Michael Alosco
Dr. Alosco completed his undergraduate studies at Providence College and he earned his doctoral degree in clinical psychology, with a focus in neuropsychology, in 2015 from Kent State University. He completed his clinical internship in neuropsychology at the VA Boston Healthcare System. In 2015, Dr. Alosco was awarded a post-doctoral fellowship at the Boston University […]
Rhoda Au
Rhoda Au is a Professor of Anatomy & Neurobiology, Neurology, and Epidemiology at Boston University Schools of Medicine and Public. She serves as one of the PIs of the Framingham Heart Study – Brain Aging Program and is also the Director of Neuropsychology. She is also Director of Global Cohort Development for the Davos Alzheimer’s […]
Helen Barbas
Our research centers on the organization of the prefrontal cortex and its role in central executive functions in primates. The goal is to investigate prefrontal pathways that interface with both excitatory and inhibitory neurons in cortical and subcortical structures that may provide the basis for the selection of relevant information and suppression of irrelevant information […]
Lynne Chantranupong
Neurons are extremely specialized cells. They can generate intense electrical activity, maintain highly complex morphologies, and survive our entire lifetimes. Moreover, neurons are incredibly diverse, exhibiting a wide range of activity states, shapes, and sizes. These specializations confer different needs and liabilities to neurons, which they must address by adapting their molecular pathways to maintain […]
Brian DePasquale
The DePasquale lab develops mathematical models to understand how populations of neurons perform computations to produce behavior. Broadly, we take two approaches. One is data-driven: we collaborate with experimental neuroscientists to develop tailored machine learning models of neural activity to identify the algorithms that drive behaviors such as decision-making or movement. Our second approach is […]
David Farb
As head of the Laboratory of Molecular Neurobiology, Prof. Farb focuses on the identification of pharmacological treatments for disorders of learning and memory function. His research integrates existing electrophysiological, behavioral, pharmacological, and molecular genetic technologies in a novel systems-level platform for assessing the impact of cognitive enhancers such as neuroactive steroids upon fundamental hippocampal systems […]
Jeffrey Gavornik
The basis of all cognitive function is communication between neurons in the brain. This communication is mediated by synaptic connections that are modified by experience to encode function. In order to get at the big question of “how the brain works,” I study how experience-driven synaptic plasticity changes local neocortical physiology. I am particularly interested […]
Xue Han
Brain disorders represent the biggest unmet medical need, with many disorders being untreatable, and most treatments presenting serious side effects. Accordingly, we are discovering design principles for novel neuromodulation therapies. We invent and apply a variety of genetic, molecular, pharmacological, optical, and electrical tools to correct neural circuits that go awry within the brain. As […]
Michael Hasselmo
Research in the Hasselmo Laboratory concerns the cortical dynamics of memory-guided behavior, including effects of neuromodulation and theta rhythm oscillations in cortical function. Neurophysiological techniques are used to analyze intrinsic and synaptic properties of cortical circuits in rodents and to explore the effects of modulators on these properties. Computational modeling is used to link these […]
Marc Howard
We develop mathematical models of cognition and evaluate them against both behavioral and neurophysiological data, providing a bridge between cognition and systems-level neuroscience. We use a combination of mathematical, computational and behavioral tools to evaluate our hypotheses. The topics we investigate are centered on episodic memory, the ability we have to remember specific events situated […]