References – P
Pace E, Ferraro M, Siena L Melis M, Montalbano AM, Jonson M, Bonsignore MR, Bonsignore G and GjomarkaJ M (2008) Cigarette smoke increases Toll-like receptor 4 and modifies lipopolysaccharide-mediated responses in airway epithelial cells. Immunology in press
Pace E, Gagliardo R, Melis M, La Grutta S, Ferraro M, Siena L, Bonsignore G, Gjomarkaj M, Bousquet J and Vignola AM (2004) Synergistic effects of fluticasone propionate and salmeterol on in vitro T-cell activation and apoptosis in asthma. Journal of Allergy and Clinical Immunology 114 1216-1223
Pace TS, Mletzko TC, Alagbe O, Musselman DL, Nemeroff CB, Miller AH and Heim CM (2006) Increased stress-induced inflammatory responses in male patients with major depression and increased early life stress. American Journal of Psychiatry 163 1630-1633
Pace TW, Hu F and Miller AH (2007) Cytokine-effects on glucocorticoid receptor function: Relevance to glucocorticoid resistance and the pathophysiology and treatment of major depression. Brain Behavior and Immunity 21 9-19
Pacheco TR, Levy M, Collyer JC, de Parra NP, Parra CA, Garay M, Aprea G, MOreno S, Mancini AJ and Paller AS (2006) Incontinentia pigmenti in male patients. Journall of American Academy of Dermatology 55 251-255
Pacifico F, Barone C, Mellone S, Di Jeso B, Consiglio E, Formisano S, Vito P and Leonardi A (2003) Promoter identification of CIKS, a novel NF-kB activating gene, and regulation of its expression. Gene 307 99-109
Pacifico F and Leonardi A (2006) NF-kB in solid tumors. Biochemical Pharmacology in press
Pacifico F, Mauro C, Barone C, Crescenzi E, Mellone S, Monaco M, Chiappetta G, Terrazzano G, Liguoro D, Vito P, Consiglio E, Formisano S and Leonardi A (2004) Oncogenic and anti-apoptotic activity of NF-kB in human thyroid carcinomas. Journal of Biological Chemistry 279 54610-54619
Pacifico F, Paolillo M, Chiappetta G, Crescenzi E, Arena S, Scaloni A, Monaco M, Vascotto C, Tell G, Formisano S and Leonardi A (2007) RbAp48 is a target of NF-kB activity in thyroid cancer. Journal of Clinical Endocrinology and Metabolism 92 1458-1466
Packer L (1998) a-lipoic acid: a metabolic antioxidant which regulates NF-kB signal transduction and protects against oxidative injury. Drug Metabolism Reviews 30 245-275
Packham G (2008) The role of NF-kB in lymphoid malignancies. British Journal of Haematology in press
Padgett DA and Glaser R (2003) How stress influences the immune response. Trends in Immunology 24 444-448
Padmanabhan B, Kataoka K, Umehara T, Adachi N, Yokoyama S and Horikoshi M (2005) Structural similarity between histone chaperone Cia1p/Asf1p and DNA-binding protein NF-kB. Journal of Biochemistry (Tokyo) 138 821-829
Pae HO, Jeong SO, Kim HS, Kim SH, Song YS, Kim SK, Chai KY and Chung HT (2008) Dimethoxycurcumin, a synthetic curcumin analogue with higher metabolic stability, inhibits NO production, inducible NO synthase expression and NF-kB activation in RAW264.7 macrophages activated with LPS. Molecular Nutrtion Food Research in press
Pae HO, Oh GS, Lee BS, Rim JS, Kim YM and Chung HT (2005) 3-Hydroxyanthranilic acid, one of l-tryptophan metabolites, inhibits monocyte chemoattractant protein-1 secretion and vascular cell adhesion molecule-1 expression via heme oxygenase-1 induction in human umbilical vein endothelial cells. Atherosclerosis 187 274-284
Paez PM, Garcia CI and Pasquini JM (2006) Expression of myelin basic protein in two oligodendrologlial cell lines in modulated by apotransferrin through different transcription factors. Journal of Neuroscience Research 83 606-618
Page K, Li J, Zhou L, Iasvoyskaia S, Corbit KC, Soh JW, Weinstein IB, Brasier AR, Lin A, Hershenson MB (2003) Regulation of airway epithelial cell NF-kB-dependent gene expression by protein kinase Cdelta. Journal of Immunology 170 5681-5689
Page K, Lierl KM, Hughes VS, Zhou P, Ledford JR and Wills-Karp M (2008) TLR2-mediated activation of neutrophils in response to German cockroach frass. Journal of Immunology 180 6317-6324
Page S, Fischer C, Baumgartner B, Haas M, Kreusel U, Loidl G, Hayn M, Ziegler-Heitbrock HW, Neumeier D and Brand K (1999) 4-hydroxynonenal prevents NF-kB activation and tumor necrosis factor expression by inhibiting IkB phosphorylation and subsequent proteolysis. Journal of Biological Chemistry 274 11611-11618
Page SM, Gleich GJ, Roebuck KA and Thomas LL (1999) Stimulation of neutrophil interleukin-8 production by eosinophil granule major basic protein. Am J Respir Cell Mol Biol 21 230-237
Pahan K, Jana M, Dasgupta S and Liu X (2002) Induction of nitric oxide synthase in cytokine-stimulated human astrocytes by interleukin-12 P40 monomer. Journal of Neurochemistry 81 54-56
Pahan K and Schmid M (2000) Activation of nuclear factor-kB in the spinal cord of experimental allergic encephalomyelitis. Neuroscience Letters 287 17-20
Pahan K, Jana M, Liu X, Taylor BS, Wood C and Fischer SM (2002) Gemfibrozil, a lipid-lowering drug, inhibits the induction of nitric oxide synthase in human astrocytes. Journal of Biological Chemistry 277 45984-45991
Pahan K, Liu X, McKinney MJ, Wood C, Sheikh FG and Raymond JR (2000) Expression of a dominant-negative mutant of p21(ras) inhibits induction of nitric oxide synthase and activation of nuclear factor-kB in primary astrocytes. Journal of Neurochemistry 74 2288-2295
Pahan K, Liu X, Wood C and Raymond JR (2000) Expression of a constitutively active form of phosphatidylinositol 3-kinase inhibits the induction of nitric oxide synthase in human astrocytes. FEBS Letters 472 203-207
Pahan K, Raymond JR and Singh I (1999) Inhibition of phosphatidylinositol 3-kinase induces nitric-oxide synthase in lipopolysaccharide- or cytokine-stimulated C6 glial cells. Journal of Biological Chemistry 274 7528-7536
Pahan K, Sheikh FG, Liu X, Hilger S, McKinney M and Petro TM (2000) Induction of nitric oxide synthase and activation of NF-kB by interleukin-12 p40 in microglial cells. Journal of Biological Chemistry 276 7899-7905
Pahl A and Brune K (2002) Stabilization of gene expression profiles in blood after phlebotomy. Clinical Chemistry 48 2251-2253
Pahl HL (1999) Activators and target genes of Rel/NF-kB transcription factors. Oncogene 18 6853-6866
Pahl HL (1999) Signal transduction from the endoplasmic reticulum to the cell nucleus. Physiology Reviews 79 683-701
Pahl HL and Baeuerle PA (1994) Oxygen and the control of gene expression. Bioessays 16 497-502
Pahl HL and Baeuerle PA (1995) A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-kB. EMBO Journal 14 2580-2588
Pahl HL and Baeuerle PA (1995) Expression of influenza virus hemagglutinin activates transcription factor NF-kB. Journal of Virology 69 1480-1484
Pahl HL and Baeuerle PA (1996) ER stress-mediated NF-kB activation requires both Ca2+ and reactive oxygen intermediates as second messengers. FEBS Letters 392 129-136
Pahl HL and Baeuerle PA (1997) The ER-overload response: activation of NF-kB. Trends in Biochemical Sciences 22 63-67
Pahl HL, Krauss B, Schulze-Osthoff K, Decker T, Traenckner EB, Vogt M, Myers C, Warring P, Mülbacher A, Czernilofsky AP and Baeuerle PA (1996) The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kB. Journal of Experimental Medicine 183 1829-1840
Pahl HL, Sester M, Burgert H-G and Baeuerle PA (1996) Activation of transcription factor NF-kB by the adenovirus protein E3/19K requires its ER retention. Journal of Cell Biology 132 511-522
Pahlavani MA and Harris MD (1998) Effect of in vitro generation of oxygen free radicals on T cell function in young and old rats. Free Radical Biological Medicine 25 903-913
Pahlevan AA, Wright DJ, Andrews C, George KM, Small PL and Foxwell BM (1999) The inhibitory action of Mycobacterium ulcerans soluble factor on monocyte/T cell cytokine production and NF-kB function. Journal of Immunology 163 3928-3935
Pahlevan AA, Wright DJ, Bradley L, Smith C and Foxwell BM (2002) Potential of rifamides to inhibit TNF-induced NF-kB activation. Journal of Antimicrobial Chemotherapy 49 531-534
Pai S, O’Sullivan B, Abdul-Jabbar I, Peng J, Connoly G, Khanna R and Thomas R (2007) Nasopharyngeal carcinoma-associated Epstein-Barr virus-encoded oncogene latent membrane protein 1 potentiates regulatory T-cell function. Immunology & Cell Biology in press
Pai S, O’Sullivan BJ, Cooper L, Thomas R and Khanna R (2002) RelB nuclear translocation mediated by C-terminal activator regions of Epstein-Barr Virus-encoded latent membrane protein 1 and its effect on antigen-presenting function in B cells. Journal of Virology 76 1914-1921
Pai S and Thomas R (2008) Immune deficiency or hyperactivity of NF-kB illuminates autoimmunity. Journal of Autoimunity in press
Pai SY and Ho IC (2002) c-Rel delivers a one-two punch in Th1 cell differentiation. Journal of Clinical Investigation 110 741-742
Paik J, Lee JY and Hwang D (2002) Signaling pathways for TNFa-induced COX-2 expression: mediation through MAP kinases and NFkB, and inhibition by certain nonsteroidal anti-inflammatory drugs. Advances in Experimental and Medical Biology 507 503-508
Paik YH, Lee KS, Lee HJ, Yang KM, Lee SJ, Lee DK, Han KH, Chon CY, Lee SI, Moon YM and Brenner DA (2006) Hepatic stellate cells primed with cytokines upregulate inflammation in response to peptidoglycan or lipoteichoic acid. LaboratoryInvestigation 86 676-686
Paik YH, Schwabe RF, Bataller R, Russo MP, Jobin C and Brenner DA (2003) Toll-Like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells. Hepatology 37 1043-1055
Paillard F (1999) Induction of apoptosis with I-kB, the inhibitor of NF-kB. Human Gene Therapy 10 1-3
Paimela T, Ryhanen T, Mannermaa E, Ojala J, Kalesnykas G, Salminen A and Kaarniranta K (2007) The effect of 17beta-estradiol on IL-6 secretion and NF-kB DNA-binding activity in human retinal pigment epithelial cells. Immunology Letters in press
Paine AJ and Andreakos E (2004) Activation of signalling pathways during hepatocyte isolation: relevance to toxicology in vitro. Toxicology In Vitro 18 187-193
Paine E, Scheinman R, Baldwin A and Raab-Traub N (1995) Expression of LMP1 in epithelial cells leads to the activation of a select subset of NF-kB/Rel family proteins. Journal of Virology 69 4572-4576
Paintlia AS, Paintlia MK, Singh I and Singh AK (2006) IL-4-induced peroxisome proliferator-activated receptor gamma activation inhibits NF-kB trans activation in central nervous system (CNS) glial cells and protects oligodendrocyte progenitors under neuroinflammatory disease conditions: implication for CNS-demyelinating diseases. Journal of Immunology 1764385-4398
Pajak B and Orzechowski A (2004) Complex forms of immune insufficiency to some cytokines (TNF-alpha, interferons) in colorectal cancers as exemplified by the COLO 205 cell line. Mechanism of resistance with special reference to signaling proteins and cytokines [Article in Polish]. Postepy Hig Med Dosw 58 428-437
Pajak B and Orzechowski A (2005) FLIP–an enemy which might lose the battle against the specific inhibitors of translation [Article in Polish]. Postepy Hig Med Dosw 59 140-149
Pajak B and Orzechowski A (2006) Overview how adenocarcinoma cancer cells avoid immune- and chemotherapy-induced apoptosis.Advances in Medical Sciences 51 39-45
Pajak B and Orzechowski A (2007) IFN-a competes with TNF-a for STAT-1alpha; molecular basis for immune escape of human colon adenocarcinoma COLO 205 cells. Oncology Reports 18 1039-1045
Pajak B, Orzechowski A and Gajkowska B (2008) Molecular basis of parthenolide-dependent proapoptotic activity in cancer cells. Folia Hisochem Cytobiol 46 129-135
Pajonk F, Himmelsbach J, Riess K, Sommer A and McBride WH (2002) The human immunodeficiency Virus (HIV)-1 protease inhibitor saquinavir inhibits proteasome function and causes apoptosis and radiosensitization in non-HIV-associated human cancer cells. Cancer Research 62 5230-5235
Pajonk F and McBride WH (2001) The proteasome in cancer biology and treatment. Radiation Research 156 447-459
Pajonk F, Pajonk K and McBride WH (1999) Inhibition of NF-kB, clonogenicity, and radiosensitivity of human cancer cells. Journal of the National Cancer Institute 91 1956-1960
Pajonk F, Riedisser A, Henke M, McBride WH and Fiebich B (2006) The effects of tea extracts on proinflammatory signaling. BMC Medicine 4 28
Pajonk F, Riess K, Sommer A and McBride WH (2002) N-acetyl-L-cysteine inhibits 26S proteasome function: implications for effects on NF-kB activation. Free Radic Biol Med 32 536-543
Pajonk F, Scholber J and Fiebich B (2005) Hypericin-an inhibitor of proteasome function. Cancer Chemotherapy and Pharmacology 55 439-446
Pajonk F, Weil A, Sommer A, Suwinski R and Henke M (2004) The erythropoietin-receptor pathway modulates survival of cancer cells. Oncogene 23 8987-8991
Pak J and Faller DV (1996) Moloney murine leukemia virus activates NF-kB. Journal of Virology 70 4167-4172
Pal S, Wu J and Wu LP (2007) Microarray analyses reveal distinct roles for Rel proteins in the Drosophila immune response.Developmental and Comparative Immunology in press
Palacios VG, Chung HY, Choi SJ, Kurihara N, Lee JW, Ehrlich LA, Collins R and Roodman GD (2006) Eosinophil chemotactic factor-L (ECF-L) enhances osteoclast formation by increasing ICAM-1 expression. Annalsof the New York Academy of Sciences1068 240-243
Palacios-Callender M, Quintero M, Hollis VS, Springett RJ and Moncada S (2004) Endogenous NO regulates superoxide production at low oxygen concentrations by modifying the redox state of cytochrome c oxidase. Proceedings of teh National Academy of Sciences USA 101 7630-7635
Paldino P, Cummingst DT, Noyce RS and Mossman KL (2006) The IFN-independent response to virus particle entry provides a first line of antiviral defense that is independent of TLRs and retinoic acid-inducible gene I. Journal of Immunology 177 8008-8016
Palaga T, Buranaruk C, Rengpipat S, Fauq AH, Golde TE, Kaufmann SH and Osborne BA (2007) Notch signaling is activated by TLR stimulation and regulates macrophage functions. European Journal of Immunology in press
Palaga T, Miele L, Golde TE and Osborne BA (2003) TCR-mediated notch signaling regulates proliferation and IFN-g production in peripheral T cells. Journal of Immunology 171 3019-3024
Paland N, Rajalingam K, Machuy N, Szczepek A, Wehrl W and Rudel T (2006) NF-kB and inhibitor of apoptosis proteins are required for apoptosis resistance of epithelial cells persistently infected with Chlamydophila pneumoniae. CellularMicrobiology 8 1643-1655
Palanisamy N, Abou-Elella AA, Chaganti SR, Houldsworth J, Offit K, Louie DC, Terayu-Feldstein J, Cigudosa JC, Rao PH, Sanger WG, Weisenburger DD and Chaganti RSK (2002) Similar patterns of genomic alteration characterize primary medistinal large-B-cell lymphoma and diffuse large-B-cell lymphoma. Genes, Chromosomes & Cancer 33 114-122
Palanki M, Gayo-Fung L, Shevlin G, Erdman P, Sato M, Goldman M, Ransone L and Spooner C (2002) Structure-activity relationship studies of ethyl 2-[(3-methyl-2,5-dioxo(3-pyrrolinyl))amino]-4-(trifluoromethyl)pyrimidine-5-carboxylate: an inhibitor of AP-1 and NF-kB mediated gene expression. Bioorganic & Medicinal Chemistry Letters 12 2573
Palanki MS, Erdman PE, Ren M, Suto M, Bennett BL, Manning A, Ransone L, Spooner C, Desai S, Ow A, Totsuka R, Tsao P and Toriumi W (2003) The design and synthesis of novel orally active inhibitors of AP-1 and NF-kB mediated transcriptional activation. SAR of in vitro and in vivo studies. Bioorganic & Medicinal Chemistry Letters 13 4077-4080
Palao G, Santiago B, Galindo MA, Rullas JN, ALcami J, Raminzez JC and Pablos JL (2006) Fas activation of a proinflammatory program in rheumatoid synoviocytes and its regulation by FLIP and caspase 8 signaling. Arthritis and Rheumatism in press
Palayoor ST, Youmell MY, Calderwood SK, Coleman CN and Price BD (1999) Constitutive activation of IkB kinase a and NFkB in prostate cancer cells is inhibited by ibuprofen. Oncogene 18 7389-7394
Palanki MS (2002) Inhibitors of AP-1 and NF-kB mediated transcriptional activation: therapeutic potential in autoimmune diseases and structural diversity. Current Medicinal Chemistry 9 219-227
Palkowitsch L, Leidner J, Ghsoh S and Marienfeld RB (2008) phosphorylation of serine 68 in the IkB B (IKK)-binding domain of NEMO interferes with the structure of the IKK-complex and the TNF-a-induced NF-kB activity. Journal of Biological Chemistry 283 76-86
Pall ML (2007) Nitric oxide synthase partial uncoupling as a key switching mechanism for the NO/ONOO- cycle. MedicalHypotheses in press
Pall ML (2008) Post-radiation syndrome as a NO/ONOO(-) cycle, chronic fatigue syndrome-like disease. Medical Hypotheses in press
Pall ML and Bedient SA (2007) The NO/ONOO-cycle as the etiological mechanism of tinnitus. International Tinnitus Journal 13 99-104
Palladino MA, Johnson TA, Gupta R, Chapman JL and Ojha P (2007) Members of the toll-like receptor family of innate immunity pattern-recognition receptors are abundant in the male rat reproductive tract. Biology of Reproduction 76 958-964
Pallares J, Martinez-Guitarte JL, Dolcet X, Llobet D, Rue M, Palacios J, Prat J and Matias-Guiu X (2004) Abnormalities in the NF-kB family and related proteins in endometrial carcinoma. Journal of Pathology 204 569-577
Palma JP, Kwon D, Clipstone NA and Kim BS (2003) Infection with Theiler’s murine encephalomyelitis virus directly induces proinflammatory cytokines in primary astrocytes via NF-kB activation: potential role for the initiation of demyelinating disease. Journal of Virology 77 6322-6331
Palmby TR, Abe K, Karnoub AE and Der CJ (2005) Vav transformation requires activation of multiple GTPases and regulation of gene expression. Molecular Cancer Research 2 702-711
Palmer BD, Henare K, Woon ST, Sutherland R, Reddy C, Wang LC, Kieda C and Ching LM (2007) Synthesis and biological activity of azido analogues of 5,6-dimethylxanthenone-4-acetic acid for use in photoaffinity labeling. Journal of Medicinal Chemistry in press
Palmer CD, Mutch BE, Workman S, McDaid JP, Horwood NJ and Foxwell BM (2007) Bmx tyrosine kinase regulates TLR4-induced IL-6 production in human macrophages independently of p38 MAPK and NFkB activity. Blood in press
Palmer DH, Chen MJ, Searle PF, Kerr DJ and Young LS (2005) Inhibition of NF-kB enhances the cytotoxicity of virus-directed enzyme prodrug therapy and oncolytic adenovirus cancer gene therapy. Gene Therapy 12 1187-1197
Palmetshofer A, Robson SC and Nehls V (1999) Lysophosphatidic acid activates nuclear factor kB and induces proinflammatory gene expression in endothelial cells. Thrombosis and Haemostosis 82 1532-1537
Palmieri C, Trimboli F, Puca A, Fiume G, Scala G and Quinto I (2004) Inhibition of HIV-1 replication in primary human monocytes by the IkB-aS32/36A repressor of NF-kB. Retrovirology 1 45
Palmquist P, Persson E, Conaway HH and Lerner UH (2002) IL-6, Leukemia inhibitory factor, and Oncostatin M stimulate bone resorption and regulate the expression of receptor activator of NF-kB ligand, osteoprotegerin, and receptor activator of NF-kB in mouse calvariae. Journal of Immunology 169 3353-3362
Palmqvist P, Lundberg P, Lundgren L, Hanstrom L and Lerner UH (2008) IL-1b and TNF-a regulate IL-6-type cytokines in gingival fibroblasts.
Palomba L, Persichini T, Mazzone V, Colasanti M and Cantoni O (2004) Inhibition of NOS-I-dependent NO production by lipopolysaccharide plus Interferon-gamma is mediated by arachidonic acid. Effects on NF-kB activation and late inducible nitric oxide synthase expression. Journal of Biological Chemistry 279 29895-29901
Palombella VJ, Rando OJ, Goldberg AL and Maniatis T (1994) The ubiquitin-proteasome pathway is required for processing the NF-kB1 precursor protein and the activation of NF-kB. Cell 78 773-785
Palona I, Namba H, Mitsutake N, Starenki D, Podtcheko A, Sedliarou I, Ohtsuru A, Saenko V, Nagayama Y, Umezawa K and Yamashita S (2006) BRAFV600E promotes invasiveness of thyroid cancer cells through NF-kB activation. Endocrinology in press
Palova-Jelinkova L, Rozkova D, Pecharova B, Bartova J, Sediva A, Tlaskovlova-Hogenova H, Spisek R and Tuckova L (2005) Gliadin fragments induce phenotypic and functional maturation of human dendritic cells. Journal of Immunology 175 7038-7045
Palozza P, Serini S, Torsello A, Di Nicuolo F, Maggiano N, Ranelletti FO, Wolf FI and Calviello G (2003) Mechanism of activation of caspase cascade during beta-carotene-induced apoptosis in human tumor cells. Nutr Cancer 47 76-87
Palozza P, Serini S, Torsello A, Di Nicuolo F, Piccioni E, Ubaldi V, Pioli C, Wolf FI and Calviello G (2003) beta-Carotene regulates NF-kB DNA-binding Activity by a redox mechanism in human leukemia and colon adenocarcinoma Cells. Journal of Nutrition 133 381-388
Palsson-McDermott EM and O’Neill LA (2004) Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4. Immunology 13 153-162
Paludan SR (2001) Requirements for the induction of interleukin-6 by herpes simplex virus- infected leukocytes. Journal of Virology 75 8008-8015
Paludan SR, Ellermann-Eriksen S and Mogensen SC (1998) NF-kB activation is responsible for the synergistic effect of herpes simplex virus type 2 infection on interferon-g-induced nitric oxide production in macrophages. Journal of General Virology 79 2785-2793
Paludan SR, Ellermann-Eriksen S, Malmgaard L and Mogensen SC (2000) Herpes simplex virus type 2 infection of macrophages impairs IL-4-mediated inhibition of NO production through TNF-a-induced activation of NF-kB. Archives of Virology 145 575-591
Paludan SR, Ellermann-Eriksen S, Malmgaard L, Mogensen SC (2000) Inhibition of NO production in macrophages by interleukin-13 is counteracted by Herpes simplex virus infection throug tumor necrosis factor-a-induced activation of NF-kB. European Cytokine Network 11 275-282
Paludan SR, Malmgaard L, Ellermann-Eriksen S, Bosca L and Mogensen SC (2001) Interferon (IFN)-gamma and Herpes simplex virus/tumor necrosis factor-a synergistically induce nitric oxide synthase 2 in macrophages through cooperative action of nuclear factor-kB and IFN regulatory factor-1. European Cytokine Network 12 297-308
Palumbo R, Galvez BG, Pusterla T, Marchis F, Cossu G, Marcu KB and Bianchi ME (2007) Cells migrating to sites of tissue damage in response to the danger signal HMGB1 require NF-{kappa}B activation. Journal of Cell Biology 179 33-40
Pan D and Courey AJ (1991) The same dorsal binding site mediates both activation and repression in a context-dependent manner. EMBO Journal 11 1837-1842
Pan D, Huang J-D and Courey AJ (1991) Functional analysis of the Drosophila twist promoter reveals a dorsal-binding ventral activator region. Genes & Development 5 1892-1901
Pan F, Shi Y, Li HQ, Zhao JN, Tang SF and Yao ZK (2003) Activation of nuclear factor kB in newborn rats sepsis [Article in Chinese]. Zhonghua Er Ke Za Zhi 41 582-585
Pan G, Ahn EY, Chen Y, Feng G, Reddy V, Jhala NC and McDonald JM (2007) Reciprocal co-expression of Fas and Fas ligand in human cholangiocarcinoma. International Journal of Oncology 31 843-850
Pan G, Wu X, McKenna MA, Feng X, Nagy TR and McDonald JM (2004) AZT enhances osteoclastogenesis and bone loss. AIDS Research & Human Retroviruses 20 608-620
Pan J, Clayton M and Feitelson MA (2004) Hepatitis B virus X antigen promotes transforming growth factor-beta1 (TGF-beta1) activity by up-regulation of TGF-beta1 and down-regulation of alpha(2)-macroglobulin. Journal of General Virology 85 275-282
Pan J and McEver RP (1995) Regulation of the human P-selectin promoter by Bcl-3 and specific homodimeric members of the NF-kB/Rel family. Journal of Biological Chemistry 270 23077-23083
Pan J, Duan LX, Sun BS and Feitelson MA (2001) Hepatitis B virus X protein protects against anti-Fas-mediated apoptosis in human liver cells by inducing NF-kB. Journal of General Virology 82 171-182
Pan MH, Chang YH, Tsai ML, Lai CS, Ho SY, Badmaev V and Ho CT (2008) Pterostilbene suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 in murine macrophages. Journal of Agriculture and Food Chemistry in press
Pan MH, Lai CS, Wang YJ and Ho CT (2006) Acacetin suppressed LPS-induced up-expression of iNOS and COX-2 in murine macrophages and TPA-induced tumor promotion in mice. Biochemical Pharmacology 72 1293-1303
Pan MH, Lin-Shiau SY, Ho CT, Lin JH and Lin JK (2000) Suppression of lipopolysaccharide-induced nuclear factor-kB activity by theaflavin-3,3′-digallate from black tea and other polyphenols through down-regulation of IkB kinase activity in macrophages. Biochemical Pharmacology 59 357-367
Pan Q, Kleer CG, van Golen KL, Irani J, Bottema KM, Bias C, De Carvalho M, Mesri EA, Robins DM, Dick RD, Brewer GJ and Merajver SD (2002) Copper deficiency induced by tetrathiomolybdate suppresses tumor growth and angiogenesis. Cancer Research 62 4854-4859
Pan Q, Kravchenko V, Katz A, Huang S, Ik M, Mathison JC, Kobayashi K, Flavell RA, Schreiber RD, Goeddel D and Ulevitch RJ (2006) NF-kB-inducing kinase regulates selected gene expression in the Nod2 signaling pathway. Infection and Immunity 742121-2127
Pan Q, Petit-Frere C, Stavnezer J and Hammarstrom L (2000) Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3’alpha enhancer. European Journal of Immunology 30 1019-1029
Pan Q, Zhang R, Bai Y, He N and Lu Z (2007) An electrochemical approach for detection of specific DNA-binding protein by gold nanoparticle-catalyzed silver enhancement. Analytical Biochemistry in press
Pan S, Tao Z, Wu L, Xiao B and Chen S (2005) Nuclear factor kB/p65 and cyclooxygenase-2 expression and clinic significance in human laryngeal squamous cell carcinoma [Article in Chinese]. Lin Chuang Er Bi Yan Hou Ke Za Zhi 19 535-537
Pan S, Tsuruta R, Masuda ES, Imamura R, Bazan F, Arai K, Arai N and Miyatake S (2000) NFATz: a novel rel similarity domain containing protein. Biochemical and Biophysical Research Communications 272 765-776
Pan SL, Guh JH, Huang YW, Chang YL, Chang CY, Huang LJ, Kuo SC and Teng CM (2002)
Inhibition of ras-mediated cell proliferation by benzyloxybenzaldehyde. Journal of Biomedical Science 9 622-630
Pan SL, Guh JH, Peng CY, Chang YL, Cheng FC, Chang JH, Kuo SC, Lee FY, Teng CM (2005) A potential role of YC-1 on the inhibition of cytokine release in peripheral blood mononuclear leukocytes and endotoxemic mouse models. Thrombosis and Haemostosis 93 940-948
Pan SL, Huang YW, Guh JH, Chang YL, Peng CY and Teng CM (2003) Esculetin inhibits Ras-mediated cell proliferation and attenuates vascular restenosis following angioplasty in rats. Biochem Pharmacol 65 1897-1905
Pan Y, Chen C, Shen Y, Zhu CH, Wang G, Wang XC, Chen HQ and Zhu MS (2008) Curcumin alleviates dystrophic muscle pathology in mdx mice. Molecules and Cells 25 in press
Pan ZK (1998) Anaphylatoxins C5a and C3a induce nuclear factor kappaB activation in human peripheral blood monocytes. Biochimica et Biophysica Acta 1443 90-98
Pan ZK, Chen LY, Cochrane CG and Zuraw BL (2000) fMet-Leu-Phe stimulates proinflammatory cytokine gene expression in human peripheral blood monocytes: the role of phosphatidylinositol 3-kinase. Journal of Immunology 164 404-411
Pan ZK, Christiansen SC, Ptasznik A and Zuraw BL (1999) Requirement of phosphatidylinositol 3-kinase activity for bradykinin stimulation of NF-kB activation in cultured human epithelial cells. Journal of Biological Chemistry 274 9918-9922
Panattoni M, Sanvito F, Basso V, Doglioni C, Casorati G, Montini E, Bender JR, Mondino A and Pardi R (2008) Targeted inactivation of the COP9 signalosome impairs multiple stages of T cell development. Journal of Experimental Medicine 205 465-477
Pancer Z, Rast JP and Davidson EH (1999) Origins of immunity: transcription factors and homologues of effector genes of the vertebrate immune system expressed in sea urchin coelomocytes. Immunogenetics 49 773-786
Pande V and Ramos MJ (2003) Nuclear Factor kB: a potential target for anti-HIV chemotherapy. Current Medicinal Chemistry 10 1603-1615
Pande V and Ramos MJ (2005) NF-kB in human disease: current inhibitors and prospects for de novo structure based design of inhibitors. Current Medicinal Chemistry 12 357-374
Pande V and Ramos MJ (2005) Molecular recognition of 15-deoxy-Delta(12,14)-prostaglandin J(2) by nuclear factor-kB and other cellular proteins. Bioorganic Medicinal Chemistry Letters in press
Pande V, Sharma RK, Inoue J, Otsuka M and Ramos MJ (2003) A molecular modeling study of inhibitors of nuclear factor kB (p50)–DNA binding. Journal of Computer Aided Molecular Design 17 825-836
Pandey M, Bajaj GD and Rath PC (2004) Induction of the interferon-inducible RNA-degrading enzyme, RNase L, by stress-inducing agents in the human cervical carcinoma cells. RNA Biology 1 21-27
Pandey M, Loskutoff DJ and Samad F (2005) Molecular mechanisms of tumor necrosis factor-alpha-mediated plasminogen activator inhibitor-1 expression in adipocytes. FASEB Journal 19 1317-1319
Pandey MK, Sandur SK, Sung B, Sethi G, Kunnumakkara AB and Agggarwal BB (2007) Butein, a tetrahydroxychalcone, inhibits nuclear factor (NF)-kB and NF-kB-regulated gene expression through direct inhibition of IkB kinase beta on cysteine-179 residue. Journal of Biological Chemistry 282 17340-17350
Pandey MK, Sung B, Ahn KS, Kunnumakkara AB, Chaturvedi MM and Aggarwal BB (2007) Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-kB signaling pathway. Blood110 3517-3525
Pandey MK, Sung B, Kunnumakkara AB, Sethi G, Chaturvedi MM and Aggaral BB (2008) Berberine modifies cysteine 179 of IkB kinase, suppresses nuclear factor-kB-regulated antiapoptotic gene products, and potentiates apoptosis. Cancer Research 68 5370-5379
Pandey R, Destephan CM, Madge LA, May MJ and Orange JS (2007) NKp30 ligation induces rapid activation of the canonical NF-kB pathway in NK cells. Journal of Immunology 179 7385-7396
Pandey R, Maurya R, Singh G, Sathiamoorthy B and Naik S (2005) Immunosuppressive properties of flavonoids isolated from Boerhaavia diffusa Linn. International Immunopharmacology 5 541-553
Pandey S and Agrawal DK (2006) Immunobiology of Toll-like receptors: emerging trends. Immunology & Cell Biology 84 333-341
Pandey SK, He HJ, Chesley A, Juhaszova M, Crow MT and Bernier M (2002) Wortmannin-sensitive pathway is required for insulin-stimulated phosphorylation of inhibitor kB. Endocrinology 143 375-385
Pani B, Cornatzer E, Cornatzer W, Min Shin D, Pittelkow MR, Hovnanian A, Ambudkar IS and Singh BB (2006) Up-regulation of TRPC1 following SERCA2 gene silencing promotes cell survival: a potential role for TRPC1 in Darier’s disease. MolecularBiology of the Cell 17 4446-4458
Pando MP and Verma IM (2000) Signal-dependent and -independent degradation of free and NF-kB-bound IkBa. Journal of Biological Chemistry 275 21278-21286
Pandol SJ, Periskic S, Gukovsky I, Zaninovic V, Jung Y, Zong Y, Solomon TE, Gukovskaya AS and Tsukamoto H (1999) Ethanol diet increases the sensitivity of rats to pancreatitis induced by cholecystokinin octapeptide. Gastroenterology 117 706-716
Panet H, Barzilai A, Daily D, Melamed E and Offen D (2001) Activation of nuclear transcription factor kB (NF-kB) is essential for dopamine-induced apoptosis in PC12 cells. Journal of Neurochemistry 77 391-398
Pang H, Bartlam M, Zeng Q, Miyatake H, Hisano T, Miki K, Wong LL, Gao GF and Rao Z (2004) Crystal structure of human Pirin: An iron binding nuclear protein and transcription cofactor. Journal of Biological Chemistry 279 1491-1498
Pang JL, Ricupero DA, Huang S, Fatma N, Singh DP, Romero JR and Chattopadhyay N (2006) Differential activity of kaempferol and quercetin in attenuating tumor necrosis factor receptor family signaling in bone cells. Biochemical Pharmacology 71 818-826
Pang L, Nie M, Corbett L and Knox AJ (2003) Cyclooxygenase-2 expression by nonsteroidal anti-inflammatory drugs in human airway smooth muscle cells: role of peroxisome proliferator-activated receptors. Journal of Immunology 170 1043-1051
Pang M, Martinez AF, Fernandez I, Balkan W and Troen BR (2007) AP-1 stimulates the cathepsin K promoter in RAW 264.7 cells.Gene 403 151-158
Panguluri RC, Long LO, Chen W, Wang S, Coulibaly A, Ukoli F, Jackson A, Weinrich S, Ahaghotu C, Isaacs W and Kittles RA (2004) COX-2 gene promoter haplotypes and prostate cancer risk. Carcinogenesis 25 961-966
Panikashvili D, Mechoulam R, Beni SM, Alexandrovich A and Shohami E (2005) CB(1) cannabinoid receptors are involved in neuroprotection via NF-kB inhibition. Journal of Cerebral Blood Flow and Metabolism 25 477-484
Panikashvili D, Shein NA, Mechoulam R, Trembovler V, Kohen R, Alexandrovich A and Shohami E (2006) The endocannabinoid 2-AG protects the blood-brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines.Neurobiology of Disease 22 257-264
Panne D, Maniatis T and Harrison SC (2004) Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer. EMBO Journal 23 4384-4393
Panne D, Maniatis T and Harrison SC (2007) An atomic model of the interferon-b enhancesome. Cell 129 1111-1123
Pannu R and Singh I (2006) Pharmacological strategies for the regulation of inducible nitric oxide synthase: Neurodegenerative versus neuroprotective mechanisms. Neurochemistry International 49 17-182
Pannu R, Won JS, Khan M, Singh AK and Singh I (2004) A novel role of lactosylceramide in the regulation of lipopolysaccharide/interferon-g-mediated inducible nitric oxide synthase gene expression: implications for neuroinflammatory diseases. Journal of Neuroscience 24 5942-5954
Panopoulos A, Harraz M, Engelhardt JF and Zandi E (2005) Iron-mediated H2O2 production as a mechanism for cell type specific inhibition of TNFa-induced, but not IL-1b-induced IKK/NF-kB activation. Journal of Biological Chemistry 280 2912-2923
Panta GR, Kaur S, Cavin LG, Cortes ML, Mercurio F, Lothstein L, Sweatman TW, Israel M and Arsura M (2004) ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage. Molecular and Cellular Biology 24 1823-1835
Pantano C, Anathy V, Ranjan P, Heintz NH and Janssen-Heininger YM (2007) Nonphagocytic oxidase 1 causes death in lung epithelial cells via a TNF-R1-JNK signaling axis. American Journal of Respiratory Cell and Molecular Biology 36 473-479
Pantoano C, Reynaert NL, Vliet AV and Janssen-Heininger YM (2006) Redox-sensitive kinases of the nuclear factor-kB signaling pathway. Antioxidant and Redox Signaling 8 1791-1806
Pantano C, Shrivastava P, McElhinney B and Janssen-Heininger YM (2003) Hydrogen peroxide signaling through tumor necrosis factor receptor 1 leads to selective activation of C-JUN-N-terminal kinase. Journal of Biological Chemistry 278 44091-44096
Panwalkar A, Verstovsek S and Giles F (2004) Nuclear factor-kB modulation as a therapeutic approach in hematologic malignancies. Cancer 100 1578-1589
Panzer U, Schneider A, Guan Y, Reinking R, Zahner G, Harendza S, Wolf G, Thaiss F and Stahl RA (2002) Effects of different PPARgamma-agonists on MCP-1 expression and monocyte recruitment in experimental glomerulonephritis. Kidney International 62 455-464
Papa S, Bubici C, Pham CG, Zazzeroni F and Franzoso G (2005) NF-kB meets ROS: an ‘iron-ic’ encounter. Cell Death and Differentiation 12 1259-1262
Papa S, Bubici C, Zazzeroni F, Pham CG, Kuntzen C, Knabb JR, Dean K and Franzoso G (2006) The NF-kB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease. Cell Death and Differentiation in press
Papa S, Zazzeroni F, Bubici C, Jayawardena S, Alvarez K, Matsuda S, Nguyen DU, Pham CG, Nelsbach AH, Melis T, Smaele ED, Tang WJ, D’Adamio L and Franzoso G (2004) Gadd45beta mediates the NF-kB suppression of JNK signalling by targeting MKK7/JNKK2. Nature Cell Biology 6 146-163
Papa S, Zazzeroni F, Fu YX, Bubici C, Alvarez K, Dean K, Christiansen PA, Ander RA and Franzoso G (2008) Gadd45beta promotes hepatocyte survival during liver regeneration in mice by modulating JNK signaling. Journal of Clinical Investigation 118 1911-1923
Papa S, Zazzeroni F, Pham CG, Bubici C and Franzoso G (2004) Linking JNK signaling to NF-kB: a key to survival. Journal of Cell Science 117 5197-5208
Papaccio G, Graziano A, d’Aquino R, Valiante S and Naro F (2005) A biphasic role of nuclear transcription factor (NF)-kB in the islet beta-cell apoptosis induced by interleukin (IL)-1beta. Journal of Cell Physiology 204 124-130
Papachritou DJ, Papadakou E, Basdra EK, Baltopoulos P, Panagiotopoulos E and Papvassiliou AG (2008) Involvement of the p38 MAPK-NF-kB signal transduction pathway and COX-2 in the pathobiology of meniscus degeneration in humans. Molecular Medicine14 160-166
Papakonstanti EA and Stournaras C (2004) TNFa promotes survival of OK cells via Cdc42-induced PLC-{gamma}1 activation and actin filament redistribution. Molecular Biology of the Cell 15 1273-1286
Papandreou CN and Logothetis CJ (2004) Bortezomib as a potential treatment for prostate cancer. Cancer Research 64 5036-5043
Papavlassopoulos M, Stamme C, Thon L, Adam D, Hillemann D, Seydel U and Schromm AB (2006) MaxiK blockade selectively inhibits the lipopolysaccharide-induced IkB-a/NF-kB signaling pathway in macrophages. Journal of Immunology 177 4086-4093
Papeleu P, Wullaiert A, Elaut G, Henkens T, Vinken M, Laus G, Tourwe D, Beyaert R, Rogiers V and Vanhaecke T (2007) Inhibition of NF-kB activation by the histone deacetylase inhibitor 4-Me(2)N-BAVAH induces an early G(1) cell cycle arrest in primary hepatocytes. Cell Proliferation 40 961
Papi A and Johnston SL (1999) Respiratory epithelial cell expression of vascular cell adhesion molecule-1 and its up-regulation by rhinovirus infection via NF-kB and GATA transcription factors. Journal of Biological Chemistry 274 30041-30051
Papi A and Johnston SL (1999) Rhinovirus infection induces expression of its own receptor intercellular adhesion molecule 1 (ICAM-1) via increased NF-kB-mediated transcription. Journal of Biological Chemistry 274 9707-9720
Papi A, Papadopoulos NG, Stanciu LA, Bellettato CM, Pinamonti S, Degitz K, Holgate ST and Johnston SL (2002) Reducing agents inhibit rhinovirus-induced up-regulation of the rhinovirus receptor intercellular adhesion molecule-1 (ICAM-1) in respiratory epithelial cells. FASEB Journal 16 1934-1936
Papi A, Papadopoulos NG, Stanciu LA, Degitz K, Holgate ST and Johnston SL (2001) Effect of desloratadine and loratadine on rhinovirus-induced intercellular adhesion molecule 1 upregulation and promoter activation in respiratory epithelial cells. Journal of Allergy and Clinical Immunology 108 221-228
Papouli E, Defais M and Larminat F (2002) Overexpression of metallothionein-II sensitizes rodent cells to apoptosis induced by DNA cross-linking agent through inhibition of NF-kB activation. Journal of Biological Chemistry 277 4764-4769
Papoutsopoulou S, Symons A, Tharmalingham T, Belich MP, Kaiser F, Kioussis D, O’Garra A, Tybulewicz V and Ley SC (2006) ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses. Nature Immunology 7 606-615
Pappu BP and Lin X (2006) Potential role of CARMA1 in CD40-induced splenic B cell proliferation and marginal zone B cell maturation. European Journal of Immunology 36 3033-3043
Paradkar PN and Roth JA (2005) Post-translational and transcriptional regulation of DMT1 during P19 embryonic carcinoma cell differentiation by retinoic acid. Biochemical Journal 394 173-183
Paradkar PN and Roth JA (2006) Nitric oxide transcriptionally down-regulates specific isoforms of divalent metal transporter (DMT1) via NF-kB. Journal of Neurochemistry 96 1768-1777
Paradkar PN and Roth JA (2007) Expression of the 1B isoforms of divalent metal transporter (DMT1) is regulated by interaction of NF-Y with a CCAAT-box element near the transcription start site. Journal of Cellular Physiology 211 183-188
Paradowska A, Maslinski W, Grzybowska-Kowalczyk A and Lacki J (2007) The function of interleukin 17 in the pathogenesis of rheumatoid arthritis. Archivum Immunologiae et Therapiae Experimentalis (Warsz) 55 329-334
Parameswaran N, Pao CS, Leonhard KS, Kang DS, Kratz M, Ley SC and Benovic JL (2006) Arrestin-2 and G protein-coupled receptor kinase 5 interact with NFkB1 p105 and negatively regulate lipopolysaccharide-stimulated ERK1/2 activation in macrophages.Journal of Biological Chemistry 281 34159-34170
Paranjpe A, Cacalano NA, Hume WR and Jewett A (2007) N-acetylcysteine protects dental pulp stromal cells from HEMA-induced apoptosis by inducing differentiation of the cells.
Free Radical Biology and Medicine 43 1394-1408
Parcellier A, Schmitt E, Gurbuxani S, Seigneurin-Berny D, Pance A, Chantome A, Plenchette S, Khochbin S, Solary E and Garrido C (2003) HSP27 is a ubiquitin-binding protein involved in I-kBa proteasomal degradation. Molecular and Cellular Biology 23 5790-5802
Pardanani A, Akin C and Valent P (2006) Pathogenesis, clinical features, and treatment advances in mastocytosis. Best Practice and Research: Clinical Haematology 19 595-615
Pardo A, Barrios R, Maldonado V, Melendez J, Perez J, Ruiz V, Segura-Valdez L, Sznajder JI and Selman M (1998) Gelatinases A and B are up-regulated in rat lungs by subacute hyperoxia: pathogenetic implications. American Journal of Pathology 153 833-844
Pare ME, Gauthier S, Landry S, Sun J, Legault E, Leclerc D, Tanaka Y, Marriott SJ, Tremblay MJ and Barbeau B (2005) A new sensitive and quantitative HTLV-I-mediated cell fusion assay in T cells. Virology 448 309-322
Parekh BS and Maniatis T (1999) Virus infection leads to localized hyperacetylation of histones H3 and H4 at the IFN-b promoter. Molecular Cell 3 125-129
Parhar K, Eivemark S, Assi K, Gomez-Munoz A, Yee A and Salh B (2007) Investigation of interleukin 1beta-mediated regulation of NF-kB activation in colonic cells reveals divergence between PKB and PDK-transduced events. Molecular and CellularBiochemistry 300 113-127
Parhar K, Morse J and Salh B (2007) The role of protein kinase CK2 in intestinal epithelial cell inflammatory signaling.International Journal of Colorectal Disease 22 601-6-0
Parhar K, Ray A, Steinbrecher U, Nelson C and Salh B (2003) The p38 mitogen-activated protein kinase regulates interleukin-1beta-induced IL-8 expression via an effect on the IL-8 promoter in intestinal epithelial cells. Immunology 108 502-512
Paria BC, Bair AM, Xue J, Yu Y, Malik AB and Tiruppathi C (2006) Ca2+ influx-induced by PAR-1 activates a feed-forward mechanism of TRPC1 expression via NF-kB activation in endothelial cells. Journal of Biological Chemistry 281 20715-20727
Paria BC, Malik AB, Kwiatek AM, Rahman A, May MJ, Ghosh S and Tiruppathi C (2003) Tumor necrosis factor-alpha induces nuclear factor-kB-dependent TRPC1 expression in endothelial cells. Journal of Biological Chemistry 278 37195-37203
Parikh AA, Moon MR, Pritts TA, Fischer JE, Szabo C, Hasselgren PO and Salzman AL (2000) IL-1beta induction of NF-kB activation in human intestinal epithelial cells is independent of oxyradical signaling. Shock 13 8-13
Parilla NW, Hughes VS, Lierl KM, Wong HR and Page K (2006) CpG DNA modulates interleukin 1 beta-induced interleukin-8 expression in human bronchial epithelial (16HBE14o-) cells. Respiratory Research 7 84
Paris D, Patel N, Quadros A, Linan M, Bakshi P, Ait-Ghezala G and Mullan M (2007) Inhibition of Abeta production by NF-kB inhibitors. Neuroscience Letters 415 11-16
Paris R, Morales A, Coll O, Sanchez-Reyes A, Garcia-Ruiz C and Fernandez-Checa JC (2002) Ganglioside GD3 sensitizes human hepatoma cells to cancer therapy. Journal of Biological Chemistry 277 49870-49876
Park BK, Zhang H, Zeng Q, Dai J, Keller ET, Giorano T, Gu K, Shah V, Pei L, Zarbo RJ, McCauley L, Shi S, Chen S and Wang CY (2007) NF-kB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF. NatureMedicine 13 62-69
Park C, Lee S, Cho IH, Lee HK, Kim D, Choi SY, Oh SB, Park K, Kim JS and Lee SJ (2005) TLR3-mediated signal induces proinflammatory cytokine and chemokine gene expression in astrocytes: differential signaling mechanisms of TLR3-induced IP-10 and IL-8 gene expression. Glia in press
Park CK, Kim HJ, Kwak HB, Lee TH, Bang MH, Kim CM, Lee Y, Chung DK, Baek NI, Kim J, Lee ZH and Kim HH (2007) Inhibitory effects of Stewartia koreana on osteoclast differentiation and bone resorption. International Immunopharmacology 7 1507-1516
Park CS, Lim H, Han KJ, Baek SH, Sohn HO, Lee DW, Kim YG, Yun HY, Baek KJ and Kwon NS (2004) Inhibition of nitric oxide generation by 23, 24-dihydrocucurbitacin D in mouse peritoneal macrophages. Journal of Pharmacology and Experimental Therapeutics 309 715-710
Park DR, Thomsen AR, Frevert CW, Pham U, Skerrett SJ, Kiener PA and Liles WC (2003) Fas (CD95) induces proinflammatory cytokine responses by human monocytes and monocyte-derived macrophages. Journal of Immunology 170 6209-6216
Park E, Zhu F, Liu B, Xia X, Shen J, Bustos T, Fischer Sm and Hu Y (2007 Reduction in IkB kinase alpha expression promotes the development of skin papillomas and carcinomas. Cancer Research 67 9158-9168
Park EK, Choo MK, Han MJ and Kim DH (2004) Ginsenoside Rh1 possesses antiallergic and anti-inflammatory activities. International Archives of Allergy and Immunology 133 113-120
Park EK, Shin YW, Lee HU, Kim SS, Lee YC, Lee BY and Kim DH (2005) Inhibitory effect of Ginsenoside Rb1 and compound K on NO and prostaglandin E2 biosyntheses of RAW264.7 cells induced by lipopolysaccharide. Biological and Pharmaceutical Bulletin 28 652-656
Park EK, Sung JH, Trinh HT, Bae EA, Yun HK, Hong SS and Kim DH (2008) Lactic acid bacterial fermentation increases the antiallergic effects of Ixeris dentata. Journal of Microbiology and Biotechnology 18 308-313
Park ES, Choi S, Kim JM, Jeong Y, Choe J, Park CS, Choi Y and Rho J (2007) Early embryonic lethality caused by targeted disruption of the TRAF-interacting protein (TRIP) gene. Biochemical and Biophysical Research Communications 363 971-977
Park GY and Christman JW (2006) Nuclear factor kB is a promising therapeutic target in inflammatory lung disease. CurrentDrug Targets 7 661-668
Park GY, Joo M, Pedchenko T, Blackwell TS and Christman JW (2004) Regulation of macrophage cyclooxygenase-2 gene expression by modifications of histone H3. Am J Physiol Lung Cell Mol Physiol 286 L956-L962
Park GY, Le S, Park KH, Le CT, Kim YW, Han SK, Shim YS and Yoo CG (2001) Anti-inflammatory effect of adenovirus-mediated IkBa overexpression in respiratory epithelial cells. European Respiratory Journal 18 801-809
Park GY, Wang X, Hu N, Pedchenko TV, Blackwell TS and Christman JW (2006) NIK is involved in nucleosomal regulation by enhancing histone H3 phosphorylation by IKKa. Journal of Biological Chemistry 281 18684-18690
Park H, Ahn Y, Park CK, Chung HY and Park Y (2003) Interleukin-6 Protects MIN6 beta Cells from Cytokine-Induced Apoptosis. Annals of the New York Academy of Scineces 1005 242-249
Park H, Park SG, Kim J, Ko YG and Kim S (2002) Signaling pahtways for TNF production induced by human aminoacyl-tRNA synthetase-associating factor. Cytokine 20 148-153
Park HH, Lee S, Oh JM, Lee MS, Yoon KH, Park BH, Kim JW, Song H and Kim SH (2006) Anti-inflammatory activity of fisetin in human mast cells (HMC-1). Pharmacological Research in press
Park HJ, Lee HJ, Choi MS, Son DJ, Song HS, Song MJ, Lee JM, Han SB, Kim Y and Hong JT (2008) JNK pathway is involved in the inhibition of inflammatory target gene expression and NF-kB activation by melittin. Journal of Inflaammation (London) 5 7
Park HJ, Chung HJ, Min HY, Park EJ, Hong JY, Kim WB, Kim SH and Lee SK (2005) Inhibitory effect of DA-125, a new anthracyclin analog antitumor agent, on the invasion of human fibrosarcoma cells by down-regulating the matrix metalloproteinases. Biochemical Pharmacology 71 21-31
Park HJ, Kim IT, Won JH, Jeong SH, Park EY, Nam JH, Choi J and Lee KT (2006) Anti-inflammatory activities of ent-16alphaH,17-hydroxy-kauran-19-oic acid isolated from the roots of Siegesbeckia pubescens are due to the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via NF-kB inactivation. European Journal of Pharmacology 558 185-193
Park HJ, Lee SH, Son DJ, Oh KW, Kim KH, Song HS, Kim GJ, Oh GT, Yoon DY and Hong JT (2004) Antiarthritic effect of bee venom: Inhibition of inflammation mediator generation by suppression of NF-kB through interaction with the p50 subunit. Arthritis and Rheumatism 50 3504-3515
Park HJ, Lee YW and Lee SK (2004) Baicalin induces NAD(P)H:quinone reductase through the transactivation of AP-1 and NF-kB in Hepa 1c1c7 cells. European Journal of Cancer Prevention 13 521-528
Park HJ, Park OJ and Shin J (2005) Receptor activator of NF-kB ligand enhances the activity of macrophages as antigen presenting cells. Experimental and Molecular Medicine 37 524-532
Park HJ, Son DJ, Lee CW, Choi MS, Lee US, Song HS, Lee JM and Hong JT (2006) Melittin inhibits inflammatory target gene expression and mediator generation via interaction with IkB kinase. Biochemical Pharmacology 73 237-247
Park HS, Jung HY, Park EY, Kim J, Lee WJ and Bae YS (2004) Direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF-kB. Journal of Immunology 173 3589-3593
Park J, Choe SS, Choi AH, Kim KH, Yoon MJ, Suganami T, Ogawa Y and Kim JB (2006) Increase in glucose-6-phosphate dehydrogenase in adipocytes stimulates oxidative stress and inflammatory signals. Diabetes 55 2939-2949
Park J, Choi K, Jeong E, Kwon D, Benveniste EN and Choi C (2004) Reactive oxygen species mediate chloroquine-induced expression of chemokines by human astroglial cells. Glia 47 9-20
Park J, Jung Y, Kim J, Kim KY, Ahn SG, Song K and Lee I (2007) TC1 (C8orf4) is upregulated by cellular stress and mediates heat shock response. Biochemical and Biophysical Research Communications 360 447-452
Park J, Kim M, Na G, Jeon I, Kwon YK, Kim JH, Youn H and Koo Y (2007) Glucocorticoids modulates NF-kB-dependent gene expression by up-regulating FKBP51 expression in Newcastle disease virus-infected chickens. Molecular and CellularEndocrinology 278 7-17
Park J, Lee JH, La M, Jang MJ, Chae GW, Kim SB, Tak H, Jung Y, Byun B, Ahn JK and Joe CO (2007) Inhibition of NF-kB acetylation and its transcriptional activity by Daxx. Journal of Molecular Biology 368 388-397
Park JE, Kim YI and Yi AK (2008) Protein kinase D1: a new component in TLR9 signaling. Journal of Immunology 181 2044-2055
Park JH and Faller DV (2002) Epstein-Barr virus latent membrane protein-1 induction by histone deacetylase inhibitors mediates induction of intercellular adhesion molecule-1 expression and homotypic aggregation. Virology 303 345-363
Park JH, Lee CK, Hwang YS, Park KK and Chung WY (2008) Hemin inhibits cyclooxygenase-2 expression through nuclear factor-kappa B activation and ornithine decarboxylase expression in 12-O-tetradecanoylphorbol-13-acetate-treated mouse skin. Mutation Research in press
Park JH and Levitt L (1993) Overexpression of mitogen-activated protein kinase (ERK1) enhances T-cell cytokine gene expression: role of AP1, NF-AT, and NF-kB. Blood 82 2470-2477
Park JH, Liu L, Kim IH, Kim JH, You KR and Kim DG (2005) Identification of the genes involved in enhanced fenretinide-induced apoptosis by parthenolide in human hepatoma cells. Cancer Research 65 2804-2814
Park JK, Fiebeler A, Muller DN, Mervaala EM, Dechend R, Abou-Rebyeh F, Luft FC and Haller H (2002) Lacidipine inhibits adhesion molecule and oxidase expression independent of blood pressure reduction in angiotensin-induced vascular injury. Hypertension 39 685-689
Park JI, Lee MG, Cho K, Park BJ, Chae KS, Byun DS, Ryu BK, Park YK and Chi SG (2003) Transforming growth factor-beta1 activates interleukin-6 expression in prostate cancer cells through the synergistic collaboration of the Smad2, p38-NF-kB, JNK, and Ras signaling pathways. Oncogene 22 4314-4332
Park JM, Brady H, Ruocco MG, Sun H, Williams D, Lee SJ, Kato T Jr, Richards N, Chan K, Mercurio F, Karin M and Wasserman SA (2004) Targeting of TAK1 by the NF-kB protein Relish regulates the JNK-mediated immune response in Drosophila. Genes & Development 18 584-594
Park JM, Greten FR, Li ZW and Karin M (2002) Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition. Science 297 2048-2051
Park JM, Greten FR, Wong A, Westrick RJ, Arthur JS, Otsu K, Hoffman A, Montminy M and Karin M (2005) Signaling pathways and genes that inhibit pathogen-induced macrophage apoptosis- CREB and NF-kB as key regulators. Immunity 23 319-329
Park JM, Kim A, Oh JH and Chung AS (2007) Methylseleninic acid inhibits PMA-stimulated pro-MMP-2 activation mediated by MT1-MMP expression and further tumor invasion through suppression of NF-kB activation. Carcinogenesis 212 386-400
Park JM, Kim JM, Kim LK, Kim SN, Kim-Ha J, Kim JH and Kim YJ (2003) Signal-induced transcriptional activation by Dif requires the dTRAP80 mediator module. Molecular and Cellular Biology 23 1358-1367
Park JS, Arcaroli J, Yum HK, Yang H, Wang H, Yang KY, Choe KH, Strassheim D, Pitts TM, Tracey KJ and Abraham E (2003) Activation of gene expression in human neutrophils by high mobility group box 1 protein. American Journal of Physiology: Cell Physiology 284 C870-C879
Park JS, Gamboni-Robertson F, He Q, Svetkauskaite D, Kim JY, Strassheim D, Sohn JW, Yamada S, Maruyama I, Banerjee A, Ishizaka A and Abraham E (2005) High Mobility Group Box 1 protein (HMGB1) interacts with multiple Toll like receptors.American Journal of Physiology: Cell Physiology 290 C917-C924
Park JS, Jung SH, Seo H and Kim HS (2007) SB203580 enhances interleukin-1 receptor antagonist gene expression in IFN-gamma-stimulated BV2 microglial cells through a composite nuclear factor-kB/PU.1 binding site. Neuroscience Letters 416 169-174
Park JS, Lee EJ, Lee JC, Kim WK and Kim HS (2007) Anti-inflammatory effects of short chain fatty acids in IFN-g-stimulated RAW 264.7 murine macrophage cells: Involvement of NF-k+B and ERK signaling pathways. International Immunopharmacology 7 70-77
Park JS, Onodera T, Nishimura SI, Thompson RF and Itohara S (2006) Molecular evidence for two-stage learning and partial laterality in eyeblink conditioning of mice. Proceedings of the National Academy of Sciences USA 103 5549-5554
Park JS, Svetkauskaite D, He Q, Kim JY, Strassheim D, Ishizaka A and Abraham E (2004) Involvement of TLR 2 and TLR 4 in cellular activation by high mobility group box 1 protein (HMGB1). Journal of Biological Chemistry 279 7370-7377
Park JS, Woo MS, Kim DH, Hyun JW, Kim WK, Lee JC and Kim HS (2007) Anti-inflammatory mechanisms of isoflavone metabolites in lipopolysaccharide-stimulated microglial cells. Journal of Pharmacology and Experimental Therapeutics 320 1237-1245
Park JS, Woo MS, Kim SY, Kim WK and Kim HS (2005) Repression of interferon-gamma-induced inducible nitric oxide synthase (iNOS) gene expression in microglia by sodium butyrate is mediated through specific inhibition of ERK signaling pathways. Journal of Neuroimmunology 168 56-64
Park JW, Qi WN, Cai Y, Urbaniak JR and Chen LE (2007) Proteasome inhibitor attenuates skeletal muscle reperfusion injury by blocking the pathway of nuclear factor-kB activation. Plastic and Reconstructive Surgery 120 1808-1818
Park JY, Chang JH, Bae KS, Lee KH, Choi SJ, Park JY, Ryang YS, Kim SK (2008) NF-kB-dependency and consequent regulation of IL-8 in echinomycine-induced apoptosis of HT-29 colon cancer cells. Cell Biology International 32 1207-1214
Park JY, Kawada T, Han IS, Kim BS, Goto T, Takahashi N, Fushiki T, Kurata T and Yu R (2004) Capsaicin inhibits the production of tumor necrosis factor alpha by LPS-stimulated murine macrophages, RAW 264.7: a PPARgamma ligand-like action as a novel mechanism. FEBS Letters 572 266-270
Park JY, Kim YM, Song HS, Park KY, Kim YM, Seon Kim M, Pak YK, Lee IK, Lee JD, Park SJ and Lee KU (2003) Oleic acid induces endothelin-1 expression through activation of protein kinase C and NF-kB. Biochemical and Biophysical Research Communications 303 891-895
Park KA, Byun HS, Won M, Yang KJ, Shin S, Piao L, Kim JM, Woon WH, Junn E, Park J, Seok JH and Hur GM (2006) Sustained activation of protein kinase C down-regulates nuclear factor-kB signaling by dissociation of IKK-g and Hsp90 complex in human colonic epithelial cells. Carcinogenesis in press
Park KG, Lee KM, Chang YC, Magae J, ANdo K, Kim KB, Kim YN, Kim HS, Park JY, Lee KU and Lee IK (2006) The ascochlorin derivative, AS-6, inhibits TNF-a-induced adhesion molecule and chemokine expression in rat vascular smooth muscle cells. Life Sciences 80 120-126
Park KJ, Choi SH, Choi DH, Park JM, Yie SW, Lee SY and Hwang SB (2003) Hepatitis C virus NS5A protein modulates c-Jun N-terminal kinase through interaction with TNF receptor-associated factor 2. Journal of Biological Chemistry 278 30711-30718
Park KJ, Gaynor RB and Kwak YT (2003) Hsp27 association with the IKK complex regulates TNF-alpha-induced NF-kB activation. Journal of Biological Chemistry 278 35272-35278
Park K-J, Krishnan V, O’Malley BW, Yamamoto Y and Gaynor RB (2005) Formation of an IKKa-dependent transcription complex is required for estrogen receptor-mediated gene activation. Molecular Cell 18 71-82
Park KR, Lee JH, Choi C, Liu KH, Seog DH, Kim YH, KIm DE, Yun CH and Yea SS (2007) Suppression of interleukin-2 gene expression by isoeugenol is mediated through down-regulation of NF-AT and NF-kB.
International Immunopharmacology 7 1251-1258
Park KS, Kim MK, Im DS and Bae YS (2007) Effect of lysophosphatidylglycerol on several signaling molecules in OVCAR-3 human ovarian cancer cells: Involvement of pertussis toxin-sensitive G-protein coupled receptor. Biochemical Pharmacology 73 675-681
Park KS and Chang IM (2004) Anti-inflammatory activity of aucubin by inhibition of tumor necrosis factor-alpha production in RAW 264.7 cells. Planta Medica 70 778-779
Park LJ, Ju SM, Song HY, Lee JA, Yang MY, Kang YH, Kwon HJ, Kim TY, Choi SY and Park J (2006) The enhanced monocyte adhesiveness after UVB exposure requires ROS and NF-kB signaling in human keratinocyte. Journal of Biochemistry and Molecular Biology 39 618-625
Park M, Yong Y, Choi SW, Kim JH, Lee JE and Kim DW (2007) Constitutive RelA activation mediated by Nkx3.2 controls chondrocyte viability. Nature Cell Biology 9 287-298
Park MA and Kim HJ (2007) Anti-inflammatory constituents isolated from Clerodendron trichotomum Tunberg Leaves (CTL) inhibits pro-inflammatory gene expression in LPS-stimulated RAW 264.7 macrophages by suppressing NF-kB activation. Archives ofPharmacal Research 30 755-760
Park MH, Song HS, Kim KH, Son DJ, Lee SH, Yoon DY, Kim Y, Park IY, Song S, Hwang BY, Jung JK and Hong JT (2005) Cobrotoxin inhibits NF-kB activation and target gene expression through reaction with NF-kB signal molecules. Biochemistry 44 8326-8336
Park MJ, Lee JY, Kwak HJ, Park CM, Lee HC, Woo SH, Jin HO, Han CJ, An S, Lee SH, Chung HY, Park IC, Hong SI and Rhee CH (2005) Arsenic trioxide (As(2)O(3)) inhibits invasion of HT1080 human fibrosarcoma cells: Role of nuclear factor-kappaB and reactive oxygen species. Journal of Cellular Biochemsitry 95 955-969
Park MY, Jang HD, Lee SY, Lee KJ and Kim E (2004) Fas associated factor 1 inhibits NF-kB activity by interfering with nuclear translocation of RelA (p65) subunit of NF-kB. Journal of Biological Chemistry 279 2544-2549
Park M-Y, Moon J-h, Lee K-S, Choi H-I, Chung J, Hong HJ and Kim E (2007) FAF1 suppresses IKK activation by disrupting the IKK complex assembly. Journal of Biological Chemistry 282 27572-27577
Park S, Ahn ES, Han DW, Lee JH, Min KT, Kim H and Hong YW (2008) Pregabalin and gabapentin inhibit substance P-induced NF-kB activation in neuroblastoma and glioma cells. Journal of Cellular Biochemistry in press
Park S, Dong B and Matsumura F (2007) Rapid acitvation of c-Src kinase by dioxin is mediated by the Cdc37-HSP90 complex as part of Ah receptor signaling in MCF10A cells. Biochemistry 46 899-908
Park S and James CD (2005) ECop (EGFR-Coamplified and overexpressed protein), a novel protein, regulates NF-kB transcriptional activity and associated apoptotic response in an IkBa-dependent manner. Oncogene 24 2495-2502
Park S, Ramnarain DB, Hatanpaa KJ, Mickey BE, Saha D, Paulmurugan R, Madden CJ, Wright PS, Bhai S, Ali MA, Puttapharthi K, Hu W, Elliott JL, Stuve O and Habib AA (2008) The death domain-containing kinase RIP1 regulates p27(Kip1) levels through the PI3K-Akt-forkhead pathway. EMBO Reports in press
Park S, Yeo M, Jin JH, Lee KM, Jung JY, Choue R, Cho SW and Hahm KB (2005) Rescue of Helicobacter pylori-induced cytotoxicity by red ginseng. Digestive Diseases and Sciences 50 1218-1227
Park S, Yeo M, Jin JH, Lee KM, Kim SS, Choi SY and Hahm KB (2007) Inhibitory activities and attenuated expressions of 5-LOX with red ginseng in Helicobacter pylori-infected gastric epithelial cells. Digestive Diseases and Sciences 52 973-982
Park SG, Chung C, Kang H, Kim Jy and Jung G (2006) Up-regulation of cyclin D1 by HBx is mediated by NF-kB2/BCL3 complex through kB site of cyclin D1 promoter. Journal of Biological Chemistry 281 31770-31777
Park SG, Lee T, Kang HY, Park K, Cho KH and Jung G (2006) The influence of the signal dynamics of activated form of IKK on NF-kB and anti-apoptotic gene expressions: a systems biology approach. FEBS Letters 580 822-830
Park SG, Lee DY, Seo SK, Lee SW, Kim SK, Jung WK, Kang MS, Choi YH, Yea SS, Choi I and Choi IW (2008) Evaluation of anti-allergic properties of caffeic acid phenethyl ester in a murine model of systemic anaphylaxis. Toxicology and Appled Pharmacology 226 22-29
Park SG, Ryu HM, Lim SO, Kim YI, Hwang SB and Jung G (2005) Interferon-gamma inhibits Hepatitis B Virus-induced NF-kB activation through nuclear localization of NF-kB-inducing kinase. Gastroenterology 128 2042-2053
Park SH, Choi WS, Yoon SY, Ahn YS and Oh YJ (2004) Activation of NF-kB is involved in 6-hydroxydopamine-but not MPP(+)-induced dopaminergic neuronal cell death: its potential role as a survival determinant. Biochemical and Biophysical Research Communicaitons 322 727-733
Park SH, Kim KE, Hwang HY and Kim TY (2003) Regulatory effect of SOCS on NF-kB Activity in murine monocytes/macrophages. DNA Cell Biology 22 131-139
Park SH, Park JH, Kang JS and Kang YH (2003) Involvement of transcription factors in plasma HDL protection against TNF-alpha-induced vascular cell adhesion molecule-1 expression. International Journal of Biochemistry & Cell Biology 35 168-182
Park SJ, Lee SC, Hong SH and Kim HM (2002) Degradation of IkBa in activated RAW264.7 cells is blocked by the phosphatidylinositol 3-kinase inhibitor LY294002. Cell Biol Toxicol 18 121-130
Park SK, Yang WS, Han NJ, Lee SK, Ahn H, Lee IK, Park JY, Lee KU and Lee JD (2004) Dexamethasone regulates AP-1 to repress TNF-a induced MCP-1 production in human glomerular endothelial cells. Nephrology, Dialysis and Transplantation 19 312-319
Park SW, Huq MD, Hu X and Wei LN (2005) Tyrosine nitration on p65: a novel mechanism to rapidly inactivate NF-kB. Molecular and Cellular Proteomics 4 300-309
Park SM, Park HY and Lee TH (2003) Functional effects of TNF-a on a human follicular dendritic cell line: persistent NF-kB activation and sensitization for Fas-mediated apoptosis. Journal of Immunology 171 3955-3962
Park SM, Yoon JB and Lee TH (2004) Receptor interacting protein is ubiquitinated by cellular inhibitor of apoptosis proteins (c-IAP1 and c-IAP2) in vitro. FEBS Letters 566 151-156
Park SS, Kim JM, Kim DS, Kim IH and Kim SY (2006) Transglutaminase 2 mediates polymer formation of I-kBa through C-terminal glutamine cluster. Journal of Biological Chemistry in press
Park SW and Wei LN (2003) Regulation of c-myc gene by nitric oxide via inactivating NF-kB complex in P19 mouse embryonal carcinoma cellsD. Journal of Biological Chemistry 278 29776-29782
Park SY, Lee JH, Kim CD, Lee WS, Park WS, Han J, Kwak YG, Kim KY and Hong KW (2006) Cilostazol suppresses superoxide production and expression of adhesion molecules in human endothelial cells via mediation of cAMP-dependent protein kinase-mediated maxi-K channel activation. Journal of Pharmacology and Experimental Therapeutics 317 1238-1245
Park SY, Lee JH, Kim YK, Kim CD, Rhim BY, Lee WS and Hong KW (2005) Cilostazol prevents remnant lipoprotein particle-induced monocyte adhesion to endothelial cells by suppression of adhesion molecules and MCP-1 E expression via LOX-1 receptor activation. Journal of Pharmacology and Experimental Therapeutics 312 1241-1248
Park W, Lim W, Choi J, Inoue H, Rhyu MR and Lee Y (2006) Inhibitory effects of ginsenoside-rb1 on activation of the 12-O-tetradecanoylphorbol 13-acetate-induced cyclooxygenase-2 promoter. Planta Medica 72 272-275
Park WI, Park MJ, An JK, Choi YH, Kim HY, Cheong J and Yang US (2008) Bile acid regulates c-Jun expression through the orphan nuclear receptor SHP induction in gastric cells. Biochemical and Biophysical Research Communications 369 437-443
Park WY, Hwang CI, Im CN, Kang MJ, Woo JH, Kim JH, Kim YS, Kim JH, Kim H, Kim KA, Yu HJ, Lee SJ, Lee YS and Seo JS (2002) Identification of radiation-specific responses from gene expression profile. Oncogene 21 8521-8528
Park Y (2007) Functional evaluation of the type 1 diabetes (T1D) susceptibility candidate genes.
Diabetes Research and Clinical Practice 77 S110-S115
Park YC, Rimbach G, Saliou C, Valacchi G and Packer L (2000) Activity of monomeric, dimeric, and trimeric flavonoids on NO production, TNF-a secretion, and NF-kB-dependent gene expression in RAW 264.7 macrophages. FEBS Letters 465 93-97
Park YK, Chung YS, Kim YS, Kwon OY and Joh TH (2007) Inhibition of gene expression and production of iNOS and TNF-alpha in LPS-stimulated microglia by methanol extract of Phellodendri cortex. International Immunopharmacology 7 955-962
Park YM, Kim IT, Park HJ, Choi JW, Park KY, Lee JD, Nam BH, Kim DG, Lee JY and Lee KT (2004) Anti-inflammatory and anti-nociceptive effects of the methanol extract of Fomes fomentarius. Biol Pharm Bull 27 1588-1593
Park YM, Won JH, Kim YH, Choi JW, Park HJ and Lee KT (2005) In vivo and in vitro anti-inflammatory and anti-nociceptive effects of the methanol extract of Inonotus obliquus. Journal of Ethnopharmacology 101 120-128
Park YM, Won JH, Yun KJ, Ryu JH, Han YN, Choi SK and Lee KT (2006) Preventive effect of ginkgo biloba extract (GBB) on the lipopolysaccharide-induced expressions of inducible nitric oxide synthase and cyclooxygenase-2 via suppression of nuclear factor-kB in RAW 264.7 cells.
Biol Pharm Bull 29 985-990
Parkash J (2008) Inflammatory cytokine signaling in insulin producing beta-cells enhances the colocalization correlation coefficient between L-type voltage-dependent calcium channel and calcium-sensing receptor. International Journal of Molecular Medicine 22 155-163
Parker A, Izmailova ES, Narang J, Badola S, Le T, Roubenoff R, Ginsburg GS, Maier A, Coblyn Jr JS, Shadick NA and Weinblatt ME (2007) Peripheral blood expression of nuclear factor-kB-regulated genes is associated with rheumatoid arthritis disease activity and responds differentially to anti-tumor necrosis factor-a versus methotrexate. Journal of Rheumatology 34 1817-1822
Parker K, Ma M, Manyak S, Altamirano C, Tang Y, Frantzen M, Mikail A, Roussos E, Sjak-Shie N, Vescio R and Berenson J (2002) Identification of polymorphisms of the IkBa gene associated with an increased risk of multiple myeloma. Cancer Genetics and Cytogenetics 137 43-48
Parker LC, Whyte MK, Vogel SN, Dower SK and Sabroe I (2004) Toll-like receptor (TLR)2 and TLR4 agonists regulate CCR expression in human monocytic Cells. Journal of Immunology 172 4977-4985
Parker SF, Felzien LK, Perkins ND, Imperiale MJ and Nabel GJ (1997) Distinct domains of adenovirus E1A interact with specific cellular factors to differentially modulate human immunodeficiency virus transcription. Journal of Virology 71 2004-2012
Parnet P, Pousset F and Laye S (2003) NFkB activation in mouse pituitary: comparison of response to interleukin-1beta and lipopolysaccharide. Journal of Neuroendocrinology 15 304-314
Parodi FE, Mao D, Ennis TL, Bartoli MA and Thompson RW (2005) Suppression of experimental abdominal aortic aneurysms in mice by treatment with pyrrolidine dithiocarbamate, an antioxidant inhibitor of nuclear factor-kB. Journal of Vascular Surgery 41 479-489
Parodi FE, Mao D, Ennis TL, Pagano MB and Thompson RW (2006) Oral administration of diferuloylmethane (curcumin) suppresses proinflammatory cytokines and destructive connective tissue remodeling in experimental abdominal aortic aneurysms. Annals ofVascular Surgery 20 360-368
Parra E, Varga M, Sigvardsson H, Hedlund G, Kalland T, Leanderson T, Sjogren HO and Dohlsten M (1995) Costimulation of human CD4+ T cells with LFA-3 and B7 induces distinct effects on AP-1 and NF-kB transcription factors. Journal of Immunology 155 1132-1140
Parrami F, Fang ZT, Fogelman AM, Andalibi A, Territo MC and Berliner JA (1993) Minimally modified low density lipoprotein-induced inflammatory responses in endothelial cells are mediated by cyclic adenosine monophosphate. Journal of Clinical Investigation 92 471-478
Parreira R, Piedade J, Domingues A, Labao D, Santos M, Venenno T, Baptista JL, Mussa SA, Barreto AT, Baptista AJ and Esteves A (2006) Genetic characterization of human immunodeficiency virus type 1 from Beira, Mozambique. Microbes and Infection 8 2442-2451
Parris GE (2007) Mechanism and history of evolution of symbiotic HIV strains into lethal pandemic strains: the key event may have been a 1927 trial of pamaquine in Leopoldville (Kinshasa), Congo. Medical Hypotheses 69 838-848
Parrish WR, Rosas-Ballina M, Ballowitsch-Puerta M, Ochani M, Ochani K, Hudson LQ, Lin X, Patel N, Johnson SM, Chavan S, Goldstein R, Czura CJ, Miller EJ, Al-Abed Y, Tracey KJ and Pavlov VA (2008) Modulation of TNF release by choline requires alpha7 subunit nicotinic acetylcholine receptor-mediated signaling. Molecular Medicine in press
Parrott C, Seidner T, Duh E et al (1991) Variable role of the long terminal repeat Sp1-binding sites in human immunodeficiency virus replication in T lymphocytes. Journal of Virology 65 1414-1419
Parrott JN and Gay NJ (1998) Expression and subcellular distribution of rel/NF kB transcription factors in the preimplantation mouse embryo: novel kB binding activities in the blastocyst stage embryo. Zygote 6 249-260
Parry GC and Mackman N (1994) A set of inducible genes expressed by activated human monocytic and endothelial cells contain kB-like sites that specifically bind c-Rel-p65 heterodimers. Journal of Biological Chemistry 269 20823-20825
Parry RV, Whittaker GC, Sims M, Edmead CE, Welham MJ and Ward SG (2006) Ligation of CD28 stimulates the formation of a multimeric signaling complex involving grb-2-associated binder 2 (gab2), SRC homology phosphatase-2, and phosphatidylinositol 3-kinase: evidence that negative regulation of CD28 signaling requires the gab2 pleckstrin homology domain. Journal ofImmunology 176 594-602
Parsonage G, Giler A, Bik M, Hardie D, Lax S, Howlett K, Church LD, Raza K, Wong SH, Trebilcock E, Scheel-Toellner D, Salmon M, Lord JM and Buckley CD (2008) Prolonged, granulocyte-macrophage-colony stimulating factor dependent, neutrophil survival following rheumatoid synovial fibroblast activation by IL-17 and TNF-a. Arthritis Research and Therapy 10 R47
Parsons MJ and Vertino PM (2006) Dual role of TMS1/ASC in death receptor signaling. Oncogene 25 6948-6958
Parsons SA and Greer PA (2006) The Fps/Fes kinase regulates the inflammatory response to endotoxin through down-regulation of TLR4, NF-kB activation, and TNF-a secretion in macrophages. Journal of Leukocyte Biology 80 1522-1528
Partin JV, Anglin IE and Kyprianou N (2003) Quinazoline-based alpha1-adrenoceptor antagonists induce prostate cancer cell apoptosis via TGF-beta signalling and IkBa induction. British Journal of Cancer 88 1615-1621
Partridge J, Carlsen H, Enesa K, Chaudhury H, Zakkar M, Luong L, Kinderlerer A, Johns M, Blomhoff R, Mason JC, Haskard Do and Evans PC (2007) Laminar shear stress acts as a switch to regulate divergent functions of NF-kB in endothelial cells. FASEB Journal 21 3553-3561
Pascal V, Nathan NR, Claudio E, Siebenlist U and Anderson SK (2007) NF-kB p50/p65 affects the frequency of Ly49 gene expression by NK cells. Journal of Immunology 179 1751-1759
Pascual G and Glass CK (2006) Nuclear receptors versus inflammation: mechanisms of transrepression. Trends in Endocrinology and Metabolism 17 321-327
Pascual G, Fong AL, Ogawa S, Gamliel A, Li AC, Perissi V, Rose DW, Willson TM, Rosenfeld MG and Glass CK (2005) A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma. Nature 437 759-763
Pascual G, Sullivan AL, Ogawa S, Gamliel A, Perissi V, Rosenfield MG and Glass CK (2007) Anti-inflammatory and antidiabetic roles of PPARgamma. Novartis Foundation Symposium 286 183-196
Pascussi JM, Dvorak Z, Gerbal-Chaloin S, Assenat E, Maurel P and Vilarem MJ (2003) Pathophysiological factors affecting CAR gene expression. Drug Metabolism Reviews 35 255-268
Pashkow FJ, Watumull DG and Campbell CL (2008) Astaxanthin: a novel potential treatment for oxidative stress and inflammation in cardiovascular disease. American Journal of Caridology 101 58D-68D
Pasparakis M, Courtois G, Hafner M, Schmidt-Supprian M, Nenci A, Toksoy A, Krampert M, Goebeler M, Gillitzer R, Israel A, Krieg T, Rajewsky K and Haase I (2002) TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2. Nature 411 861-866
Pasparakis M, Luedde T and Schmidt-Supprian M (2006) Dissection of the NF-kB signalling cascade in transgenic and knockout mice. Cell Death and Differentiation 13 861-872
Pasparakis M, Schmidt-Supprian M and Rajewsky K (2002) IkB Kinase signaling is essential for maintenance of mature B cells. Journal of Experimental Medicine 196 743-752
Pasquini LA, Besio Moreno M, Lopez Salon M and Soto EF (2002) Apoptosis in Schwann cell cultures is closely interrelated with the activity of the ubiquitin-proteasome proteolytic pathway. Neurochem Research 27 1401-1419
Passerini AG, Polacek DC, Shi C, Francesco NM, Manduchi E, Grant GR, Pritchard WF, Powell S, Chang GY, Stoeckert CJ Jr and Davies PF (2004) Coexisting proinflammatory and antioxidative endothelial transcription profiles in a disturbed flow region of the adult porcine aorta. Proceedings of the National Academy of Sciences USA 101 2482-2487
Passos GF, Fernandes ES, Campos MM, Araujo JG, Pesquero JL, Souza GE, Avellar MC, Teixeira MM and Calixto JB (2004) Kinin B(1) receptor up-regulation after lipopolysaccharide administration: role of proinflammatory cytokines and neutrophil influx. Journal of Immunology 172 1839-1847
Pastva A, Estell K, Schoeb TR and Schwiebert LM (2005) RU486 blocks the anti-inflammatory effects of exercise in a murine model of allergen-induced pulmonary inflammation. Brain Behav Immun 19 413-422
Pastva A, Estell K, Schoeb TR, Atkinson TP and Schwiebert LM (2004) Aerobic exercise attenuates airway inflammatory responses in a mouse model of atopic asthma. Journal of Immunology 172 4520-4526
Paszek P, Lipniacki T, Brasier AR, Tian B, Nowak DE and Kimmel M (2005) Stochastic effects of multiple regulators on expression profiles in eukaryotes. Journal of Theoretical Biology 233 423-433
Paszt A, Eder K, Szaboks A, Tiszlavicz L, Lazar G, Duda E, Takacs T and Lazar Jr G (2008) Effects of glucocorticoid agonist and antagonist on the pathogenesis of L-arginine-induced acute pancreatitis in rat. Pancreas 46 369-376
Patel A, Hanson J, McLean TI, Olgiate J, Hilton M, Miller WE and Bachenheimer SL (1998) Herpes simplex virus type 1 induction of persistent NF-kB nuclear translocation increases the efficiency of virus replication. Virology 247 212-222
Patel A, Miller L, Ahmed K and Ondrey F (2004) NF-kB downregulation strategies in head and neck cancer treatment. Otolaryngol Head and Neck Surgery 131 288-295
Patel C, Ghanim H, Ravishankar S, Sia CL, Viswanathan P, Mohanty P and Dandona P (2007) Prolonged reactive oxygen species generation and nuclear factor-kB activation following a high fat high carbohydrate meal in the obese. Journal of ClinicalEndocrinology and Metabolism 92 4476-4479
Patel D, Huang SM, Baglia LA and McCance DJ (1999) The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300. EMBO Journal 18 5061-5072
Patel DN, Bailey SR, Gresham JK, Schuchman DB, Shelhamer JH, Goldstein BJ, Foxwell BM, Stemerman MB, Maranchie JK, Valente AJ, Mummidi S and Chandrasekar B (2006) TLR4-NOX4-AP-1 signaling mediates lipopolysaccharide-induced CXCR6 expression in human aortic smooth muscle cells. Biochemical and Biophysical Research Communications 347 1113-1120
Patel JR and Brewer GJ (2008) Age-related differences in NFkB translocation and Bcl-2/Bax ratio caused by TNFa and Ab42 promote survival in middle-age neurons and death in old neurons. Experimental Neurology in press
Patel KM, Wright KL, WHittaker P, Chakravarty P, Watson ML and Ward SG (2005) Differential modulation of COX-2 expression in A549 airway epithelial cells by structurally distinct PPARg agonists: evidence for disparate functional effects which are independent of NF-kB and PPARg. Cell Signal 17 1098-1110
Patel NM, Nozaki S, Shortle NH, Bhat-Nakshatri P, Newton TR, Rice S, Gelfanov V, Boswell SH, Goulet RJ, Jr., Sledge GW, Jr. and Nakshatri H (2000) Paclitaxel sensitivity of breast cancer cells with constitutively active NF-kB is enhanced by IkBa super-repressor and parthenolide. Oncogene 19 4159-4169
Patel NR, Zhu J, Tachado SD, Zhang J, Wan Z, Saukkonen J and Koziel H (2007) HIV impairs TNF-alpha mediated macrophage apoptotic response to Mycobacterium tuberculosis. Journal of Immunology 179 6983-6980
Patel PS, Varney ML, Dave BJ and Singh RK (2002) Regulation of constitutive and induced NF-kB activation in malignant melanoma cells by capsaicin modulates interleukin-8 production and cell proliferation. Journal of Interferon and Cytokine Research 22 427-435
Patel PS, Yang S, Li A, Varney ML and Singh RK (2002) Capsaicin regulates vascular endothelial cell growth factor expression by modulation of hypoxia inducing factor-1alpha in human malignant melanoma cells. Journal of Cancer Research and Clinical Oncology 128 461-468
Patel R, Atherton P, Wackerhage H and Singh J (2006) Signaling proteins associated with diabetic-induced exocrine pancreatic insufficiency in rats. Annals of the New York Academy of Sciences 1084 490-502
Patel S, Leal AD and Gorski DH (2005) The homeobox gene Gax inhibits angiogenesis through inhibition of nuclear factor-kB-dependent endothelial cell gene expression. Cancer Research 65 1414-1424
Patel SK, Ma N, Monks TJ and Lau SS (2003) Changes in gene expression during chemical-induced nephrocarcinogenicity in the Eker rat. Molecular Carcinogenesis 38 141-154
Patel VI, Daniel S, Longo CR, Shrikhande GV, Scali ST, Czismadia E, Groft CM, Shukri T, Motley-Dore C, Ramsey HE, Fisher MD, Grey ST, Arvelo MB and Ferran C (2006) A20, a modulator of smooth muscle cell proliferation and apoptosis, prevents and induces regression of neointimal hyperplasia. FASEB Journal 20 1418-1430
Paterson RL, Galley HF, Dhillon JK and Webster NR (2000) Increased nuclear factor kB activation in critically ill patients who die. Critical Care Medicine 28 1047-1051
Paterson RL, Galley HF and Webster NR (2003) The effect of N-acetylcysteine on nuclear factor-kB activation, interleukin-6, interleukin-8, and intercellular adhesion molecule-1 expression in patients with sepsis. Critical Care Medicine 31 2574-2578
Pathak SK, Basu S, Basu KK, Banerjee A<Pathak S, Bhattacharyya A, Kaisho T, Kundu M and Basu J (2007) Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages. Nature Immunology in press
Pathak SK, Basu S, Bhattacharyya A, Banerjee A, Basu J and Kundu M (2006) TLR4-dependent NF-kB activation and mitogen- and stress-activated protein kinase 1-triggered phosphorylation events are central to Helicobacter pylori peptidyl prolyl cis-, trans-isomerase (HP0175)-mediated induction of IL-6 release from macrophages. Journal of Immunology 177 7950-7958
Pathak SK, Basu S, Bhattacharyya A, Pathak S, Kundu M and Basu J (2005) Mycobacterium tuberculosis lipoarabinomannan-mediated IRAK-M induction negatively regulates toll-like receptor-dependent interleukin-12 p40 production in macrophages. Journal of Biological Chemistry 280 42794-42800
Pathak SK, Bhattacharyya A, Pathak S, Basak C, Mandal D, Kundu M and Basu J (2004) Toll-like receptor 2 and mitogen and stress-activated kinase 1 are effectors of Mycobacterium-avium induced cyclooxygenase-2 expression in macrophages. Journal of Biological Chemistry 279 55127-55136
Pathmanathan S, Krishna MT, Blomberg A, Helleday R, Kelly FJ, Sandstrom T, Holgate ST, Wilson SJ and Frew AJ (2003) Repeated daily exposure to 2 ppm nitrogen dioxide upregulates the expression of IL-5, IL-10, IL-13, and ICAM-1 in the bronchial epithelium of healthy human airways. Occup Environ Med 60 892-896
Pati S, Cavrois M, Guo HG, Foulke JS, Jr., Kim J, Feldman RA and Reitz M (2001) Activation of NF-kB by the human herpesvirus 8 chemokine receptor ORF74: evidence for a paracrine model of Kaposi’s sarcoma pathogenesis. Journal of Virology 75 8660-8673
Pati S, Foulke JS Jr, Barabitskaya O, Kim J, Nair BC, Hone D, Smart J, Feldman RA, Reitz M (2003) Human Herpesvirus 8-encoded vGPCR activates nuclear factor of activated T cells and collaborates with human immunodeficiency virus Type 1 Tat. Journal of Virology 77 5759-5773
Patil CS and Kirkwood KL (2007) p38 MAPK signaling in oral-related diseases. Journal of Dental Research 86 812-825
Patke A, Mecklenbrauker I and Tarakhovsky A (2004) Survival signaling in resting B cells. Current Opinion in Immunology 16 251-255
Patra AK, Na SY and Bommhardt U (2004) Active protein kinase B regulates TCR responsiveness by modulating cytoplasmic-nuclear localization of NFAT and NF-kB proteins. Journal of Immunology 172 4812-4820
Patrizio M (2004) Tumor necrosis factor reduces cAMP production in rat microglia. Glia 48 241
Patrizio M, Colucci M and Levi G (2001) Human immunodeficiency virus type 1 Tat protein decreases cyclic AMP synthesis in rat microglia cultures. Journal of Neurochemistry 77 399-407
Patrone JB, Bish SE and Stein DC (2006) TNF-a-independent IL-8 expression: alterations in bacterial challenge dose cause differential human monocytic cytokine response. Journal of Immunology 177 1314-1322
Pattacini L, Casali B, Boiardi L, Pipitone N, Albertazzi L and Salvarani C (2007) Angiotensin II protects fibroblast-like synoviocytes from apoptosis via the AT1-NF-kB pathway. Rheumatology (Oxford) 46 1252-1257
Patten EJ and DeLong MJ (1999) Temporal effects of the detoxification enzyme inducer, benzyl isothiocyanate: activation of c-Jun N-terminal kinase prior to the transcription factors AP-1 and NFkB. Biochemical and Biophysical Research Communications 257 149-155
Patterson RM, Stachlewitz R and Germolec D (2003) Induction of apoptosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin following endotoxin exposure. Toxicolology and Applied Pharmacology 190 120-134
Pattoli MA, Macmaster JF, Gregor KR and Burke J (2005) Collagen and Agrecan degradation is blocked in interleukin-1-treated cartilage explants by an inhibitor of IkB kinase through suppression of metalloproteinase expression. Journal of Pharmacology and Experimental Therapeutics 315 382-388
Paukkeri EL, Leppanen T, Sareila O, Vuolteenaho K, Kankaanranta H and Moilanen E (2007) PPARalpha agonists inhibit nitric oxide production by enhancing iNOS degradation in LPS-treated macrophages. British Journal of Pharmacology 152 1081-1091
Paul NL, Lenardo MJ, Novak KD, Sarr T, Tang W-L and Ruddle NH (1990) Lymphotoxin activation by human T-cell leukemia virus type I-infected cell lines: role for NF-kB. Journal of Virology 64 5412-5419
Paul SC, Lv P, Xiao YJ, An P, Liu SQ and Luo HS (2006) Thalidomide in rat liver cirrhosis: blockade of tumor necrosis factor-a via inhibition of degradation of an inhibitor of nuclear factor-kB. Pathobiology 73 82-92
Paule B, Terry S, Kheuang L, Soyeux P, Vacherot F and de la Taille A (2007) The NF-kB/IL-6 pathway in metastatic androgen-independent prostate cancer: new therapeutic approaches? World Journal of Urology 25 477-489
Pauleau AL and Murray PJ (2003) Role of nod2 in the response of macrophages to toll-like receptor agonists. Molecular and Cellular Biology 23 7531-7539
Pauley E, Linderkamp O and Poschi J (2005) Incontinentia pigmenti in combination with decreased IgG subclass concentrations in a female newborn. Biology of the Neonate 88 172-174
Paulino N, Abreu SR, Uto Y, Koyama D, Nagasawa H, Hori H, Dirsch VM, Vollmar AM, Scremin A and Bretz WA (2008) Anti-inflammatory effects of a bioavailable compound, Artepillin C, in Brazilian propolis. European Journal of Pharmacology 587 296-301
Paulino N, Teixeira C, Martins R, Scremin A, Disch VM, Vollmar AM, Abreu SR, De Castro SL and Marcucci MC (2006) Evaluation of the analgesic and anti-inflammatory effects of a Brazilian green propolis. Planta Medica 72 899-906
Paulmann D< Magulski T, Schwarz R, Heitmann L, Flehmig B, Vallbracht A and Dotzauer A (2008) Hepatitis A virus protein 2B suppresses beta interferon (IFN) gene transcription by interfering with IFN regulatory factor 3 activation. Journal of General Virology 89 1593-1604
Paulmurugan R, Massoud TF, Huang J and Gambhir SS (2004) Molecular imaging of drug-modulated protein-protein interactions in living subjects. Cancer Research 64 2113-2119
Paumelle R, Blanquart C, Briand O, Barbier O, Duhem C, Woerly G, Percevault F, Fruchart JC, Dombrowicz D, Glineur C and Staels B (2006) Acute antiinflammatory properties of statins Involve peroxisome proliferator-activated receptor-a via inhibition of the protein kinase C Signaling pathway. Circulation Research 98 361-369
Paun A, Reinert JT, Jiang Z , Medin C, Balkhi MY, Fitzgerald KA and Pitha PM (2008) Functional characterization of murine interferon regulatory factor 5 (IRF-5) and its role int he innate antiviral response. Journal of Biolgocal Chemistry 283 14295-14308
Paunesku T, Chang-Liu CM, Shearin-Jones P, Watson C, Milton J, Oryhon J, Salbego D, Milosavljevic A and Woloschak GE (2000) Identification of genes regulated by UV/salicylic acid. International Journal of Radiation Biology 76 189-198
Paur I, Austenaa LM and Blomhoff R (2008) Extracts of dietary plants are efficient modulators of nuclear factor kappa B. Food and Chemical Toxicology 46 1288-1297
Pausawasdi N, Ramamoorthy S, Crofford LJ, Askari FK and Todisco A (2002) Regulation and function of COX-2 gene expression in isolated gastric parietal cells. Am J Physiol Gastrointest Liver Physiol 282 G1069-G1078
Pawate S, Shen Q, Fan F and Bhat NR (2004) Redox regulation of glial inflammatory response to lipopolysaccharide and interferongamma. Journal of Neuroscience Research 77 540-551
Paxian S, Liptay S, Adler G, Hameister H and Schmid RM (1999) Genomic organization and chromosomal mapping of mouse nuclear factor kB2 (NFKB2). Immunogenetics 49 743-750
Paxian S, Merkle H, Riemann M, Wilda M, Adler G, Hameister H, Liptay S, Pfeffer K and Schmid RM (2002) Abnormal organogenesis of Peyer’s patches in mice deficient for NF-kB1, NF-kB2, and Bcl-3. Gastroenterology 122 1853-1868
Paxton LLL, Li L-J, Secor V, Duff JL, Naik SM, Shibagaki N and Caughman SW (1997) Flanking sequences for the human cellular adhesion molecule-1 NF-kB response element are necessary for tumor necrosis factor a-induced gene expression. Journal of Biological Chemistry 272 15928-15935
Paya CV, Ten RM, Bessia C, Alcami J, Hay RT and Virelizier J-L (1992) NF-?B-dependent induction of the NF-kB p50 subunit gene promoter underlies self-perpetuation of human immunodeficiency virus transcription in monocytic cells. Proceedings of the National Academy of Sciences USA 89 7826-7830
Payne CM, Crowley C, Washo-Stultz D, Briehl M, Bernstein H, Bernstein C, Beard S, Holubec H and Warneke J (1998) The stress-response proteins poly(ADP-ribose) polymerase and NF-kB protect against bile salt-induced apoptosis. Cell Death & Differentiation 5 623-636
Payne DN and Adcock IM (2001) Molecular mechanisms of corticosteroid actions. Paediatr Respir Rev 2 145-150
Payne TM, Molestina RE and Sinai AP (2003) Inhibition of caspase activation and a requirement for NF-kB function in the Toxoplasma gondii-mediated blockade of host apoptosis. Journal of Cell Science 116 4345-4358
Payvandi F, Wu L, Naziruddin SD, Haley M, Parton A, Schafer PH, Chen RS, Muller GW, Huges CC and Stirling DI (2005) Immunomodulatory drugs (IMiDs) increase the production of IL-2 from stimulated T cells by increasing PKC-theta activation and enhancing the DNA-binding activity of AP-1 but not NF-kB, OCT-1, or NF-AT. Journal of Interferon and Cytokine Research 25 604-616
Paz-Priel I, Cai DH, Wang D, Kowalski J, Blackford A, Liu H, Heckman CA, Gombart AF, Koeffler HP, Boxer LM and Friedman AD (2005) CCAAT/enhancer binding protein alpha (C/EBPa) and C/EBPa myeloid oncoproteins induce Bcl-2 via interaction of their basic regions with nuclear factor-kB p50. Molecular Cancer Research 3 585-596
Pazdernik NJ, Donner DB, Goebl MG and Harrington MA (1999) Mouse receptor interacting protein 3 does not contain a caspase-recruiting or a death domain but induces apoptosis and activates NF-kB. Molecular and Cellular Biology 19 6500-6508
Pazdrak K, Shi XZ and Sarna SK (2004) TNFa suppresses human colonic circular smooth muscle cell contractility by SP1- and NF-kB-mediated induction of ICAM-1. Gastroenterology 127 1096-1109
Pazin MJ, Sheridan PL, Cannon K, Cao Z, Keck JG, Kadanoga JT and Jones KA (1996) NF-kB-mediated chromatin reconfiguration and transcriptional activation of the HIV-1 enhancer in vitro. Genes & Development 10 37-49
Pearl JM, Schwartz SM, Nelson DP, Wagner CJ, Lyons JM, Bauer SM and Duffy JY (2004) Preoperative glucocorticoids decrease pulmonary hypertension in piglets after cardiopulmonary bypass and circulatory arrest. Annals of Thoracic Surgery 77 994-1000
Pearlstein DP, Ali MH, Mungai PT, Hynes KL, Gewertz BL and Schumacker PT (2002) Role of mitochondrial oxidant generation in endothelial cell responses to hypoxia. Arterioscler Thromb Vasc Biol 22 566-573
Pechanova O, Jendekova L, Kojsova S and Jagla F (2006) Possible role of nitric oxide in the locomotor activity of hypertensive rats. Behavior Brain Research in press
Pechanova O, Zicha J, Kojsova S, Dobesova Z, Jendekova L and Kunes J (2005) The effect of chronic N-acetylcysteine treatment on the development of spontaneous hypertension. Clinical Sciences 110 235-242
Pechanova O, Zicha J, Paulis L, Zenebe W, Dobesova Z, Kojsova S, Jendekova L, Sladkova M, Dovinova I, Simko F and Kunes J (2007) The effect of N-acetylcysteine and melatonin in adult spontaneously hypertensive rats with established hypertension.European Journal of Pharmacology 26 1577-1585
Pechkovsky DV, Scaffidi AK, Hackett TL, Ballard J, Shaheen F, Thompson PJ, Thannickal VJ and Knight DA (2008) TGFbeta 1 induces alpha vbeta 3 integrin expression in human lung fibroblasts via a beta 3 integrin, c-Src and p38MAPK dependent pathway. Journal of Biological Chemistry in press
Pecquet C, Nyga R, Penard-Lacronique V, Smithgall TE, Murakami H, Regnier A, Lassoued K and Goulleux F (2006) The Src tyrosine kinase Hck is required for Tel-Abl- but not for Tel-Jak2-induced cell transformation. Oncogene in press
Pedersen KB, Andersen K, Fodstad O and Maelandsmo GM (2004) Sensitization of interferon-gamma induced apoptosis in human osteosarcoma cells by extracellular S100A4. BMC Cancer 4 52
Pedra JH, Sukumaran B, Carlyon JA, Berliner N and Fikrig E (2005) Modulation of NB4 promyelocytic leukemic cell machinery by Anaplasma phagocytophilum. Genomics 86 365-377
Pedro de Magalhaes J, Chainiaux F, de Longueville F, Mainfroid V, Migeot V, Marcq L, Remacle J, Salmon M and Toussaint O (2004) Gene expression and regulation in H(2)O(2)-induced premature senescence of human foreskin fibroblasts expressing or not telomerase. Experimental Gerontology 39 1379-1389
Peebles KA, Lee JM, Mao JT, Hazra S, Reckamp KL, Krysan K, Dohadwala M, Heinrich EL, Walser TC, Cui X, Baratelli FE, Garon E, Sharma S and Dubinett SM (2007) Inflammation and lung carcinogenesis: applying findings in prevention and treatment. Expert Review of Anticancer Therapy 7 1405-1421
Peel AL (2004) PKR activation in neurodegenerative disease. Journal of Neuropathology and Experimental Neurology 63 97-105
Peet GW and Li J (1999) IkB kinases a and b show a random sequential kinetic mechanism and are inhibited by staurosporine and quercetin. Journal of Biological Chemistry 274 32655-32661
Pegg AE (2008) Spermidine/spermine-N1-acetyltransferase; a key metabolic regulator. American Journal of Physiology, Endocrinology & Metabolism in press
Pegman PM, Smith SM, D’Souza BN, Loughran ST, Maier S, Kempkes B, Cahill PA, Simmons MJ, Gelinas C and Walls D (2006) Epstein-Barr virus nuclear antigen 2 trans-activates the cellular antiapoptotic bfl-1 gene by a CBF1/RBPJk-dependent pathway.Journal of Virology 80 8133-8144
Peh SC, Gan GG, Lee LK and Eow GI (2008) Clinical relevance of CD10, BCL-6 and multiple myeloma-1 expression in diffuse large B-ell lymphomas in Malaysia. Pathology International 58 572-579
Pei DS, Fu Y, Sun YF, Hu SQ, Zhou H, Lu L and Zhao HR (2005) Cys(74) and Cys(163) are necessary for IL-18 to elicit IFN-gamma production from peripheral blood lymphoid mononuclear cells. Molecular Immunology 42 1367-1373
Pei J, Turse JE and Ficht TA (2008) Evidence of Brucella abortus OPS dictating uptake and restricting NF-kB activation in murine macrophages. Microbes and Infection in press
Pei L, Castrillo A and Tontonoz P (2005) Regulation of macrophage inflammatory gene expression by the orphan nuclear receptor Nur77. Molecular Endocrinology 20 786-794
Pei XH, Nakanishi Y, Inoue H, Takayama K, Bai F and Hara N (2002) Polycyclic aromatic hydorcarbons induce IL-8 expression through nuclear factor kB activation in A549 cell line. Cytokine 19 236-241
Pei XH, Nakanishi Y, Takayama K, Bai F and Hara N (1999) Benzo[a]pyrene activates the human p53 gene through induction of nuclear factor kB activity. Journal of Biological Chemistry 274 35240-35246
Pei XY, Dai Y and Grant S (2004) Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors. Clinical Cancer Research 10 3839-3852
Peiris M (2006) Pathogenesis of avian flu H5N1 and SARS. Novartis Foundation Symposium 279 56-60
Peiro C, Matesanz N, Nevado J, Lafuente N, Cercas E, Azcutia V, Vallejo S, Rodriguez-Manas L, Sanchez-Ferrer CF (2003) Glycosylated human oxyhaemoglobin activates nuclear factor-kB and activator protein-1 in cultured human aortic smooth muscle. British Journal of Pharmacology 140 681-690
Peiser M, Koeck J, Kirschring CJ, Wittig B and Wanner R (2008) Human Langerhans cells selectively activated via Toll-like receptor 2 agonists acquire migratory and CD4+T cell stimulatory capacity. Journal of Leukocyte Biology in press
Pekar O, Molotski N, Savion S, Fein A, Toder V and Torchinsky A (2007) p53 regulates cyclophosphamide teratogenesis by controlling caspases 3, 8, 9 activation and NF-kB DNA binding. Reproduction 134 379-388
Pelayo R, Hirose J, Huang J, Garrett KP, Delogu A, Busslinger M and Kincade PW (2005) Derivation of two categories of plasmacytoid dendritic cells in murine bone marrow. Blood 105 4407-4415
Pellacani A, Chin MT, Wiesel P, Ibanez M, Patel A, Yet SF, Hsieh CM, Paulauskis JD, Reeves R, Lee ME and Perrella MA (1999) Induction of high mobility group-I(Y) protein by endotoxin and interleukin-1beta in vascular smooth muscle cells. Role in activation of inducible nitric oxide synthase. Journal of Biological Chemistry 274 1525-1532
Pellegatta F, Bertelli AA, Staels B, Duhem C, Fulgenzi A and Ferrero ME (2003) Different short- and long-term effects of resveratrol on nuclear factor-kB phosphorylation and nuclear appearance in human endothelial cells. American Journal of Clinical Nutrition 77 1220-1228
Pelletier C, Varin-Blank N, Rivera J, Iannascoli B, Marchand F, David B, Weyer A and Blank U (1998) Fc epsilonRI-mediated induction of TNF-a gene expression in the RBL-2H3 mast cell line: regulation by a novel NF-kB-like nuclear binding complex. Journal of Immunology 161 4768-4776
Pelletier JP, Fernandes JC, Jovanovic DV, Reboul P and Martel-Pelletier J (2001) Chondrocyte death in experimental osteoarthritis is mediated by MEK 1/2 and p38 pathways: role of cyclooxygenase-2 and inducible nitric oxide synthase. Journal of Rheumatology 28 2509-2519
Pelletier M and Girard D (2006) Differential effects of IL-15 and IL-21 in myeloid (CD11b+) and lymphoid (CD11b-) bone marrow cells. Journal of Immunology 177 100-108
Peloponese Jr JM and Jeang KT (2006) Role for Akt/protein kinase B and AP-1 in cellular proliferation induced by the human T-cell leukemia virus type 1 (HTLV-1) Tax oncoprotein. Journal of Biological Chemistry 281 8927-8938
Peloponese JM, Yeung ML and Jeang KT (2006) Modulation of nuclear factor-kB by human T cell leukemia virus type 1 Tax protein: implications for oncogenesis and inflammation. Immunologic Research 34 1-12
Pelosi L, Giacinti C, Nardis C, Borsellino G, Rizzuto E, Nicoletti C, Wannenes F, Battistini L, Rosenthal N, Molinaro M and Musaro A (2007) Local expression of IGF-1 accelerates muscle regeneration by rapidly modulating inflammatory cytokines and chemokines. FASEB Journal in press
Peltier J, Bellocq A, Perez J, Doublier S, Dubois YC, Haymann JP, Camussi G and Baud L (2006) Calpain activation and secretion promote glomerular injury in experimental glomerulonephritis: evidence from calpastatin-transgenic mice. Journal of the American Society of Nephrology in press
Pelzer T, Neumann M, de Jager T, Jazbutyte V and Neyses L (2001) Estrogen effects in the myocardium: inhibition of NF-kB DNA binding by estrogen receptor-alpha and -beta. Biochemical and Biophysical Research Communications 286 1153-1157
Pelzer T, Schumann M, Neumann M, deJager T, Stimpel M, Serfling E and Neyses L (2000) 17beta-estradiol prevents programmed cell death in cardiac myocytes. Biochemical and Biophysical Research Communications 268 192-200
Penas EM, Kawadler H, Siebert T, Frank M, Ye H, Hinz K, Becher C, Hummel M, Barth TF, Bokemeyer C, Stein H, Trumper L, MOller P, Marynen P, Du MQ, Yang X, Hansmann ML and Dierlamm J (2006) A novel fusion of the MALT1 gene and the microtubule-associated protein 4 (MAP4) gene occurs in diffuse large B-cell lymphoma. Genes, Chromosomes and Cancer in press
Penc SF, Pomahac B, Eriksson E, Detmar M and Gallo RL (1999) Dermatan sulfate activates nuclear factor-kappab and induces endothelial and circulating intercellular adhesion molecule-1. Journal of Clinical Investigation 103 1329-1335
Pendurthi UR, Meng F, Mackman N and Rao LV (2002) Mechanism of resveratrol-mediated suppression of tissue factor gene expression. Thrombosis and Haemostosis 87 155-162
Peng CY, Pan SL, Huang YW, Guh JH, Chang YL and Teng CM (2008) Baicalein attenuates intimal hyperplasia after rat carotid balloon injury through arresting cell-cycle progression and inhibiting ERK, Akt, and NF-kB activity in vascular smooth-muscle cells. Naunyn Schmiedebergs Arch Pharmacol in press
Peng G, Dixon DA, Muga SJ, Smith TJ and Wargovich MJ (2006) Green tea polyphenol (-)-epigallocatechin-3-gallate inhibits cyclooxygenase-2 expression in colon carcinogenesis. Molecular Carcinogenesis 45 309-319
Peng G, Zhang F, Zhang Q, Wu K, Zhu F and Wu J (2007) Borna disease virus P protein inhibits nitric oxide synthase gene expression in astrocytes. Virology 46 676-679
Peng H, tan L, Osaki M, Zhan Y, Ijiri K, Tsuchimochi K, Otero M, Wang H, Choy BK, Grall FT, Gu X, Libermann TA, Oettgen P and Goldring MB (2007) ESE-1 is a potent repressor of type II collagen gene (COL2A1) transcription in human chondrocytes. Journal of Cellular Physiology in press
Peng H-B, Libby P and Liao JK (1995) Induction and stabilization of IkBa by nitric oxide mediates inhibition of NF-kB. Journal of Biological Chemistry 270 14214-14219
Peng HH, Liang S, Henderson AJ and Dong C (2006) Regulation of interleukin-8 expression in melanoma-stimulated neutrophil inflammatory response. Experimental Cell Research in press
Peng JH, Hu YY, Cheng Y, Han C, Xu LL, Feng Q, Chen SD, Tao Q, Li HS and Li XM (2008) Effect of JIANPI HUOXUE decoction on inflammatory cytokine secretion pathway in rat liver with lipopolysaccharide challenge. World Journal of Gastroenterology 14 1851-1857
Peng PL, Hsieh YS, Wang CJ, Hsu JL and Chou FP (2005) Inhibitory effect of berberine on the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2. Toxicology and AppliedPharmacology in press
Peng SL (2004) Transcription factors in the pathogenesis of autoimmunity. Clinical Immunology 110 112-123
Peng SL (2005) Interplay between the NF-kB and forkhead transcription factors.Cell Death & Differentiation 12 699-701
Peng SL (2008) Transcription factors in autoimmune diseases. Frontiers in Biosciences 13 4218-4240
Peng T, Kotla S, Bumgarner RE and Gustin KE (2006) Human rhinovirus attenuates the type I interferon response by disrupting activation of interferon regulatory factor 3. Journal of Virology 80 5021-5031
Peng T, Lu X and Feng Q (2005) NADH oxidase signaling induces cyclooxygenase-2 expression during lipopolysaccharide stimulation in cardiomyocytes. FASEB Journal 19 293-295
Peng X, Zhang P, Wang X, Chan J, Jiang M, Tuthill C, Wan Y, Dragoi AM and Chu WM (2007) Signaling pathways leading to the activation of IKK and MAPK by thymosin alpha 1. Annals of the New York Acad Sciences in press
Peng Y, Gallagher SF, Haines K, Baksh K and Murr MM (2005) Nuclear factor-kB mediates Kupffer cell apoptosis through transcriptional activation of Fas/FasL. Journal of Surgical Research in press
Peng Y, Gallagher SF, Landmann R, Haines K and Murr MM (2006) The role of p65 NF-kB/RelA in pancreatitis-induced Kupffer cell apoptosis. Journal of Gastrointestinal Surgery 10 837-847
Peng Y, Gong JP, Liu CA, Li SW, Gan L and Li SB (2005) The effect of glycine on CD14 and NF-kB in Kupffer cells from rat liver grafts after ischemia-reperfusion injury [Article in Chinese]. Zhonghua Gan Zang Bing Za Zhi 13 179-182
Peng Y, Kwok KH, Yang PH, Ng SS, Liu J, Wong OG, He ML, Kung HF and Lin MC (2005) Ascorbic acid inhibits ROS production, NF-kB activation and prevents ethanol-induced growth retardation and microencephaly. Neuropharmacology 48 426-434
Peng Y, Liu ZJ, Gong JP, Liu HZ, Gan L and Li SB (2005) Expression of CD14 and Toll-like receptor 4 on Kupffer cells and its role in ischemia-reperfusion injury on rat liver graft [Article in Chinese]. Zhonghua Wai Ke Za Zhi 43 274-276
Peng Y and Murr MM (2007) Establishment of immortalized rat Kupffer cell lines. Cytokine in press
Peng Y, Power MR, Li B and Lin TJ (2005) Inhibition of IKK down-regulates antigen + IgE-induced TNF production by mast cells: a role for the IKK-IkB-NF-kB pathway in IgE-dependent mast cell activation. Journal of Leukocyte Biology 77 975-983
Peng Y, Sigua CA, Gallagher SF and Murr MM (2007) Protein kinase C-z is critical in pancreatitis-induced apoptosis of Kupffer cells. Journal of Gastrointestinal Surgery 11 1712-1721
Peng Y, Sigua CA, Karsonovich C and Murr MM (2007) Protein kinase C-zeta (PKC-z) regulates Kupffer cell apoptosis during experimental sepsis. Journal of Gastrointestinal Surgery in press
Peng Y, Sigua CA, Rideout D and Murr MM (2008) Deletion of Toll-like receptor-4 downregulates protein kinase C-zeta and attenuates liver injury in experimental pancreatitis. Surgery 143 679-685
Peng Z, Peng L, Fan Y, Zandi E, Shertzer HG and Xia Y (2007) A critical role for IKKb in metallotheionein-1 expression and protection against arsenic toxicity. Journal of Biological Chemistry 282 21487-21496
Peng Z, Zhang Y, Gu W, Wang Z, Li D, Zhang F, Qiu G and Xie K (2005) Integration of the hepatitis B virus X fragment in hepatocellular carcinoma and its effects on the expression of multiple molecules: A key to the cell cycle and apoptosis. International Journal of Oncology 26 467-473
Pengelley SC, Chapman DC, Mark Abbott W, Lin HH, Huang W, Dalton K and Jones IM (2006) Reishi polysaccharides induce immunoglobulin production through the TLR4/TLR2-mediated induction of transcription factor Blimp-1. Journal of BiologicalChemistry in press
Penner CG, Gang G, Wray C, Fischer JE and Hasselgren PO (2001) The transcription factors NF-kappab and AP-1 are differentially regulated in skeletal muscle during sepsis. Biochemical and Biophysical Research Communications 281 1331-1336
Penido C, Costa KA, Costa MF, de Pereira JF, Siani AC and Henriques MG (2006) Inhibition of allergen-induced eosinophil recruitment by natural tetranortriterpenoids is mediated by the suppression of IL-5, CCL11/eotaxin and NFkB activation.International Immunopharmacology 6 109-121
Penna G, Amuchastegui S, Giarratana N, Daniel KC, Vulcano M, Sozzani S and Adorini L (2007) 1,25-dihydroxyvitamin d3 selectively modulates tolerogenic properties in myeloid but not plasmacytoid dendritic cells. Journal of Immunology 178 145-153
Pennington C, Dunn J, Li C, Ha T and Browder W (2000) Nuclear factor kB activation in acute appendicitis: a molecular marker for extent of disease? American Surgery 66 914-918
Pennington K, Taylor J, Bren G and Paya C (2001) IkB kinase-dependant chronic activation of NF-kB is necessary for p21WAF1/Cip1 inhibition of differentiation-induced apoptosis of monocytes. Molecular and Cellular Biology 21 1930-1941
Pennington KN, Taylor JA, Bren GD and Paya CV (2001) IkB kinase-dependent chronic activation of NF-kB is necessary for p21(WAF1/Cip1) inhibition of differentiation-induced apoptosis of monocytes. Molecular and Cellular Biology 21 1930-1941
Penninkhof F, Grootegoed JA and Blok LJ (2004) Identification of REPS2 as a putative modulator of NF-kB activity in prostate cancer cells. Oncogene 23 5607-5615
Pennisi E (1997) Superoxides relay Ras protein’s oncogenic message. Science 275 1567-1568
Pennypacker KR, Kassed CA, Eidizadeh S, Saporta S, Sanberg PR (2001) Willing AE (2001) NF-kB p50 is increased in neurons surviving hippocampal injury. Exp Neurol 172 307-319
Penolazzi L, Borgatti M, Lambertini E, Mischiati C, Finotti A, Romanelli A, Saviano M, Pedone C, Piva R and Gambari R (2004) Peptide nucleic acid-DNA decoy chimeras targeting NF-kB transcription factors: Induction of apoptosis in human primary osteoclasts. International Journal of Molecular Medicine 14 145-152
Penolazzi L, Lambertini E, Borgatti M, Piva R, Cozzani M, Giovannini I, Naccari R, Siciliani G and Gambari R (2003) Decoy oligodeoxynucleotides targeting NF-kB transcription factors: induction of apoptosis in human primary osteoclasts. Biochemical Pharmacology 66 1189-1198
Penolazzi L, Maagri E, Lambertini E, Calo G, Cozzani M, Siciliani G, Piva R and Gambari R (2006) Local in vivo administration of a decoy oligonucleotide targeting NF-kB induces apoptosis of osteoclasts after application of orthodontic forces to rat teeth. International Journal of Molecular Medicine 18 807-811
Pentikainen V, Suomalainen L, Erkkila K, Martelin E, Parvinen M, Pentikainen MO and Dunkel L (2002) Nuclear factor-kB activation in human testicular apoptosis. American Journal of Pathology 160 205-218
Penttinen MA, Holmberg CI, Sistonen L and Granfors K (2002) HLA-B27 modulates nuclear factor kB activation in human monocytic cells exposed to lipopolysaccharide. Arthritis Rheum 46 2172-2180
Pepin N, Roulston A, Lacoste J, Lin R and Hiscott J (1994) Subcellular redistribution of HTLV-I Tax protein by NF-kB/Rel transcription factors. Virology 204 706-716
Pepperl S, Dorger M, Ringel F, Kupatt C and Krombach F (2001) Hyperoxia upregulates the NO pathway in alveolar macrophages in vitro: role of AP-1 and NF-kB. American Journal of Physiology Lung Cell Mol Physiol 280 L905-L913
Percario ZA, Giandomenico V, Fiorucci G, Chiantore MV, Vannucchi S, Hiscott J, Affabris E and Romeo G (1999) Retinoic acid is able to induce interferon regulatory factor 1 in squamous carcinoma cells via a STAT-1 independent signalling pathway. Cell Growth & Differentiation 10 263-270
Perchonock CE, Fernando MC, Quinn 3rd WJ, Nguyen CT, Sun J, Shapiro MJ and Shapiro VS (2006) Negative regulation of interleukin-2 and p38 mitogen-activated protein kinase during T-cell activation by the adaptor ALX. Molecular and Cellular Biology 26 6005-6015
Pereda J, Escobar J, Sandoval J, Rodriguez JL, Sabater L, Pallardo FV, Torres L, Franco L, Vina J, Lopez-Rodas G and Sastre J (2008) Glutamate cysteine ligase up-regulation fails in necrotizing pancreatitis. Free Radical Biology and Medicine in press
Pereda J, Sabater L, Aparisi L, Escobar J, Sandoval J, Vina J, Lopez-Rodas G and Sastre J (2006) Interaction between cytokines and oxidative stress in acute pancreatitis. Current Medicinal Chemistry 13 2775-2787
Perera PY, Mayadas TN, Takeuchi O, Akira S, Zaks-Zilberman M, Goyert SM and Vogel SN (2001) CD11b/CD18 acts in concert with CD14 and Toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression. Journal of Immunology 166 574-581
Pereira MP, Hurtado O, Cardenas A, Alonso-Escolano D, Bosca L, Vivancos J, Nombela F, Leza JC, Lorenzo P, Lizasoain I and Moro MA (2005) The nonthiazolidinedione PPARg agonist L-796,449 is neuroprotective in experimental stroke. Journal of Neuropathology and Experimental Neurology 64 797-805
Pereira MP, Hurtado O, Cardenas A, Bosca L, Castillo J, Davalos A, Vivancos J, Serena J, Lorenzo P Lizasoain I and Moro MA (2005) Rosiglitazone and 15-deoxy-Delta(12,14)-prostaglandin J(2) cause potent neuroprotection after experimental stroke through noncompletely overlapping mechanisms.
Journal of Cerebral Blood Flow and Metabolism 26 218-229
Pereira SG and Oakley F (2007) Nuclear factor-kB1: Regulation and function. International Journal of Biochemistry and Cell Biology in press
Perez A and Davis PB (2004) Gene profile changes after Pseudomonas aeruginosa exposure in immortalized airway epithelial cells. Journal of Structural and Functional Genomics 5 179-194
Perez A, Issler AC, Cotton CU, Kelley TJ, Verkman AS and Davis PB (2006) CFTR inhibition mimics the cystic fibrosis inflammatory profile. American Journal of Physiology: Lung Cell and Molecular Physiology in press
Perez D and White E (2003) E1A sensitizes cells to tumor necrosis factor alpha by downregulating c-FLIP(S). Journal of Virology 77 2651-2662
Perez JR, Higgins-Sochaski AH, Maltese J-Y and Narayanan R (1994) Regulation of adhesion and growth of fibrosarcoma cells by NF-kB RelA involves transforming growth factor b. Molecular and Cellular Biology 14 5326-5332
Perez JR, Li Y, Stein CA, Majumder S, van Oorschot A and Narayanan R (1994) Sequence independent induction of Sp1 transcription factor by phosphorothioate oligodeoxynucleotides. Proceedings of the National Academy of Sciences USA 91 5957-5961
Perez M, Haschke B and Donato NJ (1999) Differential expression and translocation of protein tyrosine phosphatase 1B-related proteins in ME-180 tumor cells expressing apoptotic sensitivity and resistance to tumor necrosis factor: potential interaction with epidermal growth factor receptor. Oncogene 18 967-978
Perez P, Lira SA and Bravo R (1995) Overexpression of RelA in transgenic mouse thymocytes: specific increase in levels of the inhibitor protein IkBa. Molecular and Cellular Biology 15 3523-3530
Perez P, Page A and Jorcano JL (2000) Role of phosphorylated p50-NF-kB in the ultraviolet response of mouse skin. Molecular Carcinogenesis 27 272-279
Perez P, Page A, Bravo A, Del Rio M, Gimenez-Conti I, Budunova I, Slaga TJ and Jorcano JL (2001) Altered skin development and impaired proliferative and inflammatory responses in transgenic mice overexpressing the glucocorticoid receptor. FASEB Journal 15 2030-2032
Perez-de-Arce K, Foncea R and Leighton F (2005) Reactive oxygen species mediates homocysteine-induced mitochondrial biogenesis in human endothelial cells: Modulation by antioxidants. Biochemical and Biophysical Research Communications 338 1103-1109
Perez-Martinez FC, Alonso V, Sarasa JL, Manzarbeitia F, Vela-Navarrete R, Calahorra FJ and Esbrit P (2008) Receptor activator of nuclear factor-kB ligand (RANKL) as a novel prognostic marker in prostate carcinoma. Histology and Histopathology 23 709-715
Perez-Martinez FC, Alonso V, Sarasa JL, Nam-Cha SG, Vela-Navarrete R, Manzarbeitia F, Calahorra FJ and Esbrit P (2007) Immunohistochemical analysis of low-grade and high-grade prostate carcinoma: relative changes of pthrp and its pth1 receptor, osteoprotegerin and receptor activator of nuclear factor-kb ligand. Journal of Clinical Pathology 60 290-294
Perez-Martinez P, Lopez-Miranda J, Blanco-Colio L, Bellido C, Jimenez Y, Moreno JA, Delgado-Lista J, Egido J and Perez-Jimenez F (2006) The chronic intake of a Mediterranean diet enriched in virgin olive oil, decreases nuclear transcription factor kappaB activation in peripheral blood mononuclear cells from healthy men. Atherosclerosis in press
Perez-Moreno M, Davis MA, Wong E, Pasolli HA, Reynolds AG and Fuchs (2006) p120-catenin mediates inflammatory responses in the skin. Cell 124 631-644
Pérez-Otaño I, McMillian MK, Chen J, Bing G, Hong JS and Pennypacker KR (1996) Induction of NF-kB-like transcription factors in brain areas susceptible to kainate toxicity. Glia 16 306-315
Perez-Rodriguez R, Fuentes MP, Olivan AM, Martinez-Palacian A, Roncero C, Gonzalez MP and Oset-Gasque MJ (2007) Mechanisms of nitric oxide-induced apoptosis in bovine chromaffin cells: Role of mitochondria and apoptotic proteins. Journal ofNeuroscience Research in press
Perez-Sala D, Cernuda-Morollon E, Pineda-Molina E and Canada FJ (2002) Contribution of covalent protein modification to the antiinflammatory effects of cyclopentenone prostaglandins. Annals of the New York Academy of Sciences 973 533-536
Perfettini JL, Castedo M, Roumier T, Andreau K, Nardacci R, Piacentini M and Kroemer G (2005) Mechanisms of apoptosis induction by the HIV-1 envelope. Cell Death and Differentiation in press
Perfettini JL, Roumier T, Castedo M, Larochette N, Boya P, Raynal B, Lazar V, Ciccosanti F, Nardacci R, Penninger J, Piacentini M and Kroemer G (2004) NF-kB and p53 are the dominant apoptosis-inducing transcription factors elicited by the HIV-1 envelope. Journal of Experimental Medicine 199 629-640
Perfetto B, Donnarumma G, Criscuolo D, Paoletti I, Grimaldi E, Tufano MA and Baroni A (2003) Bacterial components induce cytokine and intercellular adhesion molecules-1 and activate transcription factors in dermal fibroblasts. Research in Microbiology 154 337-344
Perfetto B, Lamberti M, Giuliano MT, Canozo N, Cammarota M and Baroni A (2007) Analysis of the signal transduction pathway of nickel-induced matrix metalloproteinase-2 expression in the human keratinocytes in vitro: preliminary findings. Journal ofCutaneous Pathology 34 441-447
Perides G, Sharma A, Gopal A, Tao X, Dwyer K, Ligon B and Steer ML (2005) Secritin differentially sensitizes rat pancreatic acini to ethe effects of supramaximal stimulation with caerulein. American Journal of Physiology: Gastrointestinal and Liver Physiology 289 G686-695
Pereira RM, Calegari-Silva TC, Hernandez MO, Saliba AM, Redner P, Pessolani MC, Sarno EN, Sampaio EP and Lopes UG (2005) Mycobacterium leprae induces NF-kB-dependent transcription repression in human Schwann cells. Biochemical and Biophysical Research Commununications 335 20-26
Pergola C, Rossi A, Dugo P, Cuzzocrea S and Sautebin L (2006) Inhibition of nitric oxide biosynthesis by anthocyanin fraction of blackberry extract. Nitric Oxide 15 30-39
Perissi V, Aggarwal A, Glass CK, Rose DW and Rosenfeld MG (2004) A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors. Cell 116 511-526
Perissi V, Scafaoglio C, Zhang J, Ohgi KA, Rose DW, Glass CK and Rosenfeld MG (2008) TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints. Molecular Cell 29 755-766
Perkins ND (1997) Achieving transcriptional specificity with NF-kB. International Journal of Biochemistry and Cell Biology 29 1433-1448
Perkins ND (2000) The Rel/NF-kB family: friend and foe. Trends in Biochemical Sciences 25 434-440
Perkins ND (2003) Oncogenes, tumor suppressors and p52 NF-kB. Oncogene 22 7553-7556
Perkins ND (2004) NF-kB: tumor promoter or suppressor? Trends in Cell Biology 14 64-69
Perkins ND (2004) Regulation of NF-kB by atypical activators and tumour suppressors. Biochem Soc Trans 32 936-939
Perkins ND (2006) Post-translational modifications regulating the activity and function of the nuclear factor kB pathway.Oncogene 25 6717-6730
Perkins ND (2007) Integrating cell-signalling pathways with NF-kB and IKK function. Nature Reviews Molecular Cell Biology 8 49-62
Perkins ND, Agranoff AB, Pascal E and Nabel GJ (1994) An interaction between the putative DNA-binding domains of RelA(p65) and Sp1 mediates human immunodeficiency virus gene activation. Molecular and Cellular Biology 14 6570-6583
Perkins ND, Edwards NL, Duckett CS, Agranoff AB, Schmid RM and Nabel GJ (1993) A cooperative interaction between NF-kB and Sp1 is required for HIV-1 enhancer activation. EMBO Journal 12 3551-3558
Perkins ND, Felzien LK, Betts JC, Leung K, Beach DH and Nabel GJ (1997) Regulation of NF-kB by cyclin-dependent kinases associated with the p300 coactivator. Science 275 523-527
Perkins ND and Gilmore TD (2006) Good cop, bad cop: the different faces of NF-kB. Cell Death and Differentiation 13 759-772
Perkins ND, Schmid RM, Duckett CS, Leung K, Rice NR and Nabel GJ (1992) Distinct combinations of NF-kB subunits determine the specificity of transcriptional activation. Proceedings of the National Academy of Sciences USA 89 1529-1533
Permana PA, Menge C and Revaen PD (2006) Macrophage-secreted factors induce adipocyte inflammation and insulin resistance.Biochemical and Biophysical Research Communications in press
Pernerstorfer T, Stohlawetz P, Hollenstein U, Dzirlo L, Eichler HG, Kapiotis S, Jilma B and Speiser W (1999) Endotoxin-induced activation of the coagulation cascade in humans: effect of acetylsalicylic acid and acetaminophen. Arteriosclerosis, Thrombosis and Vascular Biology 19 2517-2523
Pero RW, Axelsson B, Siemann D, Chaplin D and Dougherty G (1999) Newly discovered anti-inflammatory properties of the benzamides and nicotinamides. Molecular and Cellular Biochemistry 193 119-125
Perona JS, Cabello-Moruno R and Ruiz-Gutierrez V (2006) The role of virgin olive oil components in the modulation of endothelial function. Journal of Nutritional Biochemistry 17 429-445
Perona R, and Sanchez-Perez I (2007) Signalling pathways involved in clinical responses to chemotherapy. Clinical and Translational Oncology 9 625-633
Perrella MA, Pellacani A, Wiesel P, Chin MT, Foster LC, Ibanez M, Hsieh CM, Reeves R, Yet SF and Lee ME (1999) High mobility group-I(Y) protein facilitates nuclear factor-kB binding and transactivation of the inducible nitric-oxide synthase promoter/enhancer. Journal of Biological Chemistry 274 9045-9052
Perrin-Cocon L, Agaugue S, Coutant F, Masurel A, Bezzine S, Lambeau G, Andre P and Lotteau V (2004) Secretory phospholipase A(2) induces dendritic cell maturation. European Journal of Immunology 34 2293-2302
Perrin-Schmitt F (1992) rel, NFKB, and the Brachyury T gene. Biochimica et Biophysica Acta 1171 129-131
Perroud TD, Kaiser JN, Sy JC, Lane TW, Branda CS, Singh AK and Patel KD (2008) Microfluidic-based cell sorting of Francisella tularensis infected macrophages using optical forces. Analytic Chemistry in press
Perry AK, Chow EK, Goodnough JB, Yeh WC and Cheng G (2004) Differential requirement for TANK-binding kinase-1 in type I interferon responses to Toll-like receptor activation and viral infection. Journal of Experimental Medicine 199 1651-1658
Perseghin G, Petersen K and Shulman GI (2003) Cellular mechanism of insulin resistance: potential links with inflammation. International Journal of Obesity and Related Metabolic Disorders 27 S6-S11
Persichini T, Cantoni O, Suzuki H and Colasanti M (2006) Cross-talk between constitutive and inducible NO synthase: an update. Antioxidant and Redox Signaling 8 949-954
Perscichini T, Percario Z, Mazzon E, Colasanti M, Cuzzocrea S and Musci G (2006) Copper activates the NF-kB pathway in vivo.Antioxidant and Redox Signaling 8 1897-1904
Persson E, Voznesensky OS, Huang YF and Lerner UH (2005) Increased expression of interleukin-6 by vasoactive intestinal peptide is associated with regulation of CREB, AP-1 and C/EBP, but not NF-kB, in mouse calvarial osteoblasts. Bone 37 513-529
Persson K, Dean-Mckinney T, Steers WD and Tuttle JB (2001) Activation of the transcription factors nuclear factor-kB and activator protein-1 in bladder smooth muscle exposed to outlet obstruction and mechanical stretching. Journal of Urology 165 633-639
Pessler F and Cron RQ (2004) Reciprocal regulation of the nuclear factor of activated T cells and HIV-1. Genes & Immunity 5 158-167
Petak I and Houghton JA (2001) Shared pathways: death receptors and cytotoxic drugs in cancer therapy. Pathol Oncol Res 7 95-106
Peter ME, Legembre P and Barnhart BC (2005) Does CD95 have tumor promoting activities? Biochimica et Biophysica Acta 1755 25-36
Peters JM, Hollingshead HE and Gonzalez FJ (2008) Role of peroxisome-proliferator-activated receptor beta/delta (PPARb/d) in gastrointestinal tract function and disease. Clinical Sciences (London) 115 107-127
Peters K, Chattopadhyay S adn Sen GC (2008) IRF-3 activation by Sendai virus infection is required for cellular apoptosis and avoidance of persistance. Journal of Virology in press
Peters KL, Smith HL, Stark GR and Sen GC (2002) IRF-3-dependent, NFkappa B- and JNK-independent activation of the 561 and IFN-beta genes in response to double-stranded RNA. Proceedings of the National Academy of Sciences USA 99 6322-6327
Peters RT and Maniatis T (2001) A new family of IKK-related kinases may function as IkB kinase kinases. Biochimica et Biophysica Acta 1471 M57-M62
Peters RT, Liao SM and Maniatis T (2000) IKKe is part of a novel PMA-inducible IkB kinase complex. Molecular Cell 5 513-522
Petersen CA, Krumholz KA and Burleigh BA (2005) Toll-like receptor 2 regulates interleukin-1beta-dependent cardiomyocyte hypertrophy triggered by Trypanosoma cruzi. Infection and Immunity 73 6974-6980
Petersen CA, Krumholz KA, Carmen J, Sinai AP and Burleigh BA (2006) Trypanosoma cruzi infection and nuclear factor kB activation prevent apoptosis in cardiac cells. Infection and Immunity 74 1580-1587
Petersen LG, Storling J, Heding P, Li S, Berezin V, Saldeen J, Billestrup N, Bock E and Mandrup-Poulsen T (2006) IL-1beta-induced pro-apoptotic signalling is facilitated by NCAM/FGF receptor signalling and inhibited by the C3d ligand in the INS-1E rat beta cell line.
Diabetologia in press
Petersen UM, Bjorkland G, Ip YT and Engstrom Y (1995) The dorsal-related immunity factor, Dif, is a sequence-specific trans-activator of Drosophila Cecropin gene expression. EMBO Journal 14 3146-3158
Peterson DA and Levine AS (1971) Avian reticuloendotheliosis virus (strain T). IV. Infectivity and transmissibility in day old cockerels. Avian Diseases 15 336-347
Peterson JR, Infanger DW, Braga VA, Zhang Y, SHarma RV, Engelhardt JF and Davisson RL (2008) Longitudinal non-invasive monitoring of transcription factor activation in cardiovascular regulatory nuclei using bioluminescence imaging. Physiological Genomics in press
Petit F, Flageul B, Gerbault O, Sarfati F, Revol M and Servant JM (2002) Dorsal and laterothoracic radiodermatitis after interventional cardiography. Plast Reconstr Surg 109 1655-1657
Petlickovski A, Laurenti L, Li X, Marietti S, Chiusolo P, Sica S, Leone G and Efremov DG (2005) Sustained signaling through the B-cell receptor induces Mcl-1 and promotes survival of chronic lymphocytic leukemia B-cells. Blood 105 4820-4827
Petrenko O, Ischenko I and Enrietto PJ (1995) Isolation of a cDNA encoding a novel chicken chemokine homologous to mammalian macrophage inflammatory protein-1b. Gene 160 305-306
Petrenko O, Ischenko I and Enrietto PJ (1997) Characterization of changes in gene expression associated with malignant transformation by the NF-kB family member, v-Rel. Oncogene 15 1671-1680
Petrilli V, Herceg Z, Hassa PO, Patel NS, Di Paola R, Cortes U, Dugo L, Filipe HM, Thiemermann C, Hottiger MO, Cuzzocrea S and Wang ZQ (2004) Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice. Journal of Clinical Investigation 114 1072-1081
Petro JB, Castro I, Lowe J and Khan WN (2002) Bruton’s tyrosine kinase targets NF-kB to the bcl-x promoter via a mechanism involving phospholipase C-gamma2 following B cell antigen receptor engagement. FEBS Letters 532 57-60
Petro JB and Khan WN (2001) Phospholipase C-g2 couples Bruton’s tyrosine kinase is to the NF-kB signaling pathway in B lymphocytes. Journal of Biological Chemistry 276 1715-1719
Petro JB, Rahman SMJ, Ballard DW and Khan WN (2000) Bruton’s tyrosine kinase is required for activation of IkB kinase and nuclear factor kB in response to B cell receptor engagement. Journal of Experimental Medicine 191 1745-1753
Petro TM (2003) Modulation of IL-12 p35 and p40 promoter activity by smokeless tobacco extract is associated with an effect upon activation of NF-kB but not IRF transcription factors. International Immunopharmacology 3 735-745
Petrof EO, Kojima K, Ropeleski MJ, Musch MW, Tao Y, De Simone C and Chang EB (2004) Probiotics inhibit nuclear factor-kB and induce heat shock proteins in colonic epithelial cells through proteasome inhibition. Gastroenterology 127 1474-1487
Petropoulos L and Hiscott J (1998) Association between HTLV-1 Tax and IkBa is dependent on the IkBa phosphorylation state. Virology 252 189-199
Petropoulos L, Lin R and Hiscott J (1996) Human T cell leukemia virus type 1 Tax protein increases NF-kB dimer formation and antagonizes the inhibitory activity of the IkBa regulatory protein. Virology 225 52-64
Petrova RD, Mahajna J, Reznick AZ, Wasser SP, Denchev CM and Nevo E (2006) Fungal substances as modulators of NF-kB activation pathway. Molecular Biology Reports in press
Petrova RD, Mahajna J, Wasser SP, Ruimi N, Denchev CM, Sussan S, Nevo E and Reznick AZ (2008) Marasmius oreades substances block NF-kB activity through interference with IKK activation pathway. Molecular Biology Reports in press
Petrova RD, Reznick AZ, Wasser SP, Denchev CM, Nevo E and Mahajna J (2008) Fungal metabolites modulating NF-kB activity: an approach to cancer therapy and chemoprevention. Oncoology Reports 19 299-308
Petrovic SD, Dobric S, Bokonjic D, Niketic M, Garcia-Pineres A and Merfort I (2003) Evaluation of Tanacetum larvatum for an anti-inflammatory activity and for the protection against indomethacin-induced ulcerogenesis in rats. Journal of Ethnopharmacology 87 109-113
Pettersson AT, Laurencikiene J,Nordstrom EA, Stenson BM, van harmelen V, Murphy C, Dahlman I and Ryden M (2008) Characterization of the human CIDEA promoter in fat cells. International Journal of Obesity (London) in press
Pevsner-Fisher M, Morad V, Cohen-Sfady M, Rousso-Norri L, Zanin-Zhorov A, Cohen IR and Zipori D (2007) Toll-like receptors and their ligands control mesenchymal stem cell functions. Blood 109 1422-1432
Pfahl M and Piedrafita FJ (2003) Retinoid targets for apoptosis induction. Oncogene 22 9058-9062
Pfeffer U, Ferrari N, Dell’eva R, Indraccolo S, Morini M, Noonan DM and Albini A (2005) Molecular mechanisms of action of angiopreventive anti-oxidants on endothelial cells: microarray gene expression analyses. Mutation Research 59 198-211
Pfeifer D, Pantic M, Skatulla I, Rawluk J, Kreutz C, Martens UM, Fisch P, Timmer J and Veelken H (2007) Genome-wide analysis of DNA copy number changes and LOH in CLL using high-density SNP arrays. Blood 109 1202-1210
Pfeifhofer C, Gruber T, Letschka T, Thuille N, Lutz-Nicoladoni C, Hermann_Kleiter N, Braun U, Leitges M and Baier G (2006) Defective IgG2a/2b class switching in PKCalpha-/- mice.
Journal of Immunology 176 6004-6011
Pfeifhofer C, Kofler K, Gruber T, Tabrizi NG, Lutz C, Maly K, Leitges M and Baier G (2003) Protein kinase C {theta} affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells. Journal of Experimental Medicine 197 1525-1535
Pham LV, Tamayo AT, Yoshimura LC, Lo P and Ford RJ (2003) Inhibition of constitutive NF-kB activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis. Journal of Immunology 171 88-95
Pfau JC, Schneider JC, Archer AJ, Sentissi J, Leyva FJ and Cramton J (2003) Environmental oxygen tension affects phenotype in cultured bone marrow derived macrophages. American Journal of Physiology: Lung Cell and Molecular Physiology 286 L354-L362
Pfeffer LM, Kim JG, Pfeffer SR, Carrigan DJ, Baker DP, Wei LW and Homayouni R (2004) The role of NF-kB in the antiviral action of interferon and interferon-regulated gene expression. Journal of Biological Chemistry 279 31304-31311
Pfluger PT, Herranz D, Velasco-Miguel S, Serrano M and Tschop MH (2008) Sirt1 protects against high-fat diet-induced metabolic damage. Proceedings of the National Academy of Sciences USA 105 9793-9798
Pfuhl T, Durr M, Spurk A, Schwalbert B, Nord R, Mysliwietz J, Kremmer E and Grasser FA (2005) Biochemical characterisation of the proteins encoded by the DiGeorge critical region 6 (DGCR6) genes. Human Genetics 117 70-80
Pham CG, Bubici C, Zazzeroni F, Knabb JR, Papa S, Kuntzen C and Franzoso G (2007) Upregulation of Twist-1 by NF-kB blocks cytotoxicity induced by chemotherapeutic drugs. Molecular and Cellular Biology in press
Pham CG, Bubici C, Zazzeroni F, Papa S, Jones J, Alvarez K, Jayawardena S, De Smaele E, Cong R, Beaumont C, Torti FM, Torti SV and Franzoso G (2004) Ferritin heavy chain upregulation by NF-kB inhibits TNFalpha-induced apoptosis by suppressing reactive oxygen species. Cell 119 529-542
Phan HH, Cho K, Nelson HA, Shin S, Jeong J and Greenhalgh DG (2004) Downregulation of NF-kB activity associated with alteration in proliferative response in the spleen after burn injury. Shock 23 73-79
Phan HH, Cho K, Sainz-Lyon KS, Shin S and Greenhalgh DG (2006) CD14-dependent modulation of NF-kaB alternative splicing in the lung after burn injury. Gene in press
Phares W, Franza Jr BR and Herr W (1992) The kB enhancer motifs in human immunodeficiency virus type 1 and simian virus 40 recognize different binding activities in human Jurkat and H9 T cells: eviidence for NF-kB-independent activation of the kB motif. Journal of Virology 66 7490-7498
Phelan PE, Mellon MT and Kim CH (2005) Functional characterization of full-length TLR3, IRAK-4, and TRAF6 in zebrafish (Danio rerio). Molecular Immunology 42 1057-1071
Phelps CB and Ghosh G (2004) Discreet mutations from c-Rel to v-Rel alter kB DNA recognition, IkBa binding, and dimerization: implications for v-Rel oncogenicity. Oncogene 23 1229-1238
Phelps CB, Sengchanthalangsy LL, Malek S and Ghosh G (2000) Mechanism of kB DNA binding by Rel/NF-kB dimers. Journal of Biological Chemistry 275 24392-24399
Philbin VJ and Levy O (2007) Immunostimulatory activity of Toll-like receptor 8 agonists towards human leucocytes: basic mechanisms and translational opportunities. Biochemical Society Transactions 35 1485-1491
Philip M, Rowley DA and Schreiber H (2004) Inflammation as a tumor promoter in cancer induction. Seminars in Cancer Biology 14 433-439
Philip S, Bulbule A and Kundu GC (2001) Osteopontin stimulates tumor growth and activation of promatrix metalloproteinase-2 through nuclear factor-kB-mediated induction of membrane type 1 matrix metalloproteinase in murine melanoma cells. Journal of Biological Chemistry 276 44926-44935
Philip S, Bulbule A and Kundu GC (2004) Matrix metalloproteinase-2: Mechanism and regulation of NF-kB-mediated activation and its role in cell motility and ECM-invasion. Glycoconj J 21 429-441
Philip S and Kundu GC (2003) Osteopontin induces nuclear factor-kB-mediated promatrix metalloproteinase-2 activation through IkBa/IKK signaling pathways and curcumin (Diferulolylmethane) down regulates these pathways. Journal of Biological Chemistry 278 14487-14497
Philippe D, Chakass D, Thuru X, Zerbib P, Tsicopoulos A, Beboes K, Bulois P, Breisse M, Vorng H, Gay J, Colombel JF, Desreumaux P and Chamaillard M (2005) mu-opioid receptor expression is increased in inflammatory bowel diseases: implications for homeostatic intestinal inflammation. Gut in press
Phillips RJ and Ghosh S (1997) Regulation of IkBb in WEHI mature B cells. Molecular and Cellular Biology 17 4390-4396
Phillips RJ, Gustafson S and Ghosh S (1996) Identification of a novel NF-kB p50-related protein in B lymphocytes. Molecular and Cellular Biology 16 7089-7097
Phillips T and Leeuwenburgh C (2005) Muscle fiber-specific apoptosis and TNF-alpha signaling in sarcopenia are attenuated by life-long calorie restriction. FASEB Journal 19 668-670
Philpott DJ and Viala J (2004) Towards an understanding of the role of NOD2/CARD15 in the pathogenesis of Crohn’s disease. Best Pract Res Clin Gastroenterol 18 555-568
Philpott NJ, Nociari M, Elkon KB and Falck-Pedersen E (2004) Adenovirus-induced maturation of dendritic cells through a PI3 kinase-mediated TNF-{alpha} induction pathway. Proceedings of the National Academy of Sciences USA 1-1 6200-6205
Piatelli MJ, Wardle C, Blois J, Doughty C, Schram BR, Rothstein TL and Chiles TC (2004) Phosphatidylinositol 3-kinase-dependent mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 and NF-kB signaling pathways are required for B cell antigen receptor-mediated cyclin d2 induction in mature B cells. Journal of Immunology 172 2753-2762
Piao HZ, Jin SA, Chun HS, Lee JC and Kim WK (2004) Neuroprotective effect of wogonin: potential roles of inflammatory cytokines. Arch Pharm Res 27 930-936
Piao W, Song C, Chen H, Wahl LM, Fitzgerald KA, O’Neill LA and Medvedev AE (2007) Tyrosine phosphorylation of MyD88 adapter-like (Mal) is critical for signal transduction and blocked in endotoxin tolerance. Journal of Biological Chemistry in press
Piao YJ, Seo YH, Hong F, Kim JH, Kim YJ, Kang MH, Kim BS, Jo SA, Jo I, Jue DM, Kang I, Ha J and Kim SS (2005) Nox 2 stimulates muscle differentiation via NF-kB/iNOS pathway. Free Radic Biol Med 38 989-1001
Piazza FA, Ruzzene M, Gurrieri C, Montini B, Bonanni L, Chioetto G, Di Maira G, Barbon F, Cabrelle A, Zambello F, Adami F, Trentin L, Pinna LA and Semenzato G (2006) Multiple myeloma cell survival relies on high activity of protein kinase CK2.Blood in press
Picado C, Bioque G, Roca-Ferrer J, Pujols L, Mullol J, Benitez P and Bulbena O (2003) Nuclear factor-kB activity is down-regulated in nasal polyps from aspirin-sensitive asthmatics. Allergy 58 122-126
Picard C and Casonova JL (2004) Inherited disorders of cytokines. Current Opinion in Pediatrics 16 648-658
Picard C, Puel A, Bonnet M, Ku CL, Bustamante J, Yang K, Soudais C, Dupuis S, Feinberg J, Fieschi C, Elbim C, Hitchcock R, Lammas D, Davies G, Al-Ghonaium A, Al-Rayes H, Al-Jumaah S, Al Hajjar S, Al-Mohsen IZ, Frayha HH, Rucker R, Hawn TR, Aderem A, Tufenkeji H, Haraguchi S, Day NK, Good RA, Gougerot-Pocidalo MA, Ozinsky A and Casanova JL (2003) Pyogenic bacterial infections in humans with IRAK-4 deficiency. Science 299 2076-2079
Picard C, Puel A, Bustamante J, Ku CL and Casanova JL (2003) Primary immunodeficiencies associated with pneumococcal disease. Current Opinion in Allergy and Clinical Immunology 3 451-459
Piccaluga PP, Agostinelli C, Califano A, Carbone A, Fantoni L, Ferrari S, Gazzola A, Gloghini A, Righi S, Rossi M, Tagliafico E, Zinzani PL, Zupo S, Baccarani M and Pileri SA (2007) Gene expression analysis of angioimmunoblastic lymphoma indicates derivation from T follicular helper cells and vascular endothelial growth factor deregulation. Cancer Research 67 10703-10710
Piccioli P, Porcile C, Stanzione S, Bisaglia M, Bajetto A, Bonavia R, Florio T and Schettini G (2001) Inhibition of nuclear factor-kB activation induces apoptosis in cerebellar granule cells. Journal of Neuroscience Research 66 1064-1073
Piccolella E, Spadaro F, Ramoni C, Marinari B, Costanzo A, Levrero M, Thomson L, Abraham RT and Tuosto L (2003) Vav-1 and the IKKalpha subunit of IkB kinase functionally associate to induce NF-kB activation in response to CD28 engagement. Journal of Immunology 170 2895-2903
Pichavant M, Delneste Y, Jeannin P, Fourneau C, Brichet A and Tonnel AB, Gosset P (2003) Outer membrane protein A from Klebsiella pneumoniae activates bronchial epithelial cells: implication in neutrophil recruitment. Journal of Immunology 171 6697-6705
Pichler K, Kattan T, Gentzsch J, Kress AK, Taylor GP, Bangham CR and Grassmann R (2008) Strong induction of 4-1BB, a growth and survival promoting costimulatory receptor, in HTLV-1-infected cultured and patients’ T-cells by the viral Tax oncoprotein. Blood in press
Pick R, Badura S, Bosser S and Zornig M (2006) Upon intracellular processing, the C-terminal death domain-containing fragment of the p53-inducible PIDD/LRDD protein translocates to the nucleoli and interacts with nucleolin. Biochemical and BiophysicalResearch Communications in press
Pickell L, Tran P, Leclerc D, Hiscott J and Rozen R (2005) Regulatory studies of murine methylenetetrahydrofolate reductase reveal two major promoters and NF-kB sensitivity. Biochimica et Biophysica Acta 1731 104-114
Pickering BM, de Mel S, Lee M, Howell M, Habens F, Dallman CL, Neville LA, POtter KN, Mann J, Mann DA, Johnson PW, Stevenson FK and Packham G (2006) Pharmacological inhibitors of NF-kB accelerate apoptosis in chronic lymphocytic leukaemia cells.Oncogene in press
Pieper CM, Roza AM, Henderson Jr JD, Zhu YR and Lai CS (2004) Spatial distribution and temporal onset of NF-kB activation and inducible nitric oxide synthase within pancreatic islets in the pre-diabetic stage of genetic, diabetic-prone BB rats: attenuation by drug intervention decreases inflammatory cell infiltration and incidence of diabetes. Inflammation Research 53 22-30
Pieper GM, Nilakantan V, Hilton G, Halligan NL, Felix CC, Kampalath B, Khanna AK, Roza AM, Johnson CP and Adams MB (2003) Mechanisms of the protective action of diethyldithiocarbamate-iron complex on acute cardiac allograft rejection. American Journal of Physiology: Heart and Circulatory Physiology 284 H1542-H1551
Pieper GM, Nilakantan V, Hilton G, Zhou X, Khanna AK, Halligan NL, Felix CC, Kampalath B, Griffith OW, Hayward MA, Roza AM and Adams MB (2004) Variable efficacy of N6-(1-iminoethyl)-L-lysine in acute cardiac transplant rejection. American Journal of Physiology: Heart and Circulatory Physiology 286 H525-H534
Pieper GM, Nilakantan V, Zhou X, Khanna AK, Johnson CP, Roza AM, Adams MB, Hilton G and Felix CC (2004) Treatment with {alpha}-phenyl-N-tert-butylnitrone, a free radical trapping agent, abrogates inflammatory cytokine gene expression during alloimmune activation in rat cardiac allografts. Journal of Pharmacology and Experimental Therapeutics 312 774-779
Pieper GM, Olds CL, Bub JD and Lindholm PF (2002) Transfection of human endothelial cells with HIV-1 tat gene activates NF-kB and enhances monocyte adhesion. American Journal of Physiology: Heart and Circulatory Physiology 283 H2315-H2321
Pieper GM and Riaz-ul-Haq (1997) Activation of nuclear factor-kappaB in cultured endothelial cells by increased glucose concentration: prevention by calphostin C. J Cardiovasc Pharmacol 30 528-532
Pieper GM, Siebeneich W, Olds CL, Felix CC and Soldato PD (2002) Vascular protective actions of a nitric oxide aspirin analog in both in vitro and in vivo models of diabetes mellitus. Free Radic Biol Med 32 1143-1156
Pieper GM, Siebeneich W, Olds CL and Lai CS (2003) Chronic or delayed treatment with an oral dithiocarbamate analog decreases glycation and protects diabetic arteries. European Journal of Pharmacology 472 127-134
Pierangeli SS, Vega-Ostertag M and Nigel Harris E (2004) Intracellular signaling triggered by antiphospholipid antibodies in platelets and endothelial cells: a pathway to targeted therapies. Thrombosis Research 114 467-476
Pierce JW, CA Jamieson, JL Ross and R Sen (1995) Activation of IL-2 receptor a-chain gene by individual members of the rel oncogene family in association with serum response factor. Journal of Immunology 155 1972-1980
Pierce JW, Read MA, Ding H, Luscinaskas FW and Collins T (1996) Salicylates inhibit IkB-a phosphorylation, endothelial-leukocyte adhesion molecule expression, and neutrophil transmigration. Journal of Immunology 156 3961-3969
Pierce JW, Schoenleber R, Jesmok G, Best J, Moore SA, Collins T and Gerritsen ME (1997) Novel inhibitors of cytokine-induced IkBa phosphorylation and endothelial cell adhesion molecule expression show anti-inflamatory effects in vivo. Journal of Biological Chemistry 272 21096-21103
Piercy J, Petrova S, Tchilian EZ and Beverley PC (2006) CD45 negatively regulates tumour necrosis factor and interleukin-6 production in dendritic cells. Immunology 118 250-256
Pierer M, Brentano F, Rethage J, Wagner U, Hantzschel H, Gay RE, Gay S and Kyburz D (2007) The TNF superfamily member LIGHT contributes to survival and activation of synovial fibroblasts in rheumatoid arthritis. Rheumatology (Oxford) in press
Pietila TE, Veckman V, Lehtonen A, Lin R, Hiscott J and Julkunen I (2007) Multiple NF-kB and IFN Regulatory Factor family transcription factors regulate CCL19 gene expression in human monocyte-derived dendritic cells. Journal of Immunology 178253-261
Piga R, Naito Y, Kokura S, Handa O and Yoshikawa T (2006) Short-term high glucose exposure induces monocyte-endothelial cells adhesion and transmigration by increasing VCAM-1 and MCP-1 expression in human aortic endothelial cells. Atherosclerosis in press
Pinlaor S, Tada-Oikawa S, Hiraku Y, Pinlaor P, Ma N, Sithithaworn P and Kawanishi S (2005) Opisthorchis viverrini antigen induces the expression of Toll-like receptor 2 in macrophage RAW cell line. International Journal of Parasitology 35 591-596
Prince LS, Dieperink HI, Okoh VO, Fierro-Perez GA and Lallone RL (2005) Toll-like receptor signaling inhibits structural development of the distal fetal mouse lung. Developmental Dynamics 233 553-561
Pierce MA, Chapman HD, Post CM, Svetlanov A, Efrat S, Horwitz M and Serreze DV (2003) Adenovirus Early region 3 antiapoptotic 10.4K, 14.5K, and 14.7K genes decrease the incidence of autoimmune diabetes in NOD mice. Diabetes 52 1119-1127
Pietrella D, Corbucci C, Perito S, Bistoni G and Vecchiarelli A (2005) Mannoproteins from Cryptococcus neoformans promote dendritic cell maturation and activation. Infection and Immunity 73 820-827
Pietro RD and Zauli G (2004) Emerging non-apoptotic functions of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)/Apo2L. Journal of Cell Physiology 201 331-340
Piffat KA, Hrdlickova R, Nehyba J, Ikeda T, Liss A, Huang S, Sif S, Gilmore TD and Bose HR Jr (2001) The chicken RelB transcription factor has transactivation sequences and a tissue-specific expression pattern that are distinct from mammalian RelB. Molecular and Cellular Biology Research Communications 4 266-275
Pignatelli M, Sanchez-Rodriguez J, Santos A and Perez-Castillo A (2004) 15-deoxy-{Delta}-12,14-prostaglandin J2 induces programmed cell death of breast cancer cells by a pleiotropic mechanism. Carcinogenesis 26 81-92
Pikarsky E and Ben-Neriah Y (2006) NF-kB inhibition: A double-edged sword in cancer? European Journal of Cancer in press
Pikarsky E, Porat RM, Stein I, Abramovitch R, Amit S, Kasem S, Gutkovich-Pyest E, Urieli-Shoval S, Galun E and Ben-Neriah Y (2004) NF-kB functions as a tumour promoter in inflammation-associated cancer. Nature 431 461-466
Pileri SA, Zinzani PL, Gaidano G, Falini B, Gaulard P, Zucca E, Sabattini E, Ascani S, Rossi M and Vavalli F (2003) Pathobiology of primary mediastinal B-cell lymphoma. Leukemia and Lymphoma 44 S21-S26
Pilette C, Ouadrhiri Y, Dimanche F, Vaerman JP and Sibille Y (2003) Secretory component is cleaved by neutrophil serine proteinases but its epithelial production is increased by neutrophils through NF-kB- and p38 mitogen-activated protein kinase-dependent mechanisms. American Journal of Respiratory Cell and Molecular Biology 28 485-498
Pilichou A, Papassoutiriou I, Michalakakou K, Fessatou S, Fandridis E, Papachristou G and Terpos E (2008) High levels of synovial fluid osteoprotegerin (OPG) and increased serum ratio of receptor activator of nuclear factor-kB ligand (RANKL) to OPG correlate with disease severity in patients with primary knee osteoarthritis. Clinical Biochemistry in press
Pillinger MH, Dinsell V, Apsel B, Tolani SN, Marjanovic N, Chan ES, Gomez P, Clancy R, Chang LF and Abramson SB (2004) Regulation of metalloproteinases and NF-{kappa}B activation in rabbit synovial fibroblasts via E prostaglandins and Erk: contrasting effects of nabumetone and 6MNA. British Journal of Pharmacology 142 973-982
Pincheira R, Castro AF, Ozes ON, Idumalla PS and Donner DB (2008) Type 1 TNF receptor Forms a complex with and uses Jak2 and c-Src to selectively engage signaling pathways that regulate transcription factor activity. Journal of Immunology 181 1288-1298
Pindolia KR, Noth CJ, Xu YX, Janakiraman N, Chapman RA and Gautam SC (1996) IL-4 upregulates IL-l-induced chemokine gene expression in bone marrow stromal cells by enhancing NF-kB activation. Hematopathology and Molecular Hematology 10 171-185
Pineda B, Laporta P, Cano A and Garcia-Perez MA (2008) The Asn19Lys substitution in the osteoclast inhibitory lectin (OCIL) gene is associated with a reduction of bone mineral density in postmenopausal women. Califerous Tissue International in press
Pineda-Molina E, Klatt P, Vazquez J, Marina A, Garcia de Lacoba M, Perez-Sala D and Lamas S (2001) Glutathionylation of the p50 subunit of NF-kB: a mechanism for redox-induced inhibition of DNA binding. Biochemistry 40 14134-14142
Pineda-Molina E and Lamas S (2001) Nitric oxide as a regulator of gene expression: Studies with the transcription factor proteins cJun and p50. Biofactors 15 113-115
Ping B, He X, Xia W, Lee DF, Wei Y, Yu D, Mills G, Shi D and Hung MC (2006) Cytoplasmic expression of p32 CIP1/WAF1 is correlated with IKKb overexpression in human breast cancers. International Journal of Oncology 29 1103-1110
Ping C, Lin Z, Jiming D, Jin Z, Ying L, Shigang D, Hongtao Y, Yongwei H and Jiahong D (2006) The phosphoinositide 3-kinase/Akt-signal pathway mediates proliferation and secretory function of hepatic sinusoidal endothelial cells in rats after partial hepatectomy. Biochemical and Biophysical Research Communications 342 887-893
Pingle SC, Jajoo S, Mukherjea D, Sniderhan LF, Jhaveri KA, Marcuzzi A, Rybak LP, Maggirward SB and Ramkumar V (2007) Activation of the adenosine A1 receptor inhibits HIV-1 Tat-induced Apoptosis by reducing nuclear factor-kB activation and inducible nitric oxide synthase. Molecular Pharmacology in press
Pingle SC, Mishra S, Marcuzzi A, Bhat SG, Sekino Y, Rybak LP and Ramkumar V (2004) Osmotic diuretics induce adenosine A1 receptor expression and protect renal proximal tubular epithelial cells against cisplatin-mediated apoptosis. Journal of Biological Chemistry 279 43157-43167
Pingle SC, Sanchez JF, Hallam DM, Williamson AL, Maggirwar SB, Ramkumar V (2003) Hypertonicity inhibits lipopolysaccharide-induced nitric oxide synthase expression in smooth muscle cells by inhibiting nuclear factor kB. Molecular Pharmacology 63 1238-1247
Pinhal-Enfield G, Ramanathan M, Hasko G, Vogel SN, Salzman AL, Boons GJ and Leibovich SJ (2003) An angiogenic switch in macrophages involving synergy between Toll-like receptors 2, 4, 7, and 9 and adenosine A(2A) receptors. American Journal of Pathology 163 711-721
Pinkenburg O, Platz J, Beisswenger C, Vogelmeier C and Bals R (2004) Inhibition of NF-kB mediated inflammation by siRNA expressed by recombinant adeno-associated virus. Journal of Virological Methods 120 119-122
Pinkoski MJ, Droin NM and Green DR (2002) TNFa upregulates non-lymphoid Fas-ligand following superantigen-induced peripheral lymphocyte activation. Journal of Biological Chemistry 277 42380-42385
Pinlaor S, Hiraku Y, Yongvanit P, Tada-Oikawa S, Ma N, Pinlaor P, Sithithaworn P, Sripa B, Murata M, Oikawa S and Kwanishi S (2006) iNOS-dependent DNA damage via NF-kB expression in hamsters infected with Opisthorchis viverrini and its suppression by the antihelminthic drug praziquantel. International Journal of Cancer in press
Pinlaor S, Prakobwong S, Hiraku Y, Kaewsamut B, Dechakhamphu S, Boonmars T, Sithithaworn P, Pinlaor P, Ma N, Yongvanit P and Kwaanishi S (2008) Oxidative and nitrative stress in Opisthorchis viverrini-infected hamsters: an indirect effect after praziquantel treatment. American Journal of Tropical Medicine and Hygiene 78 564-573
Pinna GF, Fiorucci M, Reimund JM, Taquet N, Arondel Y and Muller CD (2004) Celastrol inhibits pro-inflammatory cytokine secretion in Crohn’s disease biopsies. Biochemical and Biophysical Research Communications 322 778-786
Pinsky MR (2004) Pathophysiology of sepsis and multiple organ failure: pro- versus anti-inflammatory aspects. Contrib Nephrol 144 31-43
Pino MS, Nawrocki ST, Cognetti F, Abruzzese JL, Xiong HQ and McConkey DJ (2005) Prostaglandin E(2) drives cyclooxygenase-2 expression via cyclic AMP Response element activation in human pancreatic cancer cells. Cancer Biology and Therapy in press
Pinteaux E, Parker LC, Rothwell NJ and Luheshi GN (2002) Expression of interleukin-1 receptors and their role in interleukin-1 actions in murine microglial cells. Journal of Neurochemistry 83 754-763
Piotrowska A, Izykowska I, Podhorska-Okolow M, Zabel M and Dziegiel P (2008) The structure of NF- kappaB family proteins and their role in apoptosis [Article in Polish]. Postepy Hig Med Dosw 62 64-74
Piotrowska MJ, Widera D, Kaltschmidt B, An der Heiden U and Kaltschmidt C (2006) Mathematical model for NF-kB-driven proliferation of adult neural stem cells. Cell Proliferation 39 441-455
Piraino G, Cook JA, O’connor M, Hake PW, Burroughs TJ, Teti D and Zingarelli B (2006) Synergistic effect of peroxisome proliferator activated receptor-gamma and liver X receptor-alpha in the regulation of inflammation in macrophages. Shock 26 146-153
Piret B, Schoonbroodt S and Piette J (1999) The ATM protein is required for sustained activation of NF-kB following DNA damage. Oncogene 18 2261-2271
Pisarchik A and Slominski A (2004) Molecular and functional characterization of novel CRFR1 isoforms from the skin. European Journal of Biochemistry 271 2821-2830
Pise-Masison CA and Brady JN (2005) Setting the stage for transformation: HTLV-1 Tax inhibition of p53 function. Frontiers in Bioscience 10 919-930
Pise-Masison CA, Mahieux R, Jiang H, Ashcroft M, Radanovich M, Duvall J, Guillerm C and Brady JN (2000) Inactivation of p53 by human T-cell lymphomatropic virus type 1 Tax requires activation of the NF-kB pathway and is dependent on p53 phosphorylation. Molecular and Cellular Biology 20 3377-3386
Pitt B (2004) Effect of aldosterone blockade in patients with systolic left ventricular dysfunction: implications of the RALES and EPHESUS studies. Molecular and Cellular Endocrinology 217 53-58
Pittet JF, Lee H, Pespeni M, O’mahony A, Roux J, Welch WJ (2005) Stress-induced inhibition of the NF-kB signaling pathway results from the insolubilization of the IkB kinase complex following its dissociation from heat shock protein 90. Journal of Immunology 174 384-394
Pittock ST, Norby SM, Grande JP, Croatt AJ, Bren GD, Badley AD, Caplice N< Griffin MD and Nath KA (2005) MCP-1 is up-regulated in unstressed and stressed HO-1 knockout mice: Pathophysiologic correlates. Kidney International 68 611-622
Pitzalis C, Pipitone N and Perretti M (2002) Regulation of leukocyte-endothelial interactions by glucocorticoids. Annals of the New York Academy of Sciences 966 108-118
Piva R, Belardo G and Santoro MG (2006) NF-kB: a stress-regulated switch for cell survival.
Antioxid Redox Signal 8 478-486
Piva R and Gambari R (2003) Transcription factor decoy (TFD) in breast cancer research and treatment. Technol Cancer Res Treat 1 405-416
Piva R, Gianferretti P, Ciucci A, Taulli R, Belardo G and Santoro MG (2005) 15-Deoxy-{Delta}12,14-prostaglandin J2 induces apoptosis in human malignant B-cells: an effect associated with inhibition of NF-kB activity and down-regulation of anti-apoptotic proteins. Blood 105 1750-1758
Piva R, Penolazzi L, Zennaro M, Bianchini E, Magri E, Borgatti M, Lampronti I, Lambertini E, Tavanti E and Gambari R (2006) Induction of apoptosis of osteoclasts by targeting transcription factors with decoy molecules. Annals of the New York Academy of Sciences 1091 509-516
Piva R, Ruggeri B, Williams M, Costa G, Tamagno I, Ferrero C, Giai V, Coscia M, Peola S, Massaia M, Pezzoni G, Allievi C, Pescalli N, Cassin M, di Giovine S, Nicoli P, de Feudis P, Strepponi I, Roato I, Ferracini R, Bussolati B, Camussi G, Jones-Bolin S, Hunter K, Zhao H, Neri A, Palumbo A, Berkers C, Ovaa H, Bernareggi A and Inghirami G (2007) CEP-18770: a novel orally-active proteasome inhibitor with a tumor-selective pharmacological profile competitive with bortezomib. Blood in press
Pivarcsi A, Bodai L, Rethi B, Kenderessy-Szabo A, Koreck A, Szell M, Beer Z, Bata-Csorgoo Z, Magocsi M, Rajnavolgyi E, Dobozy A and Kemeny L (2003) Expression and function of Toll-like receptors 2 and 4 in human keratinocytes. International Immunology 15 721-730
Pivarcsi A, Kemeny L and Dobozy A (2004) Innate immune functions of the keratinocytes. Acta Microbiol Immunol Hung 51 303-310
Pivarcsi A, Nagy I, Koreck A, Kis K, Kenderessy-Szabo A, Szell M, Dobozy A and Kemeny L (2005) Microbial compounds induce the expression of pro-inflammatory cytokines, chemokines and human beta-defensin-2 in vaginal epithelial cells. Microbes and Infection 7 1117-1127
Pizzi M, Goffi F, Boroni F, Benarese M, Perkins SE, Liou HC and Spano P (2002) Opposing roles for NF-kB/Rel factors p65 and c-Rel in the modulation of neuron survival elicited by glutamate and interleukin-1beta. Journal of Biological Chemistry 277 20717-20723
Pizzi M, Sarnico I, Boroni F, Benarese M, Steimberg N, Mazzoleni G, Dietz GP, Bahr M, Liou HC and Spano PF (2005) NF-kB factor c-Rel mediates neuroprotection elicited by mGlu5 receptor agonists against amyloid beta-peptide toxicity. Cell Death and Differentiation 12 761-772
Pizzi M, Sarnico I, Boroni F, Benarese M and Spano PF (2005) Inhibition of IkBa phosphorylation prevents glutamate-induced NF-kB activation and neuronal cell death. Acta Neurochir 93 59-63
Pizzi M and Spano P (2006) Distinct roles of diverse nuclear factor kB complexes in neuropathological mechanisms. European Journal of Pharmacology 545 22-28
Place RF, Haspeslagh D and Giardina C (2003) Induced stabilization of IkBa can facilitate its re-synthesis and prevent sequential degradation. Journal of Cell Physiology 195 470-478
Place RF, Noonan EJ and Giardina C (2005) HDAC inhibition prevents NF-kB activation by suppressing proteasome activity: Down-regulation of proteasome subunit expression stabilizes IkBa. Biochemical Pharmacology 70 394-406
Pladzyk A, Reddy AB, Yadav UC, Tammali R, Ramana KV, Srivastava SK (2006) Inhibition of aldose reductase prevents lipopolysaccharide-induced inflammatory response in human lens epithelial cells.
Investigative Ophthalmology & Visual Science 47 5395-5403
Plaisance S, Vanden Berghe W, Boone E, Fiers W and Haegeman G (1997) Recombination signal sequence binding protein Jk is constitutively bound to the NF-kB site of the interleukin-6 promoter and acts as a negative regulatory factor. Molecular and Cellular Biology 17 3733-3743
Planavila A, Calvo RR and Vazquez-Carrera M (2006) Peroxisome proliferator-activated receptors and the control of fatty acid oxidation in cardiac hypertrophy. Mini Reviews in Medicinal Chemistry 6 357-363
Planavila A, Laguna JC and Vazquez-Carrera M (2005) Nuclear factor-kB activation leads to down-regulation of fatty acid oxidation during cardiac hypertrophy. Journal of Biological Chemistry 280 17464-17471
Planavila A, Laguna JC and Vazquez-Carrera M (2005) Atorvastatin improves peroxisome proliferator-activated receptor signaling in cardiac hypertrophy by preventing nuclear factor-kappaB activation. Biochmica et Biophysica Acta 1687 76-83
Planvila A, Rodriguez-Calvo R, Fernandez de Arriba A, Sanchez RM, Laguna JC, Merlos M, Vazquez-Carrera M (2006) Inhibition of cardiac hypertrophy by triflusal (4-trifluoromethyl derivative of salicylate) and its active metabolite. Molecular Pharmacology in press
Planavila A, Rodriguez-Calvo R, Jove M, Michalik L, Wahli W, Laguna JC and Vazquez-Carrera M (2005) Peroxisome proliferator-activated receptor beta/delta activation inhibits hypertrophy in neonatal rat cardiomyocytes. Cardiovascular Research 65 832-841
Planavila A, Sanchez RM, Merlos M, Laguna JC and Vazquez-Carrera M (2005) Atorvastatin prevents peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) downregulation in lipopolysaccharide-stimulated H9c2 cells. Biochimica et Biophysica Acta 1736 120-127
Planz O (2006) Influenza virus and intracellular signalling pathways [Article in German].] Berl Munch Tierarztl Wochenschr119 101-111
Plaschke K, Feindt J, Djuric Z, Heiland S, Autschbach F, Lewicka S, Martin E, Barenheuer HJ, Nawroth PP and Biefhaus A (2006) Chronic corticosterone-induced deterioration in rat behaviour is not paralleled by changes in hippocampal NF-kB-activation.Stress 9 97-106
Plaskin D, Baeuerle PA and Eisenbach L (1993) KBF-1 (p50 NF-kB homodimer) acts as a repressor of H-2Kb gene expression in metastatic tumor cells. Journal of Experimental Medicine 177 1651-1662
Plat J and Mensink RP (2005) Food components and immune function. Current Opinions in Lipidology 16 31-37
Platten M, Eitel K, Wischhusen J, Dichgans J and Weller M (2003) Involvement of protein kinase Cdelta and extracellular signal-regulated kinase-2 in the suppression of microglial inducible nitric oxide synthase expression by N-[3,4-dimethoxycinnamoyl]-anthranilic acid (tranilast). Biochemical Pharmacology 66 1263-1270
Platz J, Beisswenger C, Dalpke A, Koczulla R, Pinkenburg O, Vogelmeier C and Bals R (2004) Microbial DNA induces a host defense reaction of human respiratory epithelial cells. Journal of Immunology 173 1219-1223
Platz J, Pinkenburg O, Beisswenger C, Puchner A, Damm T and Bals R (2005) Application of small interfering RNA (siRNA) for modulation of airway epithelial Gene expression. Oligonucleotides 15 132-138
Platzer B, Jorgl A, Taschner S, Hocher B and Strobl H (2004) RelB regulates human dendritic cell subset development by promoting monocyte intermediates. Blood in press
Plavec I, Sirenko O, Privat S, Wang Y, Dajee M, Melrose J, Nakao B, Hytopoulos E, Berg EL and Butcher EC (2004) Method for analyzing signaling networks in complex cellular systems. Proceedings of the National Academy of Sciences 101 1223-1228
Pleguezuelos O, Hagi-Pavli E, Crowther G and Kapas S (2004) Adrenomedullin signals through NF-kB in epithelial cells. FEBS Letters 577 249-254
Pleguezuelos O and Kapas S (2006) Differentiation of the HaCaT keratinocyte cell line: modulation by adrenomedullin. BritishJournal of Dermatology 154 602-608
Plesnila N, von Baumgarten L, Retiounskaia M, Engel D, Ardeshiri A, Zimmermann R, Hoffmann F, Landshamer S, Wagner E and Culmsee C (2007) Delayed neuronal death after brain trauma involves p53-dependent inhibition of NF-kB transcriptional activity. Cell Death and Differentiation in press
Plevy S and Mayer L (2003) Meeting summary: Signal transduction pathways in immune and inflammatory cells. November 30-December 3, 2000, Amelia Island, Florida, U.S.A. Inflammatory Bowel Disease 9 28-33
Plevy SE, Gemberling JHM, Hsu S, Dorner Aj and Smale ST (1997) Multiple control elements mediate activation of the murine and human interleukin 12 p40 promoters: evidence of functional synergy between C/EBP and Rel proteins. Molecular and Cellular Biology 17 4572-4588
Plummer SM, Holloway KA, Manson MM, Munks RJL, Kaptein A, Farrow S and Howells L (1999) Inhibition of cyclo-oxygenase 2 gene expression in colon cells by the chemopreventative agent curcumin involves inhibition of NF-kB activation via the NIK/IKK signalling complex. Oncogene 18 6013-1020
Pluvinet R, Olivar R, Krupinski J, Herrero-Fresneda I, Luque A, Torras J, Cruzado JM, Grinyó JM, Sumoy L, Aran JM (2008) CD40: an upstream master switch for endothelial cell activation uncovered by RNAi-coupled transcriptional profiling. Blood112 3624-3237
Pocock J, Gomez-Guerrero C, Harendza S, Ayoub M, Hernandez-Vargas P, Zahner G, Stahl RA and Thaiss F (2003) Differential activation of NF-kB, AP-1, and C/EBP in endotoxin-tolerant rats: mechanisms for in vivo regulation of glomerular RANTES/CCL5 expression. Journal of Immunology 170 6280-6291
Podgoreanu MV, Michelotti GA, Sato Y, SMith MP, LIn S, Morris RW, Grocott HP, Mathew JP and Schwinn DA (2005) Differential cardiac gene expression during cardiopulmonary bypass: Ischemia-independent upregulation of proinflammatory genes. Journal of Thoracic and Cardiovascular Surgery 130 330-339
Podhorecka M (2004) Apoptosis in pathogenesis of B-cell chronic lymphocytic leukemia [Article in Polish]. Postepy Hig Med Dosw 58 236-242
Podojil JR, Kin NW and Sanders VM (2004) CD86 and beta 2-adrenergic receptor signaling pathways, respectively, increase Oct-2 and OCA-B expression and binding to the 3′-IgH enhancer in B cells. Journal of Biological Chemistry 279 23394-23404
Podolin PL, Callahan JF, Bolognese BJ, Li YH, Carlson K, Davis TG, Mellor GW, Evans C and Roshak AK (2004) Attenuation of murine collagen-induced arthritis by a novel, potent and selective small molecule inhibitor of IkB kinase 2, TPCA-1, occurs via reduction of proinflammatory cytokines and antigen-induced T cell proliferation. Journal of Pharmacology and Experimental Therapeutics 312 373-381
Podtschaske M, Benary U, Zwinger S, Hofer T, Radbruch A and Baumgrass R (2007) Digital NFATc2 activation per cell transforms graded T cell receptor activation into an all-or-none IL-2 expression. PLoS ONE 2 e935
Poeckel D and Werz O (2006) Boswellic acids: biological actions and molecular targets.
Current Medicinal Chemistry 13 3359-3369
Poeppelmann B, Klimmek K, Strozyk E, Voss R, Schwarz T and Kulms D (2005) NFkappa B-dependent downregulation of TRAF proteins contributes to IL-1-mediated enhancement of UVB-induced apoptosis. Journal of Biological Chemistry 280 15635-15643
Pogson M, Holcombe M, Smallwood R and Qwarnstrom E (2008) Introducing spatial information into predictive NF-kB modelling–an agent-based approach. PLoS ONE 3 e2367
Pogson M, Smallwood R, Qwarnstrom E and Holcombe M (2006) Formal agent-based modelling of intracellular chemical interactions. Biosystems 85 37-45
Pohlmann S, Floss S, Ilyinskii PO, Stamminger T and Kirchhoff (1998) Sequences just upstream of the simian immunodeficiency virus core enhancer allow efficient replication in the absence of NF-kB and Sp1 binding elements. Journal of Virology 72 5589-5598
Poirier H, Shapiro JS, Kim RJ and Lazar MA (2006) Nutritional supplementation with trans-10, cis-12-conjugated linoleic acid induces inflammation of white adipose tissue. Diabetes 55 1634-1641
Poitevin S, Garnotel R, Antonicelli F, Gillery P and Nguyen P (2008) Type I collagen induces tissue factor expression and MMP-9 production in human primary monocytes through a redox-sensitive pathway. Journal of Thrombosis and Haemostosis in press
Pokharel YR, Lim SC, Kim SC, Heo TH, Choi HK and Kang KW (2008) Sopungyangjae-Tang inhibits development of dermatitis in Nc/Nga mice. Evidence Based Complementary Alternative Medicine 5 173-180
Pokharel YR, Liu QH, Oh JW, Woo ER and Kang KW (2007) 4-Hydroxykobusin inhibits the Induction of nitric oxide synthase by inhibiting NF-kB and AP-1 activation. Biological and Pharmaceutical Bulletin 30 1097-1101
Pokharel YR, Liu Zh, Kim YG, Woo ER and Kang KW (2006) 7,7′-dihydroxy bursehernin inhibits the expression of inducible nitric oxide synthase through NF-kB DNA binding suppression. Nitric Oxide 16 274-285
Pokharel YR, Yang JS, Kim JY, Oh HW, Jeong HG, Woo ER and Kang KW (2006) Potent inhibition of the inductions of inducible nitric oxide synthase and cyclooxygenase-2 by taiwaniaflavone. Nitric Oxide 15 217-225
Polavarapu R, Gongora MC, Winkles JA and Yepes M (2005) Tumor necrosis factor-like weak inducer of apoptosis increases the permeability of the neurovascular unit through nuclear factor-kB pathway activation. Journal of Neuroscience 25 10094-10100
Pold M, Zhu LX, Sharma S, Burdick MD, Lin Y, Lee PP, Pold A, Luo J, Krysan K, Dohadwala M, Mao JT, Batra RK, Strieter RM and Dubinett SM (2004) Cyclooxygenase-2-Dependent expression of angiogenic CXC chemokines ENA-78/CXC ligand (CXCL) 5 and interleukin-8/CXCL8 in human non-small cell lung cancer. Cancer Research 64 1853-1860
Poleganov MA, Bachman M, Pfeilschifter J and Muhl H (2008) Genome-wide analysis displays marked induction of EBI3/IL-27B in IL-18-activated AML-derived KG1 cells: Critical role of two kappaB binding sites in the human EBI3 promotor. Molecular Immunology in press
Polek TC, Talpaz M and Spivak-Kroizman T (2006) The TNF receptor, RELT, binds SPAK and uses it to mediate p38 and JNK activation. Biochemical and Biophysical Research Communications in press
Polentarutti N, Penton Rol G, Muzio M, Bosisio D, Camnasio M, Riva F, Zoja C, Benigni A, Tomasoni S, Vecchi A, Garlanda C and Mantovani A (2003) Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8/SIGIRR. European Cytokine Network 14 211-218
Politi C, Del Turco D, Sie JM, Golinski PA, Tegeder I, Deller T and Schultz C (2007) Accumulation of phosphorylated IkBa and activated IKK in nodes of Ranvier. Neuropathology and Applied Neurobiology in press
Poljak L, Carlson L, Cunningham K, Kosco-Vilbois MH and Siebenlist U (1999) Distinct activities of p52/NF-kB required for proper secondary lymphoid organ microarchitecture: functions enhanced by Bcl-3. Journal of Immunology 163 6581-6588
Poljakovic M, Nygren JM and Persson K (2003) Signalling pathways regulating inducible nitric oxide synthase expression in human kidney epithelial cells. European Journal of Pharmacology 469 21-28
Poljakovic M, Svensson L and Persson K (2005) The influence of uropathogenic Escherichia coli and proinflammatory cytokines on the inducible nitric oxide synthase response in human kidney epithelial cells. Journal of Urology 173 1000-1003
Polk WW, Ellis ME, Kushleika JV, Simmonds PL and Woods JS (2007) RhoA regulation of NF-{kappa}B activation is mediated by Cox-2-dependent feedback inhibition of IKK in kidney epithelial Cells.
American Journal of Physiology: Cell Physiology in press
Pollara G, Handley ME, Kwan A, Chain Bm and Katz DR (2006) Autocrine type I interferon amplifies dendritic cell responses to lipopolysaccharide via the nuclear factor-kB/p38 pathways.
Scandinavian Journal of Immunology 63 151-154
Pollara G, Jones M, Handley ME, Rajpopat M, Kwan A, Coffin RS, Foster G, Chain B and Katz DR (2004) Herpes simplex virus type-1-induced activation of myeloid dendritic cells: the roles of virus cell interaction and paracrine type I IFN secretion. Journal of Immunology 173 4108-4119
Pollara G, Katz DR and Chain BM (2005) LIGHTing up dendritic cell activation: Immune regulation and viral exploitation. Journal of Cell Physiology 205 161-162
Pollard HB, Ji XD, Jozwik C and Jacobowitz DM (2005) High abundance protein profiling of cystic fibrosis lung epithelial cells. Proteomics 5 2210-2226
Pollet I, Opina CJ, Zimmerman C, Leong KG, Wong F and Karsan A (2003) Bacterial lipopolysaccharide directly induces angiogenesis through TRAF6-mediated activation of NF-kB and c-Jun N-terminal kinase. Blood 102 1740-1742
Pollet S, Bottex-Gauthier C, Li M, Potier P, Favier A and Vidal D (2002) Insight into some of the signaling pathways triggered by a lipid immunomodulator. Immunopharmacol Immunotoxicol 24 527-546
Pollock G, Pennypacker KR, Memet S, Israel A and Saporta S (2005) Activation of NF-kB in the mouse spinal cord following sciatic nerve transection. Experimental Brain Research 165 470-477
Polumuri SK, Toshchakov VY and Vogel SN (2007) Role of phosphatidylinositol-3 kinase in transcriptional regulation of TLR-induced IL-12 and IL-10 by Fcgamma receptor ligation in murine macrophages. Journal of Immunology 179 236-246
Polyak SJ, Morishima C, Shuhart MC, Wang CC, Liu Y and Lee DY (2007) Inhibition of T-cell inflammatory cytokines, hepatocyte NF-kB signaling, and HCV infection by standardized silymarin.
Gastroenterology 132 1925-1936
Poma P, Notarbartolo M, Labbozzetta M, Maurici A, Carina V, ALaimo A, RIzzi M, Simoni D and D’Alessandro N (2007) The antitumor activities of curcumin and of its isoxazole analogue are not affected by multiple gene expression changes in an MDR model of the MCF-7 breast cancer cell line: analysis of the possible molecular basis. International Journal of Molecular Medicine 20 329-335
Poma P, Notarbartalo M, Labbozzetta M, Sanguedolce R, Alaimo A, Carina V, Maurici A, Cusimano A< Cervello M and D’Alessandro N (2006) Antitumor effects of the novel NF-kB inhibitor dehydroxymethyl-epoxyquinomicin on human hepatic cancer cells: analysis of synergy with cisplatin and of possible correlation with inhibition of pro-survival genes and IL-6 production.International Journal of Oncology 28 923-930
Pomerantz JL, Denny EM and Baltimore D (2002) CARD11 mediates factor-specific activation of NF-kB by the T cell receptor complex. EMBO Journal 21 5184-5194
Pomerantz JL and Baltimore D (2002) Two pathways to NF-kB. Molecular Cell 10 693-695
Pommier Y, Sordet O, Antony S, Hayward RL and Kohn KW (2004) Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks. Oncogene 23 2934-2949
Pompermayer K, Souza DG, Lara GG, Silveira KD, Cassali GD, Andrade AA, Bonjardim CA, Passaglio KT, Assreuy J, Cunha FQ, Vieira MA and Teixeira MM (2005) The ATP-sensitive potassium channel blocker glibenclamide prevents renal ischemia/reperfusion injury in rats. Kidney International 67 1785-1796
Ponnappan S, Cullen SJ and Pnnappan U (2005) Constitutive degradation of IkB-a in human T lymphocytes is mediated by calpain.Immunity & Ageing 2 15
Ponnappan S, Uken-Trebilcock G, Lindquist M and Ponnappan U (2004) Tyrosine phosphorylation-dependent activation of NFkB is compromised in T cells from the elderly. Experimental Gerontology 39 559-566
Ponnappan U, Yull FE and Soderberg LS (2004) Inhaled isobutyl nitrite inhibited macrophage inducible nitric oxide by blocking NFkB signaling and promoting degradation of inducible nitric oxide synthase-2. International Immunopharmacology 4 1075-1082
Pons J, Evrard-Todeschi N, Bertho G, Gharbi-Benarous J, Sonois V, Benarous R and Griault JP )2007) Structural studies on 24P-IkBa peptide derived from a human IkB-a protein related to the inhibition of the activity of the transcription factor NF-kB.Biochemistry in press
Ponton A, Clément M-V and Stamenkovic I (1996) The CD95 (APO-1/Fas) receptor activates NF-kB independently of its cytotoxic function. Journal of Biological Chemistry 271 8991-8995
Pontrelli P, Ursi M, Ranieri E, Capobianco C, Schena FP, Gesualdo L and Grandaliano G (2006) CD40L proinflammatory and profibrotic effects on proximal tubular epithelial cells: role of NF-kB and Lyn. Journal of the American Society of Nephrology 17 627-636
Poole E, He B, Lamb RA, Randall RE and Goodbourn S (2002) The V proteins of simian virus 5 and other paramyxoviruses inhibit induction of interferon-beta. Virology 303 33-46
Poole JC, Thain A, Perkins ND and Roninson IB (2004) Induction of transcription by p21(Waf1/Cip1/Sdi1): Role of NFkB and effect of non-steroidal anti-inflammatory drugs. Cell Cycle 3 931-940
Popescu FD (2004) New asthma drugs acting on gene expression. Journal of Cellular and Molecular Medicine 7 475-486
Popescu FD (2005) Antisense- and RNA interference-based therapeutic strategies in allergy.
Journal of Cellular and Molecular Medicine 9 840-853
Popkin DL and Virgin HW 4th (2003) Murine cytomegalovirus infection inhibits tumor necrosis factor alpha responses in primary macrophages. Journal of Virology 77 10125-10130
Popov I, Li M, Zheng X, Sun H, Zhang X, Feng B, Vladau C, Zhong R, Garcia B, Strejan G, Inman RD, Min WP, Ichim TE and Suzuki M (2006) Preventing autoimmune arthritis using antigen-specific immature dendritic cells: a novel tolerogenic vaccine.Arthritis Research and Therapy 8 R141
Popovic M, Laumonnier Y, Burysek L, Syrovets T and Simmet T (2008) Thrombin-induced expression of endothelial CX3CL1 potentiates monocyte CCL2 production and transendothelial migration. Journal of Leukocyte Biology in press
Poppema S (2005) Immunobiology and pathophysiology of Hodgkin lymphomas. Hematology (American Society of Hematology Education Program) 231-238
Porcile C, Piccioli P, Stanzione S, Bajetto A, Bonavia R, Barbero S, Florio T and Schettinia G (2002) Proteasome inhibitors induce cerebellar granule cell death: inhibition of nuclear factor-kB activation. Annals of the New York Academy of Sciences 973 402-413
Porcile C, Stanzione S, Piccioli P, Bajetto A, Barbero S, Bisaglia M, Bonavia R, Florio T and Schettini G (2003) Pyrrolidinedithiocarbamate induces apoptosis in cerebellar granule cells: involvement of AP-1 and MAP kinases. Neurochemistry International 43 31-38
Porkka-Heiskanen T, Alanko L, Kalinchuk A and Stenberg D (2002) Adenosine and sleep. Sleep Med Rev 6 321-332
Portaleone D, Taroni F, Micheli S, Moioli M, Pedrazzini A, Cognizzoli P and Carnelli V (2007) A protocol proposal for the stadiation of Incontinentia Pigmenti in pediatric age. Minerva Pediatrics 59 255-265
Porter DW, Wolfarth M, Young SH, Rao MK, Meighan T, Barger M, ANdrew ME and Huffman LJ (2007) PGJ2 Inhibition of LPS-induced inflammatory mediator expression from rat alveolar macrophages. Journal of Toxicology and Environmental Health A 70 1967-1976
Portis T, Harding JC and Ratner L (2001) The contribution of NF-kB activity to spontaneous proliferation and resistance to apoptosis in human T-cell leukemia virus type 1 Tax-induced tumors. Blood 98 1200-1208
Posadas I, De Rosa S, Terencio MC, Paya M and Alcaraz MJ (2003) Cacospongionolide B suppresses the expression of inflammatory enzymes and tumour necrosis factor-alpha by inhibiting nuclear factor-kB activation. British Journal of Pharmacology 138 1571-1579
Posadas I, Terencio MC, Randazzo A, Gomez-Paloma L, Paya M and Alcaraz MJ (2003) Inhibition of the NF-kB signaling pathway mediates the anti-inflammatory effects of petrosaspongiolide M. Biochemical Pharmacology 65 887-895
Poser I, Golob M, Buettner R and Bosserhoff AK (2003) Upregulation of HMG1 leads to melanoma inhibitory activity expression in malignant melanoma cells and contributes to their malignancy phenotype. Molecular and Cellular Biology 23 2991-2998
Post A, Holsboer F and Behl C (1998) Induction of NF-kB activity during haloperidol-induced oxidative toxicity in clonal hippocampal cells: suppression of NF-kB and neuroprotection by antioxidants. Journal of Neuroscience 18 8236-8246
Potena L, Frascaroli G, Grigioni F, Lazzarotto T, Magnani G, Tomasi L, Coccolo F, Gabrielli L, Magelli C, Landini MP and Branzi A (2004) Hydroxymethyl-glutaryl coenzyme A reductase inhibition limits cytomegalovirus infection in human endothelial cells. Circulation 109 532-536
Poteser M and Wakabayashi I (2004) Serum albumin induces iNOS expression and NO production in RAW 267.4 macrophages. British Journal of Pharmacology 143 143-151
Potmesil P, Holy A, Kmonickova E, Krizkova J and Zidek Z (2006) Acyclic nucleoside phosphonate antivirals activate gene expression of monocyte chemotactic protein 1 and 3. Journal of Biomedical Science 14 59-66
Potmesil P, Krecmerova M, Kmonickova E, Holy A and Zidek Z (2006) Nucleotide analogues with immunobiological properties: 9-[2-Hydroxy-3-(phosphonomethoxy)propyl]-adenine (HPMPA), -2,6-diaminopurine (HPMPDAP), and their N(6)-substituted derivatives.European Journal of Pharmacology 540 191-199
Potrovita I, Zhang W, Burkly L, Hahm K, Lincecum J, Wang MZ, Maurer MH, Rossner M, Schneider A and Schwaninger M (2004) Tumor necrosis factor-like weak inducer of apoptosis-induced neurodegeneration. Journal of Neuroscience 24 8237-8244
Potteaux S, Deleuze V, Merval R, Bureau MF, Esposito B, Scherman D, Tedgui A and Mallat Z (2006) In vivo electrotransfer of interleukin-10 cDNA prevents endothelial upregulation of activated NF-kB and adhesion molecules following an atherogenic diet. European Cytokine Network 17 13-18
Potter DA, Larson CJ, Eckes P, Schmid RM, Nabel GJ, Verdine GL and Sharp PA (1993) Purification of the MHC class I transcription factor H2TF1: the full-length product of the nfkb2 gene. Journal of Biological Chemistry 268 18882-18890
Potter JJ, Rennie-Tankersley L and Mezey E (2003) Endotoxin enhances liver alcohol dehydrogenase by action through upstream stimulatory factor but not by nuclear factor-kB. Journal of Biological Chemistry 278 4353-4357
Potula R, Ramirez SH, Knipe B, Leibhart J, Schall K, Heilman D, Morsey B, Mercer A, Papugani A, Dou H, Persidsky Y (2008) Peroxisome proliferator-activated receptor-g activation suppresses HIV-1 replication in an animal model of encephalitis. AIDS22 1539-1549
Poulaki V, Iliaki E, Mitsiades CS, Mantas YP, Bula DV, Gragoudas ES and Miller JW (2007) Inhibition of Hsp90 attenuates inflammation in endotoxin-induced uveitis. FASEB Journal in press
Poulaki V, Joussen AM, Mitsiades N, Mitsiades CS, Iliaki EF and Adamis AP (2004) Insulin-like growth factor-I plays a pathogenetic role in diabetic retinopathy. American Journal of Pathology 165 457-469
Poulaki V, Mitsiades CS, Joussen AM, Lappas A, Kirchhof B and Mitsiades N (2002) Constitutive nuclear factor-kB activity is crucial for human retinoblastoma cell viability. American Journal of Pathology 161 2229-2240
Poulaki V, Mitsiades CS,Kotoula V, Negri J, McMillin D, Miller JW and Mitsiades N (2007) The proteasome inhibitor bortezomib induces apoptosis in human retinoblastoma cell lines in vitro.
Investigative Ophthalmology & Visual Science 48 4706-4719
Poulaki V, Mitsiades CS, McMullan C, Fanourakis G, Negri J, Goudopoulou A, Halikias IX, Voutsinas G, Tseleni-Balafouta S, Miller JW and Mitsiades N (2005) Human retinoblastoma cells are resistant to apoptosis induced by death receptors: role of caspase-8 gene silencing. Invest Ophthalmol Vis Sci 46 358-366
Powis G (1994) Signalling pathways as targets for anticancer drug development. Pharmacology and Therapeutics 62 57-95
Powis SH (1998) Lessons from an age-old war. Nature Medicine 4 887-888
Powell JD, Boodoo S and Horton MR (2004) Identification of the molecular mechanism by which TLR ligation and IFN-g synergize to induce MIG. Clinical and Developmental Immunology 11 77-85
Powell PP, Dixon LK and Parkhouse RME (1996) An IkB homolog encoded by African swine fever virus provides a novel mechanism for downregulation of proinflammatory cytokine responses in host macrophages. Journal of Virology 70 8527-8533
Power MR, Li B, Yamamoto M, Akira S and Lin TJ (2007) A role of Toll-IL-1 receptor domain-containing adaptor-inducing IFN-b in the host response to Pseudomonas aeruginosa lung infection in mice. Journal of Immunology 178 3170-3176
Power MR, Peng Y, Maydanski E, Marshall JS and Lin TJ (2004) The development of early host response to Pseudomonas aeruginosa lung infection is critically dependent on MyD88 in mice. Journal of Biological Chemistry 279 49315-49322
Powers KA, Kapus A, Khadaroo RG, He R, Marshall JC, Lindsay TF and Rotstein OD (2003) Twenty-five percent albumin prevents lung injury following shock/resuscitation. Critical Care Medicine 31 2355-2363
Powers KA, Zurawska J, Szaszi K, Khadaroo RG, Kapus A and Rotstein OD (2005) Hypertonic resuscitation of hemorrhagic shock prevents alveolar macrophage activation by preventing systemic oxidative stress due to gut ischemia/reperfusion. Surgery 137 66-74
Poylin V, Fareed MU, O’Neal P, Alamdari N, Reilly N, Menconi M and Hasselgren PO (2008) The NF-kappaB inhibitor curcumin blocks sepsis-induced muscle proteolysis. Mediators of Inflammation 2008 317851
Poynter ME, Cloots R, van Woerkom T, Butnor KJ, Vacek P, Taatjes DJ, Irvin CG and Janssen-Heininger YM (2004) NF-kB activation in airways modulates allergic inflammation but not hyperresponsiveness. Journal of Immunology 173 7003-7009
Poynter ME and Daynes RA (1998) Peroxisome proliferator-activated receptor alpha activation modulates cellular redox status, represses nuclear factor kB signaling, and reduces inflammatory cytokine production in aging. Journal of Biological Chemistry 273 32833-32841
Poynter ME, Irvin CG and Janssen-Heininger YM (2003) A prominent role for airway epithelial NF-kB activation in lipopolysaccharide-induced airway inflammation. Journal of Immunology 170 6257-6265
Pozarowski P, Halicka DH and Darzynkiewicz Z (2003) Cell cycle effects and caspase-dependent and independent death of HL-60 and Jurkat cells treated with the inhibitor of NF-kB parthenolide. Cell Cycle 2 377-383
Pozarowski P, Halicka DH and Darzynkiewicz Z (2003) NF-kB inhibitor sesquiterpene parthenolide induces concurrently atypical apoptosis and cell necrosis: Difficulties in identification of dead cells in such cultures. Cytometry 54A 118-124
Pozarowski P, Holden E and Darzynkiewicz Z (2006) Laser scanning cytometry: principles and applications. Methods in Molecular Biology 319 165-192
Pozo-Guisado E, Merino JM, Mulero-Navarro S, Lorenzo-Benayas MJ, Centeno F, Alvarez-Barrientos A and Salguero PM (2005) Resveratrol-induced apoptosis in MCF-7 human breast cancer cells involves a caspase-independent mechanism with downregulation of Bcl-2 and NF-kB. International Journal of Cancer 115 74-84
Prabhakaran K, Ghosh D, Chapman GD and Gunasekar PG (2008) Molecular mechanism of manganese exposure-induced dopaminergic toxicity. Brain Research Bulletin 76 361-367
Prabhakaran K, Li L, Borowitz JL and Isom GE (2006) Inducible nitric oxide synthase up-regulation and mitochondrial glutathione depletion mediate cyanide-induced necrosis in mesencephalic cells. Journal of Neuroscience Research 84 1003-1011
Pradeep CR and Kuttan G (2004) Piperine is a potent inhibitor of nuclear factor-kB (NF-kB), c-Fos, CREB, ATF-2 and proinflammatory cytokine gene expression in B16F-10 melanoma cells. International Immunopharmacology 4 1795-1803
Pradillo JM, Romera C, Hurtado O, Cardenas A, Moro MA, Leza JC, Davalos A, Castillo J, Lorenzo P and Lizasoain I (2005) TNFR1 upregulation mediates tolerance after brain ischemic preconditioning. Journal of Cerebral Blood Flow and Metabolism 25 193-203
Praga M and Morales E (2002) Renal damage associated with proteinuria. Kidney International 62 42-46
Prajapati S, Tu Z, Yamamoto Y and Gaynor RB (2006) IKKa regulates the mitotic phase of the cell cycle by modulating Aurora A phosphorylation. Cell Cycle 5 2371-2380
Prajapati S, Verma U, Yamamoto Y, Kwak YT and Gaynor RB (2003) Protein phosphatase 2Cbeta association with the IKK complex is involved in regulating NF-kB activity. Journal of Biological Chemistry 279 1739-1746
Prakash O, Swamy OR, Peng X, Tang ZY, Li L, Larson JE, Cohen JC, Gill J, Farr G, Wang S and Samaniego F (2005) Activation of Src kinase Lyn by the Kaposi sarcoma-associated herpes virus K1 protein: implications for lymphomagenesis. Blood 105 3987-3994
Prasad AS (2007) Zinc: mechanisms of host defense. Journal of Nutrition 137 1345-1349
Prasad AS (2008) Clinical, immunological, anti-inflammatory and antioxidant roles of zinc. Experimental Gerontology in press
Prasad AS (2008) Zinc in human health: effect of zinc on immune cells. Molecular Medicine in press
Prasad AS, Bao B, Beck FW, Kucuk O and Sarkar FH (2004) Antioxidant effect of zinc in humans. Free Radical Biology and Medicine 37 1182-1190
Prasad AS, Bao B, Beck FW and Sarkar FH (2001) Zinc activates NF-kB in HUT-78 cells. J Lab Clin Med 138 250-256
Prasad AS, Bao B, Beck FW and Sarkar FH (2006) Correction of interleukin-2 gene expression by in vitro zinc addition to mononuclear cells from zinc-deficient human subjects: A specific test for zinc deficiency in humans. Translational Research148 325-333
Prasad R, Giri S, Nath N, Singh I and Singh AK (2005) Inhibition of phosphoinositide 3 kinase-Akt (protein kinase B)-nuclear factor-kB pathway by lovastatin limits endothelial-monocyte cell interaction. Journal of Neurochemistry 94 204-214
Prasad R, Giri S, Nath N, Singh I and Singh AK (2006) 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside attenuates experimental autoimmune encephalomyelitis via modulation of endothelial-monocyte interaction. Journal of Neuroscience Research 84 614-625
Prasad R, Giri S, Nath N, Singh I and Singh AK (2007) GSNO attenuates EAE disease by S-nitrosylation-mediated modulation of endothelial-monocyte interactions. Glia 55 65-77
Pratt MA, Bishop TE, White D, Yasvinski G, Menard M, Niu MY and Clarke R (2003) Estrogen withdrawal-induced NF-kB activity and bcl-3 expression in breast cancer cells: roles in growth and hormone independence. Molecular and Cellular Biology 23 6887-6900
Prawan A, Kundu JK and Surh AJ (2005) Molecular basis of heme oxygenase-1 induction: implications for chemoprevention and chemoprotection. Antioxidants and Redox Signaling 7 1688-1703
Preciado D, Caicedo E, Jhanjee R, Silver R, Harris G, Juhn SK, Choo DI and Ondrey F (2005) Pseudomonas aeruginosa lipopolysaccharide induction of keratinocyte proliferation, NF-kB, and Cyclin D1 is inhibited by indomethacin. Journal of Immunology 174 2964-2973
Preciado D, Lin J, Wuertz B and Rose M (2007) Cigarette smoke activates NFkB and induces Muc5b expression in mouse middle ear cells. Laryngoscope in press
Preiss S, Thompson A, Chen X, Rodgers S, Markovska V, Desmond P, Visvanathan K, Li K, Locarnini S, Revill P (2008) Characterization of the innate immune signalling pathways in hepatocyte cell lines. Journal of Viral Hepatitis in press
Premraj A, Sreekumar E, Nautiyal B and Rasool TJ (2006) Molecular characterization and prokaryotic expression of buffalo (Bubalus bubalis) interleukin-6. Molecular Immunology 43 202-209
Prendes M, Zheng Y and Beg AA (2003) Regulation of developing B cell survival by RelA-containing NF-kB complexes. Journal of Immunology 171 3963-3969
Preston GA, Zarella CS, Pendergraft WF 3rd, Rudolph EH, Yang JJ, Sekura SB, Jennette JC and Falk RJ (2002) Novel effects of neutrophil-derived proteinase 3 and elastase on the vascular endothelium involve in vivo cleavage of NF-kB and proapoptotic changes in JNK, ERK, and p38 MAPK signaling pathways. Journal of the American Society of Nephrology 13 2840-2849
Preusch MR, Bea F, Yang SH, Kreuzer J, Isermann B, Pedal I, Rosenfeld ME, Katus HA and Blessing E (2007) Long-term administration of 3-deazaadenosine does not alter progression of advanced atherosclerotic lesions in apolipoprotein E-deficient mice. Journal of Cardiovascular Pharmacology 50 206-212
Prickett TD, Ninomiya-Tsuji J, Broglie P, Muratore TL, Shabanowitz J, Hunt DF and Brautigan DL (2008) TAB4 stimulates TAK1-TAB1 phosphorylation and binds polyubiquitin to direct signaling to NF-kB. Journal of Biological Chemistry 283 19245-19254
Pries R, Hogrefe L, Xie L, Frenzel H, Brocks C, Ditz C and Wollenberg B (2008) Induction of c-Myc-dependent cell proliferation through toll-like receptor 3 in head and neck cancer. International JOurnal of Molecular Medicine 21 209-215
Primrose DA, Chaudhry S, Johnson AG, Hrdlicka A, Schindler A, Tran D and Foley E (2007) Interactions of DNR1 with the apoptotic machinery of Drosophila melanogaster. Journal of Cell Science 120 1189-1199
Prince A (2006) Flagellar activation of epithelial signaling. American Journal of Respiratory Cell and Molecular Biology 34 548-551
Prince JM, Levy RM, Yang R, Mollen KP, Fink MP, Vodovotz Y and Billiar TR (2006) Toll-like receptor-4 signaling mediates hepatic injury and systemic inflammation in hemorrhagic shock.
Journal of the American College of Surgeons 202 407-417
Prince LS, Okoh VO, Moninger TO and Matalon S (2004) Lipopolysaccharide increases alveolar type II cell number in fetal mouse lungs through Toll-like receptor 4 and NF-kB. American Journal of Physiology: Lung Cell and Molecular Physiology 287 L999-L1006
Prince S, Keating S, Fielding C, Brennan P, Floettmann E and Rowe M (2003) Latent Membrane Protein 1 inhibits Epstein-Barr virus lytic cycle induction and progress via different mechanisms. Journal of Virology 77 5000-5007
Pritzker LB, Scatena M and Giachelli CM (2004) The role of osteoprotegerin and TNF-related apoptosis inducting ligand in human microvascular endotherlial cell survival. Molecular Biology of the Cell 15 2834-2844
Proksch P, Giaisi M, Treiber MK, Palfi K, Merling A, Spring H, Krammer PH, Li-Weber M (2005) Rocaglamide derivatives are immunosuppressive phytochemicals that target NF-AT activity in T cells. Journal of Immunology 174 7075-7084
Prosch S, Priemer C, Hoflich C, Liebenthaf C, Babel N, Kruger DH and Volk HD (2003) Proteasome inhibitors: a novel tool to suppress human cytomegalovirus replication and virus-induced immune modulation. Antiviral Research 8 555-567
Prösch S, Staak K, Stein J, Liebenthal C, Stamminger T, Volk H-D and Krüger DH (1995) Stimulation of human cytomegalovirus IE enhancer/promoter in HL60 cells by TNFa is mediated via induction of NF-kB. Virology 208 197-206
Prosch S, Wuttke R, Kruger DH and Volk HD (2002) NF-kB–a potential therapeutic target for inhibition of human cytomegalovirus (re)activation? Biol Chem 383 1601-1609
Prothmann C, Armstrong NJ, Roth S and Rupp RA (2006) Vertebrate Rel proteins exhibit dorsal-like activities in early Drosophila embryogenesis. Developmental Dynamics 235 949-957
Proud D, Sanders SP and Wiehler S (2004) Human rhinovirus infection induces airway epithelial cell production of human beta-defensin 2 both in vitro and in vivo. Journal of Immunology 172 4637-4645
Pruett SB, Fan R and Zheng Q (2003) Characterization of glucocorticoid receptor translocation, cytoplasmic IkB, nuclear NFkB, and activation of NFkB in T lymphocytes exposed to stress-inducible concentrations of corticosterone in vivo. International Immunopharmacology 3 1-16
Pruett SB, Schwab C, Zheng Q and Fan R (2004) Suppression of innate immunity by acute ethanol administration: a global perspective and a new mechanism beginning with inhibition of signaling through TLR3. Journal of Immunology 173 2715-2724
Pruett SB, Zheng Q, Schwab C and Fan R (2005) Sodium methyldithiocarbamate inhibits MAP kinase activation Tthrough Toll-like receptor 4, alters cytokine production by mouse peritoneal macrophages, and suppresses innate immunity. Toxicological Sciences 87 75-85
Przetak M, Chow J, Cheng H, Rose J, Hawkins LD and Ishizaka ST (2003) Novel synthetic LPS receptor agonists boost systemic and mucosal antibody responses in mice. Vaccine 21 961-970
Psarra AM and Sekeris CE (2007) Nuclear receptors and other nuclear transcription factors in mitochondria: regulatory molecules in a new environment. Biochimica et Biophysica Acta in press
Pu Q, Amiri F, Gannon P and Schiffrin EL (2005) Dual angiotensin-converting enzyme/neutral endopeptidase inhibition on cardiac and renal fibrosis and inflammation in DOCA-salt hypertensive rats. Journal of Hypertension 23 401-409
Pu WT, Ma Q and Izumo S (2003) NFAT transcription factors are critical Survival factors that inhibit cardiomyocyte apoptosis during phenylephrine stimulation in vitro. Circulation Research 92 725-731
Puca A, Fiume G, Palmieri C, Trimboli F, Olimpico F, Scale G and Quinto I (2007) IkB-a represses the transcriptional activity of the NIV-1 Tat transactivator by promoting its nuclear export. Journal of Biological Chemistry 282 37146-37157
Puccetti P and Fallarino F (2007) Generation of T cell regulatory activity by plasmacytoid dendritic cells and tryptophan catabolism. Blood Cells, Molecules & Disease in press
Puccetti P and Grohmann U (2007) IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-kB activation. Nature Reviews Immunology in press
Puel A, Picard C, Ku CL, Smahi A and Casanova JL (2004) Inherited disorders of NF-kB-mediated immunity in man. Current Opinion in Immunology 16 34-41
Puel A, Reichenbach J, Bustamante J, Ku CL, Feinberg J, Doffinger R, Bonnet M, Filipe-Santos O, Beaucoudrey L, Durandy A, Horneff G, Novelli F, Wahn V, Smahi A, Israel A, Niehues T and Casonva JL (2006) The NEMO mutation creating the most-upstream premature stop codon is hypomorphic because of a reinitiation of translation. American Journal of Human Genetics 78 691-701
Puel A, Yang K, Ku CL, von Bernuth H, Bustamante J, Santos OF, Lawrence T, Chang HH, Al-Mousa H, PIcard C and Casonova JL (2005) Heritable defects of the human TLR signalling pathways. Journal of Endotoxin Research 11 220-224
Pugh ND, Balachandran P, Lata H, Dayan FE, Joshi V, Bedir E, Makino T, Moraes R, Khan I and Pasco DS (2005) Melanin: dietary mucosal immune modulator from Echinacea and other botanical supplements. International Immunopharmacology 5 637-647
Puig-Kroger A, Muniz-Pello O, Selgas R, Criado G, Bajo MA, Sanchez-Tomero JA, Alvarez V, Del Peso G, Sanchez-Mateos P, Holmes C, Faict D, Lopez-Cabrera M, Madrenas J and Corbi AL (2003) Peritoneal dialysis solutions inhibit the differentiation and maturation of human monocyte-derived dendritic cells: effect of lactate and glucose-degradation products. Journal of Leukocyte Biology 73 482-492
Pulai JI, Chen H, Im HJ, Kumar S, Hanning C, Hegde PS and Loeser RF (2005) NF-kB mediates the stimulation of cytokine and chemokine expression by human articular chondrocytes in response to fibronectin fragments. Journal of Immunology 174 5781-5788
Pullen SS, Dan TTA, Crute JJ and Kehry MR (1999) CD40 signaling through tumor necrosis factor receptor associated factors (TRAFs): binding site specificity and activation of downstream pathways by distinct TRAFs. Journal of Biological Chemistry 274 14246-14254
Pullerits R, Bokarewa M, Jonsson IM, Verdrengh M and Tarkowski A (2005) Extracellular cytochrome c, a mitochondrial apoptosis-related protein, induces arthritis. Rheumatology 44 32-39
Pullerits R, Brisslert M, Jonsson IM and Tarkowski A (2006) Soluble receptor for advanced glycation end products triggers a proinflammatory cytokine cascade via beta2 integrin Mac-1. Arthritis and Rheumatism 54 3898-3907
Pullerits R, Jonsson IM, Verdrengh M, Bokarewa M, Andersson U, Erlandsson-Harris H and Tarkowski A (2003) High mobility group box chromosomal protein 1, a DNA binding cytokine, induces arthritis. Arthritis and Rheumitis 48 1693-1700
Pummila M, Fliniaux I, Jaatinen R, James MJ, Laurikkala J, Schneider P, Thesleff I and Mikkola ML (2007) Ectodysplasin has a dual role in ectodermal organogenesis: inhibition of Bmp activity and induction of Shh expression. Development 134 117-125
Punturieri A, Copper P, Polak T, Christensen PJ and Curtis JL (2006) Conserved nontypeable Haemophilus influenzae-derived TLR2-binding lipopeptides synergize with IFN-beta to increase cytokine production by resident murine and human alveolar macrophages. Journal of Immunology 177 673-680
Punzon C, Alcaide A and Fresno M (2003) In vitro anti-inflammatory activity of Phlebodium decumanum. Modulation of tumor necrosis factor and soluble TNF receptors. International Immunopharmacology 3 1293-1299
Pupe A, Degreef H and Garmyn M (2003) Induction of tumor necrosis factor-alpha by UVB: a role for reactive oxygen intermediates and eicosanoids. Photochemistry and Photobiology 78 68-74
Puppo F, Contini P, Ghio M and Indiveri F (2002) Soluble HLA class I molecules/CD8 ligation trigger apoptosis of CD8+ cells by Fas/Fas-ligand interaction. ScientificWorldJournal 2 421-423
Pupure J, Fernandes MA, Santos MS, Moreno AJ, Kalvinsh I, Klusa V and Oliveira Cr (2008) Mitochondria as the target for mildronate’s protective effects in azidothymidine (AZT)-induced toxicity of isolated rat liver mitochondria. Cell Biochem Funct in press
Purcell NH and Molkentin JD (2003) Is nuclear factor kB an attractive therapeutic target for treating cardiac hypertrophy? Circulation 108 638-640
Purcell NH, Tang G, Yu C, Mercurio F, DiDonato JA and Lin A (2002) Activation of NF-kB is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes. Proceedings of the National Academy of Sciences USA 98 6668-6673
Purchase HG, Ludford C, Nazerian K and Cox HW (1973) A new group of oncogenic viruses: reticuloendotheliosis, chick syncytial, duck infectious anemia and spleen necrosis viruses. Journal of the National Cancer Institute 51 489-497
Purchase HG and Witter RJ (1975) The reticuloendotheliosis viruses. Current Topics in Microbiology and Immunology (ed PK Vogt) Springer-Verlag, NY 103-124
Puri KD, Doggett TA, Huang CY, Douangpanya J, Hayflick JS, Turner M, Penninger J and Diacovo TG (2005) The role of endothelial PI3Kgamma activity in neutrophil trafficking. Blood 106 150-157
Purkerson JM, Smith RS, Pollock SJ and Phipps RP (2005) The TRAF6, but not the TRAF2/3, binding domain of CD40 is required for cytokine production in human lung fibroblasts. European Journal of Immunology 35 2920-2928
Purohit V, Russo D and Salin M (2003) Role of iron in alcoholic liver disease: introduction and summary of the symposium. Alcohol 30 93-97
Purohit V, Russo D, Salin M and Brown R (2004) Mechanisms of alcoholic pancreatitis: introduction and summary of the symposium. Pancreas 27 281-285
Puthenedam M, Williams PH, Lakshmi BS and Balakrishnan A (2007) Modulation of tight junction barrier function by outer membrane proteins of enteropathogenic Escherichia coli: Role of F-actin and junctional adhesion molecule-1. Cell Biol International in press
Puthia MK, Lu J and Tan KS (2007) Blastocystis contains cysteine proteases that mediate interleukin-8 response from human intestinal epithelial cells in a NFkB-dependent manner. Eukarytoic Cell in press
Putnins EE, Sanaie AR, Wu Q and Firth JD (2002) Induction of keratinocyte growth factor 1 expression by lipopolysaccharide is regulated by CD-14 and Toll-like receptors 2 and 4. Infection and Immunity 70 6541-6548
Puto LA and Reed JC (2008) Daxx represses RelB target promoters via DNA methyltransferase recruitment and DNA hypermethylation. Genes & Development 22 998-1010
Pyatt DW, Gruntmeir J, Stillman WS and Irons RD (1998) Dimethyldithiocarbamate inhibits in vitro activation of primary human CD4+ T lymphocytes. Toxicology 28 83-90
Pyatt DW, stillman WS, irons RD (1998) Hydroquinone, a reactive metabolite of benzene, inhibits NF-kB in primary human CD4+ T Lymphocytes. Toxicology and applied Pharmacology 149 178-184
Pye J, Ardeshirpour F, McCain A, Bellinger DD, Merricks E, Adams J, Elliott PJ, Pien C, Fischer TH, Baldwin AS and Nichols TC (2003) Proteasome inhibition ablates activation of NF-kB induced during myocardial reperfusion and reduces reperfusion injury. Am J Physiol Heart Circ Physiol 284 H919-H926
Pype S, Declercq W, Ibrahimi A, Michiels C, Van Rietschoten JGI, Dewulf N, de Boer M, Vandenabeele P, Huylebroeck D and Remacle JE (2000) TTRAP, a novel protein that associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor-associated factors (TRAFs), and that inhibits nuclear factor-kB activation. Journal of Biological Chemistry 275 18586-18593