The Center for Systems Neuroscience is comprised of over 80 faculty.

Our faculty represent multiple colleges and departments within Boston University, on both the Charles River Campus and the Medical Campus.
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Departments (Colleges)

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90 result(s) found.

  • Michael Alosco

    Associate Professor Neurology
    Dr. Alosco completed his undergraduate studies at Providence College and he earned his doctoral degree in clinical psychology, with a focus in neuropsychology, in 2015 from Kent State University. He completed his clinical internship in neuropsychology at the VA Boston Healthcare System. In 2015, Dr. Alosco was awarded a post-doctoral fellowship at the Boston University […]
  • Jelle Atema

    Professor Emeritus, Biology
    Our labs in Boston and Woods Hole focus on three seemingly disparate research areas: chemical ecology of lobsters, navigation in sharks, and dispersal in larval reef fishes. These efforts are linked by a common theme: understanding how marine animals sense their environment, how they use this information to make decisions leading to food and mates […]
  • Rhoda Au

    Professor of Anatomy & Neurobiology
    Rhoda Au is a Professor of Anatomy & Neurobiology, Neurology, and Epidemiology at Boston University Schools of Medicine and Public. She serves as one of the PIs of the Framingham Heart Study - Brain Aging Program and is also the Director of Neuropsychology. She is also Director of Global Cohort Development for the Davos Alzheimer’s […]
  • John Baillieul

    Distinguished Professor, Engineering
    Prof. Baillieul focuses on robotics, the control of mechanical systems, and mathematical system theory. His work in the late 1980’s led to seminal papers on motion planning for kinematically redundant manipulators. Earlier work on nonlinear optimal control theory foreshadowed much of the current literature on singular Riemannian geometry. Current research focuses on extending and applying […]
  • Helen Barbas

    Professor, Health Sciences
    Our research centers on the organization of the prefrontal cortex and its role in central executive functions in primates. The goal is to investigate prefrontal pathways that interface with both excitatory and inhibitory neurons in cortical and subcortical structures that may provide the basis for the selection of relevant information and suppression of irrelevant information […]
  • Margrit Betke

    Professor, Computer Science
    Margrit Betke co-leads the Image and Video Computing Research Group. She conducts research in computer vision, in particular, the development of methods for detection, segmentation, registration, and tracking of objects in visible-light, infrared, and x-ray image data. She has worked on gesture, vehicle, and animal tracking, video-based human-computer interfaces, statistical object recognition, and medical imaging […]
  • Thomas Bifano

    Professor, Mechanical Engineering
    Prof. Bifano's research focuses on modeling, design, production, and use of micro-electro-mechanical systems (MEMS) in optical applications. He is a founder and CTO of Boston Micromachines Corporation in Cambridge, MA, a leading producer of deformable mirrors for applications in astronomy, bio-imaging, and defense.
  • David Boas

    Professor, Biomedical Engineering
    The Boas Lab develops novel optical methods and applies them principally to study the brain. We have recently expanded to complement our suite of technologies with high-speed functional ultrasound and are considering integration with photo-acoustics. Our technologies are used for measuring brain function and physiology on microscopic to macroscopic length scales and are applied in […]
  • Chand Chandrasekaran

    Assistant Professor, Anatomy & Neurobiology
    I conduct research to better understand how the brain processes complex uni- and multisensory input and generates the appropriate action at the right time. My research is guided by the ethos that understanding how the brain works will help us build better interventions for people with disabilities involving the nervous system. I expect my research […]
  • Lynne Chantranupong

    Assistant Professor of Biology
    Neurons are extremely specialized cells. They can generate intense electrical activity, maintain highly complex morphologies, and survive our entire lifetimes. Moreover, neurons are incredibly diverse, exhibiting a wide range of activity states, shapes, and sizes. These specializations confer different needs and liabilities to neurons, which they must address by adapting their molecular pathways to maintain […]
  • Jerry Chen

    Assistant Professor, Biology
    Investigating Long-Range Neocortical Networks: A longstanding goal in neuroscience is to achieve a complete understanding of the central nervous system, from the brain as a whole all the way down to individual neurons and synapses. A fundamental challenge in achieving this goal is bridging knowledge gaps impeded by the difficulty in integrating experimental measurements across […]
  • H. Steven Colburn

    Professor Emeritus, Biomedical Engineering
    Prof. Colburn’s research involves the application of signal processing, statistical communication theory, and computational modeling to the study of hearing and hearing impairments. Prof. Colburn is particularly interested in the measurement and modeling of binaural hearing performance. Specific current topics include modeling the activity of auditory brainstem neurons and measurement and modeling of spatial attributes […]
  • Alice Cronin-Golomb

    Professor, Psychological & Brain Sciences
    Prof. Cronin-Golomb conducts research on visual factors influencing high-order cognitive capacities in normal aging and age-related neurological disease, with special emphasis on object identification in Alzheimer’s disease and visuospatial function in Parkinson’s disease. Her work is supported by the National Institute of Neurological Diseases and Stroke (NIH). Prof. Cronin-Golomb’s students and research associates are conducting […]
  • Ian Davison

    Associate Professor, Biology
    Our lab studies the neural circuits that underlie perception and behavior in the olfactory system. Smell is notorious for its links to emotion and memory, and in the animal world, it is also a powerful trigger of innate behaviors like aggression, courtship, and fear. Our overall goal is to establish the circuit architecture and computational […]
  • Rachel Denison

    Assistant Professor, Psychological & Brain Sciences
    How does the brain generate our ongoing perceptual experience? The Denison Lab studies visual perception, attention, and decision making, with a focus on temporal dynamics. The lab’s research integrates behavioral measurements (psychophysics, eye tracking), neural measurements (fMRI, EEG/MEG), and computational modeling.  
  • Brian DePasquale

    Assistant Professor, Biomedical Engineering
    The DePasquale lab develops mathematical models to understand how populations of neurons perform computations to produce behavior. Broadly, we take two approaches. One is data-driven: we collaborate with experimental neuroscientists to develop tailored machine learning models of neural activity to identify the algorithms that drive behaviors such as decision-making or movement. Our second approach is […]
  • Anna Devor

    Professor, Biomedical Engineering
    We are an imaging lab. We specialize in imaging neuronal, glial, vascular, and metabolic activity in brains of living and behaving experimental animals. We also use stem-cell-derived human neuronal networks. We focus on obtaining high resolution, sensitivity and specificity optical measurements and combine optical imaging with electrophysiological recordings and functional Magnetic Resonance Imaging (fMRI). Our […]
  • Michael Economo

    Assistant Professor, Biomedical Engineering
    Prof. Economo’s laboratory studies the structure and function of the neural circuits distributed across the brain that control movement. His research leverages cutting edge optical, electrophysiological, and genetic tools for recording and manipulating neural activity during behavior and for illuminating the structure of neural circuits.
  • Uri Eden

    Professor, Mathematics & Statistics
    Prof. Eden's research focuses on developing mathematical and statistical methods to analyze neural spiking activity. This research can be divided into two categories; first a methodological component, focused on developing a statistical framework for relating neural activity to biological and behavioral signal and developing estimation algorithms, goodness-of-fit analyses, and mathematical theory that can be applied […]
  • David Farb

    Professor and Chair, Pharmacology & Experimental Therapeutics
    As head of the Laboratory of Molecular Neurobiology, Prof. Farb focuses on the identification of pharmacological treatments for disorders of learning and memory function. His research integrates existing electrophysiological, behavioral, pharmacological, and molecular genetic technologies in a novel systems-level platform for assessing the impact of cognitive enhancers such as neuroactive steroids upon fundamental hippocampal systems […]
  • Lindsay A. Farrer

    Professor of Medicine, Neurology, Ophthalmology, Epidemiology, and Biostatistics
    Dr. Lindsay Farrer is a medical geneticist at Boston University Schools of Medicine and Public Health where he is the Boston University Distinguished Professor of Genetics, Chief of Biomedical Genetics, and a Professor of Medicine, Neurology, Ophthalmology, Epidemiology, and Biostatistics. Dr. Farrer is a graduate of the University of North Carolina in Chapel Hill, received […]
  • Christopher Gabel

    Assistant Professor, Physiology & Biophysics
    Prof. Gabel's research program is focused on the development and application of femtosecond laser surgery and optical neurophysiology to the study of the nervous system of the nematode worm C. elegans. Using tightly focused pulses from an ultrafast laser, we can ablate regions of biological tissue with submicron precision, making it possible to snip individual […]
  • Jeffrey Gavornik

    Assistant Professor, Biology
    The basis of all cognitive function is communication between neurons in the brain. This communication is mediated by synaptic connections that are modified by experience to encode function. In order to get at the big question of “how the brain works,” I study how experience-driven synaptic plasticity changes local neocortical physiology. I am particularly interested […]
  • Oded Ghitza

    Research Professor, Biomedical Engineering
    Decoding speech using neuronal oscillations; Hierarchical neuronal oscillators and the basis for cortical computation; Analysis of MEG signals recorded while performing a speech perception task; Predicting consonant confusions in noise; Closed‐loop auditory models for robust automatic speech recognition; Modeling damaged cochleae using speech‐governed methodologies. Prof. Ghitza’s current research focuses on the formulation of cortical computation […]
  • Simone Gill

    Associate Professor, Occupational Therapy
    Prof. Gill investigates how individuals’ bodies and environmental demands influence walking and motor functioning across the lifespan. She uses a variety of methods to examine how children and adults modify their walking patterns to navigate through the environment. She is particularly interested in understanding how childhood and adult obesity affect the ability to adapt to […]
  • David Greer

    Chief and Professor, Neurology
    Dr. Greer’s research interests include predicting recovery from coma after cardiac arrest, brain death, and multiple stroke-related topics, including acute stroke treatment and stroke prevention. He is a leader in the Neurocritical Care Society, the Society of Critical Care Medicine, and the American Stroke Association. Additionally, he is a well-regarded and dedicated medical educator and […]
  • Stephen Grossberg

    Professor Emeritus, Mathematics and Psychology
    Prof. Grossberg develops brain models of vision and visual object recognition; audition, speech, and language; development; attentive learning and memory; cognitive information processing and social cognition; reinforcement learning and motivation; cognitive-emotional interactions; navigation; sensory-motor control and robotics; and mental disorders. These models involve many parts of the brain, ranging from perception to action, and multiple […]
  • Frank Guenther

    Professor, Speech, Language & Hearing Sciences
    Frank Guenther is professor of speech language, & hearing sciences and biomedical engineering at Boston University. His research combines theoretical modeling with behavioral and neuroimaging experiments to characterize the neural computations underlying speech. He is the originator of the DIVA model, which provides a quantitative account of the neural computations underlying speech motor control and […]
  • Xue Han

    Professor, Biomedical Engineering
    Brain disorders represent the biggest unmet medical need, with many disorders being untreatable, and most treatments presenting serious side effects. Accordingly, we are discovering design principles for novel neuromodulation therapies. We invent and apply a variety of genetic, molecular, pharmacological, optical, and electrical tools to correct neural circuits that go awry within the brain. As […]
  • David Harris

    Professor and Chair, Biochemistry
    My laboratory investigates the molecular and cellular mechanisms underlying two classes of human neurodegenerative disorders: prion and Alzheimer’s diseases. Alzheimer’s disease afflicts 5 million people in the U.S., a number that will increase dramatically as the population ages. Prion diseases are much rarer, but are of great public health concern because of the global emergence […]
  • Michael Hasselmo

    Professor, Psychological & Brain Sciences Director, Center for Systems Neuroscience
    Research in the Hasselmo Laboratory concerns the cortical dynamics of memory-guided behavior, including effects of neuromodulation and theta rhythm oscillations in cortical function. Neurophysiological techniques are used to analyze intrinsic and synaptic properties of cortical circuits in rodents and to explore the effects of modulators on these properties. Computational modeling is used to link these […]
  • Angela Ho

    Associate Professor, Biology
    Brain function requires proper networking and communication between neurons. Brain development is a complex process that involves the movement and proper connectivity of neurons. Mutations in certain genes lead to improper neuron movement and brain development that often lead to severe learning disabilities in children. We are studying a specific pathway that controls one aspect […]
  • Marc Howard

    Professor, Psychological & Brain Sciences
    We develop mathematical models of cognition and evaluate them against both behavioral and neurophysiological data, providing a bridge between cognition and systems-level neuroscience. We use a combination of mathematical, computational and behavioral tools to evaluate our hypotheses. The topics we investigate are centered on episodic memory, the ability we have to remember specific events situated […]
  • Mark Howe

    Assistant Professor, Psychological & Brain Sciences
    My laboratory seeks to identify neural circuit principles responsible for adaptively motivating, selecting, and learning actions in changing environments. We focus on the basal ganglia, a set of brain regions implicated in regulating motor and cognitive functions on multiple timescales. A range of techniques are employed including two-photon microscopy, fiber photometry, and electrophysiology in behaving […]
  • Plamen Ivanov

    Research Professor, Physics
    Prof. Ivanov's research interests include: Physiological and neural control of cardiac, locomotor, circadian, and sleep rhythms. Network physiology, particularly the interactions between integrated physiologic systems. Nonlinear dynamics and coupling, fractal and multifractal stochastic processes, stochastic feedback, and phase synchronization. Excitable media, particularly myocardial tissue. Phase transitions in physical and biological systems.
  • Robert M. Joseph

    Associate Professor, Anatomy & Neurobiology
    Prof. Joseph received his doctorate in Clinical Psychology from the University of Massachusetts in 1996. He completed postdoctoral training in developmental neuropsychology in the Department of Psychiatry at Cambridge Hospital/Harvard Medical School. Prof. Joseph has been a faculty member of the Department of Anatomy and Neurobiology since 2001. Prof. Joseph researches the neuropsychology and neurobiology […]
  • Kathleen Kantak

    Professor, Psychological & Brain Sciences
    Prof. Kantak's current research focuses on cognitive aspects of addiction-related behavior. Her overall goal is to conduct translational research using trans-species behavioral models of cognition and drug abuse and to interface her work with that of neurobiologists to understand mechanisms and with that of clinicians to improve drug addiction treatment outcomes. Using intravenous drug self-administration […]
  • Melissa Kibbe

    Associate Professor, Psychological & Brain Sciences
    Prof. Kibbe's research focuses on how infants, children, and adults represent information about objects (e.g. perceptual features, animacy, group statistics, numerosity, verbal labels).  Prof. Kibbe's lab also looks at the kinds of computations we can do with these representations, the ways in which we use these representations to guide behavior, and how cognitive systems (such […]
  • Swathi Kiran

    Professor, Speech, Language & Hearing Sciences
    The primary goal of Prof. Kiran's lab is to understand language processing and communication following a brain damage. Research in the lab makes use of Neuroimaging, neurolinguistic, psycholinguistic and neurobehavioral tools in investigating pertinent questions related to Aphasia. Some particular scholarly and practice interest of the lab are bilingual aphasia, aphasia rehabilitation, functional neuroimaging, language […]
  • Nancy Kopell

    Professor, Mathematics & Statistics
    For the last two decades, Prof. Kopell has worked on mathematical problems in neuroscience. Her current interests parallel the themes of the Cognitive Rhythms Collaborative: how does the brain produce its dynamics (physiological mechanisms), how do brain rhythms take part in cognition (sensory processing, attention, memory, motor control), and how can pathologies of brain dynamics […]
  • Mark Kramer

    Professor, Mathematics & Statistics
    Prof. Kramer's research focuses on interdisciplinary topics in mathematical neuroscience with particular emphasis on biophysical models of neural activity and data analysis techniques. He is currently interested in medical applications and networks in neuroscience.
  • Jen-Wei Lin

    Associate Professor, Biology
    My main research focus is on the biophysical events underlying transmitter release. Neurotransmitter secretion involves ion channel gating, diffusion and buffering of calcium ions, vesicular fusion as well as the mobilization and recycling of, synaptic vesicles. We use electrophysiological and imaging techniques to monitor processes underlying synaptic transmission at a high time resolution. Using the […]
  • Sam Ling

    Associate Professor, Psychological & Brain Sciences
    The glut of information available for the brain to process at any given moment necessitates an efficient attentional system that can “pick and choose” what relevant information receives prioritized processing. Interestingly, a growing body of work suggests that one powerful way that attention separates the wheat from the chaff is by altering some of the […]
  • Jennifer Luebke

    Professor, Anatomy & Neurobiology
    Prof. Luebke maintains a laboratory in which whole-cell patch-clamp and intracellular filling techniques are used to examine the electrophysiological and morphological properties of neurons in in vitro slices of monkey and transgenic mouse neocortex. Research is focused on action potential firing patterns (and underlying ionic currents), glutamatergic and GABAergic synaptic response properties and detailed dendritic […]
  • Heng-Ye Man

    Professor of Biology
    Our research interests are focused on brain development, especially neuronal migration, morphogenesis, synapse formation, glutamate receptors and synaptic plasticity. We aim to understand the cellular and molecular processes implicated in neurodegenerative diseases and developmental disorders including autism, Angelman syndrome, intellectual disability and Alzheimer’s disease. We use diverse techniques including biochemistry, immunofluorescent staining, live imaging, virus […]
  • Joe McGuire

    Associate Professor, Psychological & Brain Sciences
    My lab studies the cognitive and neural processes that facilitate human decision making. We are especially interested in how decision makers navigate challenging situations that involve delay, uncertainty, or volatility, or that seem to demand self-control. Our methodological toolbox includes behavioral experiments, computational modeling, psychophysiology, and functional neuroimaging.
  • Ann McKee

    Professor, Neurology & Pathology
    Dr. McKee completed her undergraduate studies at the University of Wisconsin and received her medical degree from the Case Western Reserve School of Medicine. She completed residency training in neurology at Cleveland Metropolitan General Hospital and fellowship training in neuropathology at Massachusetts General Hospital. She was Assistant Professor of Neuropathology at Harvard Medical School from […]
  • Maria Medalla

    Associate Professor, Anatomy & Neurobiology
    Prof. Medalla received her Ph.D. in Applied Anatomy and Physiology at the Boston University Department of Health Sciences in 2008, working with Prof. Helen Barbas to study the structure of ‘cognitive control’ pathways in the prefrontal cortex (PFC) of non-human primates. Her studies in this lab were the first to utilize triple-labeling methods for electron […]
  • Pankaj Mehta

    Professor, Physics
    I am interested in theoretical problems at the interface of physics and biology. I want to understand how large-scale, collective behaviors observed in biological systems emerge from the interaction of many individual molecular elements, and how these interactions allow cells to perform complex computations in response to environmental cues. I started a blog that I […]
  • Jerome Mertz

    Professor, Biomedical Engineering
    Prof. Mertz's lab focuses on the development and applications of novel optical microscopy techniques for biomedical imaging. Some specific topics include imaging through complex media, imaging through a single optical fiber, and oblique back-illumination microscopy.