Graduate Prerequisites: *Can^t be taken together for credit with SPH EH 768 - This course designed to introduce the basic concepts of toxicology to students from multiple fields and disciplines. The objectives of the first part of the course are to detail the routes of exposure to xenobiotics (chemicals and drugs) and to trace the pathways through which xenobiotics are absorbed, metabolized, distributed, excreted and biomonitored. In the second section of the course, we examine the effects of molecular/cellular changes on the function of key organ systems. Students are also introduced to regulatory toxicology and food toxicology. At the completion of the course students are expected to have an extensive toxicology vocabulary and a working knowledge of: 1) general toxicological principles, 2) inter-species and inter-individual differences in responses to toxicants, 3) the effects of several key toxicants on the normal function of several organ systems, and 4) the basic approach to regulatory toxicology. The overall objective of this course is to provide the student with an introduction to the language and principles of toxicology such that these principles may be applied to public health situations, as well as to efforts to improve sustainability and reduce toxics use, and be communicated to the general public.

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