Connors and Colleagues Publish Findings in ATTRwt Amyloidosis Cohort
Data on the largest cohort of ATTRwt amyloidosis patients yet reported (n=121), referred to our institution over a 20-year observational period, were recently reported in the prestigious heart journal, Circulation. The publication, entitled “Heart failure due to age-related cardiac amyloid disease associated with wild-type transthyretin: a prospective, observational cohort study,” was authored by Dr. Lawreen H. Connors and colleagues from the Amyloidosis Center at Boston University. These data establish the natural history of ATTRwt, provide statistical basis for the design of future interventional clinical trials, and highlight the need for more sensitive diagnostic tests and disease-specific treatments for this disease. For more information, see Circulation, 133:282-290, 2016.