Brian Cleary

Assistant Professor of Computing & Data Sciences + Biology + Biomedical Engineering

Brian Cleary is an assistant professor in the Faculty of Computing & Data Sciences (CDS) and a core faculty member in the Bioinformatics Program. Brian also holds appointments in the Biology and Biomedical Engineering departments, and the Biological Design Center (BDC) at the Rajen Kilachand Center for Integrated Life Sciences & Engineering.

Prior to joining BU, Brian was an Independent Broad Fellow at the Broad Institute of MIT and Harvard.

Brian’s work aims to move beyond predictive tasks toward theoretical understandings that change how we think and what we do. Through a truly interdisciplinary mixture of bench-side and computational research, he applies paired computational and experimental methods to efficiently study the spatial organization of gene expression in tissues; to develop and connect emerging methods in machine learning with experimental design and new systems-level theories of cellular and tissue physiology.

After completing his undergraduate studies at Caltech with dual degrees in Biology and in Business, Economics, and Management, Brian spent 8 years developing algorithms for trading of index derivatives at a couple of startups before pivoting back to academia for his doctoral studies, which he completed in 2019 with a PhD in Computational and Systems Biology from the Massachusetts Institute of Technology.

Research Interests

  • Principles of Organization in Cells and Tissues

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