“Game changer for the field of vitamin D as it relates to cancer” (Boston)—For more than 100 years, it has been believed that sunlight and vitamin D deficiency were associated with the risk for many deadly cancers including colorectal, prostate and breast. But some scientists remained skeptical that this nutrient provides any benefit for reducing […]
Discovery may lead to new approaches for repairing lungs damaged by a variety of injuries or genetic mutations (Boston)—Researchers from the Center for Regenerative Medicine (CReM), a joint venture between Boston University and Boston Medical Center, have discovered a novel approach for engrafting engineered cells into injured lung tissue. These findings may lead to new […]
Quantifying the risk of progression could help identify persons who could benefit from early interventions (Boston)—The projected cost of caring for millions of individuals who have Alzheimer’s disease (AD) worldwide will exceed a $1 trillion in a few years. In addition to the enormous health burden, patients and their caregivers experience financial, physical and psychological […]
More research involving more intense or longer-duration interventions, conducted in racially diverse samples, is needed (Boston)—Hypertensive disorders of pregnancy such as preeclampsia and gestational hypertension occur in up to 10% of pregnancies and are associated with a three-fold increased risk of chronic hypertension and up to two-fold increased risk of cardiovascular disease when compared with […]
Researchers estimate a 66% increased long-term risk of stroke (Boston) – U.S. Black women have a disproportionately higher burden of both preeclamptic pregnancy and stroke compared with white women, but virtually all existing evidence on the association between the two medical conditions has come from studies of white women. A newly published study focuses on […]
One of the first studies to highlight intersex peoples’ perspectives on their own medical care (Boston)— Intersex people’s (people whose sex characteristics do not fit within the strict binary categorizations of male or female) healthcare has received a lot of media attention recently, particularly with the uptick in anti-transgender legislation, which often also targets this […]
Study shows how computational approaches can drive important biomedical discoveries (Boston)—Despite advances in defining the genomic characteristics of head and neck cancers, these malignancies continue to rank among the deadliest cancers with few targeted therapies available. An important challenge in designing effective treatments is intratumor heterogeneity, the presence of multiple subpopulations of cells with distinct […]
New study expands knowledge of the genetic architecture, biological pathways leading to AD (Boston)—Alzheimer disease (AD), the most common neurodegenerative disorder in the world, affects individuals of all races and ethnicities; however, most genetic research for AD has been performed on individuals of European ancestry (EA) with a limited number of large-scale genetic studies in […]
Findings may contribute to the understanding of pathophysiology and help validate novel therapies for the prevention and treatment of COVID-19 (Boston)—COVID-19, the disease resulting from SARS-CoV-2 infection, is associated with highly variable clinical outcomes that range from asymptomatic disease to death. For those with milder infections, COVID-19 can produce respiratory infection symptoms (cough, congestion, fever) […]
Findings may have broad implications for how gallbladder cancer is treated and managed around the world. (Boston)—The quality of surgery can drastically influence both short- and long-term postoperative outcomes and is a crucial consideration in studies that assess surgical outcomes. One approach for developing accurate quality measures is benchmarking, a quality-improvement process in which the […]