie Q (2007) Differential reguation of key signaling moleculaes in innatue immunity and human diseases. Advances in Experimental Medicine and Biology 598 49-61
Li L, Thomas RM, Suzuki H, De Brabander JK, Wang X and Harran PG (2004) A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death. Science 305 1471-1474
Li L, Wang XP and Wu K (2004) The therapeutic effect of oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine in mice with acute necrotizing pancreatitis [Article in Chinese]. Zhonghua Yi Xue Za Zhi 84 1235-1239
Li L, Wang XP and Wu K (2007) The therapeutic effect of oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine in rodents with acute necrotizing pancreatitis and its mechanism.
Pancreas 35 e27-e36
Li L and Wu LL (2004) Development and application of NF-kB decoy oligodeoxynucleiotide [Article in Chinese]. Sheng Li Ke Xue Jin Zhan 35 163-166
Li LB, Toan SV, Zelenaia O, Watson DJ, Wolfe JH, Rothstein JD and Robinson MB (2006) Regulation of astrocytic glutamate transporter expression by Akt: evidence for a selective transcriptional effect on the GLT-1/EAAT2 subtype.Journal of Neurochemistry in press
Li LC, Shen F, Hou Q and Cheng GF (2002) Inhibitory effect and mechanism of action of sanggenon C on human polymorphonuclear leukocyte adhesion to human synovial cells. Acta Pharmacol Sin 23 138-142
Li LF, Ouyang B, Choukroun G, Matyal R, Mascarenhas M, Jafari B, Bonventre JV, Force T and Quinn DA (2003) Stretch-induced IL-8 depends on c-Jun N-terminal and nuclear factor-kB-inducing kinases. American Journal of Physiology: Lung Cell and Molecular Physiology 285 L464-L475
Li LH, Wu LJ, Tashiro SI, Onodera S, Uchiumi F and Ikejima T (2006) The roles of Akt and MAPK family members in silymarin’s protection against UV-induced A375-S2 cell apoptosis. International Immunopharmacology 6 190-197
Li LY, Zhao XL, Fei XF, Gu ZL, Qin ZH and Liang ZQ (2008) Bilobalide inhibits 6-OHDA-induced activation of NF-kB and loss of dopaminergic neurons in rat substantia nigra. Acta Pharmalogica Sinica 29 539-547
Li M, Cai JF and Chiu JF (2002) Arsenic induces oxidative stress and activates stress gene expressions in cultured lung epithelial cells. Journal of Cellular Biochemistry 87 29-38
Li M, Carpio DF, Zheng Y, Bruzzo P, Singh V, Ouaaz F, Medzhitov RM and Beg AA (2001) An essential role of the NF-kB/Toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells. Journal of Immunology 166 7128-7135
Li M, Chiou KR, Bugayenko A, Irani K and Kass DA (2005) Reduced wall compliance suppresses Akt-dependent apoptosis protection stimulated by pulse perfusion. Circulation Research 97 587-595
Li M, Cortez S, Nakamachi T, Batuman V and Arimura A (2006) Pituitary adenylate cyclase-activating polypeptide is a potent inhibitor of the growth of light chain-secreting human multiple myeloma cells. Cancer Research 66 8796-8803
Li M, Feng S, adn Wu M (2008) Multiple roles for nuclear localization signal (NLS, aa 442-472) of receptor interacting protein 3 (RIP3). Biochemical and Biophysical Research Communications in press
Li M, Shillinglaw W, Henzel WJ and Beg AA (2001) The Rela(p65) subunit of NF-kB is essential for inhibiting double- stranded RNA-induced cytotoxicity. Journal of Biological Chemistry 276 1185-1194
Li M, Yang Q and Zhang Y (2007) Effects of CD134 monoclonal antibody on hemolysis activities and expression of perforin in peripheral blood mononuclear cells of systemic lupus erythematosus patients. Hybridoma (Larchmt) 26 191-200
Li M, Zhang X, Zheng X, Lian D, Zhang ZX, Ge W, Yang J, Vladau C, Suzuki M Chen D, Zhong R, Garcia B, Jevnikar AM and Min WP (2007) Immune modulation and tolerance induction by RelB-silenced dendritic cells through RNA interference.Journal of Immunology 178 5480-5487
Li MH, Jang JH, Sun B and Surh YJ (2004) Protective effects of oligomers of grape seed polyphenols against b-amyloid-induced oxidative cell death. Annals of the New York Academy of Sciences 1030 317-329
Li MJ, Li JJ, Zhao XB, Zhang MJ and Wang W (2005) Influence of mifepristone and lilopristone on proliferation and expression of nuclear factor-kB of ectopic stromal cells in vitro [Article in Chinese]. Zhonghua Fu Chan Ke Za Zhi 40 21-24
Li MY, Yip J, Hsin MK, Mok TS, Wu Y, Underwood MJ and Chen GG (2008) HO-1 plays a central role in NNK-mediated lung carcinogenesis. European Respiratory Journal in press
Li N and Karin M (1998) Ionizing radiation and short wavelength UV activate NF-kB through two distinct pathways. Proceedings of the National Academy of Sciences USA 95 13012-13017
Li N and Karin M (1999) Is NF-kB the sensor of oxidative stress. FASEB Journal 13 1137-1143
Li N, Banin S, Ouyang H, Li GC, Courtois G, Shiloh Y, Karin M and Rotman G (2000) ATM is required for IkB kinase (IKKk) activation in response to DNA double strand breaks. Journal of Biological Chemistry 276 8898-8903
Li P, Mane SP, Sioson AA, Robinet CV, Heath LS, Bohnert HJ and Grene R (2006) Effects of chronic ozone exposure on gene expression in Arabidopsis thaliana ecotypes and in Thellungiella halophila. Plant Cell Environ 29 854-868
Li PC, Li SC, Lin YJ, Liang JT, Chien CT and Shaw CF (2005) Thoracic vagal efferent nerve stimulation evokes substance P-induced early airway bronchonstriction and late proinflammatory and oxidative injury in the rat respiratory tract. Journal of Biomedical Science 12 671-681
Li Q, Carr AL, Donald EJ, Skitzki JJ, Okuyama R, Stoolman LM and Chang AE (2005) Synergistic effects of IL-12 and IL-18 in skewing tumor-reactive T-cell responses towards a type 1 pattern. Cancer Research 65 1063-1070
Li Q and Cherayil BJ (2003) Role of Toll-like receptor 4 in macrophage activation and tolerance during Salmonella enterica Serovar typhimurium infection. Infection and Immunity 71 4873-4882
Li Q, Ching AK, Chan BC, Chow SK, Lim PL, Ho TC, Ip WK, Wong CK, Lam CW, Lee KK, Chan JY and Chui YL (2004) A death receptor-associated antiapoptotic protein, BRE, inhibits mitochondrial apoptotic pathway. Journal of Biological Chemistry 279 52106-52116
Li Q and Engelhardt JF (2006) Interleukin-1beta induction of NFkB is partially regulated by H2O2-mediated activation of NFkB-inducing kinase. Journal of Biological Chemistry 281 1495-1505
Li Q, Estepa G, Memet S, Israel A and Verma IM (2000) Complete lack of NF-kB activity in IKK1 and IKK2 double-deficient mice:additional defect in neurulation. Genes & Development 14 1729-1733
Li Q, Guo Y, Tan W, Ou Q, Wu WJ, Sturza D, Dawn B, Hunt G, Cui C and Bolli R (2007) Cardioprotection afforded by inducible nitric oxide synthase gene therapy is mediated by cyclooxygenase-2 via a nuclear factor-kB dependent pathway.
Circulation in press
Li Q, Harraz MM, Zhou W, Zhang LN, Ding W, Zhang Y, Eggleston T, Yeaman C, Banfi B and Engelhardt JF (2006) Nox2 and Rac1 regulate H2O2-dependent recruitment of TRAF6 to endosomal interleukin-1 receptor complexes. Molecular and Cellular Biology 26 140-154
Li Q, Kumar A, Gui JF and Yu FS (2007) Staphylococcus aureus lipoproteins trigger human corneal epithelial innate response through toll-like receptor-2. Microbial Pathogenesis in press
Li Q, Laumonnier Y, Syrovets T and Simmet T (2007) Plasmin triggers cytokine induction in human monocyte-derived macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology in press
Li Q, Lu Q, Bottero V, Estepa G, Morrison L, Mercurios F and Verma IM (2005) Enhanced NF-kB activation and cellular function in macrophages lacking IkB kinase 1 (IKK1). Proceedings of the National Academy of Sciences USA 102 12425-12430
Li Q, Lu Q, Hwang JY, Buscher D, Lee KF, Izpisua-Belmonte JC and Verma IM (1999) IKK1-deficient mice exhibit abnormal development of skin and skeleton. Genes & Development 13 1322-1328
Li Q, Vaingankar SM, Green HM and Martins-Green M (1999) Activation of the 9E3/cCAF chemokine by phorbol esters occurs via multiple signal transduction pathways that converge to MEK1/ERK2 and activate the Elk1 transcription factor. Journal of Biological Chemistry 274 15454-15465
Li Q, Van Antwerp D, Mercurio F, Lee K-F and Verma IM (1999) Severe liver degeneration in mice lacking the IkB kinase 2 gene. Science 284 321-325
Li Q and Verma IM (2002) NF-kB regulation in the immune system. Nature Reviews Immunology 2 725-734
Li Q, Withoff S and Verma IM (2005) Inflammation-associated cancer: NF-kB is the lynchpin. Trends in Immunology 26 318-325
Li Q, Yu YY, Zhu ZG, Ji YB, Zhang Y, Liu BY, Chen XH and Lin YZ (2005) Effect of NF-kB constitutive activation on proliferation and apoptosis of gastric cancer cell lines. European Surgical Research 37 105-110
Li Q, Zhang Y, Marden JJ< Banfi B adn Engelhardt JF (2008) Endosomal NADPH oxidase regulates c-Src activation following hypoxia/reoxygenation injury. Biochemical Journal 411 531-541
Li QQ, Burt DR and Bever CT (2001) Glatiramer acetate inhibition of tumor necrosis factor-alpha-induced RANTES expression and release from U-251 MG human astrocytic cells. Journal of Neurochemistry 77 1208-1217
Li R, Yang L, Lindholm K, Konishi Y, Yue X, Hampel H, Zhang D and Shen Y (2004) Tumor necrosis factor death receptor signaling cascade is required for amyloid-beta protein-induced neuron death. Journal of Neuroscience 24 1760-1771
Li RW, Man RY, Vanoutte PM and Leung GP (2008) Stimulation of ecto-5’nucleotidase in human umbilical vein endothelial cells by lipopolysaccharide. American Journal of Physiology: Heart and Circulatory Physiology in press
Li S and Bobek LA (2006) Functional analysis of human MUC7 mucin gene 5′-flanking region in lung epithelial cells. American Journal of Respiratory Celland Molecular Biology 35 593-601
Li S, E M and Yu B (2007) Adriamycin induces myocardium apoptosis through activation of nuclear factor kB in rat.
Molecular Biology Reports in press
Li S, Gokden N, Okusa MD, Bhatt R and Portilla D (2005) Anti-inflammatory effect of fibrate protects from cisplatin-induced ARF. American Journal of Physiology: Renal Physiology 289 F469-F480
Li S, Ni Z, Cong B, Gao W, Xu S, Wang C, Yao Y, Ma C adn Ling Y (2007) CCK8 inhibits LPS-induced IL-1b production in pulmonary interstitial macrophages by modulating PKA, p38 and NF-kB pathway. Shock 27 678-686
Li S and Sedivy JM (1993) Raf-1 protein kinase activates the NF-kB transcription factor by dissociating the cytoplasmic NF-kB-IkB complex. Proceedings of the National Academy of Sciences USA 90 9247-9251
Li S and Shang Y (2007) Regulation of SRC family coactivators by post-translational modifications. Cellular Signaling in press
Li S and Stark G (2002) NFkB-dependent signaling pathways. Experimental Hematology 30 285-296
Li S, Wang L, Berman MA, Zhang Y and Dorf ME (2006) RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kB signaling. Molecular Cell24 497-509
Li S, Wang X, Qiu J, Si Q, Wang H, Guo H, Sun R and Wu Q (2005) Angiotensin II stimulates endothelial integrin beta(3) expression via nuclear factor-kB activation. Experimental Aging Research 32 47-60
Li S, Yan T, Yang JQ, Oberley TD, Oberley LW (2000) The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase. Cancer Research 60 3927-3939
Li S, Zhang Y and Zhao J (2007) Preparation and suppressive effect of astragalus polysaccharide in glomerulonephritis rats.
International Immunopharmacology 7 23-28
Li SF, Fujita F, Hirai M, Lu R, Niida H and Nakanishi M (2003) Genomic structure and characterization of the promoter region of the human NAK gene. Gene 307 57-64
Li SL, Reddy MA, Cai Q, Meng L, Yuan H, Lanting L and Natarajan R (2006) Enhanced proatherogenic responses in macrophages and vascular smooth muscle cells derived from diabetic db/db mice. Diabetes 55 2611-2619
Li SM, Wang XM, Qiu J, Si Q, Guo HY, Sun RY and Wu QX (2005) Inhibitory effects of alpha-zearalenol on angiotensin II-induced integrin beta3 mRNA via suppression of nuclear factor-kappaB.
Biomedical and Environmental Sciences 18 314-320
Li T, Hu J and Li L (2004) Characterization of Tollip protein upon lipopolysaccharide challenge. Molecular Immunology 41 85-92
Li T, Narhi LO, Wen J, Philo JS, Sitney K, Inoue J, Yamamoto T and Arakawa T (1998) Interactions between NFkB and its inhibitor IkB: biophysical characterization of a NFkB/IkB-a complex. Journal of Protein Chemistry 17 757-763
Li T, Narhi LO, Wen J, Philo JS, Sitney K, Inoue J, Yamamoto T and Arakawa T (1998) Interactions between NFkB and its inhibitor IkB: biophysical characterization of a NFkB/IkB-a complex. Journal of Protein Chemistry 17 757-763
Li T, Southall MD, Yi Q, Pei Y, Lewis D, Al-Hassani M, Spandau D and Travers JB (2003) The epidermal platelet-activating factor receptor augments chemotherapy-induced apoptosis in human carcinoma cell lines. Journal of Biological Chemistry 278 16614-16621
Li TJ, Jia LP, Gao XL and Huang AL (2006) Gene therapy that inhibits NF-kB results in apoptosis of human hepatocarcinoma by recombinant adenovirus. World Journal of Gastroenterology 12 5287-5292
Li TL, Li Y, Zhang GH, Sun YN and Li YQ (2004) Expression and DNA binding activity of NF-kB in mucosal tissue of chronic rhinosinusitis [Article in Chinese]. Zhonghua Er Bi Yan Hou Ke Za Zhi 39 489-492
Li W, Bengtson MH, Ulbrich A, Matsuda A, Reddy VA, Orth A, Chanda SK, Batalov S and Joazeiro CA (2008) Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle’s dynamics and signaling. PLoS 3 e1487
Li W, He H, Kawakita T, Espana EM and Tseng SC (2005) Amniotic membrane induces apoptosis of interferon-gamma activated macrophages in vitro. Experimental Eye Research 82 282-292
Li W, Maeda N and Beck MA (2006) Vitamin C deficiency increases the lung pathology of influenza virus-infected gulo-/- mice. Journal of Nutrition 136 2611-2616
Li W, Wang T, Ma C, Xiong T, Zhu Y and Wang X (2006) Calcitonin gene-related peptide inhibits interleukin-1beta-induced endogenous monocyte chemoattractant protein-1 secretion in type II alveolar epithelial cells. American Journal of Physiology: Cellular Physiology 291 C4456-C465
Li W, Wang YL, Kang LH and Wang GJ (2005) Up-regulation of costimulatory molecules by sodium butyrate in acute leukemia cells and its molecular mechanism [Article in Chinese]. Zhonghua Xue Ye Xue Za Zhi 26 265-268
Li W, Zheng T, Wang J, Altura BT and Altura BM (1999) Pyrrolidine dithiocarbamate prevents ethanol-induced elevation of [Ca2+]i in cultured canine cerebral vascular smooth muscle cells. Neuroscience Letters 266 205-208
Li WD, Dong YJ, Tu YY and Lin ZB (2006) Dihydroarteannuin ameliorates lupus symptom of BXSB mice by inhibiting production of TNF-a and blocking the signaling pathway NF-kB translocation. International Immunopharmacology 6 1243-1250
Li WG, Gavrila D, Liu X, Wang L, Gunnlaugsson S, Stoll LL, McCormick ML, Sigmund CD, Tang C and Weintraub NL (2004) Ghrelin inhibits proinflammatory responses and nuclear factor-kB activation in human endothelial cells. Circulation 109 2221-2226
Li WM, Liu W, Gao C, Zhou BG, Yang SS, Wang Z, Zhang RH, Gan RT, Kong YH and Li Y (2006) Antigen-specific tolerance induced by IL-10 gene modified immature dendritic cells in experimental autoimmune myocarditis in rats. Chinese Medical Journal (English) 119 1646-1652
Li X (2008) IRAK4 in TLR/IL-1R signaling: possible clinical applications. European Journal of Immunology 38 614-618
Li X, Bradford BU, Dalldorf F, Goyert SM, Stimpson SA, Thurman RG and Makarov SS (2004) CD14 mediates the innate immune responses to arthritopathogenic peptidoglycan-polysaccharide complexes of Gram-positive bacterial cell walls. Arthritis Research Therapy 6 R273-R281
Li X, Bradford BU, Wheeler MD, Stimpson SA, Pink HM, Brodie TA, Schwab JH and Thurman RG (2001) Dietary glycine prevents peptidoglycan polysaccharide-induced reactive arthritis in the rat: role for glycine-gated chloride channel. Infection and Immunity 69 5883-5891
Li X, Chen D, Yin S, Meng Y, Yang H, Landis-piwowar KR, Li Y, Sarkar FH, Reddy GP, Dou QP and SHeng S (20007) Maspin augments proteasome inhibitor-induced apoptosis in prostate cancer cells. Journal of Cellular Physiolgoy in press
Li X, Commane M, Jiang Z and Stark GR (2001) IL-1-induced NFkB and c-Jun N-terminal kinase (JNK) activation diverge at IL-1 receptor-associated kinase (IRAK). Proceedings of the National Academy of Sciences USA 98 4461-4465
Li X, Commane M, Nie H, Hua X, Chatterjee-Kishore M, Wald D, Haag M and Stark GR (2000) Act1, an NF-kB-activating protein. Proceedings of the National Academy of Sciences USA 97 10489-10493
Li X, Du JR, Wang WD, ZHeng XY, Sun W, Zong X, Sheng H and Qian ZM (2006) Experimental study of effect of tanshinone on artery restenosis in rat carotid injury model [Article in Chinese]. Zhongguo Zhong Yao Za Zhi 31 580-584
Li X, Fang Y, Zhao X, Jiang X, Duong T and Kain SR (1999) Characterization of NFkB activation by detection of green fluorescent protein-tagged IkappaB degradation in living cells. Journal of Biological Chemistry 274 21244-21250
Li X, Hua L, Deng F, Bai X, Zeng W, Lu D, Su Y and Luo S (2005) NF-kB and Hsp70 are involved in the phospholipase Cgamma1 signaling pathway in colorectal cancer cells. Life Sciences 77 2794-2803
Li X, Kiumura H, Hirota K, Kasuno K, Torii K, Okada T, Kurooka H, Yokota Y and Yoshida H (2005) Synergistic effect of hypoxia and TNF-alpha on production of PAI-1 in human proximal renal tubular cells. Kidney International 68 569-583
Li X, Lei T, Xia T, Chen X, Feng S, Chen H, Chen Z, Peng Y and Yang Z (2008) Molecular characterization, chromosomal and expression patterns of three aquaglyceroporins (AQP3, 7, 9) from pig. Comparative Biochemistry and Physiology B Biochemistry and Molecular Biology in press
Li X and Liao WS-L (1991) Expression of rat serum amyloid A1 gene involves both C/EBP-like and NF-kB-like transcription factors. Journal of Biological Chemistry 266 15192-15201
Li X and Liao WSL (1992) Cooperative effects of C/EBP-like and NFkB-like binding sites on rat serum amyloid A1 gene expression in liver cells. Nucleic Acids Research 20 4765-4772
Li X and Makarov SS (2006) An essential role of NF-kB in the “tumor-like” phenotype of arthritic synoviocytes. Proceedings of the Natlional Academy of Sciences USA in press
Li X, Massa PE, Hanidu A, Peet GW, Aro P, Savitt A, Mische S, Li J and Marcu KB (2002) IKKa, IKKb and NEMO/IKKg are each required for the NF-kB mediated inflammatory response program. Journal of Biological Chemistry 277 45129-45140
Li X, Meng Y, Chen Q, Yang XS, Zhou GS and Wu PS (2005) Effect of Angiotensin II on NF-kB activity and expression of PDGF-BB, TGF beta 1 and COX-2 in Kupffer’s cells [Article in Chinese]. Zhonghua Gan Zang Bing Za Zhi 13 150-151
Li X, Meng Y, Jiang B, Yang XS, Wang WW, Guo D, Lai ZS and Zhang ZS (2005) Effects of angiotensin II and aldosterone on NF-kB binding activity in hepatic stellate cells [Article in Chinese]. Zhonghua Yi Xue Za Zhi 374-380
Li X, Meng Y, Wu P, Zhang Z and Yang X (2006) Angiotensin II and Aldosterone stimulating NF-kB and AP-1 activation in hepatic fibrosis of rat. RegulatoryPeptides in press
Li X, Meng Y, Yang XS, Mi LF and Cai SX (2005) ACEI attenuates the progression of CCl(4)-induced rat hepatic fibrogenesis by inhibiting TGF-beta1, PDGF-BB, NF-kB and MMP-2,9. World Journal of Gastroenterology 11 4807-4811
Li X and Minden A (2005) Pak4 functions in TNFa induced survival pathways by facilitating TRADD binding to the TNF receptor. Journal of Biological Chemistry 280 41192-41200
Li X, Tupper JC, Bannerman DD, Winn RK, Rhodes CJ and Harlan JM (2003) Phosphoinositide 3 kinase mediates Toll-like receptor 4-induced activation of NF-kB in endothelial cells. Infection & Immunity 71 4414-4420
Li X, Wang H, Touma E, Qi Y, Rousseau E, Quigg RJ and Ryaby JT (2007) TP508 accelerates fracture repair by promoting cell growth over cell death.Biochemical and Biophysical Research Communications in press
Li X, Wen Z, He X and He S (2006) Effects of cinnamic acid on expression of tissue factor induced by TNFa in endothelial cells and its mechanisms. Journal of Chinese Medical Association 69 207-212
Li X, Yang Y and Ashwell JD (2002) TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2. Nature 416 345-347
Li X, Xing D, Wang J, Zhu DB, Zhang L, Chen XJ, Sun Fy and Hong A (2006) Effects of IkBa and its mutants on NF-kB and p53 signaling pathways. World Journal ofGastroenterology 12 6658-6664
Li X, Zhang R, Luo D, Park SJ, Wang Q, Kim Y and Min W (2005) TNF-induced desumoylation and cytoplasmic translocation of HIPK1 are critical for ASK1-JNK/p38 activation. Journal of Biological Chemistry 280 15061-15070
Li XC, Ma YF and Wang XH (2006) Role of NF-kB as effector of IPC in donor livers before liver transplantation in rats. Transplantation Proceedings 38 1584-1587
Li XC and Zhuo JL (2008) Nuclear factor-kB as a hormonal intracellular signaling molecule: focus on angiotensin II-induced cardiovascular and renal injury. Current Opinion in Nephrology and Hypertension in press
Li XD, Sun L, Seth RB, Pineda G and Chen ZJ (2005) Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity. Proceedings of the National Academy of Sciences USA 102 17717-17722
Li XH and Gaynor RB (1999) Regulation of NF-kB by the HTLV-1 Tax protein. Gene Expression 7 233-245
Li XH, Murphy KM, Palka KT, Surabhi RM and Gaynor RB (1999) The human T-cell leukemia virus type-1 Tax protein regulates the activity of the IkappaB kinase complex. Journal of Biological Chemistry 274 34417-34424
Liu XM, Jia Z, Zhou ZQ and Xu JG (2007) Cardioprotection of recombinant human erythropoietin pretreatment on ischemia-reperfused hearts and mechanism thereof: experiment with rats [Article in Chinese]. Zhonghua Yi Xue Za Zhi 87 2463-2467
Li XZ, Zhou Y, Liu CF and Bai LM (2007) A dual effect on the growth of astrocytes of lipopolysaccharide [Article in Chinese]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 23 934-936
Li Y, Ahmed F, ALi S, Philip PA, Kucuk O and Sarkar FH (2005) Inactivation of nuclear factor kB by soy isoflavone genistein contributes to increased apoptosis induced by chemotherapeutic agents in human cancer cells. Cancer Research 65 6934-6942
Li Y, Chinni SR and Sarkar FH (2005) Selective growth regulatory and pro-apoptotic effects of DIM is mediated by AKT and NF-kB pathways in prostate cancer cells. Frontiers in Bioscience 10 236-243
Li Y, Chu N, Hu A, Gran B, Rostmi A and Zhang GX (2007) Inducible IL-23p19 expression in human microglia via p38 MAPK and NF-kB signal pathways. Experimental and Molecular Pathology in press
Li Y, Gerbod-Giannone MC, Seitz H, Cui D, Thorp E, Tall AR, Matsushima GK and Tabas I (2005) Cholesterol-induced apoptotic macrophages elicit an inflammatory response in phagocytes that is partially attenuated by the Mer receptor. Journal of Biological Chemistry in press
Li Y, Limmon GV, Imani F and Teng C (2008) Induction of lactoferrin gene expression by innate immune stimuli in mouse mammary epithelial HC-11 cells. Biochimie in press
Li Y and Rinehart CA (1998) Regulation of keratinocyte growth factor expression in human endometrium: implications for hormonal carcinogenesis. Molecular Carcinogenesis 23 217-225
Li Y and Sarkar FH (2002) Inhibition of nuclear factor kB activation in PC3 cells by genistein is mediated via Akt signaling pathway. Clinical Cancer Research 8 2369-2377
Li Y, Barger SW, Liu L, Mrak RE and Griffin WS (2000) S100beta induction of the proinflammatory cytokine interleukin-6 in neurons. Journal of Neurochemistry 74 143-150
Li Y, Chi L, Stechschulte DJ and Dileepan KN (2001) Histamine-induced production of interleukin-6 and interleukin-8 by human coronary artery endothelial cells is enhanced by endotoxin and tumor necrosis factor-alpha. Microvascular Research 61 253-262
Li Y, Ellis KL, Ali S, El-Rayes BF, Nedeljkovic-Kurepa A, Kucuk O, Philip PA and Sarkar FH (2004) Apoptosis-inducing effect of chemotherapeutic agents is potentiated by soy isoflavone genistein, a natural inhibitor of NF-kB in BxPC-3 pancreatic cancer cell line. Pancreas 28 E90-E95
Li Y, Gazdoiu S, Pan ZQ and Fuchs SY (2004) Stability of homologue of slimb F-box protein is regulated by availability of its substrate. Journal of Biological Chemistry 279 11074-11080
Li Y, Glauert HP and Spear BT (2000) Activation of nuclear factor-kB by the peroxisome proliferator ciprofibrate in H4IIEC3 rat hepatoma cells and its inhibition by the antioxidants N-acetylcysteine and vitamin E. Biochemical Pharmacology 59 427-434
Li Y, He B and Wang H (1999) [The effect of erythromycin on NF-kB activation and cytokines mRNA expression in bleomycin-induced pulmonary fibrosis in rats] [Article in Chinese]. Zhonghua Jie He He Hu Xi Za Zhi 22 725-772
Li Y, Ha T, Gao X, Kelley J, Williams DL, Browder IW, Kao RL and Li C (2004) NFkB activation is required for the development of cardiac hypertrophy in vivo. American Journal of Physiology: Heart and Circulatory Physiology 287 H1712-H1720
Li Y, Hu J, Vita R, Sun B, Tabata H and Altman A (2004) SPAK kinase is a substrate and target of PKCtheta in T-cell receptor-induced AP-1 activation pathway. EMBO Journal 23 1112-1122
Li Y, Jiang C, Xu G, Wang N, Xhu Y, Tang C and Wang X (2008) Homocysteine upregulates resistin production from adipocytes in vivo and in vitro. Diabetes in press
Li Y, Kang J, Friedman J, Tarassishin L, Ye J, Kovalenko A, Wallach D and Horwitz MS (1999) Identification of a cell protein (FIP-3) as a modulator of NF-kB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis. Proceedings of the National Academy of Sciences USA 96 1042-1047
Li Y, Kim IC, Kim YJ, Kim MK, Yoon YD, Lee YS and Lee JS (2004) Cloning and sequence analysis of the self-fertilizing fish Rivulus marmoratus immediate early gene c-fos. Marine Environmental Research 58 681-685
Li Y, Kucuk O, Hussain M, Abrams J, Cher ML and Sarkar FH (2006) Antitumor and antimetastatic activities of docetaxel are Eenhanced by genistein through regulation of osteoprotegerin/receptor activator of nuclear factor-kB (RANK)/RANK ligand/MMP-9 signaling in prostate cancer. Cancer Research 664816-4825
Li Y, Leung LK, Spear BT and Glauert HP (1996) Activation of hepatic NF-kB by phenobarbital in rats. Biochemical and Biophysical Research Communications 229 982-989
Li Y, Li A, Strait K, Zhang H, Nanes MS and Weitzmann MN (2007) Endogenous TNFalpha lowers maximum peak bone mass and inhibits osteoblastic Smad activation, through NF-kB. Journal of Bone and Mineral Research in press
Li Y, Li G, Ivanova A, Aaron S and Simm M (2008) The critical role of human transcriptional repressor CTCF mRNA up-regulation in the induction of anti-HIV-1 responses in CD4(+) T cells. Immunology Letters in press
Li Y, Li G, Li C and Zhao Y (2007) Identification of nuclear factor-kB responsive element within the neuronal nitric oxide synthase exon 1f-specific promoter. Acta Biochimica et Biophysica Sinica (Shanghai) 39 247-254
Li Y, Li X and Sarkar FH (2003) Gene expression profiles of I3C- and DIM-treated PC3 human prostate cancer cells determined by cDNA microarray analysis. Journal of Nutrition 133 1011-1019
Li Y, Li Y and Liu GT (2004) Protective effects of bicyclol on liver fibrosis induced by carbon tetrachloride [Article in Chinese]. Zhonghua Yi Xue Za Zhi 84 2096-2101
Li Y, Liu W, Xing G, Tian C, Zhu Y and He F (2005) Direct association of hepatopoietin with thioredoxin constitutes a redox signal transduction in activation of AP-1/NF-kB. Cell Signal 17 985-996
Li Y, Mak G and Franza Jr BR (1994) In vitro study of functional involvement of Sp1, NF-kB/Rel, and AP1 in phorbol 12-myristate 13-acetate-mediated HIV-1 long terminal repeat activation. Journal of Biological Chemistry 269 30616-30619
Li Y and Sarkar FH (2002) Gene expression profiles of genistein-treated PC3 prostate cancer cells. Journal of Nutrition 132 3623-3631
Li Y, Schwabe RF, Devries-Seimon T, Yao PM, Gerbod-Giannone MC, Tall AR, Davis RJ, Flavell R, Brenner DA and Tabas I (2005) Free cholesterol-loaded macrophages are an abundant source of TNF-a and IL-6. Model of NF-kB- and MAP kinase-dependent inflammation in advanced atherosclerosis. Journal of Biological Chemistry 280 21763-21772
Li Y, Sedwick CE, Hu J and Altman A (2005) Role for PKCtheta in TCR/CD28-mediated signaling through the canonical but not the non-canonical pathway for NF-kB activation. Journal of Biological Chemistry 280 1217-1223
Li Y, Tharappel JC, Cooper S, Glenn M, Glauert HP and Spear BT (2002) Expression of the hydrogen peroxide-generating enzyme fatty acyl CoA oxidase activates NF-kB. DNA Cell Biology 19 113-120
Li Y, Toraldo G, Li A, Yang X, Zhang H, Qian WP and Weitzmann MN (2007) B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo. Blood in press
Li Y, Yuan Z, Liu B, Sailhamer EA, Shults C, Velmahos GC, Demoya M and Alam HB (2008) Prevention of hypoxia-induced neuronal apoptosis through histone deacetylase inhibition. Journal of Trauma 64 863-870
Li Y, Zhang T, Douglas SD, Lai JP, Xiao WD, Pleasure DE and Ho WZ (2003) Morphine enhances hepatitis C virus (HCV) replicon expression. American Journal of Pathology 163 1167-1175
Li Y, Zhang X, Zhu B and Xue Z (2008) Desflurane preconditioning inhibits endothelial nuclear factor-kB activation by targeting the proximal end of tumor necrosis factor-a signaling. Anesthesia and Ahalgesia 106 1473-1479
Li Y, Zhang Z, Xu Y, Xiong S, Ni W and Chen S (2006) TNF-alpha up-regulates matrix metalloproteinase-9 expression and activity in alveolar macrophages from patients with chronic obstructive pulmonary disease. Journla of Huazhong University Science and Technology Medical Sciences 26 647-650
Li Y, Zhao Y, Li G, Wang J, Li T, Li W and Lu J (2007) Regulation of neuronal nitric oxide synthase exon 1f gene expression by nuclear factor-kappaB acetylation in human neuroblastoma cells. Journal of Neurochemistry in press
Li YC, Kong LH and Li KS (2006) Inducement effect of recombinant human TNF-a on apoptosis of breast cancer cell line ZR75-1 and its mechanism [Article in Chinese]. Ai Zheng 25 560-565
Li YG, Iwabu Y, Warachit J, Kinomoto M, Ibrahim MS, Tsuji S, Mukai T, Kameoka M, Tokunaga K, Sata T and Ikuta K (2005) Interleukin-4 up-regulates T-tropic Human Immunodeficiency Virus type 1 transcription in primary CD4(+) CD38(+) T-lymphocyte subset. Microbiol Immunol 49 155-165
Li YH, Ha TZ, Chen Q and Li CF (2005) Role of MyD88-dependent nuclear factor-kappaB signaling pathway in the development of cardiac hypertrophy in vivo [Article in Chinese]. Zhonghua Yi Xue Za Zhi 85 267-272
Li YH, Huang ZW, Xue P, Guo J, He FQ, You Z and Wang ZR (2008) Effects of Chaiqin Chengqi Decoction on activation of nuclear factor-kB in pancreas of rats with acute necrotizing pancreatitis [Article in Chinese]. Zhong Xi Yi Jie He Xue Bao 6 180-184
Li YH, Yan ZQ, Brauner A and Tullus K (2001) Meconium induces expression of inducible NO synthase and activation of NF-kB in rat alveolar macrophages. Pediatrics Research 49 820-825
Li YH, Yan ZQ, Brauner A and Tullus K (2002) Activation of macrophage nuclear factor-kB and induction of inducible nitric oxide synthase by LPS. Respiration Research 3 23
Li YH, Yan ZQ, Jensen JS, Tullus K and Brauner A (2000) Activation of nuclear factor kB and induction of inducible nitric oxide synthase by Ureaplasma urealyticum in macrophages. Infection and Immunity 68 7087-7093
Li YP, Handberg KJ, Juul-Madsen HR, Zhang MF and Jorgensen PH (2007) Transcriptional profiles of chicken embryo cell cultures following infection with infectious bursal disease virus. Archives of Virology in press
Li YP, Lecker SH, Chen Y, Waddell ID, Goldberg AL and Reid MB (2003) TNF-alpha increases ubiquitin-conjugating activity in skeletal muscle by up-regulating UbcH2/E220k. FASEB Journal 17 1048-1057
Li YP and Schwartz RJ (2001) TNF-a regulates early differentiation of C2C12 myoblasts in an autocrine fashion. FASEB Journal 15 1413-1415
Li YQ, Zhang ZX, Xu YJ, Ni W, Chen SX, Yang Z and Ma D (2006) N-Acetyl-L-cysteine and pyrrolidine dithiocarbamate inhibited nuclear factor-kB activation in alveolar macrophages by different mechanisms. Acta Pharmacologica Sinica 27 339-346
Li YQ, Zhang ZX, Xu YJ, Xiong SD, Yang Z, Ni W, Chen SX and Ma D (2006) Tumor necrosis factor alpha-induced expression and activity of alveolar macrophages matrix metalloproteinase-9 in chronic obstructive pulmonary disease [Article in Chinese]. Zhonghua Nei Ke Za Zhi 45 38-41
Li YT, Sales KE, Thomas GJ, Warner TD and Bishop-Bailey D (2007) Farnesoid x receptor ligands inhibit vascular smooth muscle cell inflammation and migration. Arteriosclerosis, Thrombosis, and Vascular Biology in press
Li YW, Jin HL, Wang BG, Shi ZH and Li J (2007) Toll-like receptor 4 signal pathway may be involved in cerebral ischemic tolerance induced by hypoxic preconditioning: experiment with rats [Article in Chinese]. Zhanghua Y, Xue Za Zhi 87 2458-2462
Li Z, Chen Y, Cao D, Wang Y, Chen G, Zhang S and Lu J (2006) Glucocorticoid upregulates transforming growth factor-beta type II receptor and enhances TGF-beta signaling in human prostate cancer PC-3 cells. Endocrinology in press
Li Z, Huang Y and Yang Z (2002) The influence of burn sera on the nuclear translocation of endothelial NF-kB p50 and p65 [Article in Chinese]. Zhonghua Shao Shang Za Zhi 18 265-267
Li Z, Jansen M, Ogburn K, Salvatierra L, Hunter L, Mathew S and Figueiredo-Pereira ME (2004) Neurotoxic prostaglandin J2 enhances cyclooxygenase-2 expression in neuronal cells through the p38MAPK pathway: A death wish? Journal of Neuroscience Research 78 824-836
Li Z and Nabel GJ (1997) A new member of the IkB protein family, IkBe, inhibits RelA(p65)-mediated NF-kB transcription. Molecular and Cellular Biology 17 6184-6190
Li Z, Niu J, Uwagawa T, Peng B and Chiao PJ (2005) Function of polo-like kinase 3 in NF-kB-mediated proapoptotic response. Journal of Biological Chemistry 280 16843-16850
Li Z, Wang X, Yu RY, Ding BB, Yu JJ, Dai XM, Naganuma A, Stanley ER and Ye BH (2005) BCL-6 negatively regulates expression of the NF-kB1 p105/p50 subunit. Journal of Immunology 174 205-214
Li Z, Yang S, Lin H, Huang J, Watkins PA, Moser AB, Desimone C, Song XY and Diehl AM (2003) Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease. Hepatology 37 343-350
Li Z, Zhang J, Chen D and Shu HB (2003) Casper/c-FLIP is physically and functionally associated with NF-kB1 p105. Biochemical and Biophysical Research Communications 309 980-985
Li ZG, Zhang W and Sima AA (2003) C-peptide enhances insulin-mediated cell growth and protection against high glucose-induced apoptosis in SH-SY5Y cells. Diabetes Metab Res Rev 19 375-385
Li ZQ, Huang YS, Yang ZC and Wang JH (2005)
Effects of burn patients’ serum on IkBa degradation and NF-kB activation in endothelial cells in vitro [Article in Chinese]. Di Yi Jun Yi Da Xue Xue Bao 25 181-183
Li ZQ, Huang YS, Yang ZC and Wang JH (2005) Effect of burn serum on the nuclear translocation of monocytic NF-kB p50/p65 [Article in Chinese]. Zhonghua Shao Shang Za Zhi 20 265-267
Li ZM, Ma JF and Wang LN (2007) Influence of atorvastatin on the expression of monocyte chemoattractant protein-1 in peritoneal mesothelial cells by high glucose [Article in Chinese]. Zhonghua Yi Xue Za Shi 87 2677-2680
Li ZW, Chen H, Campbell RA, Bonavida B and Berenson JR (2008) NF-kB in the pathogenesis and treatment of multiple myeloma. Current Opinion in Hematology 15 391-399
Li ZW, Chu W, Hu Y, Delhase M, Deerinck T, Ellisman M, Johnson R and Karin M (1999) The IKKb subunit of IkB kinase (IKK) is essential for nuclear factor kB activation and prevention of apoptosis. Journal of Experimental Medicine 189 1839-1845
Li ZQ, Huang YS, Yang ZC and Wang JH (2005) Influence of nuclear factor-kB activation on the expression of cytokines in monocytes stimulated by burn serum [Article in Chinese]. Zhonghua Shao Shang Za Zhi 21 434-437
Li ZQ, Huang YS, Yang ZC and Wang JH (2006) The role of nuclear factor-kB in the burn serum-induced expression of intercellular adhesion molecules-1 in endothelial cells [Article in Chinese]. Zhonghua Shao Shang Za Zhi 22 366-368
Li ZQ, Huang YS, Yang ZC and Wang JH (2007) Effect of NF-kappaB activation on the early expression of tumor necrosis factor alpha and myocardial dysfunction in burned rats [Article in Chinese]. Zhonghua Shao Shang Za Zhi 22 448-451
Li ZQ, Huang YS, Yang ZC and Wang JH (2007) Effect of nuclear factor-kB activation on expression of proinflammatory cytokines in rat lung tissues in early stage of burn injury [Article in Chinese]. Nan Fang Yi Ke Da Xue Xue Bao27 1496-1497
Li ZW, Chen H, Campbell RA, Bonavida B and Berenson JR (2008) NF-kB in the pathogenesis and treatment of multiple myeloma. Current Opinions in Hematology 15 391-399
Li ZW, Omori SA, Labuda T, Karin M and Rickert RC (2003) IKKbeta is required for peripheral B cell survival and proliferation. Journal of Immunology 170 4630-4637
Li ZW, Rickert RC and Karin M (2004) Genetic dissection of antigen receptor induced-NF-kB activation. Molecular Immunology 41 701-714
Liacini A, Sylvester J, Li WQ and Zafarullah M (2002) Inhibition of interleukin-1-stimulated MAP kinases, activating protein- 1 (AP-1) and nuclear factor kappa B (NF-kB) transcription factors down-regulates matrix metalloproteinase gene expression in articular chondrocytes. Matrix Biology 21 251-262
Liacini A, Sylvester J, Qing Li W, Huang W, Dehnade F, Ahmad M and Zafarullah M (2003) Induction of matrix metalloproteinase-13 gene expression by TNF-alpha is mediated by MAP kinases, AP-1, and NF-kB transcription factors in articular chondrocytes. Experimental Cell Research 288 208-217
Liagre B, Bertrand J, Leger DY and Beneytout JL (2005) Diosgenin, a plant steroid, induces apoptosis in COX-2 deficient K562 cells with activation of the p38 MAP kinase signalling and inhibition of NF-kB binding. International Journal of Molecular Medicine 16 1095-1101
Liagre B, Leger DY, Vergne-Salle P and Beneytout JL (2007) MAP kinase subtypes and Akt regulate diosgenin-induced apoptosis of rheumatoid synovial cells in association with COX-2 expression and prostanoid production. InternationalJournal of Molecular Medicine 19 113-122
Liakopoulos OJ, Dorge H, Schmitto JD, Nagorsnik U, Grabedunkel J and Schoendube FA (2006) Effects of preoperative statin therapy on cytokines after cardiac surgery. Thoracic and Cardiovascular Surgery 54 250-254
Lian Z, Liu J, Pan J, Satiroglu Tufan NL, Zhu M, Arbuthnot P, Kew M, Clayton MM and Feitelson MA (2001) A cellular gene up-regulated by hepatitis B virus-encoded X antigen promotes hepatocellular growth and survival. Hepatology 34 146-157
Liang C, Zhang M and Sun SC (2006) beta-TrCP binding and processing of NF-kB2/p100 involve its phosphorylation at serines 866 and 870. Cell Signaling 18 1309-1317
Liang F and Gardner DG (1999) Mechanical strain activates BNP gene transcription through a p38/NF-kB-dependent mechanism. Journal of Clinical Investigation 104 1603-1612
Liang F, Hu DY, Wang BY, Huang N, Wu Q and Chen HQ (2005) Transcriptional activation of interleukin-8 gene induced by shear stress in human umbilical vein endothelial cells [Article in Chinese]. Zhonghua Nei Ke Za Zhi 44 421-424
Liang F, Huang N, Wang B, Chen H and Wu L (2002) Shear stress induces interleukin-8 mRNA expression and transcriptional activation in human vascular endothelial cells. Chinese Medical Journal (English) 115 1838-1842
Liang H, Baudouin C, Behar-Cohen F, Crisanti P and Omri B (2007) Protein kinase C-zeta mediates retinal degeneration in response to TNF. Journal ofNeuroimmunology 183 104-110
Liang HL and Ouyang Q (2006) A clinical trial of rosiglitazone and 5-aminosalicylate combination for ulcerative colitis [Article in Chinese].Zhonghua Nei Ke Za Zhi 45 548-551
Liang KC, Lee CW, Lin WN, Lin CC, Wu CB, Luo SF and Yang CM (2007) Interleukin-1b induces MMP-9 expression via p42/p44 MAPK, p38 MAPK, JNK, and nuclear factor-kB signaling pathways in human tracheal smooth muscle cells. Journal of CellularPhysiology in press
Liang M-C, Bardhan S, Li C, Pace EA, Porco JA Jr and Gilmore TD (2003) Jesterone dimer, a synthetic derivative of the fungal metabolite jesterone, bocks activation of transcription factor nuclear factor kB by inhibiting the Inhibitor of kB Kinase. Molecular Pharmacology 64 123-131
Liang M-C, Bardhan S, Pace EA, Rosmann D, Beutler JA, Porco Jr JA and Gilmore TD (2006) Inhibition of transcription factor NF-kB signaling proteins IKKb and p65 through specific cysteine resdiues by epoxyquinone A monomer: correlation with its anti-cancer cell growth activity. Biochemical Pharmacology 71 634-645
Liang M-C, Bardhan S, Porco Jr JA and Gilmore TD (2006) The synthetic exposyquinoids jesterone dimer and epoxyquinone A monomer induce apoptosis and inhibit REL (human c-Rel) DNA binding in an IkBa-deficient diffuse large B-cell lymphoma cell line. Cancer Letters 241 69-78
Liang MH and Chuang DM (2006) Differential roles of glycogen synthase kinase-3 isoforms in the regulation of transcriptional activation. Journal of BiologicalChemistry in press
Liang Q, Smith AD, Pan S, Tyurin VA, Kagan VE, Hastings TG and Schor NF (2005) Neuroprotective effects of TEMPOL in central and peripheral nervous system models of Parkinson’s disease. Biochemical Pharmacology 70 1371-1381
Liang S, Wang M, Triantafilou K, Triantafilou M, Nawar HF, Russell MW, Connell TD and Hajishengallis G (2007) The A subunit of type IIb enterotoxin (LT-IIb) suppresses the proinflammatory potential of the B subunit and its ability to recruit and interact with TLR2. Journal of Immunology 178 4811-4819
Liang S, Wei H, Sun R and Tian Z (2003) IFNalpha regulates NK cell cytotoxicity through STAT1 pathway. Cytokine 23 190-199
Liang S, Zhang J, Wei H, Sun R and Tian Z (2005) Differential roles of constitutively activated ERK1/2 and NF-kB in cytotoxicity and proliferation by human NK cell lines. International Immunopharmacology 5 839-848
Liang SC, Latchman YE, Buhlmann JE, Tomczak MF, Horwitz BH, Freeman GJ and Sharpe AH (2003) Regulation of PD-1, PD-L1, and PD-L2 expression during normal and autoimmune responses. European Journal of Immunology 33 2706-2716
Liang TB, Man K, Kin-Wah Lee T, Hong-Teng Tsui S, Lo CM, Xu X, Zheng SS, Fan ST, Wong J (2003) Distinct intragraft response pattern in relation to graft size in liver transplantation. Transplantation 75 673-678
Liang X and Ji Y (2007) Involvement of alpha5beta1-integrin and TNF-a in Staphylococcus aureusalpha-toxin-induced death of epithelial cells. CellularMicrobiology in press
Liang Y, Zhou Y and Shen PP (2004) NF-kB and its regulation on the immune system. Cell and Molecular Immunology 1 343-350
Liang YC, Huang YT, Tsai SH, Lin-Shiau SY, Chen CF and Lin JK (1999) Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages. Carcinogenesis 20 1945-1952
Liang YJ, Lai LP, Wang BW, Juang SJ, Chang CM, Leu JG and Shyu KG (2006) Mechanical stress enhances serotonin 2B receptor modulating brain natriuretic peptide through nuclear factor-kB in cardiomyocytes. Cardiovascular Research 72 303-312
Liang YJ, Shyu KG, Wang BW and Lai LP (2006) C-reactive protein activates the nuclear factor-kB pathway and induces vascular cell adhesion molecule-1 expression through CD32 in human umbilical vein endothelial cells and aortic endothelial cells. Journal of Molecular and Cellular Cardiology 40 412-420
Liang YJ, Shyu KG, Wang BW and Lai LP (2007) Simvastatin inhibits C-reactive protein-induced pro-inflammatory changes in endothelial cells by decreasing mevalonate pathway products. Cardiology 110 182-190
Liang ZQ, Li YL, Zhao XL, Han R, Wang XX, Wang Y, Chase TN, Bennett MC and Qin ZH (2007) NF-kB contributes to 6-hydroxydopamine-induced apoptosis of nigral dopaminergic neurons through p53. Brain Research 1145 190-203
Liang ZQ, Wang X, Li LY, Wang Y, Chen RW, Chuang DM, Chase TN and Qin ZH (2007) Nuclear factor-kappaB-dependent cyclin D1 induction and DNA replication associated with N-methyl-D-aspartate receptor-mediated apoptosis in rat striatum. Journal of Neuroscience Research in press
Lianxu C, Hongti J and Changlong Y (2005) NF-kBp65-specific siRNA inhibits expression of genes of COX-2, NOS-2 and MMP-9 in rat IL-1b-induced and TNF-a-induced chondrocytes. Osteoarthritis and Cartilage 14 367-376
Liao BC, Hsieh CW, Liu YC, Tzeng TT, Sun YW and Wung BS (2008) Cinnamaldehyde inhibits the tumor necrosis factor-a-induced expression of cell adhesion molecules in endothelial cells by suppressing NF-kB activation: effects upon IkB and Nrf2. Toxicology and Applied Pharmacology in press
Liao CH, Sang S, Liang YC, Ho CT and Lin JK (2004) Suppression of inducible nitric oxide synthase and cyclooxygenase-2 in downregulating nuclear factor-kB pathway by Garcinol. Molecular Carcinogenesis 41 140-149
Liao CL, Lin YL, Wu BC, Tsao CH, Wang MC, Liu CI, Huang YL, Chen JH, Wang JP and Chen LK (2001) Salicylates inhibit flavivirus replication independently of blocking nuclear factor kB activation. Journal of Virology 75 7828-7839
Liao C, Thakur A, Wu J, Biliran H and Sakar FH (2007) Perspectives on c-Myc, Cyclin D1, and their interaction in cancer formation, progression, and response to chemotherapy. Critical Reviews in Oncogenesis 13 93-158
Liao G and Sun SC (2003) Regulation of NF-kB2/p100 processing by its nuclear shuttling. Oncogene 22 4868-4874
Liao G, Zhang M, Harhaj EW and Sun SC (2004) Regulation of the NF-kB inducing kinase by TRAF3-induced degradation. Journal of Biological Chemistry 279 26243-26250
Liao HF, Kuo CD, Yang YC, Lin CP, Tai HC, Chen YY and Chen YJ (2005) Resveratrol enhances radiosensitivity of human non-small cell lung cancer NCI-H838 cells accompanied by inhibition of nuclear factor-kB activation. Journal of Radiation Research (Tokyo) 46 387-393
Liao HJ, de Los Santos J and Carpenter G (2006) Contrasting role of phospholipase C-gamma1 in the expression of immediate early genes induced by epidermal or platelet-derived growth factors. Experimental Cell Research 312 807-816
Liao JK, Liao HM and Luo XH (2003) Change of nuclear factor-kB activity in ear
ly burn injury and its significance. [Article in Chinese]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 15 220-221
Liao RX, Sun JG, Zhong XL, Zhou JX and Wang YZ (2006) Experimental study on transcription regulation of mouse hepcidin gene by NF-kB [Article in Chinese].Zhonghua Gan Zang Bing Za Zhi 14 118-123
Liao QJ, Ye LB, Timani KA, She YL, Yang XJ, Ye L and Wu ZH (2005) Hepatitis C virus non-structural 5A protein can enhance full-length core protein-induced nuclear factor-kB activation. World Journal of Gastroenterology 11 6433-6439
Liao QJ, Ye LB, Timani KA, Zeng YC, She YL, Ye L and Wu ZH (2005) Activation of NF-kB by the full-length nucleocapsid protein of the SARS coronavirus. Acta Biochimica et Biophysica Sinica (Shanghai) 37 607-612
Liao S, Bao X, Liu T, Lai S, Li K, Garofalo RP and Casola A (2008) Role of retinoic acid inducible gene-I in human metapneumovirus-induced cellular signalling. Journal of General Virology 89 1978-1986
Liao SL, Chen WY, Raung SL and Chen CJ (2003) Ethanol attenuates ischemic and hypoxic injury in rat brain and cultured neurons. Neuroreport 14 2089-2094
Liao SL, Ou YC, Chen SY, Chiang AN and Chen CJ (2006) Induction of cyclooxygenase-2 expression by manganese in cultured astrocytes. NeurochemistryInternational in press
Liao W and Ning G (2006) Knockdown of apolipoprotein B, an atherogenic apolipoprotein, in HepG2 cells by lentivirus-mediated siRNA. Biochemical andBiophysical Research Communications 344 478-483
Liao W, Xiao Q, Tchikov V, Fujita KI, Tang W, Wincovitch S, Garfield S, Conze D, El-Deiry WS, Schutze S and Srinivasula SM (2008) CARP-2 is an endosome-associated ubiquitin ligase for RIP and regulates TNF-induced NF-kB activation. Current Biology in press
Liao WT, Chang KL, Yu CL, Chen GS, Chang LW and Yu HS (2004) Arsenic induces human keratinocyte apoptosis by the FAS/FAS ligand pathway, which correlates with alterations in nuclear factor-kB and activator protein-1 activity. Journal of Investigative Dermatology 122 125-129
Liao X, Zhang L, Thrasher JB, Du J and Li B (2003) Glycogen synthase kinase-3b suppression eliminates tumor necrosis factor-related apoptosis-inducing ligand resistance in prostate cancer. Molecular Cancer Therapy 2 1215-1222
Liao XX< Li X, Ma ZF, Wang LC, Du ZM, Dong YG and Ma H (2008) Role of nuclear factor-kB in endothelial injury in acute myocardial infarction [Article in Chinese]. Zongguo Wei ZOng Bing Ji Jiu Yi Xue 20 413-415]
Liao YF, Hung HC, Hsu PC, Kao MC, Hour TC, Tsay GJ and Liu GY (2008) Ornithine decarboxylase interferes with macrophage-like differentiation and matrix metalloproteinase-9 expression by tumor necrosis factor alpha via NF-kB. Leukemia Research in press
Liao ZJ, Ma WL, Meng W, LIang S, Meng FY and Zheng WL (2008) Effect of Velcade on the gene expression profiles of K562 cells: study of its molecular mechanism [Article in Chinese]. Nan Fang Yi Ke Da Xue Xue Bao 28 373-376
Libby EK, Pascal KE, Mordechai E, Adelson ME and Trama JP (2008) Atopobium vaginae triggers an innate immune response in an in vitro model of bacterial vaginosis. Microbes & Infection in press
Liberati NT, Fitzgerald KA, Kim DH, Feinbaum R, Golenbock DT and Ausubel FM (2004) Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response. Proceedings of the National Academy of Sciences USA 101 6593-6598
Liberg D, Lazarevic B, Pero RW and Leanderson T (1999) N-substituted benzamides inhibit NFkB activation and induce apoptosis by separate mechanisms. British Journal of Cancer 81 981-988
Libera LD and Vescovo G (2004) Muscle wastage in chronic heart failure, between apoptosis, catabolism and altered anabolism: a chimaeric view of inflammation? Curr Opin Clin Nutr Metab Care 7 435-441
Libermann TA and D Baltimore (1990) Activation of interleukin-6 gene expression through the NF-kB transcription factor. Molecular and Cellular Biology 10 2327-2334
Libermann TA and Zerbini LF (2006) Targeting transcription factors for cancer gene therapy. Current Gene Therapy 6 17-33
Liboni KC, Li N, Scumpia PO and Neu J (2005) Glutamine modulates LPS-induced IL-8 production through IkB/NF-kB in human fetal and adult intestinal epithelium. Journal of Nutrition 135 245-251
Lich JD, Williams KL, Moore CB, Arthur JC, Davis BK, Taxman DJ and Ting JP (2007) Monarch-1 suppresses non-canonical NF-kB activation and p52-dependent chemokine expression in monocytes. Journal of Immunology 178 1256-1260
Lickteig AJ, Slitt AL, Arkan MC, Karin M and Cherrington NJ (2007) Differential regulation of hepatic transporters in the absence of TNF-a, IL-1b, IL-6 and NF-kB in two models of cholestasis. Drug Metabolism Disposition in press
Lidbury BA and Mahalingam S (2000) Specific ablation of antiviral gene expression in macrophages by antibody-dependent enhancement of Ross River virus infection. Journal of Virology 74 8376-81
Lidbury BA, Rulli NE, Suhrbier A, Smith PN, McColl SR, Cunningham AL, Tarkowski A, van Rooijen N, Fraser RJ and Mahalingam S (2008) Macrophage-derived proinflammatory factors contribute to the development of arthritis and myositis after infection with an arthrogenic alphavirus. Journal of Infectious Disease in press
Liddington RC (2002) A molecular full nelson. Nature 415 373-374
Liden J, Ek A, Palmberg L, Okret S and Larsson K (2003) Organic dust activates NF-kB in lung epithelial cells. Respiratory Medicine 97 882-892
Lieber A, He C-Y, Meuse L, Himeda C, Wilson C and Kay MA (1998) Inhibition of NF-kB activation in combination with Bcl-2 expression allows for persistence of first-generation adenovirus vectors in mouse liver. Journal of Virology 72 9267-9277
Lieberman R (2002) Chemoprevention of prostate cancer: current status and future directions. Cancer Metastasis Reviews 21 297-309
Liedtke C, Plumpe J, Kubicka S, Bradham CA, Manns MP, Brenner DA and Trautwein C (2002) Jun kinase modulates tumor necrosis factor-dependent apoptosis in liver cells. Hepatology 36 315-325
Lievin-Le Moal V, Huet G, Aubert JP, Bara J, Forgue-Lafitte ME, Servin AL and Coconnier MH (2002) Activation of mucin exocytosis and upregulation of MUC genes in polarized human intestinal mucin-secreting cells by the thiol-activated exotoxin listeriolysin O. Cellular Microbiology 4 515-529
Liew FY, Liu H and Xu D (2005) A novel negative regulator for IL-1 receptor and Toll-like receptor 4. Immunology Letters 96 27-31
Liggett SB, Kelly RJ, Paarekh RR, Matkovich SJ, Benner BJ, Hahn HS, Syed FM, Galvez AS, Case KL, McGuire N, Odley AM, Sparks L, Kardia SL and Dorn GW (2007) A functional polymorphism of the Galphaq (GNAQ) gene is associated with accelerated mortality in African American heart failure. Human Molecular Genetics in press
Lil CS, Zhang Q, Lim MK, Sheen DH, Shim SC, Kim JY, Lee SS, Yun KJ, Moon HB, Chung HT and Chae SC (2007) Association of FOXJ1 polymorphisms with systemic lupus erythematosus and rheumatoid arthritis in Korean population. Experimental and Molecular Medicine 39 805-811
Lilienbaum A and Paulin D (1993) Activation of the human vimentin gene by the Tax human T-cell leukemia virus. I. Mechanism of regulation by the NF-kB transcription factor. Journal of Biological Chemistry 268 2180-2188
Lilienbaum A, Duc Dodon M, Alexandre C, Gazzolo L and Paulin D (1990) Effect of human T-cell leukemia virus type I tax protein on activation of the human vimentin gene. Journal of Virology 64 256-263
Lilienbaum A and Israel A (2003) From calcium to NF-kB signaling pathways in neurons. Molecular and Cellular Biology 23 2680-2698
Liljehom S, Hughes K, Grundstrom T and Brodin P (1998) NF-kB only partially mediates Epstein-Barr virus latent membrane protein 1 activation of B cells. Journal of General Virology 79 2117-2125
Liljeroos M, Vuolteenaho R, Morath S, Hartung T, Hallman M and Ojaniemi M (2006) Bruton’s tyrosine kinase together with PI 3-kinase are part of Toll-like receptor 2 multiprotein complex and mediate LTA induced Toll-like receptor 2 responses in macrophages. Cellular Signaling in press
Lille ST, Lefler SR, Mowlavi A, Suchy H, Boyle Jr EM, Farr AL, Su CY, Frank N and Mulligan DC (2001) Inhibition of the initial wave of NF-kB activity in rat muscle reduces ischemia/reperfusion injury. Muscle Nerve 24 534-541
Lilly CM, Tateno H, Oguma T, Israel E and Sonna LA (2004) Effects of allergen challenge on airway epithelial cell gene expression. American Journal of Respiratory Critical Care Medicine 171 579-586
Lim CA, Yao F, Wong JJ, George J, Xu H, Chiu KP, Sung WK, Lipovich L, Vega VB, Chen J, Shahab A, Zhao XD, Hibberd M, Wei CL, Lim B, Ng H, Ruan Y and Chin KC )2007) Genome-wide mapping of RELA(p65) binding identifies E2F1 as a transcriptional activator recruited by NF-kB upon TLR4 activation. MolecularCell 27 622-635
Lim CM, Kim EK, Koh Y, Kim WS, Kim DS and Kim WD (2004) Hypothermia inhibits cytokine release of alveolar macrophage and activation of nuclear factor kB in endotoxemic lung. Intensive Care Medicine 30 1638-1644
Lim EJ, Lee HS, Lee JG, Kim JR, Yun SS, Baek SH and Lee C (2007) Toll-like receptor 9 dependent activation of MAPK and NF-kB is required for the CpG ODN-induced matrix metalloproteinase-9 expression. Experimental and Molecular Medicine 39 239-245
Lim EJ, Smart EJ, Toborek M and Hennig B (2007) The role of caveolin-1 in PCB77-induced eNOS phosphorylation in human-derived endothelial cells. AmericanJournal of Physiology: Heart and Circulatory Physiology in press
Lim H, Lee JG, Lee SH, Kim YS and Kim HP (2008) Anti-inflammatory activity of phylligenin, a lignan from the fruits of Forsythia koreana, and its cellular mechanism of action. Journal of Ethnopharmacology in press
Lim HJ, Lee HS and Ryu JH (2008) Suppression of inducible nitric oxide synthase and cyclooxygenase-2 expression by tussilagone from farfarae flos in BV-2 microglial cells. Archives of Pharmacal Research 31 645-652
Lim JH, Ha U, Sakai A, Woo CH, Kweon SM, Xu H and Li JD (2008) Streptococcus pneumoniae synergizes with nontypeable Haemophilus influenzae to induce inflammation via upregulating TLR2. BMC Immunology in press
Lim JH, Ha UH, Woo CH, Xu H and Li JD (2008) CYLD is a crucial negative regulator of innate immune response in E. coli pneumonia. Cellular Microbiology in press
Lim JH, Jono H, Koga T, Woo CH, Ishinaga H, Bourne P, Xu H, Ha UH, Xu H and Li JD (2007) Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice.PLoS ONE 2 e1032
Lim JH, Lee JC, Lee YH, Choi IY, Oh YK, Kim HS, Park JS and Kim WK (2006) Simvastatin prevents oxygen and glucose deprivation/reoxygenation-induced death of cortical neurons by reducing the production and toxicity of 4-hydroxy-2E-nonenal. Journal of Neurochemist97 140-150
Lim JH, Stirling B, Derry J, Koga T, Jono H, Woo CH, Xu H, Bourne P, Ha UH, Ishinaga H, Xu H, Andalibi A, Feng XH, Zhu H, Huang Y, ZHang W, Weng X, Yan C, Yin Z, Briles DE, Davis RJ, Flavell RA and Li JD (2007) Tumor suppressor CYLD regulates acute lung injury in lethal Streptococcus pneumoniae infections.Immunity 27 349-360
Lim JW, Kim H and Kim KH (2001) NF-kB, inducible nitric oxide synthase and apoptosis by Helicobacter pylori infection. Free Radical Biology and Medicine 31 355-366
Lim JW, Kim H and Kim KH (2001) Nuclear factor-kB regulates cyclooxygenase-2 expression and cell proliferation in human gastric cancer cells. Laboratory Investigation 81 349-360
Lim JW, Kim H and Kim KH (2002) Expressions of Ku70 and Ku80 mediated by NF-kB and cyclooxygenase-2 are related to cell proliferation in human gastric cancer cells. Journal of Biological Chemistry 277 46093-46100
Lim JW, Kim H and Kim KH (2003) Ku antigen-RBP-Jk complex binds to NF-kB p50 promoter and acts as a positive regulator of p50 expression in human gastric cancer cells. Journal of Biological Chemistry 279 231-237
Lim JW, Kim KH and Kim H (2008) NF-kB p65 regulates nuclear translocation of Ku70 via degradation of heat shock cognate protein 70 in pancreatic acinar AR42J cells. International Journal of Biochemistry and Cell Biology in press
Lim KM, Yeo WS and Chow VT (2004) Antisense abrogation of DENN expression induces apoptosis of leukemia cells in vitro, causes tumor regression in vivo and alters the transcription of genes involved in apoptosis and the cell cycle. International Journal of Cancer 109 24-37
Lim KT (2005) Glycoprotein isolated from Solanum nigrum L. kills HT-29 cells through apoptosis. Journal of Medicine and Food 8 215-226
Lim MS and Elenitoba-Johnson KS (2004) Ubiquitin ligases in malignant lymphoma. Leukemia and Lymphoma 45 1329-1339
Lim M-Y, Davis N, Zhang J and Bose Jr HR (1990) The v-rel oncogene product is complexed with cellular proteins including its proto-oncogene product and heat shock protein 70. Virology 175 149-160
Lim R, Zaheer A, Yorek MA, Darby CJ and Oberley LW (2000) Activation of nuclear factor-kB in C6 rat glioma cells after transfection with glia maturation factor. Journal of Neurochemistry 74 596-602
Lim S, Kang KW, Park SY, Kim SI, Choi YS, Kim ND, Lee KU, Lee HK and Pak YK (2004) Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase expression by a novel compound, mercaptopyrazine, through suppression of nuclear factor-kB binding to DNA. Biochemical Pharmacology 68 719-728
Lim SP and Garzino-Deomo A (2000) The human immunodeficiency virus type 1 Tat protein up-regulates the promoter activity of the beta-chemokine monocyte chemoattractant protein 1 in the human astrocytoma cell line U-87 MG: role of SP-1, AP-1, and NF-kB consensus sites. Journal of Virology 74 1632-1640
Lim SW, Li C, Ahn KO, Kim J, Moon IS, Ahn C, Lee JR and Yang CW (2005) Cyclosporine-induced renal injury induces Toll-like receptor and maturation of dendritic cells. Transplantation 80 691-699
Lim W, Jung J, Surh Y, Inoue H and Lee Y (2007) Hypertonic sodium choloride and mannitol induces COX-2 via different signaling pathways in mouse cortical collecting duct M-1 cells.
Life Sciences in press
Lim WC, Park M, Bahn JJ, Inoue H and Lee YJ (2005) Hypertonic sodium chloride induction of cyclooxygenase-2 occurs independently of NF-kB and is inhibited by the glucocorticoid receptor in A549 cells. FEBS Letters 579 5430-5436
Lim Y, Levy M and Bray TM (2004) Dietary zinc alters early inflammatory responses during cutaneous wound healing in weanling CD-1 mice. Journal of Nutrition 134 811-816
Lima LL, Goncalves PF, Sallum EA, Casati MZ adn Nociti Jr FH (2008) Guided tissue regeneration may modulate gene expression in periodontal intrabony defects: a human study. Journal of Periodontal Research in press
Limbourg FP, Staedler H, Chinnadurai G, Baeuerle PA and Schmitz L (1996) A hydrophobic region within the adenovirus E1B 19 kDa protein is necessary for the transient activation of NF-kB by different stimuli. Journal of Biological Chemistry 271 20392-20398
Limon-Pacheco JH, Hernandez NA, Fanjul-Moles ML and Gonsebatt ME (2007) Glutathione depletion activates mitogen-activated protein kinase (MAPK) pathways that display organ-specific responses and brain protection in mice. Free RadicalBiology & Medicine 43 1335-1347
Limtakul P (2007) Curcumin as chemosensitizer. Advances in Experimental Medicine and Biology 595 269-300
Lin A (2003) Activation of the JNK signaling pathway: Breaking the brake on apoptosis. BioEssays 25 17-24
Lin A (2006) A five-year itch in TNF-a cytotoxicity: the time factor determines JNK action. Developmental Cell 10 277-278
Lin A and Dibling B (2003) The true face of JNK activation in apoptosis. Aging Cell 1 112-116
Lin A and Karin M (2003) NF-kB in cancer: a marked target. Seminars in Cancer Biology 13 107-114
Lin B, Williams-Skipp C, Tao Y, Schleicher MS, Cano LL, Duke RC and Scheinman RI (1999) NF-kB functions as both a proapoptotic and antiapoptotic regulatory factor within a single cell type. Cell Death & Differentiation 6 570-582
Lin C, Kuan I, Wang C, Lee H, Lee W, Sheu J, Hsiao G, Wu C and Kuo H (2002) Lipoteichoic acid-induced cyclooxygenase-2 expression requires activations of p44/42 and p38 mitogen-activated protein kinase signal pathways. European Journal of Pharmacology 450 1-9
Lin C, Wei W, Zhang J, Liu S, Liu Y and Zheng D (2007) Formyl peptide receptor-like 1 mediated endogenous TRAIL gene expression with tumoricidal activity.Molecular Cancer Therapeutics 6 2618-2625
Lin CC, Chang LL, Lin CH, Shih CH, Liao YT, Hsu MJ and Chen BC (2007) Transforming growth factor-beta1 stimulates heme oxygenase-1 expression via the PI3K/Akt and NF-kB pathways in human lung epithelial cells. European Journal ofPharmacology in press
Lin CC, Hsiao LD, Chien CS, Lee CW, Hsieh JT and Yang CM (2004) Tumor necrosis factor-alpha-induced cyclooxygenase-2 expression in human tracheal smooth muscle cells: involvement of p42/p44 and p38 mitogen-activated protein kinases and nuclear factor-kB. Cellular Signaling 16 597-607
Lin CC, Lee CW, Chu TH, Cheng CY, Luo SF, Hsiao LD and Yang CM (2007) Transactivation of Src, PDGF receptor, and Akt is involved in IL-1beta-induced ICAM-1 expression in A549 cells.
Journal of Cellular Physiology in press
Lin CC, Lin CY, Ma HY (2000) Pulmonary function changes and increased Th-2 cytokine expression and nuclear factor kB activation in the lung after sensitization and allergen challenge in brown Norway rats. Immunology Letters 73 57-64
Lin CC, Sun CC, Luo SF, Tsai AC, Chien CS, Hsiao LD, Lee CW, Hsieh JT and Yang CM (2004) Induction of cyclooxygenase-2 expression in human tracheal smooth muscle cells by interleukin-1beta: involvement of p42/p44 and p38 mitogen-activated protein kinases and nuclear factor-kB. Journal of Biomedical Science 11 377-390
Lin CC, Tseng HW, Hsieh HL, Lee CW, Wu CY, Cheng CY and Yang CM (2008) Tumor necrosis factor-alpha induces MMP-9 expression via p42/p44 MAPK, JNK, and nuclear factor-kB in A549 cells. Toxicology and Applied Pharmacology in press
Lin CF, Chiu SC, Hsiao YL, Wan SW, Lei HY, Shiau AL, Liu HS, Yeh TM, Chen SH, Liu CC, Lin YS (2005) Expression of cytokine, chemokine, and adhesion molecules during endothelial cell activation induced by antibodies against Dengue virus nonstructural protein 1. Journal of Immunology 174 395-403
Lin CH, Chang CW, Wang CC, Chang MS and Yang LL (2002) Byakangelicol, isolated from Angelica dahurica, inhibits both the activity and induction of cyclooxygenase-2 in human pulmonary epithelial cells. J Pharm Pharmacol 54 1271-1278
Lin CH, Cheng HW, Hsu MJ, Chen MC, Lin CC and Chen BC (2006) c-Src mediates thrombin-induced NF-kB activation and IL-8/CXCL8 expression in lung epithelial cells. Journal of Immunology 177 3427-3438
Lin CH, Sheu SY, Lee HM, Ho YS, Lee WS, Ko WC and Sheu JR (2000) Involvement of protein kinase C-gamma in IL-1beta-induced cyclooxygenase-2 expression in human pulmonary epithelial cells. Molecular Pharmacology 57 36-43
Lin CM, Huang ST, Liang YC, Lin MS, Shih CM, Chang YC, Chen TY and Chen CT (2005) Isovitexin suppresses lipopolysaccharide-mediated inducible nitric oxide synthase through inhibition of NF-kB in mouse macrophages. Planta Medica 71 748-753
Lin CP, Chen YH, Chen JW, Leu HB, Liu TZ, Liu PL and Huang SL (2007) Cholestin (Monascus purpureus rice) inhibits homocysteine-induced reactive oxygen species generation, nuclear factor-kB activation, and vascular cell adhesion molecule-1 expression in human aortic endothelial cells. Journal of Biomedical Science in press
Lin CT, Chen CJ, Lin TY, Tung JC and Wang SY (2008) Anti-inflammation activity of fruit essential oil from Cinnamomum insularimontanum Hayata. Bioresource Technology in press
Lin CW, Chen LJ, Lee PL, Lee CI, Lin JC and Chiu JJ (2006) The inhibition of TNF-a-induced E-selectin expression in endothelial cells via the JNK/NF-kB pathways by highly N-acetylated chitooligosaccharides. Biomaterials in press
Lin CW and Ting AT (2006) Transglutaminase-catalyzed site-specific conjugation of small-molecule probes to proteins in vitro and on the surface of living cells. Journal of the American Chemical Society 128 4542-4543
Lin CW, Tu PF, Hsiao NW, Chang CY, Wan L, Lin YT and Chang HW (2007) Identification of a novel septin 4 protein binding to human herpesvirus 8 kaposin A protein using a phage display cDNA library. Journal of VirologicalMethods 143 65-72
Lin CY, Liang YC and Yung BY (2006) Nucleophosmin/B23 regulates transcriptional activation of E2F1 via modulating the promoter binding of NF-kB, E2F1 and pRB.Cellular Signaling 18 2041-2048
Lin FS, Lin CC, Chien CS, Luo SF and Yang CM (2004) Involvement of p42/p44 MAPK, JNK, and NF-kB in IL-1beta-induced ICAM-1 expression in human pulmonary epithelial cells. Journal of Cell Physiology 202 464-473
Lin H, Chen C and Chen BD (2001) Resistance of bone marrow-derived macrophages to apoptosis is associated with the expression of X-linked inhibitor of apoptosis protein in primary cultures of bone marrow cells. Biochemistry Journal 353 299-306
Lin H, Cheng CF, Hou HH, Oian WS, Chao YC, Ciou YY, Djoko B, Tsai MT, Cheng CJ and Yang RB (2008) Disruption of guanylyl cyclase-G protects against acute renal injury. Journal of The American Socieity of Nephrology in press
Lin H, Hou CC, Cheng CF, Chiu TH, Hsu YH, Sue YM, Chen TH, Hou HH, Chao YC, Cheng TH and Chen CH (2007) Peroxisomal proliferator-activated receptor-alpha (PPAR-{alpha}) protects renal tubular cells from adriamycin-induced apoptosis.
Molecular Pharmacology in press
Lin H, Wada K, Yonezawa M, Shinoki K, Akamatsu T, Tsukui T and Sakamoto C (2003) Tomoregulin ectodomain shedding by proinflammatory cytokines. Life Sciences 73 1617-1627
Lin H, Xiao J, Luo X, Wang H, Gao H, Yang B and Wang Z (2007) Overexpression HERG K(+) channel gene mediates cell-growth signals on activation of oncoproteins SP1 and NF-kB and inactivation of tumor suppressor Nkx3.1. Journal of Cellular Physiology in press
Lin HC, Hickey M, Hsu L, Medina D and Rabson AB (2005) Activation of human T cell leukemia virus type 1 LTR promoter and cellular promoter elements by T cell receptor signaling and HTLV-1 Tax expression. Virology 339 1-11
Lin HY, Wang CL, Hsiao PJ, Yung-Chuan L, Chen SY, Lin KOD, Hsin SC, Hsieh MC and Shin SJ (2007) SUMO4 M55V variant is associated with diabetic nephropathy in type 2 diabetes. Diabetes in press
Lin J and Yan GT (2003) Function of eukaryotic transcription factor NF-kB in the signal transduction of acute inflammatory response [Article in Chinese]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 15 45-48
Lin JC, Cherng JM, Lin HJ, Tsang CW, Liu YX and Lee SP (2004) Amino acid changes in functional domains of latent membrane protein 1 of Epstein-Barr virus in nasopharyngeal carcinoma of southern China and Taiwan: prevalence of an HLA A2-restricted ‘epitope-loss variant’. Journal of General Virology 85 2023-2034
Lin JK (2004) Suppression of protein kinase C and nuclear oncogene expression as possible action mechanisms of cancer chemoprevention by curcumin. Archives of Pharmacology Research 27 683-692
Lin JK (2007) Molecular targets of curcumin. Advances in Experimental Medicine and Biology 595 227-243
Lin JK and Tsai SH (1999) Chemoprevention of cancer and cardiovascular disease by resveratrol. Proc Natl Sci Counc Repub China B 23 99-106
Lin JP, Lu HF, Lee JH, Lin JG, Hsia TC, Wu LT and Chung JG (2005) (-)-Menthol inhibits DNA topoisomerases I, II alpha and beta and promotes NF-kB expression in human gastric cancer SNU-5 cells. Anticancer Research 25 2069-2074
Lin K-I, Baraban JM and Ratan RR (1998) Inhibition versus induction of apoptosis by proteasome inhibitors depends on concentration. Cell Death & Differentiation 5 577-583
Lin K-I, DiDonato JA, Hoffman A, Hardwick JM and Ratan RR (1998) Suppression of steady-state, but not stimulus-induced NF-kB activity inhibits alphavirus-induced apoptosis. Journal of Cell Biology 141 1479-1487
Li K-I, Kao YY, Kuo HK, Yang WB, Chou A, Lin HH, Yu AL and Wong CH (2006) Reishi polysaccharides induce immunoglobulin production through the TLR4/TLR2-mediated induction of transcription factor blimp-1. Journal of Biological Chemistry 281 24111-24123
Lin K-I, Lee S-H, Narayanan R, Baraban JM, Hardwick JM and Ratan RR (1995) Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kB. Journal of Cell Biology 131 1149-1161
Lin L (2006) RAGE on the Toll road? Cellular & Molecular Immunology 3 351-358
Lin L, Brody SL and Peng SL (2005) Restraint of B cell activation by Foxj1-mediated antagonism of NF-kB and IL-6. Journal of Immunology 175 951-958
Lin L and Ghosh S (1996) A glycine-rich region in NF-kB p105 functions as a processing signal for the generation of the p50 subunit. Molecular and Cellular Biology 16 2248-2254
Lin L, DeMartino GN and Greene WC (1998) Cotranslational biogenesis of NF-kB p50 by the 26S proteasome. Cell 92 819-828
Lin L, DeMartino GN, Greene WC (2000) Cotranslational dimerization of the rel homology domain of NF-kB1 generates p50-p105 heterodimers and is required for effective p50 production. EMBO Journal 19 4712-4722
Lin L, Hron JD and Peng SL (2004) Regulation of NF-kB, th activation, and autoinflammation by the forkhead transcription factor foxo3a. Immunity 21 203-213
Lin L and Kobayashi M (2003) Stability of the Rel homology domain is critical for generation of NF-kB p50 subunit. Journal of Biological Chemistry 278 31479-31485
Lin L and Peng SL (2006) Coordination of NF-kB and NFAT antagonism by the Forkhead transcription factor Foxd1. Journal of Immunology 176 4793-4803
Lin L, Spoor MS, Gerth AJ, Brody SL and Peng SL (2004) Modulation of Th1 activation and inflammation by the NF-kB repressor Foxj1. Science 303 1017-1020
Lin M and Rikihisa Y (2004) Ehrlichia chaffeensis downregulates surface Toll-like receptors 2/4, CD14 and transcription factors PU.1 and inhibits lipopolysaccharide activation of NF-kB, ERK 1/2 and p38 MAPK in host monocytes. Cellular Microbiology 6 175-186
Lin MT, Chang CC, Chen ST, Chang HL, Su JL, Chau YP and Kuo ML (2004) Cyr61 expression confers resistance to apoptosis in breast cancer MCF-7 cells by a mechanism of NF-kB-dependent XIAP up-regulation. Journal of Biological Chemistry 279 24015-24023
Lin MT, Zuon CY, Chang CC, CHen ST, Chen CP, Lin BR, Wang MY, Jeng YM, CHang KJ, Lee PH, CHen WJ and Kuo ML (2005) Cyr61 induces gastric cancer cell motility/invasion via activation of the integrin/nuclear factor-kB/cyclooxygenase-2 signaling pathway. Clinical Cancer Research 11 5809-5820
Lin MW, Tsao LT, Chang LC, Chen YL, Huang LJ, Kuo SC, Tzeng CC, Lee MR and Wang JP (2007) Inhibition of lipopolysaccharide-stimulated NO production by a novel synthetic compound CYL-4d in RAW 264.7 macrophages involving the blockade of MEK4/JNK/AP-1 pathway. Biochemical Pharmacology 73 1796-1806
Lin MW, Tsao LT, Huang LJ, Kuo SC, Weng JR, Ko HH, Lin CN, Lee MR and Wang JP (2006) Inhibition of lipopolysaccharide-stimulated NO production by crotafuran B in RAW 264.7 macrophages involves the blockade of NF-kB activation through the increase in IkBa synthesis. Toxicology and Applied Pharmacology 210 108-115
Lin MW, Yang SR, Huang MH and Wu SN (2004) Stimulatory actions of caffeic acid phenethyl ester, a known inhibitor of NF-kB activation, on Ca2+-activated K+ current in pituitary GH3 cells. Journal of Biological Chemistry 279 26885-26892
Lin N, Liu C, Xiao C, Jia H, Imada K, Wu H and Ito A (2006) Triptolide, a diterpenoid triepoxide, suppresses inflammation and cartilage destruction in collagen-induced arthritis mice. Biochemical Pharmacology 73 136-146
Lin N, Uchi H, Moroi Y, Fukiwake N, Dainichi T, Takeuchi S, Takahara M, Tu Y, Furue M and Urabe K (2007) Expression of the p38 MAPK, NF-kB and cyclin D1 in extramammary Paget’s disease. Journal of Dermatological Science 45 187-192
Lin P, Huang LH and Steward R (2000) Cactin, a conserved protein that interacts with the Drosophila IkB protein cactus and modulates its function. Mechanisms of Development 94 57-65
Lin P and Ye RD (2003) The lysophospholipid receptor G2A activates a specific combination of G proteins and promotes apoptosis. Journal of Biological Chemistry 278 14379-14786
Lin PW, Simon PO, Gewirtz AT, Neish AS, Ouellette AJ, Madara JL and Lencer WI (2004) Paneth cell cryptdins act in vitro as apical paracrine regulators of the innate inflammatory response. Journal of Biological Chemistry 279 19902-19907
Lin QY, Jin LJ, Cao ZH, Li HQ and Xu YP (2008) Protective effect of Acanthopanax senticosus extract against endotoxic shock in mice. Journal of Ethnopharmacology in press
Lin QY, Jin LJ, Cao ZH and Xu YP (2008) Inhibition of inducible nitric oxide synthase by Acanthopanax senticosus extract in RAW264.7 macrophages. Journal of Ethnopharmacology in press
Lin R, Beauparlant P, Makris C, Meloche S and Hiscott J (1996) Phosphorylation of IkBa in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability. Molecular and Cellular Biology 16 1401-1409
Lin R, Gewert D and Hiscott J (1995) Differential transcriptional activation in vitro by NF-kB/Rel proteins. Journal of Biological Chemistry 270 3123-3131
Lin R, Heylbroeck C, Genin P, Pitha PM and Hiscott J (1999) Essential role of interferon regulatory factor 3 in direct activation of RANTES chemokine transcription. Molecular and Cellular Biology 19 959-966
Lin R, Liu J and Gan W (2004) Protection of vascular endothelial cells from TNF-a induced injury by quercetin [Article in Chinese]. Zhong Yao Cai 27 597-599
Lin R, Liu J, Gan W and Ding C (2007) Protective effect of quercetin on the homocysteine-injured human umbilical vein vascular endothelial cell line (ECV304). Basic & Clinical Pharmacology & Toxicology 101 197-202
Lin R, Liu J, Peng N, Yang G, Gan W and Wang L (2005) Lovastatin reduces nuclear factor kB activation induced by C-reactive protein in human vascular endothelial cells. Biol Pharm Bull 28 1630-1634
Lin RJ, Liao CL and Lin YL (2004) Replication-incompetent virions of Japanese encephalitis virus trigger neuronal cell death by oxidative stress in a culture system. Journal of General Virology 85 521-533
Lin S, Cox HJ, Rhodes PG and Cai Z (2006) Neuroprotection of alpha-phenyl-n-tert-butyl-nitrone on the neonatal white matter is associated with anti-inflammation. Neuroscience Letters 405 52-56
Lin S, Wu M, Xu Y, Xiong W, Yi Z, Zhang X and Zhenghong Y (2007) Inhibition of hepatitis B virus replication by MyD88 is mediated by nuclear factor-kB activation. Biochimica et Biophysica Acta 1772 1150-1157
Lin SC, Chung JY, Lamothe B, Rajashankar K, Lu M, Lo YC, Lam ZY, Darnay BG and Wu H (2007) Molecular basis for the unique deubiquitinating activity of the NF-kB inhibitor A20. Journal of Molecular Biology in press
Lin SC, Liu CJ, Chiu CP, Chang SM, Lu SY and Chen YJ (2004) Establishment of OC3 oral carcinoma cell line and identification of NF-kB activation responses to areca nut extract. Journal of Oral Pathology and Medicine 33 79-86
Lin SC, Liu CJ, Yeh WI, Lui MT, Chang KW and Chang CS (2005) Functional polymorphism in NFKB1 promoter is related to the risks of oral squamous cell carcinoma occurring on older male areca (betel) chewers. Cancer Letters 2243 47-54
Lin SC, Lu SY, Lee SY, Lin CY, Chen CH and Chang KW (2005) Areca (betel) nut extract activates mitogen-activated protein kinasesand NF-kB in oral keratinocytes. International Journal of Cancer 116 526-535
Lin S-C and Stavnezer J (1996) Activation of NF-kB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cg1 promoter. Molecular and Cellular Biology 16 4591-4603
Lin S-C, Wortix HH and Stavnezer J (1998) The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to G1 is explained by differential induction of NF-kB/Rel proteins. Molecular and Cellular Biology 18 5523-5532
Lin SJ, Chen YH, Lin FY, Hsieh LY, Wang SH, Lin CY, Wang YC, Ku HH, Chen JW and Chen YL (2007) Pravastatin induces thrombomodulin expression in TNFa-treated human aortic endothelial cells by inhibiting Rac1 and Cdc42 translocation and activity. Journal of Cellular Biochemistry 101 642-653
Lin ST, Wang Y, Xue Y, Feng DC, Xu Y and Xu LY (2008) Tetrandrine suppresses LPS-induced astrocyte activation via modulating IKKs-IkBa-NF-kB signaling pathway. Molecular and Cellular Biochemistry in press
Lin SJ, Shyue SK, Hung YY, Chen YH, Ku HH, Chen JW, Tam KB and Chen YL (2005) Superoxide dismutase inhibits the expression of vascular cell adhesion molecule-1 and intracellular cell adhesion molecule-1 induced by tumor necrosis factor-alpha in human endothelial cells through the JNK/p38 pathways. Arteriosclerosis, Thrombosis and Vascular Biology 25 334-340
Lin SJ, Shyue SK, Liu PL, Chen YH, Ku HH, Chen JW, Tam KB and Chen YL (2004) Adenovirus-mediated overexpression of catalase attenuates oxLDL-induced apoptosis in human aortic endothelial cells via AP-1 and C-Jun N-terminal kinase/extracellular signal-regulated kinase mitogen-activated protein kinase pathways. Journal of Molecular and Cellular Cardiology 36 129-139
Lin SJ, Shyue SK, Shih MC, Chu TH, CHen YH, Ku HH, Chen JW, Tam KB and Chen YL (2007) Superoxide dismutase and catalase inhibit oxidized low-density lipoprotein-induced human aortic smooth muscle cell proliferation: role of cell-cycle regulation, mitogen-activated protein kinases, and transcription factors.Atherosclerosis 190 124-134
Lin TH, Yang RS, Tang CH, Lin CP and Fu WM (2007) PPARgamma inhibits osteogenesis via the down-regulation of the expression of COX-2 and iNOS in rats. Bone in press
Lin Th, Yang RS, Tang CH, Wu MY and Fu WM (2008) Regulation of the maturation of osteoblasts and osteoclastogenesis by glutamate. European Journal of Pharmacology in press
Lin WN, Luo SF, Lee CW, Wang CC, Wang JS and Yang CM (2007) Involvement of MAPKs and NF-kB in LPS-induced VCAM-1 expression in human tracheal smooth muscle cells. Cellular Signaling 19 1258-1267
Lin WN, Luo SF, Wu CB, Lin CC and Yang CM (2007) Lipopolysaccharide induces VCAM-1 expression and neutrophil adhesion to human tracheal smooth muscle cells: Involvement of Src/EGFR/PI3-K/Akt pathway. Toxicology and Applied Pharmacology in press
Lin X, Cunningham Jr ET, Mu Y, Geleziunas R and Greene WC (1999) The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-kB acting through the NF-kB-inducing kinase and IkB kinases. Immunity 10 271-280
Lin X, Irwin D, Kanazawa S, Huang L, Romeo J, Yen TS and Peterlin BM (2003) Transcriptional profiles of latent human immunodeficiency virus in infected individuals: effects of Tat on the host and reservoir. Journal of Virology 77 8227-8236
Lin X, LI Q, Wang YJ, Ju YW, Chi ZQ, Wang MW and Liu JG (2007) Morphine inhibits doxorubicin-induced reactive oxygen species generation and nuclear factor-kB transcriptional activation in neuroblastoma SH-SY5Y cells. Biochemical Journal in press
Lin X, Mu Y, Cunningham ET, Marcu KB, Geleziunas RG and Greene WC (1998) Molecular determinants of NF-kB-inducing kinase action. Molecular and Cellular Biology 18 5899-5907
Lin X, O’Mahoney A, Mu Y, Geleziunas R and Greene WC (2000) Protein kinase C-theta participates in NF-kB activation induced by CD3-CD28 costimulation through selective activation of IkB kinase b. Molecular and Cellular Biology 20 2933-2940
Lin X, and Wang D (2004) The roles of CARMA1, Bcl10, and MALT1 in antigen receptor signaling. Seminars In Immunology 16 429-435
Lin Y, Bright AC, Rothermel TA and He B (2003) Induction of apoptosis by paramyxovirus simian virus 5 lacking a small hydrophobic gene. Journal of Virology 77 3371-3383
Lin Y, Choski S, Shen HM, Yang QF, Hur GM, Kim YS, Tran JH, Nedospasov SA and Liu ZG (2003) TNF induced non-apoptotic cell death requires RIP mediated cellular reactive oxygen species accumulation. Journal of Biological Chemistry 279 10822-10828
Lin Y, Devin A, Rodriguez Y and Liu ZG (1999) Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes & Development 13 2514-2526
Lin Y, Ryan J, Lewis J, Wani MA, Lingrel JB and Liu ZG (2003) TRAF2 exerts its antiapoptotic effect by regulating the expression of Kruppel-like factor LKLF. Molecular and Cellular Biology 23 5849-5856
Lin Y, Sun M, Fuentes SM, Keim CD, Rothermel T and He B (2007) Inhibition of interleukin-6 expression by the V protein of parainfluenza virus 5. Virology 368 262-272
Lin Y-C, Brown K and Siebenlist U (1995) Activation of NF-kB requires proteolysis of the inhibitor IkB-a: signal-induced phosphorylation of IkB-a alone does not release active NF-kB. Proceedings of the National Academy of Sciences USA 92 552-556
Lin YC, Liaang YC, Sheu MY, Lin YC, Hsieh MS, Chen TF and Chen CH (2008) Chondroprotective effects of glucosamine involving the p38 MAPK and Akt signaling pathways. Rheumatology International in press
Lin YC, Shun CT, Wu MS and Chen CC (2006) A novel anticancer effect of thalidomide: inhibition of intercellular adhesion molecule-1-mediated cell invasion and metastasis through suppression of nuclear factor-kB. ClinicalCancer Research 12 7165-7173
Lin YC, Uang HW, Lin RJ, Chen IJ and Lo YC (2007) Neuroprotective effects of GLNVA against microglia-like cells and 6-OHDA-induced neurotoxicity in SH-SY5Y human dopaminergic neuroblastoma cells. Journal of Pharmacology and ExperimentalTherapeutics in press
Lin YG, Kunnumakkara AB, Nair A, Merritt WM, Han LY, Armaiz-Pena GN, Kamat AA, Spannuth WA, Gershenson DM, Lutgendorf SK, Aggarwal BB and Sood AK (2007) Curcumin inhibits tumor growth and angiogenesis in ovarian carcinoma by targeting the nuclear factor-kB pathway. Clinical Cancer Research 13 3423-3430
Lin YL, Liang YC and Chiang BL (2007) Placental growth factor down-regulates type 1 T helper immune response by modulating the function of dendritic cells.Journal of Leukocyte Biology in press
Lin YL, Liang YC, Lee SS and Chiang BL (2005) Polysaccharide purified from Ganoderma lucidum induced activation and maturation of human monocyte-derived dendritic cells by the NF-kB and p38 mitogen-activated protein kinase pathways. Journal of Leukocyte Biology 78 533-543
Lin YL and Lin JK (1997) (-)-epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kB. Molecular Pharmacology 52 465-472
Lin YL, Tsai SH, Lin-Shiau SY, Ho CT and Lin JK (1999) Theaflavin-3,3′-digallate from black tea blocks the nitric oxide synthase by down-regulating the activation of NF-kB in macrophages. European Journal of Pharmacology 367 379-388
Lin YX, Xu RS, Jiang XD, Kang DZ, Ke YQ, Du MX, Cai YQ and Qin LS (2006) Effect of N-acetyl-cysteine and depakine pretreatment on ferrous chloride-induced membrane potential and peroxidate changes in rat cortex neurons [Article in Chinese]. Nan Fang Yi Ke Da Xue Xue Bao 26 448-451
Lin Y-Z, Yao S, Veach RA, Torgerson TR and Hawiger J (1996) Inhibition of nuclear translocation of transcription factor NF-kB by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence. Journal of Biological Chemistry 270 14255-14258
Lin Z, Crockett DK, Jenson SD, Lim MS and Elenitoba-Johnson KS (2004) Quantitative proteomic and transcriptional analysis of the response to the p38 MAPK inhibitor SB203580 in transformed follicular lymphoma cells. Mol Cell Proteomics 3 820-833
Lin Z, Hamik A, Jain R, Kumar A and Jain MK (2006) Kruppel-Like factor 2 inhibits protease activated receptor-1 expression and thrombin-mediated endothelial activation. Arteriosclerosis, Thrombosis, and Vascular Biology 26 1185-1189
Lin Z, Zhu D, Yan Y and Yu B (2008) Herbal formula FBD extracts prevented brain injury and inflammation induced by cerebral ischemia-reperfusion. Journal of Ethnopharmacology in press
Lindard C, Gremy O and Benderitter M (2007) Reduction of PPAR{gamma} expression by gamma-irradiation as a mechanism contributing to inflammatory response in rat colon: Modulation by the 5-ASA agonist. Journal of Pharmacology and Experimental Therapeutics in press
Linard C, Marquette C, Mathieu J, Pennequin A, Clarencon D and Mathe D (2004) Acute induction of inflammatory cytokine expression after gamma-irradiation in the rat: Effect of an NF-kB inhibitor. Int J Radiat Oncol Biol Phys 58 427-434
Linard C, Ropenga A, Vozenin-Brotons MC, Chapel A and Mathe D (2003) Abdominal irradiation increases inflammatory cytokine expression and activates NF-kB in rat ileal muscularis layer. American Journal of Physiology: Gastrointestinal Liver Physiology 285 G556-G565
Linardopoulos S (2007) Aurora-A kinase regulates NF-kB activity: lessons from combination studies. J Buon 12 S67-S70
Lind DS, Hochwald SN, Malaty J, Rekkas S, Hebig P, Mishra G, Moldawer LL, Copeland 3rd EM and Mackay S (2001) Nuclear factor-kB is upregulated in colorectal cancer. Surgery 130 363-369
Lind EF, Ahonen CL, Wasiuk A, Kosaka Y, Becher B, Bennett KA and Noelle RJ (2008) Dendritic cells require the NF-kB2 pathway for cross-presentation of soluble antigens. Journal of Immunology 181 354-363
Lind MH, Rozell B, Wallin RP, Van Hogerlinden M, Ljunggren HG, Toftgard R and Sur I (2004) Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced by NF-kB inhibition. Proceedings of the National Academy of Sciences USA 101 4972-4977
Lindberg MK, Erlandsson M, Alatalo SL, Windahl S, Andersson G, Halleen JM, Carlsten H, Gustafsson JA and Ohlsson C (2001) Estrogen receptor alpha, but not estrogen receptor beta, is involved in the regulation of the OPG/RANKL (osteoprotegerin/receptor activator of NF-kB ligand) ratio and serum interleukin-6 in male mice. Journal of Endocrinology 171 425-433
Lindeman JH, Abdul-Hussien H, Schaapherder AF, van Bockel JH, von der Thusen JH, Roelen DL and Kleemann R (2007) Enhanced expression and activation of pro-inflammatory transcription factors distinguish aneurismal from atherosclerotic aorta: IL-6 and IL-8 dominated inflammatory responses prevail in the human aneurysm. Clinical Sciences (London) in press
Lindemans CA, Coffer PJ, Schellens IM, de Graaff PM, Kimpen JL and Koenderman L (2006) Respiratory syncytial virus inhibits granulocyte apoptosis through a phosphatidylinositol 3-kinase and NF-kB-dependent mechanism. Journal ofImmunology 176 5529-5537
Linden A (2007) A role for the cytoplasmic adaptor protein Act1 in mediating IL-17 signaling. Sci STKE 398 re4
Lindenmeyer MT, Hrenn A, Kern C, Castro V, Murillo R, Muller S, Laufer S, Schulte-Monting J, Siedle B and Merfort I (2005) Sesquiterpene lactones as inhibitors of IL-8 expression in HeLa cells. Bioorganic Medicinal Chemistry 14 2487-2497
Linderson Y, Bresso F, Buentke E, Pettersson S and D’Amato M (2005) Functional interaction of CARD15/NOD2 and Crohn’s disease-associated TNFa polymorphisms. International Journal of Colorectal Disease 20 305-311
Linderson Y, Cross D, Neurath MF and Pettersson S (1997) NFE, a new transcriptional activator that facilitates p50 and c-Rel-dependent IgH 3′ enhancer activity. European Journal of Immunology 27 468-475
Lindgren H, Olsson AR, Pero RW and Leanderson T (2003) Differential usage of IkBa and IkBb in regulation of apoptosis versus gene expression. Biochemical and Biophysical Research Communications 301 204-211
Lindgren H, Pero RW, Ivars F and Leanderson T (2001) N-substituted benzamides inhibit nuclear factor-kB and nuclear factor of activated T cells activity while inducing activator protein 1 activity in T lymphocytes. Molecular Immunology 38 267-277
Lindholm PF, Bub J, Kaul S, Shidham VB and Kajdacsy-Balla A (2000) The role of constitutive NF-kB activity in PC-3 human prostate cancer cell invasive behavior. Clinical and Experimental Metastasis 18 471-479
Lindholm PF, Marriott SJ, Gitlin SD, Bohan CA and Brady JN (1990) Induction of nuclear NF-kB DNA binding activity after exposure of lymphoid cells to soluble tax1 protein. New Biologist 2 1034-1043
Lindholm PF, Reid RL and Brady JN (1992) Extracellular Tax1 protein stimulates tumor necrosis factor-b and immunoglobulin kappa light chain expression in lymphoid cells. Journal of Virology 66 1294-1302
Lindholm PF, Tamami M, Makowski J and Brady JN (1996) Human T-cell lymphotropic virus type 1 Tax1 activation of NF-kB: involvement of the protein kinase C pathway. Journal of Virology 70 2525-2532
Lindholm J, Ljungman AG and Tagesson C (2005) Interferon gamma-induced gene expression of the novel secretory phospholipase A(2) rype IID in human monocyte-derived macrophages is inhibited by lipopolysaccharide. Inflammation 29 108-117
Lindkvist A, Ivarsson K, Jernberg-Wiklund H and Paulsson-Karlsson Y (2006) Interferon-induced sensitization to apoptosis is associated with repressed transcriptional activity of the hTERT promoter in multiple myeloma. Biochemical and Biophysical Research Communications 341 1141-1148
Lindner I, Torrvellas-Farcia J, Kolonias D, Carlson LM, Tolba KA, Plano GV and Lee KP (2007) Modulation of dendritic cell differentiation and function by YopJ of Yersinia pestis. European Journal of Immunology in press
Lindner V (1998) The NF-kB and IkB system in injured arteries. Pathobiology 66 311-320
Lindroos PM, Rice AB, Wang YZ and Bonner JC (1998) Role of Nuclear Factor-kB and mitogen-activated protein kinase signaling pathways in IL-1 b-mediated induction of a-PDGF receptor expression in rat pulmonary myofibroblasts. Journal of Immunology 161 3464-3468
Lindroos PM, Wang YZ, Rice AB and Bonner JC (2001) Regulation of PDGFR-alpha in rat pulmonary myofibroblasts by staurosporine. American Journal of Physiology: Lung Cellular and Molecular Physiology 280 L354-362
Lindros KO, Jokelainen K and Nanji AA (1999) Acetaldehyde prevents nuclear factor-kB activation and hepatic inflammation in ethanol-fed rats. Laboratory Investigation 79 799-806
Lindstrom TM and Bennett PR (2005) 15-deoxy-delta12,14-prostaglandin J2 inhibits IL-1beta-induced NF-kB in human amnion and myometrial cells: mechanisms and implications. Journal of Clinical Endocrinology and Metabolism 90 3534-3543
Lindstrom TM and Bennett PR (2005) The role of nuclear factor kappaB in human labour. Reproduction 130 569-581
Lindstrom TM, Mohan AR, Johnson MR and Bennett PR (2008) Histone deacetylase inhibitors exert time-dependent effects on Nuclear Factor-kB but consistently suppress the expression of labour-associated, pro-inflammatory genes in human myometrial cells. Molecular Pharmacology in press
Linette GP, Li Y, Roth K and Korsmeyer SJ (1996) Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation. Proceedings of the National Academy of Sciences USA 93 9545-9552
Ling H and Recklies AD (2004) The chitinase 3-like protein HC-gp39 inhibits cellular responses to the inflammatory cytokines interleukin 1 and tumour necrosis factor-alpha. Biochemical Journal 380 651-659
Ling JH, Chen YQ, Li JB,Pan YZ, Cao Y and Shen DZ (2006) Effects of Jianwei Yuyang granule on inflammatory reaction and NF-kB expression in rat gastric mucosa of ulcer healing and recurrence [Article in Chinese]. Zhongguo Zhong Yao Za Zhi 31 1454-1457
Ling JH, Li JB, Shen DZ and Zhou B (2006) Nuclear factor-kB mRNA and protein expression in stomach tissue of rats with gastric ulcer recurrence and effect of jianwei yuyang granule on its expression [Article in Chinese]. Zhongguo Zhong Xi Yi Jie He Za Zhi 26 228-231
Ling L and Goeddel DV (2000) T6BP, a TRAF6-interacting protein involved in IL-1 signaling. Proceedings of the National Academy of Sciences USA 97 9567-9572
Ling L, Cao Z and Goeddel DV (1998) NF-kB-inducing kinase activates IKK-a by phosphorylation of Ser-176. Proceedings of the National Academy of Sciences USA 95 3792-3797
Ling LJ, Ho FC, Chen YT, Holborow DW, Liu TY and Hung SL (2005) Areca nut extracts modulated expression of alkaline phosphatase and receptor activator of nuclear factor kB ligand in osteoblasts. Journal of Clinical Periodontology 32 353-359
Ling MT, Wang X, Ouyang XS, Xu K, Tsao SW and Wong YC (2003) Id-1 expression promotes cell survival through activation of NF-kB signalling pathway in prostate cancer cells. Oncogene 22 4498-4508
Ling W, Rayman P, Uzzo R, Clark P, Kim HJ, Tubbs R, Novick A, Bukowski R, Hamilton T and Finke J (1998) Impaired activation of NFkB in T cells from a subset of renal cell carcinoma patients is mediated by inhibition of phosphorylation and degradation of the inhibitor, IkBa. Blood 92 1334-1341
Link E, Kerr LD, Schreck R, Zabel U, Verma I and Baeuerle PA (1992) Purified IkB-b is inactivated upon dephosphorylation. Journal of Biological Chemistry 267 239-246
Linker RA, Baeuerle PA and Kaltschmidt C (1996) Cloning of the murine relA (p65 NF-kB) gene and comparison to the human gene reveals a distinct first intron. Gene 176 119-124
Linnell J, Mott R, Field S, Kwiatkowski DP, Ragoussis J and Udalova IA (2004) Quantitative high-throughput analysis of transcription factor binding specificities. Nucleic Acids Research 32 E44
Liotta F, Angeli R, Cosmi L, Fili L, Manuelli C, Frosali F, Mazzinghi B, Maggi L, Pasini A, Lisi V, Santarlasci V, Consoloni L, Angelotti ML, Romagnani P, Parronchi P, Krampera M, Maggi E, Romagnani S and Annunziato F (2007) TLR3 and TLR4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signalling. Stem Cells inpress
Liou H-C (2002) Regulation of the immune system by NF-kB and IkB. Journal of Biochemistry and Molecular Biology 35 537-546
Liou H-C and Baltimore D (1993) Regulation of NF-kB/rel transcription factor and IkB inhibitor system. Current Opinion in Cell Biology 5 477-487
Liou HC and Hsia CY (2003) Distinctions between c-Rel and other NF-kB proteins in immunity and disease. BioEssays 25 767-780
Liou HC, Jin Z, Tumang J, Andjelic S, Smith KA and Liou ML (1999) c-Rel is crucial for lymphocyte proliferation but dispensable for T cell effector function. International Immunology 11 361-371
Liou H-C, Nolan GP, Ghosh S, Fujita T and Baltimore D (1992) The NF-kB p50 precursor, p105, contains an internal IkB-like inhibitor that preferentially inhibits p50. EMBO Journal 11 3003-3009
Liou H-C, Sha WC, Scott ML and Baltimore D (1994) Sequential induction of NF-kB/Rel family proteins during B-cell terminal differentiation. Molecular and Cellular Biology 14 5349-5359
Liou JT, Chen ZY, Ho LJ, Yang SP, Chang DM, Liang CC and Lai JH (2008) Differential effects of triptolide and tetrandrine on activation of COX-2, NF-kB, and AP-1 and virus production in dengue virus-infected human lung cells. European Journal of Pharmacology in press
Liou LS, Sadhukhan PC, Bandyopadhyay SK and Rackley RR (2003) Bacillus of Calmette and Guerin modulates nuclear factor kappa beta in two urothelial carcinoma cell lines. Advances in Experimental and Medical Biology 539 599-621
Liou ML and Liou HC (1999) The ubiquitin-homology protein, DAP-1, associates with tumor necrosis factor receptor (p60) death domain and induces apoptosis. Journal of Biological Chemistry 274 10145-10153
Lipniacki T, Paszek P, Brasier AR, Luxon B and Kimmel M (2004) Mathematical model of NF-kB regulatory module. Journal of Theoretical Biology 228 195-215
Lipniacki T, Paszek P, Brasier AR, Luxon B and Kimmel M (2005) Stochastic regulation in early immune response. Biophysical Journal 90 725-742
Lipniacki T, Puszynski K, Paszek P, Brasier AR and Kimmel M (2007) Single TNFa trimers mediating NF-kB activation: stochastic robustness of NF-kB signaling.BMC Bioinformatics 8 376
Lippert E, Falk W, Bataille F, Kahne T, Naumann M, Goeke M, Herfarth H, Schoelmerich J and Rogler G (2006) Soluble galectin-3 is a strong, colonic epithelial-cell derived, lamina propria fibroblast-stimulating factor. Gut in press
Lipsky RH, Xu K, Zhu D, Kelly C, Terhakopian A, Novelli A and Marini AM (2001) Nuclear factor kB is a critical determinant in N-methyl-D-aspartate receptor-mediated neuroprotection. Journal of Neurochemistry 78 254-264
Liptay S, Bachem M, Hacker G, Adler G, Debatin KM and Schmid RM (1999) Inhibition of nuclear factor kB and induction of apoptosis in T-lymphocytes by sulfasalazine. British Journal of Pharmacology 128 1361-1369
Liptay S, Schmid RM, Nabel EG and Nabel G (1994) Transcriptional regulation of NF-kB2: evidence for kB-mediated positive and negative autoregulation. Molecular and Cellular Biology 14 7695-7703
Liptay S, Schmid RM, Perkins ND, Meltzer P, Altherr MR, McPherson JD, Wasmuth JJ and Nabel G (1992) Related subunits of NF-kB map to two distinct loci associated with translocations in leukemia, NFKB1 and NFKB2. Genomics 13 287-292
Liptay S, Weber CK, Ludwig L, Wagner M, Adler G and Schmid RM (2003) Mitogenic and antiapoptotic role of constitutive NF-kB/Rel activity in pancreatic cancer. International Journal of Cancer 105 735-746
Lipton A, Steger GG, Fiueroa J, Alvarado C, Solal-Celigny P, Body JJ, de Boer R, Beradrdi R, Gascon P, Tonkin KS, Coleman R, Paterson AH, Peterson MC, Fan M, Kinsey A and Jun S (2007) Randomized active-controlled phase II study of denosumab efficacy and safety in patients with breast cancer-related bone metastases. Journal of Clinical Oncology in press
Lisby S, Faurschou A and Gniadecki R (2007) The autocrine TNFalpha signalling loop in keratinocytes requires atypical PKC species and NF-kB activation but is independent of cholesterol-enriched membrane microdomains. BiochemicalPharmacology 73 526-533
Lisowska K and Witkowski JM (2003) Viral strategies in modulation of NF-kB activity. Arch Immunol Ther Exp (Warsz) 51 367-375
Liss AS and Bose Jr HR (2002) Mutational analysis of the v-Rel dimerization interface reveals a critical role for the v-Rel homodimers in transformation. Journal of Virology 76 4928-4939
Litjens NH, Rademaker M, Ravensbergen B, Rea D, Van Der Plas MJ, Thio B, Walding A, Van Dissel JT and Nibbering PH (2004) Monomethylfumarate affects polarization of monocyte-derived dendritic cells resulting in down-regulated Th1 lymphocyte responses. European Journal of Immunology 34 565-575
Littlejohn AF, Tucker SJ, Mohamed AA, McKay S, Helms MJ, Vandenabeele P and MacEwan DJ (2003) Modulation by caspases of tumor necrosis factor-stimulated c-Jun N-terminal kinase activation but not nuclear factor-kB signaling. Biochemical Pharmacology 65 91-99
Liu A, Hoffman PW, Lu W and Bai G (2004) NF-kB site interacts with Sp factors and upregulates the NR1 promoter during neuronal differentiation. Journal of Biological Chemistry 279 17449-17458
Liu AL, Zhang ZM, Zhu BF, Liao ZH and Liu Z (2004) Metallothionein protects bone marrow stromal cells against hydrogen peroxide-induced inhibition of osteoblastic differentiation. Cell Biology International 28 905-911
Liu AM and Wong YH (2004) G16-mediated activation of nuclear factor kB by the adenosine A1 receptor involves c-Src, PKC and ERK signaling. Journal of Biological Chemistry 279 53196-53204
Liu AM and Wong YH (2005) Mu-opioid receptor-mediated phosphorylation of IkB kinase in human neuroblastoma SH-SY5Y cells. Neurosignals 14 136-142
Liu B, Han M and Wen JK (2007) Acetylbritannilactone inhibits neointimal hyperplasia after balloon injury of rat artery by suppressing NF-kB activation.Journal of Pharmacology and Experimental Therapeutics in press
Liu B, Wang S, Brenner M, Paton JF and Kasparov S (2008) Enhancement of cell-specific transgene expression from a Tet-Off regulatory system using a transcriptional amplification strategy in the rat brain. Journal of Gene Medicine in press
Liu B, Yang R, Wong KA, Getman C, Stein N, Teitell MA, Cheng G, Wu H and Shuai K (2005) Negative regulation of NF-kB signaling by PIAS1. Molecular and Cellular Biology 25 1113-1123
Liu B, Yang Y, Chermishof V, Loo RR, Jang H, Tahk S, Yang R, Mink S, Shultz D, Bellone CJ, Loo JA and Shuai K (2007) Proinflammatory stimuli induce IKKa-mediated phosphorylation of PIAS1 to restrict inflammation and immunity. Cell129 903-914
Liu B, Yu SF and Li TJ (2003) Multinucleated giant cells in various forms of giant cell containing lesions of the jaws express features of osteoclasts. Journal of Oral Pathology and Medicine 32 367-375
Liu BH, Yang Y, Paton JF, Li F, Boulaire J, Kasparov S and Wang S (2006) GAL4-NF-kB fusion protein augments transgene expression from neuronal promoters in the rat brain. Molecular Therapy 114 872-882
Liu BG, Jia XM, Cao YY, Chen SH, Gao PH, Wang Y, Jiang YY and Cao YB (2007) Changtai granule, a traditional Chinese drug, protects hapten-induced colitis by attenuating inflammatory and immune dysfunctions. Journal of Ethnopharmacology in press
Liu BR, Hu LH, Guan JM, Liu D and Jiang HC (2007) A study on the apoptosis of gastric carcinoma cells induced by arsenic trioxide combined with Ad-IkappaBalphaM [Article in Chinese]. Zhonghua Nei Ke Za Zhi 46 569-572
Liu C, Sandford G, Fei G and Nicholas J (2004) Galpha protein selectivity determinant specified by a viral chemokine receptor-conserved region in the C tail of the human herpesvirus 8 g protein-coupled receptor. Journal of Virology 78 2456-2467
Liu C, Zhou S, Ke CS, Li NP and Wu RL (2007) Activation and prognostic significance of AKT, NF-kB and STAT3 in breast cancer with lymph node metastasis and estrogen receptor expression [Article in Chinese]. Ai Zheng 26 929-923
Liu CA, Wang CL, Wang FS, Huang HC, Chuang H, Chen RF, Tai FY and Yang KD (2005) Higher spontaneous and TNFa-induced apoptosis of neonatal blood granulocytes. Pediatric Research 58 132-137
Liu CA, Wang MJ, Chi CW, Wu CW and Chen JY (2004) Overexpression of rho effector rhotekin confers increased survival in gastric adenocarcinoma. Journal of Biomedical Science 11 661-670
Liu CP, Kuo YC, Shen CC, Wu MH, Liao JF, Lin YL, Chen CF and Tsai WJ (2007) (S)-Armepavine inhibits human peripheral blood mononuclear cell activation by regulating Itk and PLC{gamma} activation in a PI-3K-dependent manner. Journal ofLeukocyte Biology in press
Liu CA, Wang MJ, Chi CW, Wu CW and Chen JY (2004) Rho/Rhotekin-mediated NF-kB activation confers resistance to apoptosis. Oncogene 23 8731-8742
Lin CI, Chen CN, Huang MT, Lee SJ, Lin CH, CHang CC and Lee H (2008) Lysophosphatidic acid upregulates vascular endothelial growth factor-C and tube formation in human endothelial cells through LPA(1/3), COX-2, and NF-kB activation- and EGFR transactivation-dependent mechanisms. Cellular Signaling in press
Liu CQ, Cao L, Zheng HC, Jia XQ, Kang LM, Li LF and Liu SZ (2006) Expression of nuclear factor-kB and its inhibitor in alveolar macrophages of patients with neonatal hyaline membrane disease [Article in Chinese]. Zhonghua Er Ke Za Zhi 44602-606
Liu CY, Lai YY and Lo CJ (2004) Levamisole modulates prostaglandin E2 production and cyclooxygenase II gene expression in human colonic cancer cells. Journal of Surgical Research 117 223-231
Liu CY, Takemasa A, Liles WC, Goodman RB, Jonas M, Rosen H, Chi E, Winn RK, Harlan JM and Chuang PI (2002) Broad-spectrum caspase inhibition paradoxically augments cell death in TNFa-stimulated neutrophils. Blood 101 295-304
Liu D, Darville M and Eizirik DL (2001) Double-stranded ribonucleic acid (RNA) induces beta-cell Fas messenger RNA expression and increases cytokine-induced beta-cell apoptosis. Endocrinology 142 2593-2599
Liu D, Liu XY, Robinson D, Burnett C, Jackson C, Seele L, Veach RA, Downs S, Collins RD, Ballard DW and Hawiger J (2004) Suppression of staphylococcal enterotoxin B-induced toxicity by a nuclear import inhibitor. Journal of Biological Chemistry 279 19239-19246
Liu D, Xu JK, Figliomeni L, Huang L, Pavlos NJ, Rogers M, Tan A, Price P and Zheng MH (2003) Expression of RANKL and OPG mRNA in periodontal disease: possible involvement in bone destruction. International Journal of Molecular Medicine 11 17-21
Liu D, Zeng BX and Shang Y (2006) Decreased expression of peroxisome proliferator-activated receptor in endotoxin-induced acute lung injury. Physiology Research 55 291-299
Liu D, Zeng BX, Zhang SH and Yao SL (2005) Rosiglitazone, an agonist of peroxisome proliferator-activated receptor gamma, reduces pulmonary inflammatory response in a rat model of endotoxemia. Inflammation Research 54 464-470
Liu D adn Xing M (2008) Potent inhibition of thyroid cancer cells by the MEK inhibitor PD0325901 and its potentiation by suppression of the PI3K and NF-kB pathways. Thyroid in press
Liu DZ, Liang HJ, Chen CH, Su CH, Lee TH, Huang CT, Hou WC, Lin SY, Zhong WB, Lin PJ, Hung LF and Liang YC (2007) Comparative anti-inflammatory characterization of wild fruiting body, liquid-state fermentation, and solid-state culture of Taiwanofungus camphoratus in microglia and the mechanism of its action. Journal of Ethnopharmacology in press
Liu DF, Wei W and Song LH (2006) Upregulation of TNF-a and IL-6 mRNA in mouse liver induced by bacille Calmette-Guerin plus lipopolysaccharide. Acta Pharmacologica Sinica 27 460-468
Liu DY, Li XW, Li H, Li XM and Ye WL (2007) Expression of cyclooxygenase-2 in a mouse macula densa cell lines and signal transduction of NF-kB and AP-1 [Article in Chinese]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 29 78-82
Liu DZ, Liang HJ, Chen CH, Lin SY, Zhong WB, Ho FM, Ho WC, Lo JL, HO YS, Lin PJ, Hung LF and Liang YC (2007) Switch activation of PI-PLC downstream signals in activated macrophages with wortmannin. Biochimica et Biophysica Acta 1773 869-879
Liu E, Law HK and Lau YL (2003) BCG promotes cord blood monocyte-derived dendritic cell maturation with nuclear Rel-B up-regulation and cytosolic IkB alpha and beta degradation. Pediatrics Research 54 105-112
Liu F, Morris S, Epps J and Carroll R (2002) Demonstration of an activation regulated NF-kB/IkBa complex in human platelets. Thrombosis Research 106 199-203
Liu F, Shollenberger LM and Huang L (2004) Non-immunostimulatory nonviral vectors. FASEB Journal 18 1779-1781
Liu FL, Chen CH, Chu SJ, Chen JH, Lai JH, Sytwu HK and Chang DM (2007) Interleukin (IL)-23 p19 expression induced by IL-1beta in human fibroblast-like synoviocytes with rheumatoid arthritis via active nuclear factor-kB and AP-1 dependent pathway. Rheumatology (Oxford) 46 1266-1273
Liu FY, Li Y, Peng YM, Ye K, Li J, Liu YH, Duan SB, Ling GH, Xu XQ and Zhou LT (2008) Norcantharidin ameliorates proteinuria, associated tubulointerstitial inflammation and fibrosis in protein overload nephropathy. American Journal of Nephrology in press
Liu G, Chen N, Kaji A, Bode AM, Ryan CA and Dong Z (2001) Proteinase inhibitors I and II from potatoes block UVB-induced AP-1 activity by regulating the AP-1 protein compositional patterns in JB6 cells. Proceedings of the National Academy of Sciences USA 98 5786-5791
Liu G, Fu AJ, LI JM, Zhu J and Chen T (2005) Dynamic observation of pathological changes and expression of nuclear factor-kB in the intestinal mucosa of rats after diffuse brain injury [Article in Chinese]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 17 555-557
Liu G, Park YJ and Abraham E (2008) Interleukin-1 receptor-associated kinase (IRAK)-1-mediated NF-kB activation requires cytosolic and nuclear activity. FASEB Journal in press
Liu G, Tsuruta Y, Gao Z, Park YJ and Abraham E (2007) Variant IL-1 receptor-associated kinase-1 mediates increased NF-kB activity. Journal of Immunology 179 4125-4134
Liu G, Wang W, Sun G, Ma X, Liu Z and Yang J (2008) Nystatin interferes with the effects of N-methyl-N’-nitro-N-nitrosoguanidine on sphingolipid metabolism in human FL cells. Lipids in press
Liu G, Zhang F, Lee J and Dong Z (2005) Selective induction of interleukin-8 expression in metastatic melanoma cells by transforming growth factor-beta1. Cytokine 31 241-249
Liu GH, Qu J and Shen X (2008) NF-kB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK. Biochimica et Biophysica Acta in press
Liu GH, Wang SR, Wang B and Kong BH (2006) Inhibition of nuclear factor-kB by an antioxidant enhances paclitaxel sensitivity in ovarian carcinoma cell line.Internataional Journal of Gynecology and Cancer 16 1777-1782
Liu GM, Ding XQ, Xu GZ and Wang JK (2003) Effects and mechanisms of endotoxin pretreatment on lung of rat in endotoxemia [Article in Chinese]. Zhonghua Wai Ke Za Zhi 41 856-860
Liu GS, Liu LF, Lin CJ, Tseng JC, Chuang MJ, Lam HC, Lee JK, Yang LC, Chan JH, Howng SL and Tai MH (2006) Gene transfer of pro-opiomelanocortin prohormone suppressed the growth and metastasis of melanoma: involvement of alpha-MSH-mediated inhibition of NFkB/COX-2 pathway. Molecular Pharmacology 69 440-451
Liu GY, Frank N, Bartsch H and Lin JK (1998) Induction of apoptosis by thiuramdisulfides, the reactive metabolites of dithiocarbamates, through coordinate modulation of NFkB, c-fos/c-jun, and p53 proteins. Molecular Carcinogenesis 22 235-244
Liu H, Lee ES, Gajdos C, Pearce ST, Chen B, Osipo C, Loweth J, McKian K, De Los Reyes A, Wing L and Jordan VC (2003) Apoptotic action of 17beta-estradiol in raloxifene-resistant MCF-7 cells in vitro and in vivo. Journal of the National Cancer Institute 95 1586-1597
Liu H and Lee SS (2008) Nuclear factor-kB inhibition improves myocardial contractility in rats with cirrhotic cardiomyopathy. Liver International in press
Liu H, Liu K and Bodenner DL (2005) Estrogen receptor inhibits interleukin-6 gene expression by disruption of nuclear factor kB transactivation. Cytokine 31 251-257
Liu H, Liu ZH, Chen ZH, Yang JW and Li LS (2000) Triptolide: a potent inhibitor of NF-kB in T-lymphocytes. Acta Pharmacol Sin 21 782-786
Liu H, Lo CR, Czaja MJ (2002) NF-kB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-Jun. Hepatology 35 772-778
Liu H, Lo CR, Jones BE, Pradhan Z, Srinivasan A, Valentino KL, Stockert RJ and Czaja MJ (2000) Inhibition of c-myc expression sensitizes hepatocytes to tumor necrosis factor-induced apoptosis and necrosis. Journal of Biological Chemistry 275 40155-40162
Liu H, Ma Y, Pagliari LJ, Perlman H, Yu C, Lin A and Pope RM (2004) TNF-alpha-induced apoptosis of macrophages following inhibition of NF-kB: a central role for disruption of mitochondria. Journal of Immunology 172 1907-1915
Liu H, Perlman H, Pagliari LJ and Pope RM (2001) Constitutively activated Akt-1 is vital for the survival of human monocyte-differentiated macrophages. Role of Mcl-1, independent of nuclear factor (NF)-kB, Bad, or caspase activation. Journal of Experimental Medicine 194 113-126
Liu H, Schwartz MJ, Hwang DH and Scherr DS (2008) Tumour growth inhibition by an imidazoquinoline is associated with c-Myc down-regulation in urothelial cell carcinoma. BJU International in press
Liu H, Sidiropoulos P, Song G, Pagliari LJ, Birrer MJ, Stein B, Anrather J and Pope RM (2000) TNF-a gene expression in macrophages: regulation by NF-kB is independent of c-Jun or C/EBP beta. Journal of Immunology 164 4277-4285
Liu H, Yu W, Liou LY and Rice AP (2003) Isolation and characterization of the human DC-SIGN and DC-SIGNR promoters. Gene 313 149-159
Liu H, Zang C, Fenner MH, Liu D, Possinger K, Koeffler HP and Elstner E (2006) Growth inhibition and apoptosis in human Philadelphia chromosome positive lymphoblastic leukemia cell lines by treatment with the dual PPARalpha/gamma ligand TZD18. Blood 107 3683-3692
Liu H, Zhao SQ, Han DM et al (2007) Correlation between the expression of NF-kB and the T helper cell predominant differentiation in a rat model of otitis media with effusion [Article in Chinese]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 42 699-700
Liu H, Zhao Y, Nie D, SHi J, Fu L, Li Y, Yu D and Lu J (2008) Association of a functional cytochrome P450 4F2 haplotype with urinary 20-HETE and hypertension. Journal of the American Society of Nephrology in press
Liu HB, Cui NQ, Li DH and Chen C (2006) Role of Kupffer cells in acute hemorrhagic necrotizing pancreatitis-associated lung injury of rats. World Journal of Gastroenterology 12 403-407
Liu HB, Cui NQ, Wang Q, Li DH and Xue XP (2008) Sphingosine-1-phosphate and its analogue FTY720 diminish acute pulmonary injury in rats with acute necrotizing pancreatitis. Pancrease 36 e10-e15
Liu HD, Zheng H, Li M, Hu DS, Tang M and Cao Y (2006) Upregulated expression of kappa light chain by Epstein-Barr virus encoded latent membrane protein 1 in nasopharyngeal carcinoma cells via NF-kB and AP-1 pathways. Cellular Signaling in press
Liu HQ, Wei XB, Sun R, Cai YW, Lou HY, Wang JW, Chen AF and Zhang XM (2006) Angiotensin II stimulates intercellular adhesion molecule-1 via an AT(1) receptor/nuclear factor-kB pathway in brain microvascular endothelial cells.Life Sciences 78 1293-1298
Liu HH, Xie M, Schneider MD and Chen ZJ (2006) Essential role of TAK1 in thymocyte development and activation. Proceedings of the National Academy ofSciences USA 103 11677-11682
Liu HJ, Lin PY, Wang LR, Hsu HY, Liao MH and Shih WL (2008) Activation of small GTPases RhoA and Rac1 is required for avian reovirus p10-induced syncytium formation. Mol Cells in press
Liu HS, Pan CE, Liu QG, Yang W and Liu XM (2003) Effect of NF-kB and p38 MAPK in activated monocytes/macrophages on pro-inflammatory cytokines of rats with acute pancreatitis. World Journal of Gastroenterology 9 2513-2518
Liu HX, Zhang RS, Yao XJ, Liu MC, Hu ZD and Fan BT (2003) QSAR study of ethyl 2-[(3-Methyl-2,5-dioxo(3-pyrrolinyl))amino]-4-
(trifluoromethyl) pyrimidine-5-carboxylate: an inhibitor of AP-1 and NF-kB mediated gene expression based on support vector machines. J Chem Inf Comput Sci 43 1288-1296
Liu HP, Wu CC and Chang YS (2006) PRA1 promotes the intracellular trafficking and NF-kB signaling of EBV latent membrane protein 1. EMBO Journal 25 4120-4130
Liu HZ, Gong JP, Wu CX, Peng Y, Li XH and You HB (2005) The U937 cell line induced to express CD14 protein by 1,25-dihydroxyvitamin D3 and be sensitive to endotoxin stimulation. Hepatobiliary Pancreat Dis Int 4 84-89
Liu J and Beller D (2002) Aberrant production of IL-12 by macrophages from several autoimmune-prone mouse strains is characterized by intrinsic and unique patterns of NF-kB expression and binding to the IL-12 p40 promoter. Journal of Immunology 169 581-586
Liu J and Beller DI (2003) Distinct pathways for NF-kB regulation are associated with aberrant macrophage IL-12 production in lupus- and diabetes-prone mouse strains. Journal of Immunology 170 4489-4496
Liu J, Cao S, Herman LM and Ma X (2003) Differential regulation of interleukin (IL)-12 p35 and p40 gene expression and interferon (IFN)-{gamma}-primed IL-12 production by IFN regulatory factor 1. Journal of Experimental Medicine 198 1265-1276
Liu J, Feng X, Yu M, Xie W, Zhao X, Li W, Guan R and Xu J (2007) Pentoxifylline attenuates the development of hyperalgesia in a rat model of neuropathic pain.Neuroscience Letters 412 268-272
Liu J, Jin DZ, Xiao L and Zhu XZ (2006) Paeoniflorin attenuates chronic cerebral hypoperfusion-induced learning dysfunction and brain damage in rats. Brain Research 1089 162-170
Liu J, Fan QR, Sodeoka M, Lane WS and Verdine GL (1994) DNA binding by an amino acid residue in the C-terminal half of the Rel homology region. Chemistry and Biology 1 47-55
Liu J, Guan X and Ma X (2007) Regulation of IL-27 p28 gene expression in macrophages through MyD88- and interferon-gamma-mediated pathways. Journal of Experimental Medicine 204 141-152
Liu J, Kadiiska MB, Liu Y, Lu T, Qu W and Waalkes MP (2001) Stress-related gene expression in mice treated with inorganic arsenicals. Toxicological Sciences 61 314-320
Liu J, Kumar KGS, Yu D, Molton SA, McMahon M, Herlyn M, Thomas-Tikhonenko A and Fuchs SY (2007) Oncogenic BRAF regulates beta-Trcp expression and NF-kB activity in human melanoma cells. Oncogene 26 1954-1958
Liu J, Liao H, Zhang Y and Liu L (2006) Regulation of the expression of interleukin-4 and interleukin-5 by the signal pathway of PKC-NF-kB in T lymphocyte of allergic rhinitis [Article in Chinese]. Lin Chuang Er Bi Yan Hou Ke Za Zhi 20 197-200
Liu J and Lin A (2005) Role of JNK activation in apoptosis: A double-edged sword. Cell Research 15 36-42
Liu J and Lin A (2007) Wiring the cell signaling circuitry by the NF-kB and JNK1 crosstalk and its applications in human diseases. Oncogene 26 3267-3278
Liu J and Ma X (2006) Interferon regulatory factor 8 regulates RANTES gene transcription in cooperation with interferon regulatory factor-1, NF-kB and PU.1. Journal of Biological Chemistry 281 19188-19195
Liu J, Narasimhan P, Yu F and Chan PH (2005) Neuroprotection by hypoxic preconditioning involves oxidative stress-mediated expression of hypoxia-inducible factor and erythropoietin. Stroke 36 1264-1269
Liu J, Perkins ND, Schmid RM and Nabel GJ (1992) Specific NF-kB subunits act in concert with Tat to stimulate human immunodeficiency virus type 1 transcription. Journal of Virology 66 3883-3887
Liu J, Qu W, Saavedra JE and Waalkes MP (2004) The nitric oxide donor, V-Pyrro/NO, protects against cadmium-induced hepatotoxicity in mice. Journal of Pharmacology and Experimental Therapy 3 709-714
Liu J, Saavedra JE, Lu T, Song JG, Clark J, Waalkes MP and Keefer LK (2001) O(2)-Vinyl 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate protection against D-galactosamine/endotoxin-induced hepatotoxicity in mice: genomic analysis using microarrays. Journal of Pharmacology and Experimental Therapeutics 300 18-25
Liu J, Sodeoka M, Lane WS and Verdine GL (1994) Evidence for a non-a-helical DNA-binding motif in the Rel homology region. Proceedings of the National Academy of Sciences USA 91 908-912
Liu J, Tang D, Minemoto Y, Leitges M, Rosner MR and Lin A (2006) NF-kB is required for UV-induced JNK activation via induction of PKCdelta. Molecular Cell21 467-480
Liu J, Wang ZT, Ji LL and Ge BX (2007) Inhibitory effects of neoandrographolide on nitric oxide and prostaglandin E(2) production in LPS-stimulated murine macrophage. Molecular and Cellular Biochemistry in press
Liu J, Xu K, Wen G, Guo H, Li S, Wu X, Dai R, Sheng Z and Liao E (2008) Comparison of the effects of genistein and zoledronic acid on the bone loss in OPG-deficient mice. Bone in press
Liu J, Yang G, Thompson-Lanza JA, Glassman A, Hayes K, Patterson A, Marquez RT, Auersperg N, Yu Y, Hahn WC, Mills GB and Bast RC Jr (2004) A genetically defined model for human ovarian cancer. Cancer Research 64 1655-1663
Liu J, Yoshida Y and Yamashita U (2007) Suppressive effect of reactive oxygen species on CD40-induced B cell activation.
FEBS Letters in press
Liu J, Yoshida Y and Yamashita U (2008) DNA-binding activity of NF-kB and phosphorylation of p65 are induced by N-acetylcysteine through phosphatidylinositol (PI) 3-kinase. Molecular Immunology in press
Liu J, Zhan M, Hannay JA, Das P, Bolshakov SV, Kotilingam D, Yu D, Lazar AF, Pollock RE and Lev D (2006) Wild-type p53 inhibits nuclear factor-kB-induced matrix metalloproteinase-9 promoter activation: implications for soft tissue sarcoma growth and metastasis. Molecular Cancer Research 4 803-810
Liu J, Zou L, Zheng Y, Liu T, Luo S and Zhao Z (2006) NF-kB is involved in early cellular response to mechanical stimuli in osteoblast-like cells in vitro.Biochemical and Biophysical Research Communications in press [WITHSDRAWN]
Liu J, Zou L, Zheng Y, Zhao Z,, Li Y, Yang P and Luo S (2007) NF-kB responds to mechanical strains in osteoblast-like cells, and lighter strains create an NF-kB response more readily.
Cell Biology International in press
Liu JC, He M, Wan L and Cheng XS (2007) Heat shock protein 70 gene transfection protects rat myocardium cell against anoxia-reoxygeneration injury. ChineseMedical Journal (English) 120 578-583
Liu JC, Cheng TH, Lee HM, Lee WS, Shih NL, Chen YL, Chen JJ and Chan P (2004) Inhibitory effect of trilinolein on angiotensin II-induced cardiomyocyte hypertrophy. European Journal of Pharmacology 484 1-8
Liu JF, Jamieson GG, Drew PA, Zhu GJ, Zhang SW, Zhu TN, Shan BE and Wang QZ (2005) Aspirin induces apoptosis in oesophageal cancer cells by inhibiting the pathway of NF-kB downstream regulation of cyclooxygenase-2. ANZ Journal ofSurgery 75 1011-1016
Liu JF, Zhang SW, Jamieson GG, Zhu GJ, Wu TC, Zhu TN, Shan BE adn Drew PA (2007) The effects of a COX-2 inhibitor meloxicam on squamous cell carcinoma of the esophagus in vivo. International Journal of Cancer in press
Liu JJ, Hou SC and Shen CK (2003) Erythroid gene suppression by NF-kB. Journal of Biological Chemistry 278 19534-19540
Liu JL, Chiles TC, Sen RJ and Rothstein TL (1991) Inducible nuclear expression of NF-kB in primary B cells stimulated through the surface Ig receptor. Journal of Immunology 146 1685-1691
Liu JL, Sen R and Rothstein TL (1993) Abnormal kB-binding protein in the cytoplasm of a plasmacytoma cell line that lacks nuclear expression of NF-kB. Molecular Immunology 30 479-489
Liu JO (2005) The yins of T cell activation. Science STKE 265:re1
Liu JX, Han X and Ma XB (2005) Effect of Shuangshen Tongguan recipe on nuclear factor-kaB signal pathway and myocardial junction-mediated intercellular communication in acute myocardial ischemia/reperfusion injured model rats [Article in Chinese]. Zhongguo Zhong Xi Yi Jie He Za Zhi 25 228-231
Liu K, Chi DS, Li C, Hall HK, Milhorn DM and Krishnaswamy G (2005) HIV-1 Tat protein-induced VCAM-1 expression in human pulmonary artery endothelial cells and its signaling. American Journal of Physiology: Lung Cell and Molecular Physiology 289 L252-L260
Liu KL, Chen HW, Wang RY, Lei YP, Sheen LY and Lii CK (2006) DATS reduces LPS-induced iNOS expression, NO production, oxidative stress, and NF-kB activation in RAW 264.7 macrophages.
Journal of Agriculature and Food Chemistry 54 3472-3478
Liu L and Papaconstantinou J (1995) The effect of aging on RelB levels in mouse liver and spleen. Abstract of the American Society for Cell Biology, Molecular Biology of the Cell 94a 550
Liu L and D’Mello SR (2005) Phosphorylation of IkB-beta is necessary for neuronal survival. Journal of Biological Chemistry in press
Liu L, Eby MT, Rathore N, Sinha SK, Kumar A and Chaudhary PM (2002) The human herpes virus 8 encoded viral FLICE inhibitory protein physically associates with and persistently activates the IkB kinase complex. Journal of Biological Chemistry 277 13745-13751
Liu L, Ji C, Chen J, Li Y, Fu X, Xie Y, Gu S and Mao Y (20080 A global genomic view of MIF knockdown-mediated cell cycle arrest. Cell Cycle in press
Liu L, Ning ZQ, Shan S, Zhang K, Deng T, Lu XP and Cheng YY (2005) Title. Planta Med 71 808-813
Liu L, Kwak Y-T, Bex F, García-Martínez LF, Li X-H, Meek K, Lane WS and Gaynor RB (1998) DNA-dependent protein kinase phosphorylation of IkBa and IkBb regulates NF-kB DNA binding properties. Molecular and Cellular Biology 18 4221-4234
Liu L, Paul A, MacKenzie CJ, Bryant C, Graham A and Plevin R (2002 Nuclear factor kB is involved in lipopolysaccharide-stimulated induction of interferon regulatory factor-1 and GAS/GAF DNA-binding in human umbilical vein endothelial cells. British Journal of Pharmacology 134 1629-1638
Liu L, Sakai T, Sano N and Fukui K (2004) Nucling mediates apoptosis by inhibiting expression of galectin-3 through interference with NF-kB signaling. Biochemical Journal 380 31-41
Liu LH, Ren WJ, Wang GZ, Qin ZX, Wang XM, Wu SY, Liu Y and Liu LM (2006) Effects and significance of gas explosion on expression of NF-kB and ICAM1 in lung tissue of rats [Article in Chinese]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing ZaZhi 24 409-411
Liu LP, Xia YF, Yang L, DiDonato JA, DiCorleto PE, Zhong CP and Geng JG (2001) B lymphocytes and plasma cells express functional E-selectin by constitutive activation of NF-kB. Biochemical and Biophysical Research Communications 286 281-291
Liu LY, Bates ME, Jarjour NN, Busse WW, Bertics PJ and Kelly EA (2007) Generation of Th1 and Th2 chemokines by human eosinophils: evidence for a critical role of TNF-a. Journal of Immunology. 179 4840-4848
Liu M, Kluger MS, D’Alessio A, Garcia-Cardena G and Pober JS (2008) Regulation of arterial-venous differences in tumor necrosis factor responsiveness of endothelial cells by anatomic context. American Journal of Pathology in press
Liu M and Vakharia VN (2006) Nonstructural protein of infectious bursal disease virus inhibits apoptosis at the early stage of virus infection. Journal ofVirology 80 3369-3377
Liu M, Yang Y, Gu C, Yue Y, Wu KK, Wu J and Zhu Y (2007) Spike protein of SARS-CoV stimulates cyclooxygenase-2 expression via both calcium-dependent and calcium-independent protein kinase C pathways. FASEB Journal in press
Liu MT, Chang YT, Chen SC, Chuang YC, Chen YR, Lin CS and Chen JY (2005) Epstein-Barr virus latent membrane protein 1 represses p53-mediated DNA repair and transcriptional activity. Oncogene 24 2635-2646
Liu N, Duan TD and Zheng N (2006) Effects of TGF-beta1, gene modified donor dendritic cells on immune repulsion [Article in Chinese]. Sichuan Da Xue Xue Bao Yi Xue Ban 37 721-725
Liu N, Phillips T, Zhang M, Wang Y, Opferman JT, Shah R and Ashton-Rickardt PG (2004) Serine protease inhibitor 2A is a protective factor for memory T cell development. Nature Immunology 5 919-926
Liu N, Raja SM, Zazzeroni F, Metkar SS, Shah R, Zhang M, Wang Y, Bromme D, Russin WA, Lee JC, Peter ME, Froelich CJ, Franzoso G and Ashton-Rickardt PG (2003) NF-kB protects from the lysosomal pathway of cell death. EMBO Journal 22 5313-5322
Liu N, Zhang J, Zhang J, Liu S, Liu Y and Zheng D (2008) Erbin regulated sensitivity of MCF-7 breast cancer cells to TRAIL via ErbB2/AKT/NF-kB pathway. Journal of Biochemistry in press
Liu P, Jamaluddin M, Li K, Garofalo RP, Casola A and Brasier AR (2006) Retinoic acid inducible gene-I mediates early anti-viral response and Toll like receptor 3 expression in respiratory syncytial virus-infected airway epithelial cells.Journal of Virology in press
Liu P, Li K, Gaarofalo RP and Brasier AR (2008) RSV-induces RelA release from cytoplasmic 100 kDa NF-kB2 complexes via a novel retinoic acid inducible gene-I-NF-kB inducing kinase (NIK) signaling pathway. Journal of Biological Chemistry in press
Liu PP, Le J and Nian M (2001) Nuclear factor-kB decoy: infiltrating the heart of the matter in inflammatory heart disease. Circulation Research 89 850-852
Liu Q, Chen T, Chen G, Li N, Wang J, Ma P and Cao X (2006) Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-kB activation. Biochemical and Biophysical Research Communications 345 1122-1130
Liu Z, Chen T, Chen G, Shu X, Sun A, Ma P, Lu L and Cao X (2007) Triptolide impairs dendritic cell migration by inhibiting CCR7 and COX-2 expression through PI3-K/Akt and NF-kB pathways. Molecular Immunology 44 2686-2696
Liu Q, Fan J, McMahon M, Prince AM and Zhang P (2001) Role of the oncogenic Raf-1 in orchestration of discrete nuclear factor-kB-activating pathways. Molecular and Cell Biology Research Communications 4 381-389
Liu Q, Inoue H and Mahendran R (2008) Transcriptional regulation of the COX-2 expression by nitric oxide in colon cancer cell lines. Oncology Reports 19 269-274
Liu Q, Shu X, Sun A, Sun Q, Zhang C, An H, Liu J and Cao X (2008) Plant-derived small molecule albaconol suppresses LPS-triggered proinflammatory cytokine production and antigen presentation of dendritic cells by impairing NF-kB activation. International Immunopharmacology 8 1103-1111
Liu Q, White LR, Clark SA, Heffner DJ, Winston BW, Tibbles LA and Muruve DA (2005) Akt/protein kinase B activation by adenovirus vectors contributes to NFkB-dependent CXCL10 expression. Journal of Virology 79 14507-14515
Liu Q, Zhang J, Zhu H, Qin C, Chen Q and Zhao B (2006) Dissecting the signaling pathway of nicotine-mediated neuroprotection in a mouse Alzheimer disease model.FASEB Journal 21 61-73
Liu QC, Fang Y, Li XY, Liang WJ and Zeng YX (2003) Cloning of NP9 gene and its influence on cyclin D1 transcription activity [Article in Chinese]. Ai Zheng 22 725-728
Liu QP, Fruit K, Ward J and Correll PH (1999) Negative regulation of macrophage activation in response to IFN-gamma and lipopolysaccharide by the STK/RON receptor tyrosine kinase. Journal of Immunology 163 6606-6613
Liu R, O’Connell M, Johnson K, Pritzker K, Mackman N and Terkeltaub R (2000) Extracellular signal-regulated kinase 1/extracellular signal-regulated kinase 2 mitogen-activated protein kinase signaling and activation of activator protein 1 and nuclear factor kB transcription factors play central roles in interleukin-8 expression stimulated by monosodium urate monohydrate and calcium pyrophosphate crystals in monocytic cells. Arthritis Rheum 43 1145-1155
Liu R, Zhao X, Gurney TA and Landau NR (1998) Functional analysis of the proximal CCR5 promoter. AIDS Research and Human Retroviruses 14 1509-1519
Liu RY, Fan C, Liu G, Olashaw NE and Zuckerman KS (2000) Activation of p38 mitogen-activated protein kinase is required for tumor necrosis factor-a-supported proliferation of leukemia and lymphoma cell lines. Journal of Biological Chemistry 275 21086-21093
Liu RY, Fan C, Olashaw NE, Wang X and Zuckerman KS (1999) Tumor necrosis factor-a-induced proliferation of human Mo7e leukemic cells occurs via activation of nuclear factor kB transcription factor. Journal of Biological Chemistry 274 13877-13885
Liu RY, Fan C, Olashaw NE, Wang X and Zuckerman KS (1999) Tumor necrosis factor-a-induced proliferation of human Mo7e leukemic cells occurs via activation of nuclear factor kB transcription factor. Journal of Biological Chemistry 274 13877-13885
Liu S, Feng G, Wang GL and Liu GJ (2008) p38MAPK inhibition attenuates LPS-induced acute lung injury involvement of NF-kB pathway. European Journal of Pharmacology 584 158-165
Liu S, Ishikawa H, Li FJ, Ma Z, Otsuyama K, Asaoku H, Abroun S, Zheng X, Tsuyama N, Obata M and Kawano MM (2005) Dehydroepiandrosterone can inhibit the proliferation of myeloma cells and the interleukin-6 production of bone marrow mononuclear cells from patients with myeloma. Cancer Research 65 2269-2276
Liu S, Liu Z, Xie Z, Pang J, Yu J, Lehmann E, Huynh L, Vukosaljevic T, Takeki M, Klisovic RB, Baiocchi RA, Blum W, Porcu P, Garzon R, Byrd JC, Perrotti D, Caligiuri MA, Chang KK, Wu LC and Marcucci G (2007) Bortezomib induces DNA hypomethylation and silenced gene transcription by interfering with Sp1/NF-kB-dependent DNA methyltransferase activity in acute myeloid leukemia. Blood 111 2364-2373
Liu S, Tan WY, Chen QR, Chen XP, Fu K, Zhao YY and Chen ZQ (2008) Daintain/AIF-1 promotes breast cancer proliferation via activation of the NF-kB/cyclin D1 pathway and facilitates tumor growth. Cancer Science 99 952-957
Liu SF and Malik AB (2006) NF-kB activation as a pathological mechanism of septic shock and inflammation. American Journal of Physiology: Lung Cell and Molecular Physiology 290 L622-L645
Liu SF, Wang H, Li ZJ, Deng XY, Xiang H, Tao YG, Li W, Tang M and Cao Y (2008) Aspirin induces lytic cytotoxicity in Epstein-Barr virus-positive cells. European Journal of Pharmacology in press
Liu SF, Wang H, Lin XC, Xiang H, Deng XY, Li W, Tang M and Cao Y (2008) NF-kB inhibitors induce lytic cytotoxicity in Epstein-Barr virus-positive nasopharyngeal carcinoma cells. Cell Biology International in press
Liu SF, Ye X and Malik AB (1999) Inhibition of NF-kB activation by pyrrolidine dithiocarbamate prevents In vivo expression of proinflammatory genes. Circulation 100 1330-1337
Liu SF, Ye X and Malik AB (1999) Pyrrolidine dithiocarbamate prevents I-kB degradation and reduces microvascular injury induced by lipopolysaccharide in multiple organs. Molecular Pharmacology 55 658-667
Liu SJ, Zhou SW and Xue CS (2001) Effect of tetrandrine on neutrophilic recruitment response to brain ischemia/reperfusion. Acta Pharmacol Sin 22 971-975
Liu SQ, Yu JP, CHen HL, Luo HS, Chen SM and Yu HG (2006) Therapeutic effects and molecular mechanisms of ginkgo biloba extract on liver fibrosis in rats.American Journal of Chinese Medicine 34 99-114
Liu SQ, Yu JP, He L, Yu HG and Luo HS (2005) Effects of nuclear factor kB and transforming growth factor b1 in the anti-liver fibrosis process using Ginkgo biloba extract [Article in Chinese]. Zhonghua Gan Zang Bing Za Zhi 13 903-907
Liu TG, Yin JQ, Shang BY, Min Z, He HW, Jiang JM, Chen F, Zhen YS and Shao RG (2004) Silencing of hdm2 oncogene by siRNA inhibits p53-dependent human breast cancer. Cancer Gene Therapy 11 748-756
Liu TL, Shimada H, Ochiai T, SHiratori T, Lin SE, Kitagawa M, Karigaya K, Maki M, Oka M, Abe T, Takiguchi M and Hiwasa T (2006) Enhancement of chemosensitivity toward peplomycin calpastatin-stabilized NF-kB p65 in esophogeal carcinoma cells: possible involvemnt of the Fas/Fas-L synergism. Apoptosis in press
Liu TZ, Hu CC, Chen YH, Stern A and Cheng JT (2000) Differentiation status modulates transcription factor NF-kB activity in unstimulated human hepatocellular carcinoma cell lines. Cancer Letters 151 49-56
Liu TZ, Lee KT, Chern CL, Cheng JT, Stern A and Tsai LY (2001) Free radical-triggered hepatic injury of experimental obstructive jaundice of rats involves overproduction of proinflammatory cytokines and enhanced activation of nuclear factor kB. Annals of Clinical Laboratory Science 31 383-390
Liu W, Feng W, Wang F, Li W, Gao C, Zhou B and Ma M (2008) Osteoprotegerin/RANK/RANKL axis in cardiac remodeling due to immuno-inflammatory myocardial disease. Experimental and Molecular Pathology in press
Liu W, Liu Y and Lowe Jr WL (2001) The role of phosphatidylinositol 3-kinase and the mitogen-activated protein kinases in insulin-like growth factor-I-mediated effects in vascular endothelial cells. Endocrinology 142 1710-1719
Liu W, Parikh AA, Stoeltzing O, Fan F, McCarty MF, Wey J, Hicklin DJ and Ellis LM (2005) Upregulation of neuropilin-1 by basic fibroblast growth factor enhances vascular smooth muscle cell migration in response to VEGF. Cytokine in press
Liu W, Reinmuth N, Stoeltzing O, Parikh AA, Tellez C, Williams S, Jung YD, Fan F, Takeda A, Akagi M, Bar-Eli M, Gallick GE and Ellis LM (2003) Cyclooxygenase-2 is up-regulated by interleukin-1beta in human colorectal cancer cells via multiple signaling pathways. Cancer Research 63 3632-3636
Liu W, Wang S, Wei S, Sun L and Feng X (2005) Receptor activator of NF-kB (RANK) cytoplasmic motif, PFQEP369-373, plays a predominant role in osteoclast survival in part by activating Akt/PKB and its downstream effector AFX/FOXO4. Journal of Biological Chemistry 280 43064-43072
Liu W, Xu D, Yang H, Xu H, Shi Z, Cao X, Takeshita S, Liu J, Teale M and Feng X (2004) Functional identification of three RANK cytoplasmic motifs mediating osteoclast differentiation and function. Journal of Biological Chemistry 279 54759-54769
Liu WC, Chuaang WL, Tsai ML, Hong JH, McBride WH and Chaing CS (2008) Cordyceps sinensis health supplement enhances recovery from Taxol-induced leukopenia. Experimental Biology and Medicine (Maywood) 233 447-455
Liu WF, Yu SS and Li YZ (2005) NF-kB tumorigenesis and drug developement [Article in Chinese]. Sheng Wu Gong Cheng Xue Bao 21 12-18
Liu WG, Chen Y, Li B, Lu GQ and Chen SD (2004) Neuroprotection by pergolide against levodopa-induced cytotoxicity of neural stem cells. Neurochemistry Research 29 2207-2214
Liu WK, Chien CY, Chou CK and Su JY (2003) An LKB1-interacting protein negatively regulates TNFa-induced NF-kB activation. Journal of Biomedical Science 10 242-252
Liu WK, Yen PF, Chien CY, Fann MJ, Su JY and Chou CK (2003) ABIN-2 disrupts the interaction of RIP with IKKg to block NF-kB activation and potentiate apoptosis. Biochemical Journal 378 867-876
Liu WM, Strauss SJ, Chaplin T, Shahin S, Propper DJ, Young BD, Joel SP and Malpas JS (2004) s-Thalidomide has a greater effect on apoptosis than angiogenesis in a multiple myeloma cell line. Hematology Journal 5 247-254
Liu X, Buffington JA and Tjalkens RB (2005) NF-kB-dependent production of nitric oxide by astrocytes mediates apoptosis in differentiated PC12 neurons following exposure to manganese and cytokines. Brain Research Molecular Brain Research 141 39-47
Liu X, Jana M, Dasgupta S, Koka S, He J, Wood C and Pahan K (2002) Human immunodeficiency virus type-1 (HIV-1) Tat induces nitric oxide synthase in human astroglia. Journal of Biological Chemistry 277 39312-39319
Liu X, Xie W, Liu P, Duan M, Jia Z, Li W and Xu J (2006) Mechanism of the cardioprotection of rhEPO pretreatment on suppressing the inflammatory response in ischemia-reperfusion.
Life Sciences 78 2255-2264
Liu X, Ye L, Christianson GJ, Yang JQ, Roopernian DC and Zhu X (2007) NF-kB signaling regulates functional expression of the MHC class I-related neonatal Fc receptor for IgG via intronic binding sequences. Journal of Immunology 179 2999-3011
Liu X, Zou S and Qiu F (2002) Expression of nuclear factor kB in hepatitis C virus core gene transfected cholangiocarcinoma cells. Chinese Medical Journal 115 998-1001
Liu XM, Wang Z and Li CS (2006) Viral transactivation of transcription by NF-kB in steroid-responsive simple nephrotic syndrome [Article in Chinese]. Sichuan Da Xue Xue Bao Yi Xue Ban 37 183-186
Liu XY, Shen ZY and Huang JH (2006) Mechanism of epimedium flavonoids in regulating immuno-senescence via nuclear factor-kB related signal transduction pathway [Article in Chinese]. Zhongguo Zhong Xi Yi Jie He Za Zhi 26 620-624
Liu XY, Shen ZY, Wu B, Xia SJ, Huang JH, Chen WH and Ying J (2008) Study on changes of protein phosphorylation of p65, IkBa and IkappaBepsilon in lymphocytes of rats in progress of aging and interventional effect of Epimedium flavonoids [Article in Chinese]. Zhongguo Zhaong Yao Za Zhi 33 73-76
Liu Y, Barua M, Serban V and Quinn MR (2003) Production of inflammatory mediators by activated C6 cells is attenuated by taurine chloramine inhibition of NF-kB activation. Advances in Experimental Medicine 526 365-372
Liu Y, Denlinger CE, Rundall BK, Smith PW and Jones DR (2006) SAHA induces Akt-mediated phosphorylation of p300 which promotes acetylation and transcriptional activation of RelA/p65. Journal of Biological Chemistry in press
Liu Y, Nakahara T,Miyakoshi J, Hu DL, Nakane A and Abe Y (2006) Nuclear accumulation and activation of nuclear factor kB after split-dose irradiation in LS174T cells. Journal of Radiation Research (Tokyo) in press
Liu Y and Quinn MR (2002) Chemokine production by rat alveolar macrophages is inhibited by taurine chloramine. Immunology Letters 80 27-32
Liu Y, Graham C, Li A, Fisher RJ and Shaw S (2002) Phosphorylation of the protein kinase C-theta activation loop and hydrophobic motif regulates its kinase activity, but only activation loop phosphorylation is critical to in vivo nuclear-factor-kB induction. Biochemical Journal 361 255-265
Liu Y, Kimura K, Yanai R, Chikama T and Nishida T (2008) Cytokine, chemokine, and adhesion molecule expression mediated by MAPKs in human corneal fibroblasts exposed to poly(I:C). Investigative Opthalmology and Visual Sciences i49 3336-3344
Liu Y, Mo JQ, Hu Q, Boivin G, Levin L, Lu S, Yang D, Dong Z, Lu S (2008) Targeted overexpression of vav3 oncogene in prostatic epithelium induces nonbacterial prostatitis and prostate cancer. Cancer Research 68 6396-6406
Liu Y, Smith PW and Jones DR (2006) Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing HDAC1-mediated deacetylation of RelA/p65 and promoting apoptosis. Molecular and Cellular Biology in press
Liu Y, Sweet DT, Irani-Tehrani M, Maeda N and Tzima E (2008) Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation. Journal of Cell Biology in press
Liu Y, Tergaonkar V, Krishna S and Androphy EJ (1999) Human papillomavirus type 16 E6-enhanced susceptibility of L929 cells to tumor necrosis factor alpha correlates with increased accumulation of reactive oxygen species. Journal of Biological Chemistry 274 24819-24827
Liu Y, Vincenti MP and Yokata H (2005) Principal component analysis for predicting transcription-factor binding motifs from array-derived data. BMC Bioinformatics in press
Liu Y, Wang Y, Yamakuchi M, Isowaki S, Nagata E, Kanmura Y, Kitajima I andMaruyama I (2001) Upregulation of toll-like receptor 2 gene expression in macrophage response to peptidoglycan and high concentration of lipopolysaccharide is involved in NF-kB activation. Infection and Immunity 69 2788-2796
Liu Y, Wang Y, Yamakuchi M, Masuda S, Tokioka T, Yamaoka S, Maruyama I and Kitajima I (2001) Phosphoinositide-3 kinase-PKB/Akt pathway activation is involved in fibroblast Rat-1 transformation by human T-cell leukemia virus type I tax. Oncogene 20 2514-2526
Liu Y, Wu WK, Chen C and Liu KX (2005) Role of NF-kB in the induction of delayed preconditioning in rat heart by pretreatment with Sini decoction [Article in Chinese]. Zhongguo Zhong Yao Za Zhi 30 453-456
Liu Y, Yan F, Liu Y, Zhang C, Yu H, Zhang Y and Zhao Y (2008) Aqueous extract of rhubarb stabilizes vulnerable atherosclerotic plaques due to depression of inflammation and lipid accumulation. Phytotherapy Research in press
Liu Y and Yokota H (2006) Artificial ants deposit pheromone to search for regulatory DNA elements. BMC Genomics 7 221
Liu Y, Yu H, Zhang Y and Zhao Y (2007) TLRs are important inflammatory factors in atherosclerosis and may be a therapeutic target. Medical Hypotheses in press
Liu Y, Zhang J, Zhao Z and Ling Y (2003) Pro-apoptotic role of NF-kB pathway inhibition in lipopolysaccharide-stimulated polymorphonuclear neutrophils. Chinese Medical Journal (English) 116 1257-1261
Liu Y, Zhu Y, Rannou F, Lee TS, Formentin K, Zeng L, Yuan X, Wang N, Chien S, Forman BM and Shyy JY (2004) Laminar flow activates peroxisome proliferator-activated receptor-{gamma} in vascular endothelial cells. Circulation 110 1128-1133
Liu YC, Hsieh CW, Weng YC, Chuang SH, Hsieh CY and Wung BS (2008) Sulforaphane inhibition of monocyte adhesion via the suppression of ICAM-1 and NF-kB is dependent upon glutathione depletion in endothelial cells. Vascular Pharmacology in press
Liu YC, Hsieh CW, Wu CC and Wung BS (2007) Chalcone inhibits the activation of NF-kB and STAT3 in endothelial cells via endogenous electrophile. Life Sciences80 1420-1430
Liu YL, Zhou LJ, Hu NW, Xu JT, Wu CY, Zhang T, Li YY and Liu XG (2007) Tumor necrosis factor-alpha induces long-term potentiation of C-fiber evoked field potentials in spinal dorsal horn in rats with nerve injury: The role of NF-kB, JNK and p38 MAPK. Neuropharmacology 52 708-715
Liu YP, Wen JK, Zheng B, Zhang DQ and Han M (2007) Acetylbritannilactone suppresses lipopolysaccharide-induced vascular smooth muscle cell inflammatory response.
European Journal of Pharmacology in press
Liu YQ, You S, Tashiro SI, Onodera S and Ikejima T (2006) Roles of Ras and extracellular signal-regulated kinase-dependent IkBa degradation in oridonin-enhanced phagocytosis of apoptotic cells by human macrophage-like U937 cells.International Immunopharmacology 6 260-268
Liu YW, Chen CC, Tseng HP and Chang WC (2006) Lipopolysaccharide-induced transcriptional activation of interleukin-10 is mediated by MAPK- and NF-kB-induced CCAAT/enhancer-binding protein delta in mouse macrophages. CellularSignaling 18 1492-1500
Liu YW, Chen CC, Wang JM, Chang WC, Huang YC, Chung SY, Chen BK and Hung JJ (2007) Role of transcriptional factors Sp1, c-Rel, and c-Jun in LPS-induced C/EBPdelta gene expression of mouse macrophages. Cell and Molecular Life Sciences in press
Liu YX, Cao WS, Irani K and Li XJ (2003) Establishment of a T-Ag and NF-kB binding elements gene co-transfected stable HUVECs cell line. Journal of Cellular Biochemistry 89 1285-1290
Liu YY, Cai WF, Yang HZ, Cui B, Chen ZR, Liu HZ, Yan J, Jin W, Yang HM, Xin BM, Yuan B, Hua F, Hu ZW (2008) Bacillus Calmette-Guerin and TLR4 agonist prevent cardiovascular hypertrophy and ribrosis by regulating immune microenvironment. Journal of Immunology 180 7349-7357
Liu YY, Leboeuf C, Shi JY, Li JM, Wang L, Shen Y, Garcia JF, Shen ZX, Chen Z, Janin A, Chen SJ and Zhao WL (2007) Rituximab plus CHOP (R-CHOP) overcomes PRDM1-associated resistance to chemotherapy in patients with diffuse large B-cell lymphoma.
Blood 110 339-344
Liu Z (2007) The renin-angiotensin system and insulin resistance. Current Diabetes Reports 7 34-42
Liu Z, Fan Y, Wang Y, Han C, Pan Y, Huang H, Ye Y, Luo L and Yin Z (2008) Dipyrithione inhibits lipopolysaccharide-induced iNOS and COX-2 up-regulation in macrophages and protects against endotoxic shock in mice. FEBS Letters in press
Liu Z, Gao F and Tian Y (2006) Effects of morphine, fentanyl and tramadol on human immune response. J Huazhong Univ Sci Technolog Med Sci 26 478-481
Liu Z and Garrard WT (2005) Long-range interactions between three transcriptional enhancers, active Vkappa gene promoters, and a 3′ boundary sequence spanning 46 kilobases. Molecular and Cellular Biology 25 3220-3231
Liu Z, Yu Y, Jiang Y and Li J (2002) Growth hormone increases lung NF-kB activation and lung microvascular injury induced by lipopolysaccharide in rats. Annals of Clinical Laboratory Science 32 164-170
Liu Z, Zhng HM, Yuan J, Lim T, Sall A, Taylor GA and Yang D (2008) Focal adhesion kinase mediates the IGTP-induced PI3K/Akt survival pathway and further initiates a positive feedback loop of NF-kB activation. Cellular Microbiology in press
Liu ZG (2005) Molecular mechanism of TNF signaling and beyond. Cell Research 15 24-27
Liu Z-g, Hsu H, Goeddel DV and Karin M (1996) Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis, while NF-kB activation prevents cell death. Cell 87 565-575
Liu ZH, Yu YQ, Li WQ and Li JS (2002) Growth hormone increases lung microvascular injury in lipopolysaccharide peritonitis rats: possible involvement of NF-kB activation in circulating neutrophils. Acta Pharmacol Sin 23 887-892
Liu ZJ, Li SW, Liu CA, You HB, Peng Y, Li XH, Chen XF and Gong JP (2005) An experimental study of the inhibitory effects on the activation of endotoxin-induced Kupffer cells through short hairpin RNA targeting interleukin-1 receptor associated kinase-4 gene [Article in Chinese]. Zhonghua Gan Zang Bing Za Zhi 13 819-822
Liu ZJ, Liu XL, Zhao J, Shi YJ, Yan LN, CHen XF, Li XH, You HB, Xu FL and Gong JP (2008) The effects of SOCS-1 on liver endotoxin tolerance development induced by a low dose of lipopolysaccharide are related to dampen NF-kappaB-mediated pathway. Dig Liver Disease in press
Liu ZJ, Yan LN, Li XH, Xu FL, Chen XF, You HB and Gong JP (2008) Up-regulation of IRAK-M is essential for endotoxin tolerance induced by a low dose of lipopolysaccharide in Kupffer cells. Journal of Surgical Research in press
Liu ZJ, Yan LN, Li SW, You HB and Gong JP (2006) Glycine blunts transplantative liver ischemia-reperfusion injury by downregulating interleukin 1 receptor associated kinase-4.
Acta Pharmacologica Sinica 27 1479-1486
Liu ZJ, You HB, Li XH, Chen XF, Liu HZ, Peng Y, Liu CA and Gong JP (2006) The mechanism and treatment phases chosen of glycine for inhibition lipopolysacharide induced Kupffer cells activation [Article in Chinese].Zhonghua Wai Ke Za Zhi 44 189-192
Liu ZM, Chen GG, Ng EK, Leung WK, Sung JJ and Chung SS (2004) Upregulation of heme oxygenase-1 and p21 confers resistance to apoptosis in human gastric cancer cells. Oncogene 23 503-513
Liu ZM, George-Raizen JB, Li S, Meyers KC, Chang MY and Garrard WT (2002) Chromatin structural analyses of the mouse igkappa gene locus reveal new hypersensitive sites specifying a transcriptional silencer and enhancer. Journal of Biological Chemistry 277 32640-32649
Liu Z-P, Galindo RL and Wasserman SA (1997) A role for CKII phosphorylation of the Cactus PEST domain in dorsoventral patterning of the Drosophila embryo. Genes & Development 11 3413-3422
Liu ZQ (2006) Angiotensin II and insulin crosstalk in the cardiovascular system.Zhong Nan Da Xue Xue Bao Yi Xue Ban 31 797-808
Liu-Bryan R and Liote F(2005) Monosodium urate and calcium pyrophosphate dihydrate (CPPD) crystals, inflammation, and cellular signaling. Joint Bone Spine 72 295-302
Liu-Bryan R, Pritzker K, Firestein GS and Terkeltaub R (2005) TLR2 Signaling in chondrocytes drives calcium pyrophosphate dihydrate and monosodium urate crystal-induced nitric oxide generation. Journal of Immunology 174 5016-5023
Liu-Mares W, Sun Z, Bamlet WR, Atkinson EJ, Fridley BL, Slager SL, de Andrade M and Goode EL (2007) Analysis of variation in NF-kB genes and expression levels of NF-kB-regulated molecules. BMC Proceedings 1 S126
Liuwantara D, Elliot M, Smith MW, Yam AO, Walters SN, Marino E, McShea A and Grey ST (2006) Nuclear factor-kB regulates beta-cell death: a critical role for A20 in beta-cell protection. Diabetes 55 2491-2501
Liuzzo G, Santamaria M, Biasucci LM, Narducci M, Colafrancesco V, Porto A, Brugaletta S, Pinnelli M, Rizzello V, Maseri A and Crea F (2007) Persistent activation of nuclear factor kappa-B signaling pathway in patients with unstable angina and elevated levels of C-reactive protein evidence for a direct proinflammatory effect of azide and lipopolysaccharide-free C-reactive protein on human monocytes via nuclear factor kappa-B activation. Journal of theAmerican College of Cardiology 49 185-194
Liversidge J, Dick A, Daniels G, Dawson R (2000) Induction or suppression of a B cell-specific response to self antigen in vivo is dependent upon dendritic cell activation via the TNF-a receptor at the time of antigen uptake. European Journal of Immunology 30 2268-2280
Livolsi A, Busuttil V, Imbert V, Abraham RT and Peyron JF (2001) Tyrosine phosphorylation-dependent activation of NF-kB. Requirement for p56 LCK and ZAP-70 protein tyrosine kinases. European Journal of Biochemistry 268 1508-1515
Li-Weber M, Giaisi M, Baumann S, Palfi K and Krammer PH (2004) NF-kB synergizes with NF-AT and NF-IL6 in activation of the IL-4 gene in T cells. European Journal of Immunogy 34 1111-1118
Li-Weber M, Giaisi M, Baumann S, Treiber MK and Krammer PH (2002) The anti-inflammatory sesquiterpene lactone parthenolide suppresses CD95-mediated activation-induced-cell-death in T-cells. Cell Death & Differentiation 9 1256-1265
Li-Weber M, Giaisi M, Treiber MK and Krammer PH (2002) Vitamin E inhibits IL-4 gene expression in peripheral blood T cells. European Journal of Immunology 32 2401-2408
Li-Weber M, Giasi M and Krammer PH (1998) Involvement of Jun and Rel proteins in up-regulation of interleukin-4 gene activity by the T cell accessory molecule CD28. Journal of Biological Chemistry 273 32460-32466
Li-Weber M, Giaisi M, Treiber MK, Krammer PH (2003) The anti-inflammatory sesquiterpene lactone parthenolide suppresses IL-4 gene expression in peripheral blood T. European Journal of Immunology 32 3587-3597
Li-Weber M and Krammer PH (2003) Function and regulation of the CD95 (APO-1/Fas) ligand in the immune system. Seminars in Immunology 15 145-157
Li-Weber M, Laur O, Dern K and Krammer PH (2000) T cell activation-induced and HIV tat-enhanced CD95(APO-1/Fas) ligand transcription involves NF-kB. European Journal of Immunology 30 661-670
Li-Weber M, Treiber MK, Giaisi M, Palfi K, Stephan N, Parg S and Krammer PH (2005) Ultraviolet irradiation suppresses T cell activation via blocking TCR-mediated ERK and NF-kB signaling pathways. Journal of Immunology 175 2132-2143
Li-Weber M, Weigand MA, Giaisi M, Suss D, Treiber MK, Baumann S, Ritsou E, Breitkreutz R and Krammer PH (2002) Vitamin E inhibits CD95 ligand expression and protects T cells from activation-induced cell death. Journal of Clinical Investigation 110 681-690
Lizarraga F, Maldonado V and Melendez-Zajgla J (2004) Tissue inhibitor of metalloproteinases-2 growth-stimulatory activity is mediated by nuclear factor-kB in A549 lung epithelial cells. International Journal of Biochemistry and Cell Biology 36 1655-1663
Lizundia R, Sauter KS, Taylor G and Werling D (2008) Host species-specific usage of the TLR4-LPS receptor complex. Innate Immunity 14 223-231
Lizzul PF, Aphale A, Malaviya R, Sun Y, Masud S, Dombrovskiy V and Gottlieb AB (2005) Differential expression of phosphorylated NF-kB/RelA in normal and psoriatic epidermis and downregulation of NF-kB in response to treatment with etanercept. Journal of Investigative Dermatology 124 1275-1283
Lleo A, Galea E and Sastre M (2007) Molecular targets of non-steroidal anti-inflammatory drugs in neurodegenerative diseases. Cellular and Molecular Life Sciences 64 1403-1418
Lliu S JM, Buricchi F, Chiarugi P, Morales A, and Fernandez-Checa JC (2007) Dual role of mitochondrial reactive oxygen species in hypoxia signaling: activation of nuclear factor-kB via c-SRC and oxidant-dependent cell death.
Cancer Research 67 7368-7377
Lloyd FP Jr, Slivova V, Valachovicova T and Sliva D (2003) Aspirin inhibits highly invasive prostate cancer cells. International Journal of Oncology 23 1277-1283
Lo AH, Liang YC, Lin-Shiau SY, Ho CT and Lin JK (2002) Carnosol, an antioxidant in rosemary, suppresses inducible nitric oxide synthase through down-regulating nuclear factor-kB in mouse macrophages. Carcinogenesis 23 983-991
Lo AH, Liang YC, Lin-Shiau SY, Ho CT and Lin JK (2002) Carnosol, an antioxidant in rosemary, suppresses inducible nitric oxide synthase through down-regulating nuclear factor-kB in mouse macrophages. Carcinogenesis 23 983-991
Lo AK, Huang DP, Lo KW, Chui YL, Li HM, Pang JC and Tsao SW (2004) Phenotypic alterations induced by the Hong Kong-prevalent Epstein-Barr virus-encoded LMP1 variant (2117-LMP1) in nasopharyngeal epithelial cells. International Journal of Cancer 109 919-925
Lo AK, To KF, Lo KW, Lung RW, Hui JW, Liao G and Haywards SD (2007) Modulation of LMP1 protein expression by EBV-encoded microRNAs. Proceedings of the National Academy of Sciences USA in press
Lo CJ (2003) Mapk regulation of prostaglandin E2 production by lipopolysaccharide-stimulated macrophages is not dependent on nuclear factor kB(2). Journal of Surgical Research 113 189-194
Lo D, Feng L, Li L, Carson MJ, Crowley M, Pauza M, Nguyen A and Reilly CR (1999) Integrating innate and adaptive immunity in the whole animal. Immunology Reviews 169 225-239
Lo JC, Basak S, James ES, Quiambo R, Kinsella MC, Alegre ML, Weih F, Franzoso G, Hoffmann A and Fun YX (2005) Coordination between NF-kB family members p50 and p52 is essential for mediating LTbetaR signals in the development and organization of secondary lymphoid tissues. Blood 107 1048-1055
Lo JC, Chin RK, Lee Y, Kang HS, Wang Y, Weinstock JV, Banks T, Ware CF, Franzoso G and Fu YX (2003) Differential regulation of CCL21 in lymphoid/nonlymphoid tissues for effectively attracting T cells to peripheral tissues. Journal of Clinical Investigation 112 1495-1505
Lo YC, Maddrieni Y, Chung JY, Rich RL, Myszka DG and Wu H (2008) High-affinity interaction between IKKb and NEMO. Biochemistry 47 3109-3116
Lobanova YS, Scherbakov AM, Shatskaya VA and Krasil’nikov MA (2007) Mechanism of estrogen-induced apoptosis in breast cancer cells: role of the NF-kB signaling pathway. Biochemistry (Mosc) 72 320-327
Lobigs M, Mullbacher A and Regner M (2003) MHC class I up-regulation by flaviviruses: Immune interaction with unknown advantage to host or pathogen. Immunol Cell Biol 81 217-223
Lobner K and Fuchtenbusch M (2004) Inflammation and diabetes [Article in German]. MMW Fortschr Med 146 32-36
Lobry C, Lopez T, Israel A and Weil R (2007) Negative feedback loop in T cell activation through IkB kinase-induced phosphorylation and degradation of Bcl10.Proceedgins of the National Academy of Sciences USA 104 908-913
Lobry C and Weil R (2007) Regulation of NF-kB pathway in T lymphocytes [Article in French]. Medicine Sciences (Paris) 23 857-861
Locatelli C, Rosso R, Santos-Silva MC, de Souza CA, Licinio MA, Leal P, Bazzo ML, Yunes RA and Creczynski-Pasa TB (2008) Ester derivatives of gallic acid with potential toxicity toward L1210 leukemia cells. Bioorganic Medicinal Cehmistry in press
Locher CP, Witt SA and Levy JA (2001) The nuclear factor kB and Spl binding sites do not appear to be involved in virus suppression by CD8 T lymphocytes. AIDS 15 2455-2457
Locigno R, Antoine N, Bours V, Daukandt M, Heinen E and Castronovo V (2000) TNP-470, a potent angiogenesis inhibitor, amplifies human T lymphocyte activation through an induction of nuclear factor-kB, nuclear factor-AT, and activation protein-1 transcription factors. Laboratory Investigation 80 13-21
Locker J, Tian J, Carver R, Concas D, Cossu C, Ledda-Columbano GM and Columbano A (2003) A common set of immediate-early response genes in liver regeneration and hyperplasia. Hepatology 38 314-325
Lockett AD, Goebl MG and Harrington MA (2008) Transient membrane recruitment of IRAK-1 in response to LPS and IL-1beta requires TNF R1. American Journal of Physiology: Cellular Physiology in press
Locksley RM, Killeen N and Lenardo MJ (2001) The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 104 487-501
Lockyer JM, Colladay JS, Alperin-Lea WL, Hammond T and Buda AJ (1998) Inhibition of nuclear factor-kB-mediated adhesion molecule expression in human endothelial cells. Circulation Research 82 314-320
Loercher A, Lee TL, Ricker JL, Howard A, Geoghegen J, Chen Z, Sunwoo JB, Sitcheran R, Chuang EY, Mitchell JB, Baldwin AS Jr and Van Waes C (2004) Nuclear Factor-kB is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma. Cancer Research 64 6511-6523
Loeser RF, Yammani RR, Carlson CS, Chen H, Cole A, Im HJ, Bursch LS and Yan SD (2005) Articular chondrocytes express the receptor for advanced glycation end products: Potential role in osteoarthritis. Arthritis & Rheumatism 52 2376-2385
Loeuillet C, Martinon F, Perez C, Munoz M, Thome M and Meylan PR (2006) Mycobacterium tuberculosis subverts innate immunity to evade specific effectors.Journal of Immunology 177 6245-6255
Loewe R, Pillinger M, de Martin R, Mrowietz U, Groger M, Holnthoner W, Wolff K, Wiegrebe W, Jirovsky D and Petzelbauer P (2020) Dimethylfumarate inhibits tumor-necrosis-factor-induced CD62E expression in an NF-kB-dependent manner. Journal of Investigative Dermatology 117 1363-1368
Lofquist AK, Mondal K, Morris JS and Haskill JS (1995) Transcription-independent turnover of IkBa during monocyte adherence: implications for a translational component regulating IkBa/MAD-3 mRNA levels. Molecular and Cellular Biology 15 1737-1746
Logan RM, Gibson RJ, Bowen JM, Stringer AM, Sonis ST and Keefe DM (2007) Characterisation of mucosal changes in the alimentary tract following administration of irinotecan: implications for the pathobiology of mucositis.Cancer Chemotherapy and Pharmacology in press
Logan RM, Gibson RJ, Sonis ST and Keefe DM (2007) Nuclear factor-kB (NF-kB) and cyclooxygenase-2 (COX-2) expression in the oral mucosa following cancer chemotherapy. Oral Oncology 43 395-401
Logan RM, Stringer AM, Bowen JM, Gibson RJ, Sonis ST and Keefe DM (2008) Is the pathobiology of chemotherapy-induced alimentary tract mucositis influenced by the type of mucotoxic drug administered? Cancer Chemotherapy and Pharmacology in press
Logan RM, Stringer AM, Bowen JM, Gibson RJ, Sonis ST and Keefe DM (2008) Serum levels of NF-kB and pro-inflammatory cytokines following administration of mucotoxic drugs. Cancer Biology Therapeutics 7 in press
Logani MK, Natarajan M, Makar VR, Bhanushali A and Ziskin MC (2006) Effect of millimeter waves on cyclophosphamide induced NF-kB. Electromagnetic Biology and Medicine 25 23-27
Logeat F, Israël N, Ten R, Blank V, Le Bail O, Kourilsky P and Israël A (1991) Inhibition of transcription factors belonging to the rel/NF-kB family by a transdominant negative mutant. EMBO Journal 10 1827-1832
Logunov DY, Scheblyakov DV, Zubkova OV, Shmarov MM, Rakovskaya IV, Gurova KV, Taraova ND and Burdlya LG (2008) Mycoplasma infection suppresses p53, activates NF-kB and cooperates with oncogenic Ras in rodent fibroblast transformation. Oncogene in press
Lohmann KL, Vandenplas ML, Barton MH, Bryant CE and Moore JN (2007) The equine TLR4/MD-2 complex mediates recognition of lipopolysaccharide from Rhodobacter sphaeroides as an agonist.
Journal of Endotoxin Research 13 235-242
Loiarro M, Capolunghi F, Fanto N, Gallo G, Campo S, Arseni B, Carsetti R, Carminati P, De Santis R, Ruggiero V and Sette C (2007) Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound. Journal of Leukocyte Biology in press
Loiarro M, Sette C, Gallo G, Ciacci A, Fanto N, Mastroianni D, Carminati P and Ruggiero V (2005) Peptide-mediated interference of tir domain dimerization in MyD88 inhibits IL-1-dependent activation of NF-kB. Journal of Biological Chemistry 280 15809-15814
Lomada D, Liu B, Coghlan L, Hu Y and Richie ER (2007) Thymus medulla formation and central tolerance are restored in IKKalpha-/- mice that express an IKKalpha transgene in keratin 5+ thymic epithelial cells. Journal of Immunology 178 829-837
Lomaga MA, Yeh WC, Sarosi I, Duncan GS, Furlonger C, Ho A, Morony S, Capparelli C, Van G, Kaufman S, van der Heiden A, Itie A, Wakeham A, Khoo W, Sasaki T, Cao Z, Penninger JM, Paige CJ, Lacey DL, Dunstan CR, Boyle WJ, Goeddel DV and Mak TW (1999) TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling. Genes & Development 13 1015-1024
Lombardi A, Cantini G, Piscitelli E, Gelmini S, Francalanci M, Mello T, Ceni E, Varano G, Forti G, Rotondi M, Galli A, Serio M and LUconi M (2008) A new mechanism involving Erk contributes to rosiglitazone inhibition of tumor necrosis factor-a and interferon-a inflammatory effects in human endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology in press
Lombardi L et al. 1995. Oncogenic effect of human NFKB-2 in mouse fibroblasts. unpublished data. Cited in Chang C-C, Zhang J, Lombardi L, Neri A and Dalla-Favera R (1995) Rearranged NFKB-2 genes in lymphoid neoplasms code for constitutively active nuclear transactivators. Molecular and Cellular Biology 15 5180-5187
Lombardi L, Ciana P, Cappellini C, Trecca D, Guerrini L, Migliazza A, Maiolo AT and Neri A (1995) Structural and functional characterization of the promoter regions of the NFKB2 gene. Nucleic Acids Research 23 2328-2336
Lombardo E, Alvarez-Barrientos A, Maroto B, Bosca L and Knaus UG (2007) TLR4-mediated survival of macrophages is MyD88 dependent and requires TNF-a autocrine signalling. Journal of Immunology 178 3731-3739
Loncar MB, Al-Azzeh ED, Sommer PS, Marinovic M, Schmehl K, Kruschewski M, Blin N, Stohwasser R, Gott P and Kayademir T (2003) Tumour necrosis factor alpha and nuclear factor kB inhibit transcription of human TFF3 encoding a gastrointestinal healing peptide. Gut 52 1297-1303
Londhe V, McNamara N, Lemjabbar H and Basbaum C (2003) Viral dsRNA activates mucin transcription in airway epithelial cells. FEBS Letters 553 33-38
Londhe VA, Nguyen HT, Jeng JM< Li X, Li C, Tiozzo C, Zhu N and Minoo P (2008) NF-kB induces lung maturation during mouse lung morphogenesis. Developmental Dynamics in press
Long F, Liu H, Hahn C, Sumazin P, Zhang MQ and Zilberstein A (2004) Genome-wide prediction and analysis of function-specific transcription factor binding sites. In Silico Biology 4 0033
Long J, Song N, Liu XP, Guo KJ and Guo RX (2005) Nuclear factor-kB activation on the reactive oxygen species in acute necrotizing pancreatitic rats. World Journal of Gastroenterology 11 4277-4280
Long SM, Laubach VE, Tribble CG, Kaza AK, Fiser SM, Cassada DC, Kern JA and Kron IL (2003) Pyrrolidine dithiocarbamate reduces lung reperfusion injury. Journal of Surgery Research 112 12-18
Longo CR, Arvelo MB, Patel VI, Daniel S, Mahiou J, Grey ST and Ferran C (2003) A20 protects from CD40-CD40 ligand-mediated endothelial cell activation and apoptosis. Circulation 108 1113-1118
Longo CR, Patel VI, Shrikhande GV, Scali ST, Csizmadia E, Daniel S, Sun DW, Grey ST, Arvelo MB and Ferran C (2005) A20 protects mice from lethal radical hepatectomy by promoting hepatocyte proliferation via a p21(waf1)-dependent mechanism. Hepatology 42 156-164
Longo PG, Laurenti L, Gobessi S, Petlickovski A, Pelosi M, Chiusolo P, Sica S, Leone G and Efremov DG (2007) The Akt signaling pathway determines the different proliferative capacity of chronic lymphocytic leukemia B-cells from patients with progressive and stable disease. Leukemia 21 110-120
Longpre F, Garneau P, Christen Y and Ramassamy C (2006) Protection by EGb 761 against beta-amyloid-induced neurotoxicity: involvement of NF-kB, SIRT1, and MAPKs pathways and inhibition of amyloid fibril formation. Free Radical Biology and Medicine 41 1781-1794
Loennechen T, Mathisen B, Hansen J, Lindstad RI, El-Gewely SA, Andersen K, Maelandsmo GM and Winberg JO (2003) Colchicine induces membrane-associated activation of matrix metalloproteinase-2 in osteosarcoma cells in an S100A4-independent manner. Biochemical Pharmacology 66 2341-2353
Loop T, Bross T, Humar M, Hoetzel A, Schmidt R, Pahl HL, Geiger KK and Pannen BH (2004) Dobutamine inhibits phorbol-myristate-acetate-induced activation of nuclear factor-kB in human T lymphocytes in vitro. Anesthesia and Analgesia 99 1508-1515
Loop T, Humar M, Pischke S, Hoetzel A, Schmidt R, Pahl HL, Geiger KK and Pannen BH (2003) Thiopental inhibits tumor necrosis factor alpha-induced activation of nuclear factor kB through suppression of kB kinase activity. Anesthesiology 99 360-367
Loop T, Liu Z, Humar M, Hoetzel A, Benzing A, Pahl HL, Geiger KKJ and Pannen BH (2002) Thiopental inhibits the activation of nuclear factor kB. Anesthesiology 96 1202-1213
Loop T, Scheiermann P, Doviakue D, Musshoff F, Humar M, Roesslein M, Hoetzel A, Schmidt R, Madea B, Geiger KK, Pahl HL and Pannen BH (2004) Sevoflurane inhibits phorbol-myristate-acetate-induced activator protein-1 activation in human T lymphocytes in vitro: potential role of the p38-stress kinase pathway. Anesthesiology 101 710-721
Lopes ES and Araujo HM (2004) The maternal JAK/STAT pathway of Drosophila regulates embryonic dorsal-ventral patterning. Brazilian Journal of Medicine and Biological Research 37 1811-1818
Lopez-Bojorquez LN (2004) Regulation of NF-kB transcription factor. A molecular mediator in inflammatory process [Article in Spanish]. Rev Invest Clin 56 83-92
Lopez-Bojorquez LN, Arechavaleta-Velasco F, Vadillo-Ortega F, Montes-Sanchez D, Ventura-Gallegos JL and Zentella-Dehesa A (2004) NF-kB translocation and endothelial cell activation is potentiated by macrophage-released signals co-secreted with TNF-alpha and IL-1beta. Inflammation Research 53 567-575
Lopez-Franco O, Hernandez-Vargas P, Ortiz-Munoz G, Sanjuan G, Suzuki Y, Ortega L, Blanco J, Egido J and Gomez-Guerrero C (2006) Parthenolide modulates the NF-kB-mediated inflammatory responses in experimental atherosclerosis.Arteriosclerosis, Thrombosis, and Vascular Biology 26 1864-1870
Lopez-Franco O, Suzuki Y, Sanjuan G, Blanco J, Hernandez-Vargas P, Yo Y, Kopp J, Egido J and Gomez-Guerrero C (2002) Nuclear factor-kB inhibitors as potential novel anti-inflammatory agents for the treatment of immune glomerulonephritis. American Journal of Pathology 161 1497-1505
Lopez-Granados E, Keenan JE, Kinney MC, Leo H, Jain N, Ma CA, Winones R, Gelfand EW and Jain A (2008) A novel mutation in NFKBIA/IKBA results in a degradation-resistant N-truncated protein and is associated with ectodermal dysplasia with immunodeficiency. Human Mutation in press
Lopez-Granados E, Temmerman ST, Wu L, Reynolds JC, Follmann D, Liu S, Nelson DL, Rauch F and Jain A (2007) Osteopenia in X-linked hyper-IgM syndrome reveals a regulatory role for CD40 ligand in osteoclastogenesis. Proceedings of theNational Academy of Sciences USA 104 5056-5061
Lopez-Pedrera C, Buendia P. Jose Cuadrado M, Siendones E, Angeles Aguire M, Barbarroja N, Montiel-Duarte C, Torres A, Khamashta M and Velasco F (2005) Antiphospholipid antibodies from patients with the antiphospholipid syndrome induce monocyte tissue factor expression through the simultaneous activation of NF-kB/Rel proteins via the p38 mitogen-activated protein kinase pathway, and of the MEK-1/ERK pathway. Arthritis and Rheumatism 54 301-311
Lopez-Rodriguez C, Aramburu J, Jin L, Rakeman AS, Michino M and Rao A (2001) Bridging the NFAT and NF-kB families: NFAT5 dimerization regulates cytokine gene transcription in response to osmotic stress. Immunity 15 47-58
Lopez-Rodriguez C, Aramburu J, Rakeman AS and Rao A (1999) NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun. Proceedings of the National Academy of Sciences USA 96 7214-7219
Lopez-Rovira T, Chalaux E, Rosa JL, Bartrons R, Ventura F (2000) Interaction and functional cooperation of NF-kB with Smads: transcriptional regulation of the JunB promoter. Journal of Biological Chemsitry 275 28937-28946
Lopez-Urrutia L, Alonso A, Bayon Y, Nieto ML, Orduna A and Sanchez Crespo M (2001) Brucella lipopolysaccharides induce cyclooxygenase-2 expression in monocytic cells. Biochemical and Biophysical Research Communications 289 372-375
Lora JM, Zhang DM, Liao SM, Burwell T, King AM, Barker PA, Singh L, Keaveney M, Morgenstern J, Gutierrez-Ramos JD, Coyle AJ and Frazer CC (2005) TNF-a triggers mucus production in airway epithelium through an IKKb dependent mechanism. Journal of Biological Chemistry 280 36510-36517
Lorente G, Nelson A, Mueller S, Kuo J, Urfer R, Nikolich K and Foehr ED (2005) Functional comparison of long and short splice forms of RPTPbeta: Implications for glioblastoma treatment. Neuro-oncology 7 154-163
Lorentz A, Klopp I, Gebhardt T, Manns MP and Bischoff SC (2003) Role of activator protein 1, nuclear factor-kB, and nuclear factor of activated T cells in IgE receptor-mediated cytokine expression in mature human mast cells. Jorunal of Allergy and Clinical Immunology 111 1062-1068
Lorenzen J, Shah R, Biser A, Staicu SA, Niranjan T, Garcia AM, Gruenwald A, Thomas DB, Shatat IF, Supe K, Woroniecki RP and Susztak K (2008) The role of osteopontin in the development of albuminuria. Journal of the American Society of Nephrology 19 884-890
Lorenzo O, Ruiz-Ortega M, Suzuki Y, Ruperez M, Esteban V, Sugaya T and Egido J (2002) Angiotensin III activates nuclear transcription factor-kB in cultured mesangial cells mainly via AT(2) receptors: studies with AT(1) receptor-knockout mice. Journal of the American Society of Nephrology 13 1162-1171
Loreto SD, Sebastiani P, Benedetti E, Zimmitti V, Caracciolo V, Amicarelli F, Cimini A and Adorno D (2006) Transient maintenance in bioreactor improves health of neuronal cells. In Vitro Cellular & Developmental Biology: Animal 42 134-142
Lories RJ, Derese I, de Bari C and Luyten FP (2007) Evidence for uncoupling of inflammation and joint remodeling in a mouse model of spondylarthritis. Arthritis and Rheumatism 56 489-497
Lorkowski S, Rust S, Engel T, Jung E, Tegelkamp K, Galinski EA, Assmann G and Cullen P (2001) Genomic sequence and structure of the human ABCG1 (ABC8) gene. Biochemical and Biophysical Research Communications 280 121-131
Lorne E, Zmijewski JW, Zhao X, Liu G, Tsuruta Y, Park YJ, Dupont H and Abraham E (2008) Role of extracellular superoxide in neutrophil activation: interactions between xanthine oxidase and TLR-4 induce proinflammatory cytokine production. American Journal of Physiology: Cellular Physiology in press
Lorz C, Benito-Martin A, Boucherot A, Ucero AC, Rastaldi MP, Henger A, Armelloni S, Santamaria B, Berthier CC, Kretzler M, Egido J and Ortiz A (2008) The death ligand TRAIL in diabetic nephropathy. Journal of the American Society of Nephrology in press
Los GV, Encell LP. McDougall MG, Hartzell DD, Karassina N, Zimprich C, Wood MG, Learish R, Ohana RF, Urh M, Simpson D, Mendez J, Zimmerman K, Otto P, Vidugiris G, Zhu J, Darzins A, Klaubert DH, Bulleit RF and Wood KV (2008) HaloTag: a novel protein labeling technology for cell imaging and protein analysis. ACS Chem Biol in press
Los M, Droge W, Stricker K, Baeuerle PA and Schulze-Osthoff K (1995) Hydrogen peroxide as a potent activator of T lymphocyte functions. European Journal of Immunology 25 159-165
Los M, Schenk H, Hexel K, Baeuerle PA, Droge W and Schulze-Osthoff K (1995) IL-2 gene expression and NF-kB activation through CD28 requires reactive oxygen production by 5-lipoxgenase. EMBO Journal 14 731-740
Loscher CE, Draper E, Leavy O, Kelleher D, Mills KH and Roche HM (2005) Conjugated linoleic acid suppresses NF-kB activation and IL-12 production in dendritic cells through ERK-mediated IL-10 induction. Journal of Immunology 175 4990-4998
Loser K, Mehling A, Loeser S, Apelt J, Kuhn A, Grabbe S, Schwarz T, Penninger JM and Beissert S (2006) Epidermal RANKL controls regulatory T-cell numbers via activation of dendritic cells. Nature Medicine 12 1372-1379
Löser P, Jennings GS, Strauss M and Sandig V (1998) Reactivation of the previously silenced cytomegalovirus major immediate-early promoter in the mouse liver: involvement of NFkB. Journal of Virology 72 180-190
Losick VP and Iseberg RR (2006) NF-kB translocation prevents host cell death after low-dose challenge by Legnionella pneumophila. Journal of Experimental Medicine 2-3 2177-2189
Loskog A, Giandomenico V, Rossig C, Pule M, Dotti G and Brenner MK (2006) Addition of the CD28 signaling domain to chimeric T-cell receptors enhances chimeric T-cell resistance to T regulatory cells. Leukemia 20 1819-1828
Lossdorfer S, Fiekens D Salik MI, Gotz W and Jager A (2008) Subculture affects the phenotypic expression of human periodontal ligament cells and their response to fibroblast growth factor-2 and bone morphogenetic protein-7 in vitro. Journal of Periodontao Research in press
Lossner D, Abou-Ajram C, Benge A and Reuning U (2008) Integrin alphavbeta3 mediates upregulation of epidermal growth-factor receptor expression and activity in human ovarian cancer cells. International Journal of Biochemistry and Cell Biology in press
Lossos IS (2007) The endless complexity of lymphocyte differentiation and lymphomagenesis: IRF-4 downregulates BCL6 expression. Cancer Cell 12 189-191
Lotocki G, Alonso OF, Dietrich WD and Keane RW (2004) Tumor necrosis factor receptor 1 and its signaling intermediates are recruited to lipid rafts in the traumatized brain. Journal of Neuroscience 24 11010-11016
Lotocki G, de Rivero Vaccaari JP, Perez ER, ALonso OF, Curbelo K, Keane RW and Dietrich WD (2006) Therapeutic hypothermia modulates TNFR1 signaling in the traumatized brain via early transient activation of the JNK pathway and suppression of XIAP cleavage. European Journal of Neuroscience 24 2283-2290
Lotz M, Gutle D, Walther S, Menard S, Bogdan C and HOrnef MW (2006) Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells. Journal ofExperimental Medicine 203 973-984
Lotz S, Aga E, Wilde I, Van Zandbergen G, Hartung T, Solbach W and Laskay T (2004) Highly purified lipoteichoic acid activates neutrophil granulocytes and delays their spontaneous apoptosis via CD14 and TLR2. Journal of Leukocyte Biology 75 467-477
Lou H, and Kaplowitz N (2007) Glutathione depletion down-regulates tumor necrosis factor (TNF) a-induced NF-kB activity via IkB kinase (IKK)-dependent and -independent mechanisms. Journal of Biological Chemistry 282 29470-29481
Lou HY, Wei XB, Zhang B, Sun X and Zhang XM (2007) Hydroxyethylpuerarin attenuates focal cerebral ischemia-reperfusion injury in rats by decreasing TNF-alpha expression and NF-kB activity. Yao Xue Xue Bao 42 710-715
Lou HY, Zhang XM, Wei XB, Wang RX and Sun X (2004) Anti-inflammatory effect of hydroxyethylpuerarin on focal brain ischemia/reperfusion injury in rats. Chinese Journal of Physiology 47 197-201
Lou SY, Liu Y, Chen WH, Ying J, He YM and Wang WJ (2008) Pollen Typhae total flavones inhibit expression of interleukin-6 in C2C12 skeletal muscle cells cultured with palmitate [Article in Chinese]. Zhong Xi Yi Jie He Xue Bao 6 488-492
Louis H, Lacolley P, Kakou A, Cattan V, Daret D, Safar M, Bonnet J and Daniel Lamaziere JM (2006) Early activation of internal medial smooth muscle cells in the rabbit aorta after mechanical injury: relationship with intimal thickening and pharmacological applications. Clinical and Experimental Pharmacology and Physiology 33 131-138
Loukinova E, Chen Z, Van Waes C and Dong G (2001) Expression of proangiogenic chemokine Gro 1 in low and high metastatic variants of Pam murine squamous cell carcinoma is differentially regulated by IL-1alpha, EGF and TGF-beta1 through NF-kB dependent and independent mechanisms. International Journal of Cancer 94 637-644
Lousse JC, Van Langendonckt A, Gonzalez-Ramos R, Defrere S, Renkin E and Donnez J (2008) Increased activation of nuclear factor-kappa B (NF-kB) in isolated peritoneal macrophages of patients with endometriosis. Fertility and Sterility in press
Lovborg H, Oberg F, Rickardson L, Gullbo J, Nygren P and Larsson R (2006) Inhibition of proteasome activity, nuclear factor-kB translocation and cell survival by the antialcoholism drug disulfiram. International Journal of Cancer118 1577-1580
Love S (2003) Apoptosis and brain ischaemia. Progress in Neuropsychopharmacology, Biology and Psychiatry 27 267-282
Loveridge CJ, Macdonald AD, Thoms HC, Dunlop MG and Stark LA (2008) The proapoptotic effects of sulindac, sulindac sulfone and indomethacin are mediated by nucleolar translocation of the RelA(p65) subunit of NF-kB. Oncogene 27 2648-2655
Loverre A, Ditonno P, Crovace A, Gesualdo L, Ranieri E, Pontrelli P, Stallone G, Infante B, Schena A, Di Paolo S, Capobianco C, Ursi M, Palazzo S, Battaglia M, Selvaggi FP, Schena FP and Grandaliano G (2004) Ischemia-reperfusion induces glomerular and tubular activation of proinflammatory and antiapoptotic pathways: differential modulation by rapamycin. Journal of the American Scoiety of Nephrology 15 2675-2686
Lowe EP, Wei D, Rice PJ, Li C, Kalbfleisch J, Browder IW and Williams DL (2002) Human vascular endothelial cells express pattern recognition receptors for fungal glucans which stimulates nuclear factor kB activation and interleukin 8 production. American Surgery 68 508-517
Lowenthal JW, Ballard DW, Böhnlein E and Greene WC (1989) Tumor necrosis factor a induces proteins that bind specifically to kB-like enhancer elements and regulate interleukin 2 receptor a-gene expression in primary human T lymphocytes. Proceedings of the National Academy of Sciences USA 86 2331-2335
Loza MJ, Foster S, Peters SP and Penn RB (2006) Beta-agonists modulate T cell functions via direct actions on type 1 and type 2 cells. Blood 107 2052-2060
Lozano FS, Lopez-Novoa JM, Rodriguez JM< Barros MB, Garcia-Criado FJ, Nocolas JL, Parreno A, Revilla J, and Gomez-Alonso A (2005) Exogenous nitric oxide modulates the systemic inflammatory response and improves kidney function after risk-situation abdominal aortic surgery. Journal of Vascular Surgery 42 129-139
Lu B, Wang L, Medan D, Toledo D, Huang C, Chen F, Shi X and Rojanasakul Y (2002) Regulation of Fas (CD95)-induced apoptosis by nuclear factor-kB and tumor necrosis factor-a in macrophages. American Journal of Physiology: Cell Physiology 283 C831-C838
Lu C, He JC, Cai W, Liu H, Zhu L and Vlassara H (2004) Advanced glycation endproduct (AGE) receptor 1 is a negative regulator of the inflammatory response to AGE in mesangial cells. Proceedings of the National Academy of Sciences USA 101 11767-11772
Lu CC, Lai HC, Hsieh SC and Chen JK (2008) Resveratrol ameliorates Serratia marcescens-induced acute pneumonia in rats. Journal of Leukocyte Biology 83 1028-1037
Lu D, Thompson JD, Gorski GK, Rice NR, Mayer MG and Yunis JJ (1991) Alterations at the rel locus in human lymphoma. Oncogene 6 1235-1241
Lu DY, Tang CH, Liou HC, Teng CM, Jeng KC, Kuo SC, Lee FY and Fu WM (2007) YC-1 attenuates LPS-induced proinflammatory responses and activation of nuclear factor-kB in microglia.
British Journal of Pharmacology 151 396-405
Lu G, Shimizu I, Cui X, Itonaga M, Tamaki K, Fukuno H, Inoue H, Honda H and Ito S (2003) Antioxidant and antiapoptotic activities of idoxifene and estradiol in hepatic fibrosis in rats. Life Sciences 74 897-907
Lu H, Wu JY, Beswick EJ, Ohno T, Odenbreit S, Haas R, R
eyes VE, Kita M, Graham DY and Yamaoka Y (2007) Functional and intracellular signalling differences associated with the Helicobacter pylori AlpAB adhesin from Western and East Asian strains. Journal of Biological Chemistry 282 6242-6254
Lu H, Wu JY, Kudo T, Ohno T, Graham DY and Yamaoka Y (2005) Regulation of interleukin-6 promoter activation in gastric epithelial cells infected with Helicobacter pylori. Molecular Biology of the Cell 16 4954-4966
Lu H, Wu L and Zeng Y (2006) The effect of nuclear factor-kappaB protein expression in spiral ganglion cells of cochlea by overdosage sodium salicylate injection in guinea pigs [Article in Chinese]. Lin Chuang Er Bi Yan Hou Ke Za Zhi 20 891-893
Lu H, Zhu ZG, Yao XX, Yan C, Ji J, Liu BY, Yin HR and Lin YZ (2005) Study of hepatic injury during stop-flow chemotherapy [Article in Chinese]. Zhonghua Wei Chang Wai Ke Za Zhi 8 74-77
Lu H, Zhu ZG, Yao XX, Zhao R, Yan C, Zhang Y, Liu BY, Yin HR and Lin YZ (2005) Hepatic preconditioning of doxorubicin in stop-flow chemotherapy: NF-kB/IkB-a pathway and expression of HSP72. World Journal of Gastroenterology 11 2136-2141
Lu HK, Yeh KC, Wu MF, Li CL and Tseng CC (2008) An acute injection of Porphyromonas gingivalis lipopolysaccharide modulates the OPG/RANKL system and interleukin-6 in an ovariectomized mouse model. Oral Microbiology and Immunology 23 220-225
Lu HL, Yang CY, Chen HC, Hung CS, Chiang YC and Ting LP (2008) A novel alternatively spliced interleukin-1 receptor accessory protein mIL-1RAcP687.Molecular Immunology 45 1374-1384
Lu HT, Liang YC, Sheu MT, Ho HO, Lin YT, Hsieh MS and Chen CH (2008) Disease-modifying effects of Glucosamine HCl involving regulation of metalloproteinases and chemokines activated by interleukin-1beta in human primary synovial fibroblasts. Journal of Cellular Biochemistry 104 38-50
Lu J and Jin J (2006) Mechanisms of arsenic trioxide induced tumor cell apoptosis in myelodysplastic syndrome mice model in vivo [Article in Chinese].Zhonghua Er Ke Za Zhi 44 782-786
Lu JW, Wang H, Yan-Li J, Zhang C, Ning H, Li XY, Zhang H, Duan ZH, Zhao L, Wei W and Xu DX (2008) Differential effects of pyrrolidine dithiocarbamate on TNF-a-mediated liver injury in two different models of fulminant hepatitis. Journal of Hepatology 48 442-452
Lu K, Liang CL, Chen HJ, Chen SD, Hsu HC, Chen YC, Hsu FF and Cho CL (2003) Nuclear factor-kB-regulated cyclooxygenase-2 expression in surgery-associated paraspinal muscle injury in rats. Journal of Neurosurgery 98 181-187
Lu KT, Sinquett FL, Dryer RL, Song C and Covey LR (2006) c-Rel plays a key role in deficient activation of B cells from a non-X-linked hyper IgM patient. Blood 108 3769-3776
Lu L, Chen SS, Zhang JQ, Ramires FJ and Sun Y (2004) Activation of nuclear factor-kB and its proinflammatory mediator cascade in the infarcted rat heart. Biochemical and Biophysical Research Communications 321 879-885
Lu L, Wei L, Peng G, Mu Y, Wu K, Kang L, Yan X, Shu Y and Wu J (2008) NS3 protein of hepatitis C virus regulates cyclooxygenase-2 expression through multiple signaling pathways. Virology 371 61-70
Lu LF, Gondek DC, Scott ZA and Noelle RJ (2005) NFkB-inducing kinase deficiency results in the development of a subset of regulatory T Cells, which shows a hyperproliferative activity upon glucocorticoid-induced TNF receptor family-related gene stimulation. Journal of Immunology 175 1651-1657
Lu LL, Puri M, Horvath CM and Sen GC (2008) Select paramysociral V proteins inhibit IRF3 activation by acting as alternative substrates for inhibitor of kB kinase epsilon (IIKe)/TBK1. Journal of Biological Chemistry 283 14269-14276
Lu M, Dou QP, Kitson RP, Smith DM and Goldfarb RH (2006) Differential effects of proteasome inhibitors on cell cycle and apoptotic pathways in human YT and Jurkat cells. Journal of Cell Biochemistry 97 122-134
Lu M, Lin SC, Huang Y, Kang YJ, Rich R, Lo YC, Myszka D, Han J and Wu H (2007) XIAP induces NF-kB activation via the BIR1/TAB1 interaction and BIR1 dimerization. Molecular Cell 26 689-702
Lu PH, Chueh SC, Kung FL, Pan SL, Shen YC and Guh JH (2007) Ilimaquinone, a marine sponge metabolite, displays anticancer activity via GADD153-mediated pathway. European Journal of Pharmacology 556 45-54
Lu R, Moore PA and Pitha PM (2002) Stimulation of IRF-7 gene expression by tumor necrosis factor alpha: requirement for NFkB transcription factor and gene accessibility. Journal of Biological Chemistry 277 16592-16598
Lu S, Becker KA, Hagen MJ, Yan H, Roberts AL, Mathews LA, Schneider SS, Siegelmann HT, Macbeth KJ, Tirrell SM, Blanchard JL and Jerry DJ (2008) Transcriptional responses to estrogen and progesterone in mammary gland identify networks regulating p53 activity. Endocrinology in press
Lu S, Chen Z, Yang J, Chen L, Gong S, Zhou H, Guo L and Wang J (2008) Overexpression of the PSMB5 gene contributes to bortezomib resistance in T-lymphoblastic lymphoma/leukemia cells derived from Jurkat line. Experimental Hematology in press
Lu SC (2008) Regulation of glutathione synthesis. Molecular Aspects of Medicine in press
Lu SC, Huang ZZ, Yang H and Tsukamoto H (1999) Effect of thioacetamide on the hepatic expression of gamma-glutamylcysteine synthetase subunits in the rat. Toxicology and Applied Pharmacology 159 161-168
Lu SC, Huang ZZ, Yang JM and Tsukamoto H (1999) Effect of ethanol and high-fat feeding on hepatic gamma-glutamylcysteine synthetase subunit expression in the rat. Hepatology 30 209-214
Lu SY, Chang KW, Liu CJ, Tseng YH, Lu HH, Lee SY and Lin SC (2006) Ripe areca nut extract induces G1 phase arrests and senescence-associated phenotypes in normal human oral keratinocyte. Carcinogenesis 27 1273-1284
Lu T, Burdelya LG, Swiatkowski SM, Boiko AD, Howe PH, Stark GR and Gudkov AV (2004) Secreted transforming growth factor {beta}2 activates NF-kB, blocks apoptosis, and is essential for the survival of some tumor cells. Proceedings of the National Academy of Sciences USA 101 7112-7117
Lu T, Sathe SS, Swiatkowski SM, Hampole CV and Stark GR (2004) Secretion of cytokines and growth factors as a general cause of constitutive NFkB activation in cancer. Oncogene 23 2138-2145
Lu T and Stark GR (2004) Cytokine overexpression and constitutive NFkB in cancer. Cell Cycle 3 1114-1117
Lu X, Farmer P, Rubin J and Nanes MS (2004) Integration of the NfkappaB p65 subunit into the vitamin D receptor transcriptional complex: Identification of p65 domains that inhibit 1,25-dihydroxyvitamin D3-stimulated transcription. Journal of Cellular Biochemsitry 92 833-848
Lu X, Gilmore L, He X, Rubin J and Nanes MS (2006) Transcriptional regulation of the osterix (Osx, Sp7) promoter by tumor necrosis factor identifies disparate effets of mitogen-activated protein kinase and NF-kB pathways. Journal of Biological Chemistry 281 6297-6306
Lu X and Ruishu W (2003) Effect of magnesium supplementation on NO and NOS subtypes in cultured human umbilical vein endothelial cells [Article in Chinese]. Sichuan Da Xue Xue Bao Yi Xue Ban 34 138-141
Lu Y, Liu L and Zhao P (2008) Expression of nuclear factor-kB/P65 and fragile histidine triad in colorectal carcinoma and clinical significance thereof [Article in Chinese]. Zhonghua Yi Xue Za Zhi 88 610-614
Lu Y, Wang WJ, Leng JH, Cheng LF, Feng L and Yao HP (2008) Inhibitory effect of triptolide on interleukin-18 and its receptor in rheumatoid arthritis synovial fibroblasts. Inflammation Research in press
Lu Y, Cai Z, Xiao G, Keller ET, Mizokami A, Yao Z, Roodman GD and Zhang J (2007) Monocyte chemotactic protein-1 mediates prostate cancer-induced bone resorption.Cancer Research 67 3646-3653
Lu Y, Fukuda K, Li Q, Kumagai N and Nishida T (2006) Role of nuclear factor-kappaB in interleukin-1-induced collagen degradation by corneal fibroblasts. Experimental Eye Research 83 560-568
Lu Y, Fukuda K, Nakamura Y, Kimura K, Kumagai N, Nishida T (2005) Inhibitory effect of triptolide on chemokine expression induced by proinflammatory cytokines in human corneal fibroblasts. Investigative Ophthalmologyand Vision Science 46 2346-2352
Lu Y, Jamieson L, Braiser AR, Fields AP (2001) NF-kB transactivation is required for atypical protein kinase Cl-mediated cell survival. Oncogene 20 4777-4792
Lu Y, Jamieson L, Brasier AR and Fields AP (2001) NF-kB/RelA transactivation is required for atypical protein kinase C iota-mediated cell survival. Oncogene 20 4777-4792
Lu Y and Wahl LM (2005) Production of matrix metalloproteinase-9 by activated human monocytes involves a phosphatidylinositol-3 kinase/Akt/IKKa/NF-kB pathway. Journal of Leukocyte Biology 78 259-265
Lu Y, Xiao G, Galson DL, Nishio Y, Mizokami A, Keller ET, Yao Z and Zhang J (2007) PTHrP-induced MCP-1 production by human bone marrow endothelial cells and osteoblasts promotes osteoclast differentiation and prostate cancer cell proliferation and invasion in vitro. International Journal of Cancer 121 724-733
Lu Y, Zhou J, Xu C, Lin H, Xiao J, Wang Z and Yang B (2008) JAK/STAT and PI3K/AKT pathways form a mutual transactivation loop and afford resistance to oxidative stress-induced apoptosis in cardiomyocytes. Cellular Physiology and Biochemistry 21 305-314
Lu YC, Touzjian N, Stenzel M, Dorfman T, Sodroski JG and Haseltine WA (1991) The NFkB independent cis-acting sequences in HIV-1 LTR responsive to T-cell activation. Journal of Acquired Immune Deficiency Syndromes 4 173-177
Lu YS, Yeh PY, Chuang SE, Gao M, Kuo ML and Cheng AL (2006) Glucocorticoids enhance cytotoxicity of cisplatin via suppression of NF-kB activation in the glucocorticoid receptor-rich human cervical carcinoma cell line SiHa. Journal ofEndocrinology 188 311-319
Lu Z, Lee EY, Robertson LW, Glauert HP and Spear BT (2004) Effect of 2,2′,4,4′,5,5′-hexachlorobiphenyl (PCB-153) on hepatocyte proliferation and apoptosis in mice deficient in the p50 subunit of the transcription factor NF-kB. Toxicological Science 81 35-42
Lu Z, Tharappel JC, Lee EY, Robertson LW, Spear BT and Glauert HP (2003) Effect of a single dose of polychlorinated biphenyls on hepatic cell proliferation and the DNA binding activity of NF-kB and AP-1 in rats. Molecular Carcinogenesis 37 171-180
Lu ZY, Yu SP, Wei JF and Wei L (2006) Age-related neural degeneration in nuclear-factor kB p50 knockout mice. Neuroscience 139 965-978
Luan B, Zhang Z, Wu Y, Kang J and Pei G (2005) beta-Arrestin2 functions as a phosphorylation-regulated suppressor of UV-induced NF-kB activation. EMBO Journal 24 4237-4246
Luan ZG, Nala PL, Zhang ZD and Ma XC (2006) Therapeutic effects of low molecular weight heparin and aspirin on acute lung injury in rat [Article in Chinese].Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 18 456-458
Lubberts E, Van Den Bersselaar L, Oppers-Walgreen B, Schwarzenberger P, Coenen-De Roo CJ, Kolls JK, Joosten LA and Van Den Berg WB (2003) IL-17 promotes bone erosion in murine collagen-induced arthritis through loss of the receptor activator of NF-kB ligand/osteoprotegerin balance. Journal of Immunology 170 2655-2662
Luberto C, Hassler DF, Signorelli P, Okamoto Y, Sawai H, Boros E, Hazen-Martin DJ, Obeid LM, Hannun YA and Smith GK (2002) Inhibition of TNF-induced cell death in MCF7 by a novel inhibitor of neutral sphingomyelinase. Journal of Biological Chemistry 277 41128-41139
Luberto C, Yoo DS, Suidan HS, Bartoli GM and Hannun YA (2000) Differential effects of sphingomyelin hydrolysis and resynthesis on the activation of NF-kB in normal and SV40-transformed human fibroblasts. Journal of Biological Chemistry 275 14760-14766
Lubin FD, Johnston LD, Sweatt JD and Anderson AE (2005) Kainate mediates nuclear factor-kB activation in hippocampus via phosphatidylinositol-3 kinase and extracellular signal-regulated protein kinase. Neuroscience 133 969-981
Lubin FD, Ren Y, Xu X and Anderson AE (2007) Nuclear factor-kB regulates seizure threshold and gene transcription following convulsant stimulation. Journal ofNeurochemistry in press
Lubin FD and Sweatt JD (2007) The IkB kinase regulates chromatin structure during reconsolidation of conditioned fear memories. Neuron 55 942-957
Lucas GJ, Daroszewska A and Ralston SH (2006) Contribution of genetic factors to the pathogenesis of Paget’s Disease of bone and related disorders. Journal of Bone and Mineral Research 21 P31-P37
Lucas GJ, Mehta SG, Hocking LJ, Stewart TL, Cundy T, Nicholson GC, Walsh JP, Fraser WD, Watts GD, Ralston SH and Kimonis VE (2005) Evaluation of the role of Valosin-containing protein in the pathogenesis of familial and sporadic Paget’s disease of bone. Bone 38 280-285
Lucas PC, Kufa P, Gu S, Kohrt D, Kim DS, Siu K, Jin X, Swenson J and McAllister-Lucas LM (2007) A dual role for the API2 moiety in API2-MALT1-dependent NF-kB activation: heterotypic oligomerization and TRAF2 recruitment. Oncogene in press
Lucas PC, McAllister-Lucas LM and Nunez G (2004) NF-kB signaling in lymphocytes: a new cast of characters. Journal of Cell Science 117 31-39
Lucassen PJ, Muller MB, Holsboer F, Bauer J, Holtrop A, Wouda J, Hoogendijk WJ, De Kloet ER and Swaab DF (2001) Hippocampal apoptosis in major depression is a minor event and absent from subareas at risk for glucocorticoid overexposure. American Journal of Pathology 158 453-468
Luciano BS, Hsu S, Channavajhala PL, Lin LL and Cuozzo JW (2004) Phosphorylation of threonine 290 in the activation loop of Tpl2/Cot is necessary but not sufficient for kinase activity. Journal of Biological Chemistry 279 52117-52123
Lucito R and Schneider RJ (1992) Hepatitis B virus X protein activates transcription factor NF-kB without a requirement for protein kinase C. Journal of Virology 66 983-991
Ludford CG, Purchase HG and Cox HW (1972) Duck infectious anemia virus associated with Plasmodium lophurae. Experimental Parisitology 31 29-38
Ludwig A, Friedel B, Metzkow S, Meiners S, Stangl V, Baumann G and Stangl K (2005) Effect of statins on the proteasomal activity in mammalian endothelial and vascular smooth muscle cells. Biochemical Pharmacoloy 70 520-526
Ludwig A, Lorenz M, Grimbo N, Steinle F, Meiners S, Bartsch C, Stangl K, Baumann G and Stangl V (2004) The tea flavonoid epigallocatechin-3-gallate reduces cytokine-induced VCAM-1 expression and monocyte adhesion to endothelial cells. Biochemical and Biophysical Research Communications 316 659-665
Ludwig H, Khayat D, Giaccone G and Facon T (2005) Proteasome inhibition and its clinical prospects in the treatment of hematologic and solid malignancies. Cancer 104 1794-1807
Ludwig L, Kessler H, Hoang-Vu C, Dralle H, Adler G, Boehm BO and Schmid RM (2003) Grap-2, a novel RET binding protein, is involved in RET mitogenic signaling. Oncogene 22 5362-5366
Ludwig L, Kessler H, Wagner M, Hoang-Vu C, Dralle H, Adler G, Bohm BO and Schmid RM (2001) Nuclear factor-kB is constitutively active in C-cell carcinoma and required for RET-induced transformation. Cancer Research 61 4526-4535
Luedde T, Assmus U, Wuestefeld T, Zu Vilsendorf A, Roskams T, Schmidt-Supprian M, Rajewsky K, Brenner DA, Manns MP, Pasparakis M and Trautwein C (2005) Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion-injury. Journal of Clinical Invesitgation 115 849-859
Luecke HF and Yamamoto KR (2005) The glucocorticoid receptor blocks P-TEFb recruitment by NFkB to effect promoter-specific transcriptional repression. Genes and Development 19 1116-1127
Luedde T, Beraza N, Kotsikoris V, van Loo G, Nenci A, De Vos R, Roskams T, Trautwein C and Pasparakis M (2007) Deletion of NEMO/IKKg in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma. Cancer Cell 11119-132
Luedde T, Heinrichsdorff J, de Lorenzi R, De Vox R, Roskams T and Pasparakis M (2008) IKK1 and IKK2 cooperate to maintain bile duct integrity in the liver. Proceedings of the National Academy of Sciences USA in press
Luedde T, Beraza N and Trautwein C (2006) Evaluation of the role of nuclear factor-kB signaling in liver injury using genetic animal models. Journal ofGastroenterology and Hepatology 21 S43-S46
Luedde T and Trautwein C (2006) Intracellular survival pathways in the liver.Liver International 26 1163-1174
Luengo-Blanco M, Prando C, Bustamante J, Aragao-Filho WC, Soeiro Pereira PV, Rehder J, Padden C, Casanova JL, Newburger PE and COndino-Neto A (2008) Essential role of nuclear factor-kB for NADPH oxidase activity in normal and anhidrotic ectodermal dysplasia leukocytes. Blood in press
Luft FC (2001) Workshop: mechanisms and cardiovascular damage in hypertension. Hypertension 37 594-598
Luftig M, Prinarakis E, Yasui T, Tsichritzis T, Cahir-McFarland E, Inoue JI, Nakano H, Mak TW, Yeh WC, Li X, Akira S, Suzuki N, Suzuki S, Mosialos G and Kieff E (2003) Epstein-Barr virus latent membrane protein 1 activation of NF-kB through IRAK1 and TRAF6. Prcoeedings of the National Academy of Sciences USA 100 15595-15600
Luftig M, Yasui T, Soni V, Kang MS, Jacobson N, McFarland EC, Seed B, Kieff E (2004) Epstein-Barr virus latent infection membrane protein 1 TRAF-binding site induces NIK/IKKa-dependent noncanonical NF-kB activation. Prcoeedings of the National Academy of Sciences USA 101 141-146
Luger TA (2002) Neuromediators-a crucial component of the skin immune system. Journal of Dermatolgoical Science 30 87-93
Luger TA and Brzoska T (2007) alpha-MSH related peptides: a new class of anti-inflammatory and immunomodulating drugs. Annals of Rhematoid Disease 66 Siii52-Siii55
Luhm J, Langenkamp Y Hensel J, Frohn C, Brand JM, Hennig H, Rink L, Koritke P, Wittkopf N, WIlliams DL and Mueller A (2006) Beta-(1-3)-D-glucan modulates DNA binding of nuclear factors kB, AT and IL-6 leading to an anti-inflammatory shift of the IL-1beta/IL-1 receptor antagonist ratio. BMC Immunology 7 5
Luhrs H, Gerke T, Boxberger F, Backhaus K, Melcher R, Scheppach W and Menzel T (2001) Butyrate inhibits interleukin-1-mediated nuclear factor-kB activation in human epithelial cells. Dig Dis Sci 46 1968-1973
Luhrs H, Gerke T, Muller JG, Melcher R, Schauber J, Boxberge F, Scheppach W and Menzel T (2002) Butyrate inhibits NF-kappaB activation in lamina propria macrophages of patients with ulcerative colitis. Scandinavian Journal of Gastroenterology 37 458-466
Luhrs H, Kudlich T, Neumann M, Schauber J, Melcher R, Gostner A, Scheppach W and Menzel TP (2002) Butyrate-enhanced TNFa-induced apoptosis is associated with inhibition of NF-kB. Anticancer Research 22 1561-1568
Lukashev D, Ohta A, Apasov S, Chen JF and Sitkovsky M (2004) Physiologic attenuation of proinflammatory transcription by the G(s) protein-coupled A2A adenosine receptor in vivo. Journal of Immunology 173 21-24
Lukita-Atmadja W, Ito Y, Baker GL and McCuskey RS (2002) Effect of curcuminoids as anti-inflammatory agents on the hepatic microvascular response to endotoxin. Shock 17 399-403
Lukiw WJ (2004) Gene expression profiling in fetal, aged, and Alzheimer hippocampus: a continuum of stress-related signaling. Neurochemical Research 29 1287-1297
Lukiw WJ and Bazan NG (1998) Strong Nuclear Factor-kB DNA binding paralleles cyclooxygenase-2 gene transcription in aging and in sporadic Alzheimer’s diesase superior temporal lobe neocortex. Journal of Neuroscience Research 53 583-592
Lukiw WJ, Percy ME and Kruck TP (2005) Nanomolar aluminum induces pro-inflammatory and pro-apoptotic gene expression in human brain cells in primary culture. Journal of Inorganic Biochemistry 99 1895-1898
Lukiw WJ, Ottlecz A, Lambrou G, Grueninger M, Finley J, Thompson HW and Bazan NG (2003) Coordinate activation of HIF-1 and NF-kB DNA binding and COX-2 and VEGF expression in retinal cells by hypoxia. Investigative Ophthalmology & Visual Science 44 4163-4170
Lum RT, Kerwar SS, Meyer SM, Nelson MG, Schow SR, Shiffman D, Wick MM and Joly A (1998) A new structural class of proteasome inhibitors that prevent NF-kB activation. Biochemical Pharmacology 55 1391-1397
Lun M, Zhang PL, Pellitteri PK, Law A, Kennedy TL and Brown RE (2005) Nuclear factor-kB pathway as a therapeutic target in head and neck squamous cell carcinoma: pharmaceutical and molecular validation in human cell lines using velcade and siRNA/NF-kB. Annals of Clinical Laboratory Science 35 251-258
Lun M, Zhang PL, Siegelmann-Danieli N, Blasick TM and Brown RE (2005) Intracellular inhibitory effects of Velcade correlate with morphoproteomic expression of phosphorylated-nuclear factor-kB and p53 in breast cancer cell lines. Annals of Clinical Laboratory Science 35 15-24
Luna C, Hoa NT, Lin H, Zhang L, Nguyen HL, Kanzok SM and Zheng L (2006) Expression of immune responsive genes in cell lines from two different Anopheline species. Insect Molecular Biology 15 721-729
Lund AH, Turner G, Trubestskoy A, Verhoeven E, Wientjens E, Hulsman D, Russell R, DePinho RA, Lenz J and van Lohuizen M (2002) Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice. Nature Genetics 32 160-165
Lundberg P, Koskinen C, Baldock PA, Lothgren H, Stenberg S, Lerner UH and Oldenborg PA (2006) Osteoclast formation is strongly reduced both in vivo and in vitro in the absence of CD47/SIRPalpha-interaction. Biochemical and BiophysicalResearch Communications 352 444-448
Lundqvist A, Choudhury A, Nagata T, Andersson T, Quinn G, Fong T, Maitland N, Pettersson S, Paulie S and Pisa P (2002) Recombinant adenovirus vector activates and protects human monocyte-derived dendritic cells from apoptosis. Human Gene Therapy 13 1541-1549
Lungu G, Covaleda L, Mendes O, Martini-Stoica H and Stoica G (2007) FGF-1-induced matrix metalloproteinase-9 expression in breast cancer cells is mediated by increased activities of NF-kB and activating protein-1. Molecular Carcinogenesis in press
Luo D, Luo Y, He Y, Zhang H, Zhang R, Li X, Dobrucki WL, Sinusas AJ, Sessa WC and Min W (2006) Differential functions of tumor necrosis factor receptor 1 and 2 signaling in ischemia-mediated arteriogenesis and angiogenesis. AmericanJournal of Pathology 169 1886-1898
Luo FQ and Fu HQ (2005) Effect of growth hormone on acute lung injury [Article in Chinese]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 17 523-526
Luo G, Hershko DD, Robb BW, Wray CJ and Hasselgren PO (2003) IL-1beta stimulates IL-6 production in cultured skeletal muscle cells through activation of MAP kinase signaling pathway and NF-kB. American Journal of Physiology: Regulatory and Integrative Comparative Physiology 284 R1249-R1254
Luo G and Yu-Lee L (2000) Stat5b inhibits NFkB-mediated signaling. Molecular Endocrinology 14 114-123
Luo G, Sun X, Hungness E and Hasselgren PO (2001) Heat shock protects L6 myotubes from catabolic effects of dexamethasone and prevents downregulation of NF-kB. American Journal of Physiology: Regulatory and Integrative Comparative Physiology 281 R1193-R1200
Luo J, Tsuji T, Yasuda H, Sun Y, Fujigaki Y and Hishida A (2008) The molecular mechanisms of the attenuation of cisplatin-induced acute renal failure by N-acetylcysteine in rats. Nephrology, Dialysis and Transplantation in press
Luo JL, Kamata H and Karin M (2005) IKK/NF-kB signaling: balancing life and death – a new approach to cancer therapy. Journal of Clinical Investigation 115 2625-2632
Luo JL, Kamata H and Karin M (2005) The anti-death machinery in IKK/NF-kB signaling. Journal of Clinical Immunology 25 541-550
Luo JL, Maeda S, Hsu LC, Yagita H and Karin M (2004) Inhibition of NF-kB in cancer cells converts inflammation-induced tumor growth mediated by TNFa to TRAIL-mediated tumor regression. Cancer Cell 6 297-305
Luo JL, Tan W, Ricono JM, Korchynskyi O, Zhang M, Gonias SL, Cheresh DA and Karin M (2007) Nuclear cytokine-activated IKKa controls prostate cancer metastasis by repressing Maspin.
Nature 446 690-694
Luo P, Tan Z, Zhang Z, Li H and Mo Z (2008) Inhibitory effects of salvianolic acid B on the high glucose-induced mesangial proliferation via NF-kB-dependent pathway. Biol Pharm BUll 31 1381-1386
Luo Q, Ma X, Wahl SM, Bieker JJ, Crossley M and Montaner LJ (2004) Activation and repression of IL-12 p40 transcription by erythroid kruppel-like factor (EKLF) in macrophages. Journal of Biological Chemistry 279 18451-18456
Luo R, Xiao S, Jiang Y, Jin H, Wang D, Liu M, Chen H and Fang L (2008) Porcine reproductive and respiratory syndrome virus (PRRSV) suppresses interferon-beta production by interfering with the RIG-I signaling pathway. Molecular Immunology in press
Luo SF, Lin WN, Yang CM, Lee SW, Liao CH, Leu YL and Hsiao LD (2006) Induction of cytosolic phospholipase A(2) by lipopolysaccharide in canine tracheal smooth muscle cells: Involvement of MAPKs and NF-kB pathways. Cell Signaling 18 1201-1211
Luo SF, Wang CC, Chien CS, Hsiao LD and Yang CM (2003) Induction of cyclooxygenase-2 by lipopolysaccharide in canine tracheal smooth muscle cells: involvement of p42/p44 and p38 mitogen-activated protein kinases and nuclear factor-kB pathways. Cellular Signaling 15 497-509
Luo WJ, Takakuwa T, Ham MF, Wada N, Liu A, Fujita S, Sakane-Ishikawa E and Aozasa K (2004) Epstein-Barr virus is integrated between REL and BCL-11A in American Burkitt lymphoma cell line (NAB-2). Laboratory Investigation 84 1193-1199
Luo X, Zuo X, Zhou Y, ZHang B, Shi Y, Liu M, Wang K, McMillan DR and Xiao X (2008) Extracellular heat shock protein 70 inhibits TNF-a-induced proinflammatory mediator production in fibroblast-like synoviocytes. Arthritis Research and Therapy 10 R41
Luo Y, Hao Y, Shi TP, Deng WW and Li N (2008) Berberine inhibits cyclin D1 expression via suppressed binding of AP-1 transcription factors to CCND1 AP-1 motif. Acta Pharmacologica Sinica 29 628-633
Luo Y, Hattori A, Munoz J, Qin ZH and Roth GS (1999) Intrastriatal dopamine injection induces apoptosis through oxidation-involved activation of transcription factors AP-1 and NF-kB in rats. Molecular Pharmacology 56 254-264
Luo Y, Kwon HJ, Montano S, Georgiadis M, Goebl MG and Harrinton MA (2006) Phosphorylation of SIMPL modulates RelA associated NF-kB dependent transcription. American Journal of Physiology: Cell Physiology in press
Luo Y, Xie XM and Liu HX (2004) Related inflammation markers among different types of coronary heart disease [Article in Chinese]. Zhong Nan Da Xue Xue Bao Yi Xue Ban 29 227-229
Luppi P, Tse H, Lain KY, Markovic N, Piganelli JD and Deloia JA (2006) Preeclampsia activates circulating immune cells with engagement of the NF-kB pathway. American Journal of Reproductive Immunology 56 135-144
Luque I and Gélinas C (1997) Rel/NF-kB and IkB factors in oncogenesis. Seminars in Cancer Biology (TD Gilmore, ed) 8 103-111
Luque I and Gelinas C (1998) Distinct domains of IkBa regulate c-Rel in the cytoplasm and in the nucleus. Molecular and Cellular Biology 18 1213-1224
Luque I, Zong W-x, Chen C and Gélinas C (2000) N-terminal determinants of IkBa necessary for the cytoplasmic regulation of c-Rel. Oncogene 19 1239-1244
Lukas-Croisier C, Lasala C, Nicaud J, Bedecarras P, Kumar TR, Dutertre M, Matzuk MM, Picard JY, Josso N and Rey R (2003) Follicle-stimulating hormone increases testicular anti-Mullerian hormone (AMH) production through Sertoli cell proliferation and a non-classical cyclic AMP-mediated activation of the AMH gene. Molecular Endocrinology 17 550-561
Luo Y, Xie XM and Liu HX (2004) Effect of atorvastatin on the nuclear factor-kappaB and soluble inter-cellular adhesion molecules-1 in patients with acute coronary syndrome [Article in Chinese]. Zhong Nan Da Xue Xue Bao Yi Xue Ban 29 84-86
Lupertz R, Chovolou Y, Kampkotter A, Watjen W and Kahl R (2007) Catalase overexpression impairs TNF-a induced NF-kB activation and sensitizes MCF-7 cells against TNF-a. Journal of Cellular Biochemistry in press
Luppi P, Cirarelli V, Tse H, Piganelli J and Trucco M (2008) Human C-peptide antagonises high glucose-induced endothelial dysfunction through the nuclear factor-kB pathway. Diabetogia in press
Luschen S, Scherer G, Ussat S, Ungefroren H and Adam-Klages S (2004) Inhibition of p38 mitogen-activated protein kinase reduces TNF-induced activation of NF-kB, elicits caspase activity, and enhances cytotoxicity. Experimental Cell Research 293 196-206
Lush CW, Cepinskas G and Kvietys PR (2000) LPS tolerance in human endothelial cells: reduced PMN adhesion, E-selectin expression, and NF-kB mobilization. American Journal of Physiology: Heart and Circulatry Physiology 278 H853-H861
Lush CW, Cepinskas G and Kvietys PR (2003) Regulation of intestinal nuclear factor-kB activity and E-selectin expression during sepsis: A role for peroxynitrite. Gastroenterology 124 118-128
Lusic M, Marcello A, Cereseto A and Giacca M (2003) Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter. EMBO Journal 22 6550-6561
Luster MI and Simeonova PP (1998) Asbestos induces inflammatory cytokines in the lung through redox sensitive transcription factors. Toxicology Letters 102-103 271-275
Lutgendorf SK, Degeest K, Sung CY, Arevalo JM, Penedo F, Lucci 3rd J, Goodheart M, Lubaroff D, Farley DM Sood AK and Cole SW (2008) Depression, social support, and beta-adrenergic transcription control in human ovarian cancer. Brain Behavio Immunology in press
Luthra R, Luthra MG, Izzo J, Wu TT, Lopez-ALvarez E, Malhotra U, Choi IS, Zhang I and Ajani JA (2006) Biomarkers of response to preoperative chemoradiation in esophageal cancers. Seminars in Oncology 33 11 2-5
Lutz C, Nimpf J, Jenny M, Boecklinger K, Enzinger C, Utermann G, Baier-Bitterlich G and Baier G (2002) Evidence of functional modulation of the MEKK/JNK/cJun signaling cascade by the low-density lipoprotein-receptor related protein (LRP). Journal of Biological Chemistry 277 43143-45151
Lutzky V, Hannawi S and Thomas R (2007) Cells of the synovium in rheumatoid arthritis. Dendritic cells. Arthritis Research and Therapy 9 219
Lux SE, John KM and Bennett V (1989) Analysis of cDNA for human erythrocyte ankyrin indicates a repeated structure with homology to tissue-differentiation and cell-cycle control proteins. Nature 344 36-42
Luyendyk JP, Piper JD, Tencati M, Reddy KV, Holscher T, Zhang R, Luchoomun J, Chen X, Min W, Kunsch C and Mackman N (2007) A novel class of antioxidants inhibit LPS induction of tissue factor by selective inhibition of the activation of ASK1 and MAP kinases. Arteriosclerosis, Thrombosis, and Vascular Biology in press
Luyendyk JP, Schabbauer GA, Tencati M, Holscher T, Pawlinski R and Mackman N (2008) Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages. Journal of Immunology 180 4218-4226
Lv N, Song MY, Kim EK, Park JW, Kwon KB and Park BH (2008) Guggulsterone, a plant sterol, inhibits NF-kB activation and protects pancreatic beta cells from cytokine toxicity. Molecular and Cellular Endocrinology in press
Lv P, Luo HS, Zhou XP, Chireyath PS, Xiao YJ, Si XM and Liu SQ (2006) Thalidomide prevents rat liver cirrhosis via inhibition of oxidative stress.Pathology Research and Practice in press
Lv P, Luo HS, Zhou XP, Xiao YJ, Paul SC, Si XM and Zhou YH (2007) Reversal effect of thalidomide on established hepatic cirrhosis in rats via inhibition of nuclear factor-kB/inhibitor of nuclear factor-kB pathway. Archives of Medical Research 38 15-27
Lv R, Zhou W, Chu C and Xu J (2005) Mechanism of the effect of hydroxyethyl starch on reducing pulmonary capillary permeability in a rat model of sepsis. Annals of Clinical Laboratory Science 35 174-183
Lv R, Shou W, Duan M, Ge Y and Zhong T (2008) Ultrastructural changes, nuclear factor-kB activation, and tumor necrosis factor-a expression in brain after acute normovolemic hemodilution and controlled hypotension in rats. Croatian Medical Journal 49 22-31
Lv R, Zhou ZQ, Wu HW, Jin Y, Zhou W and Xu JG (2006) Hydroxyethyl starch exhibits antiinflammatory effects in the intestines of endotoxemic rats.Anesthesia and Analgesia 103 149-155
Lv R, Zhou W, Yang JJ, Jin Y and Xu JG (2005) Hydroxyethyl starch inhibits intestinal production of cytokines and activation of transcription factors in endotoxaemic rats. Journal of Internal Medicine Research 33 379-388
Lv R, Zhou W, Zhang LD and Xu JG (2005) Effects of hydroxyethyl starch on hepatic production of cytokines and activation of transcription factors in lipopolysaccharide-administered rats. Acta Anaesthesiol Scand 49 635-642
Lv Q, Zhuang YF, Wang WM, Cheng XM, Xu H, Yoshimasa S, Sayoko T, Masamichi N and Kunio K (2004) Suppression of neutrophil immune function in rabbit models of hemorrhagic shock complicated by intra-abdominal hypertension. Di Yi Jun Yi Da Xue Xue Bao 24 325-328
Lwin T, Hazlehurst LA, Li Z, Dessureault S, Sotomayor E, Moscinski LC, Dalton WS and Tao J (2007) Bone marrow stromal cells prevent apoptosis of lymphoma cells by upregulation of anti-apoptotic proteins associated with activation of NF-kB (RelB/p52) in non-Hodgkin’s lymphoma cells. Leukemia in press
Lyakh LA, Sanford M, Chekol S, Young HA and Roberts AB (2005) TGF-b and vitamin D3 utilize distinct pathways to suppress IL-12 production and modulate rapid differentiation of human monocytes into CD83+ dendritic dells. Journal of Immunology 174 2061-2070
Lyakhovich VV, Vavilin VA, Zenkov NK and Menshchikova EB (2006) Active defense under oxidative stress. The antioxidant responsive element. Biochemistry (Moscow) 71 962-974
Lye E, Mirtsos C, Suzuki N, Suzuki S and Yeh WC (2004) The role of IRAK-4 kinase activity in IRAK-4-mediated signaling. Journal of Biological Chemistry 279 40653-40658
Lyle DB, Shallcross JC, Furfor CN, Hitchins VM, Breger JC and Langone JJ (2008) Screening biomaterials for stimulation of nitric oxide-mediated inflammation. Journal of Biomedical Materials Research A in press
Lyle R, Valleley EMA, Sharpe PT and Hewitt JE (1994) An alternatively spliced transcript, p65D2, of the gene encoding the p65 subunit of the transcription factor NF-kB. Gene 138 265-266
Lymperopoulos A, Karkoulias G, Koch WJ and Flordellis CS (2006) a(2)-Adrenergic receptor subtype-specific activation of NF-kB in PC12 cells. Neuroscience Letters 402 210-215
Lynch OT and Gadina M (2004) Ubiquitination for activation: new directions in the NF-kB roadmap. Molecular Intervention 4 144-146
Lynch RA, Etchin J, Battle TE and Frank DA (2007) A small-molecule enhancer of signal transducer and activator of transcription 1 transcriptional activity accentuates the antiproliferative effects of IFN-g in human cancer cells.
Cancer Research 67 1254-1261
Lyng H, Landsverk KS, Kristiansen E, Deangelis PM, Ree AH, Myklebost O, Hovig E and Stokke T (2005) Response of malignant B lymphocytes to ionizing radiation: Gene expression and genotype. International Journal of Cancer 115 935-942
Lynn EG, Siow YL, Frohlich J, Cheung GT and O K (2001) Lipoprotein-X stimulates monocyte chemoattractant protein-1 expression in mesangial cells via nuclear factor-kB. Kidney International 60 520-532
Lyons JG, Patel V, Roue NC, Fok SY, Soon LL, Halliday GM and Gutkind JS (2008) Snail up-regulates proinflammatory mediators and inhibits differentiation in oral keratinocytes. Cancer Research 68 4525-4530
Lysiak JJ, Bang HJ, Nguyen QA and Turner TT (2005) Activation of the nuclear factor kB pathway following ischemia-reperfusion of the murine testis. Journal of Andrology 26 129-135
Lyss G, Knorre A, Schmidt TJ, Pahl HL and Merfort I (1998) The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-kB by directly targeting p65. Journal of Biological Chemistry 273 33508-33516
Lyu SA, Lee SY, Lee SJ, Son SW, Kim MO, Kim GY, Kim YH, Yoon HJ, Kim H, Park DI and Ko WS (2006) Seungma-galgeun-tang attentuates proinflammatory activities through the inhibition of NF-kB signal pathway in the BV-2 microglial cells. Journal of Ethnopharmacology 107 59-66
