Undergraduate Prerequisites: (ENGBE403 OR ENGEC401) Requires senior status. This course surveys the applications of optical science and engineering to a variety of biomedical problems, with emphasis on optical and photonics technologies that enable real, minimally-invasive clinical and laboratory applications. The course teaches only those aspects of the biology itself that are necessary to understand the purpose of the applications. The first weeks introduce the optical properties of tissue, and following lectures cover a range of topics in three general areas: 1) Optical spectroscopy applied to diagnosis of cancer and other tissue pathologies; 2) Photon migration and diffuse optical imaging of subsurface structures in tissue; and 3) new tissue imaging methods, laser tweezers and other applications of light for biomedical research. The format of this course is "semi-flipped." There are assigned readings from the required textbook, prior to each class; and half of class time will be devoted to solving problems in small groups.

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