This Symposium is Co-Sponsored by:BUMG Office of Equity, Vitality, & Inclusion (EVI)andBMC’s Center for Health Equity |
Race & Research: Old Challenges, New Approaches
The medical research enterprise that has reliably cradled our careers and supported our livelihoods is now under appropriate and sustained scrutiny regarding the impact of racism and structural oppression in all aspects of its practice. Society is increasingly seeking answers about the role and impact that racism and structural oppression play in every facet of medical research conducted in the US. This year, the CTSI has chosen to fashion our 2021 CTSI Symposium in memory of Dr. David Seldin as a fresh opportunity for the BUMC/BMC/BU research community to ponder these questions, challenges, and the difficult decisions associated with this focus. We will discuss novel approaches to provide better designed anti-racist research. You will learn from fellow researchers who have thoughtfully and rigorously applied anti-racist principles to engage in clinical and translational medical research. Our symposium has been designed to provide a safe, opportunity for you to think deeper about these essential issues and to challenge yourself to participate with your peers and colleagues in an open, honest and non-judgmental but challenging dialogue about race and research. During our symposium, you will also learn new techniques to improve and support a fully inclusive and equitable workforce dedicated to studying the most noteworthy and impactful questions to ensure humanity’s health and well-being. This year’s event is shaping up as one of our most timely, salient, and important symposiums. We sincerely hope you can join us!
Poster Session Winners:

“Pregnancy-Related CVD Risk Management in the First Postpartum Year”

“Quantification of Corneal Collagen Cross-Linking in Keratoconus with IS-OCT”

“Impact of a Systemwide Incidental Adrenal Mass Quality Improvement Initiative”
2nd Place:
“Investigating COPD GWAS in iPSC-derived Alveolar Epithelial Cells Using CRISPRi”
Note: the links to the recordings are below.
Poster Session Abstracts & Recordings
Poster Session: Tuesday, March 16, 2021, from 3:00-5:30 pm3:00 -4:00pmRoom A: 3:00 PM: Elisabeth Fridberg (#17) – Television Effect on Children with Autism 3:15 PM: Jennifer Sikov (#26) – Engagement in ADHD Treatment by Diverse, Urban Parents 3:30 PM: Samad Amini (#15) – Remote Diagnosis of Dementia 3:45 PM: Shahabeddin Sotudian (#29) – Social Determinants of Health and Their Effects on Predicting Missed Appointment
Room B: 3:00 PM: Mara Murray Horwitz (#8) – Pregnancy-Related CVD Risk Management in the First Postpartum Year 3:15 PM: Eung-Mi Lee (#20) – Fulfilling an Unmet Need: Integrating Family Planning Services 3:30 PM: Jyoti Sonkar (#28) – E-cigarettes and Their Impact on Periodontal Health: A Systematic Review 3:45 PM: Raagini Jawa (#5) – Racial Disparities for Access to Medications for Opioid Use Disorder
Room C: 3:00 PM: Dar Heinze (#3) – Notch Activation During Mesoderm Induction Modulates Emergence of T/NK Cells 3:15 PM: Lillian Juttukonda (#6) – COVID-19 Associated With Increased Immune Cell Infiltration in the Placenta 3:30 PM: Rhiannon Werder (#14) – Investigating COPD GWAS in iPSC-derived Alveolar Epithelial Cells Using CRISPRi 3:45 PM: Divya Veerapaneni (#30) – Co-segmentation Of Glomeruli From Multiple Stains Using Deep Learning
Room D: 3:00 PM: Christopher Lin (#22) – Deep Learning Driven Assessment of Inflammatory Regions in Digitized Diopsies 3:15 PM: Maetal Haas-Kogan (#18) – Mississippi CHAMPS: Decreasing Racial Disparities in Breastfeeding 3:30 PM: Soyoung Lee (#24) – Mechanical Temporal Summation is Associated with Greater Muscle Co-contraction During Walking in Knee Osteoarthritis 3:45 PM: Eugene Hsu (#4) – Quantification of Corneal Collagen Cross-Linking in Keratoconus with IS-OCT
4:30 – 5:30pmRoom A: 4:30 PM: Grace Ferri (#2)- Novel Cocrystallization of Apolipoprotein A-I with Butyric Acid 4:45 PM: Daniel Leslie (#21) – Soft Robotic Antiretropulsion Device 5:00 PM: Andrey Vyshedskiy (#31) – Novel Prefrontal Synthesis Intervention Improves Language in Children with Autism 5:15 PM: Lisa Quintiliani (#11)- Narrative Review of Smoking Cessation Interventions for People with HIV in China
Room B: 4:30 PM: Joshua Singh (#27) – Miniaturization and Multiplexing of Lipid Sample Preparation for GC-MS Analysis 4:45 PM: Sonja Kytomaa (#7) – Atherosclerosis, Coronary Heart Disease Risk, and Cognitive Impairment 5:00 PM: Lauren Barber (#1) – Predicted Vitamin D Status and Colorectal Cancer Incidence in Black Women 5:15 PM: Sehar Resad (#12) – Evaluation of Total Hip Arthroplasty Component Position with TraumaCad
Room C: 4:30 PM: Soyoung Lee (#25) – Association of Pain Intensity and Patterns with Response to Exercise in Knee Osteoarthritis 4:45 PM: Enzo Plaitano (#10) – Simulation-Based Mass Gathering Medicine Training for Prehospital Providers 5:00 PM: Alison Pease (#23) – Impact of a Systemwide Incidental Adrenal Mass Quality Improvement Initiative
9th Annual Translational Research Symposium Poster Abstracts. |
Symposium Speaker Presentation Recordings
Keynote Speaker & Speakers Bios
Leonard E. Egede, MD, MS
Director, Center for Advancing Population Science; Professor of Medicine & Eminent Scholar; Chief, Division of General Internal Medicine; Associate Director, Diversity, Genomic Sciences, and Precision Medicine Center; Co-Director, MCW CTSI KL2 Program; Director, MCW CTSI Master’s in Clinical/Translational Research
Dr. Leonard Egede is a general internist and health services research, tenured Professor of Medicine, Eminent Scholar, and Chief of the Division of General Internal Medicine at the Medical College of Wisconsin. He is also the Director of the Center for Advancing Population Science, Associate Director of Diversity in the Genomic Sciences and Precision Medicine Center, Director of the CTSI KL2 Program, and Director of the CTSI Master’s in Clinical/Translational Research. As a nationally recognized health disparities researcher, Dr. Egede’s research has focused on developing and testing innovative interventions to reduce and/or eliminate health disparities related to race/ethnicity, socioeconomic status, and geographic location for chronic medical and mental health conditions. His career started with diabetes as a template disease, but he has since worked with other physical and mental illnesses. Dr. Egede is currently PI of 3 NIH R01s, the MCW NCATS KL2 Program, and an NIH R21. Dr. Egede has published over 300 manuscripts documenting the existence of disparities and showing that factors at the personal, provider and system-level have an influence on health outcomes. His work has led to the recognition that disparities exist and moved the field towards focusing on what can be done to address inequities.
David M. Center, MD
Dr. Center is the Gordon and Ruth Snider Professor of Pulmonary Medicine, Associate Provost for Translational Research, and Director of the BU Clinical and Translational Science Institute. For 31 years, he has been the Chief of the Pulmonary, Allergy, Sleep, and Critical Care Division having added Allergy and Sleeps accreditation to the program during his tenure. In that position, he supervises 50 MD and PhD clinical and research faculty and 18 post-doctoral fellows in 3 major research areas (Outcomes Medicine and Informatics, Developmental Biology and, Regenerative Medicine, and Lung Inflammation and Immunity. He is a co-discoverer of Interleukin-16 which is the topic of BU-owned intellectual property licensed by multiple bioscience companies. He has been the PI of R01, P50, P01, UL, U54, U19, and T32 grants and the mentor for 8 K08s. The Biology of the Lung T32 is the largest at BU responsible for training over 250 pulmonary, allergy, and critical care MD and PhD fellows and PhD students including multiple Chairs of Medicine, Deans, and Chiefs of Pulmonary in both medicine and pediatrics. He is the Director of the Boston University Clinical and Translational Science Institute since its inception in 2008 and the PI of its NCATS sponsored Clinical and Translational Science Award. During this tenure, he has instituted a number of innovative changes to the BU research environment, including the only institutional TL program in regenerative medicine in the CTSA network of 64 Universities.
Christopher W. Shanahan, MD, MPH, FACP
Christopher W. Shanahan, MD, MPH, FACP is a General internist with a focus in Primary Care Internal Medicine and Addiction. He is Board Certified in both Internal Medicine and Addiction Medicine. He is the Faculty Lead for Research Networking for Boston University’s Clinical Translational Sciences Institute (CTSI) and serves on its Senior Executive Committee and its Clinical Informatics unit. His research focus includes: chronic pain management, substance use disorders, community-based research networks, and research informatics and application development to improve medical care quality and eliminate health disparities in underserved urban populations.
Megan Bair-Merritt, MD, MSCE
Dr. Bair-Merritt is a Professor of Pediatrics. She is a general pediatrician and child health services researcher who has conducted social epidemiology and intervention research in the area of family violence for over 10 years. She has published 87 scientific and/or invited articles, 13 letters/editorials, and 10 book chapters that predominantly focus on family violence and child health. She has received three R01-level awards as PI (and 3 additional awards as Co-I) from the National Institute of Justice and the Maternal and Child Health Bureau (federal funding for violence research generally comes from non-NIH institutes), an AHRQ T32 training grant, and multiple large foundation grants. She serves as the Executive Director of Pediatrics’ Center for the Urban Child and Healthy Family, multi-PI of Boston University’s CTSI, and as Chair of Women’s Leadership through the Boston University Medical Group’s Office of Equity, Vitality and Inclusion. Her scholarly work has moved forward the field’s understanding of how intimate partner violence (IPV) affects children, influenced how IPV screening and related interventions are implemented in the medical setting and shaped conceptualizations of relationships with teen dating violence. Her publications have been cited in critical policy pieces and clinical guidelines including the Institute of Medicine’s consensus report Clinical Preventive Services for Women: Closing the Gaps, the World Health Organization’s Guidelines for Prevention and Clinical Intervention for Female Survivors of Intimate Partner Violence, the United States Preventive Services Task Force’s recommendation for Intimate Partner Violence and Abuse of Elderly and Vulnerable Adults: Screening, as well as the American Academy of Pediatrics guidelines on IPV screening in the pediatric setting. She recently was invited to present about IPV homicide at the National Academy of Science, Engineering and Medicine’s Workshop on Firearm Injuries and Death.
Michael K. Paasche-Orlow, MD, MA, MPH
Professor of Medicine, General Internal Medicine, Boston University School of Medicine, Boston Medical Center.
As a primary care clinician and a nationally recognized expert in the field of health literacy, I have dedicated my career to improving the care of vulnerable populations. I am currently a co-investigator with six clinical studies that examine health literacy and doctor-patient communication, various modes of patient education, and empowerment. I have been the lead designer of nine patient-oriented interactive behavioral informatics programs and have helped create and evaluate a range of patient empowerment and decision support tools. With over 200 peer-reviewed papers, my work has brought attention to the role that health literacy plays in racial and ethnic disparities, improving informed consent, and improving advanced care planning, as well as to the fact that appropriately designed information technologies can be empowering for patients with low health literacy.
Dr. Martinez is an associate professor, department chair in the Macro Department, and a research affiliate with the Center for Innovation in Social Work and Health at the Boston University School of Social Work. Her research is focused on how assets can be recognized and leveraged by communities to improve living environments and health. Dr. Sprague Martinez has expertise in urban health; community, student, and youth engaged research; photovoice; community assessment and mobilization; and qualitative research methods and analyses.
Madina Agénor, SCD, MPH
Dr. Agénor is the inaugural Gerald R. Gill Assistant Professor of Race, Culture, and Society in the Department of Community Health at Tufts University. She is also Adjunct Faculty in the Department of Obstetrics and Gynecology at Tufts University School of Medicine and The Fenway Institute at Fenway Health. A social epidemiologist by training, Dr. Agénor investigates sexual and reproductive health and cancer screening and prevention inequities in relation to sexual orientation and heterosexism, race/ethnicity and racism, and gender identity and gender-related discrimination using a multilevel, intersectional lens. Specifically, she conducts quantitative, qualitative, and mixed-methods research to elucidate the structural and social determinants of HIV and STI prevention and testing, HPV vaccination, cervical cancer screening, and contraceptive care among marginalized U.S. populations, especially lesbian, bisexual, and queer women and girls, transgender and gender diverse young adults, and Black lesbian, gay, bisexual, transgender, and queer (LGBTQ) people. Prior to joining the Tufts faculty, Dr. Agénor was Assistant Professor of Social and Behavioral Sciences at Harvard T.H. Chan School of Public Health and a Postdoctoral Research Fellow in the Harvard Educational Program in Cancer Prevention. She holds a Doctor of Science (ScD) in Social and Behavioral Sciences with a concentration in Women, Gender, and Health from Harvard T.H. Chan School of Public Health and a Master of Public Health (MPH) in Sociomedical Sciences from Columbia University Mailman School of Public Health.
John P.A. Ioannidis, MD, DSc
Dr. Ioannidis is Professor of Medicine, Professor of Epidemiology and Population Health, and Professor (by courtesy) of Biomedical Data Science at the School of Medicine, Professor (by courtesy) of Statistics at the School of Humanities and Sciences, and co-Director of the Meta-Research Innovation Center at Stanford (METRICS). He is the recipient of many awards and he has been elected as Einstein fellow at the Berlin Institute of Health. He has been inducted in the Association of American Physicians, the European Academy of Cancer Sciences, the American Epidemiological Society, the European Academy of Sciences and Arts, and the US National Academy of Medicine. He has received honorary titles from FORTH and U Ioannina, honorary doctorates from U Rotterdam, U Athens, and U Tilburg and multiple honorary lectureships. He is among the 10 scientists with the highest current citation rate in the world (>5,000 new citations per month per Google Scholar).
Vasan Ramachandran, MD, FACC, FAHA
I am a cardiologist with subspecialty training in echocardiography and cardiovascular epidemiology and have a long-standing commitment to clinical epidemiological research. I am Chief in the Section of Preventive Medicine and Epidemiology in the Department of Medicine and Professor of Medicine and Epidemiology at Boston University Schools of Medicine (BUSM) and Public Health (BUSPH). I am the Principal Investigator of the Framingham Heart Study (FHS, the oldest running epidemiology study in the US) and the Risk Underlying Rural Areas Longitudinal (RURAL) Study (one of the youngest cohort studies in the US). I also direct the FHS echocardiography-vascular imaging laboratory. I have been an Associate Editor for Circulation, the flagship journal of the American Heart Association, from 2002-2016, and I was the founding editor-in-chief for its daughter journal, Circulation Cardiovascular Genetics from 2008-2018. I am a trained mentor and serve as the PI of a Post-doc T32 program in ‘Interdisciplinary Training in Cardiovascular Epidemiology’ and the PI of BU’s R38 program (Stimulating Access to Research in residency) focused on training medical residents in research.
My own research is focused on: A) The epidemiology and novel risk markers of heart failure (HF), with a focus on HFpEF, including evaluating the role of LV and vascular remodeling and ventricular-vascular coupling; B) Population-based echocardiography and arterial stiffness, including identifying biological, environmental, and genetic determinants, normative standards and prognostic implications; C) Population-based exercise testing, with a current focus on cardiopulmonary exercise testing with metabolite profiling; D) Detailed assessment of novel biomarkers of CVD risk, risk prediction, subclinical atherosclerosis and genomics of CVD traits, including metabolomics, proteomics, and the microbiome.
Renee D. Boynton-Jarrett, MD, ScD
Dr. Boynton-Jarrett is a pediatrician and social epidemiologist is an associate professor at Boston Medical Center and Boston University School of Medicine. She is the founding director of Vital Village Networks. Vital Village uses a trauma-informed lens to improve community capacity to promote child wellbeing and advance equity through dedicated collaborative partnerships, research, data-sharing, and community leadership development in Boston and nationally through the NOW Forum and CRADLE Lab. Her scholarship has focused on early-life adversities as life course social determinants of health. She has a specific concentration on psychosocial stress and neuroendocrine and reproductive health outcomes, including obesity, puberty, and fertility. She is nationally recognized for work on the intersection of community violence, intimate partner violence, and child abuse and neglect, and neighborhood characteristics that influence these patterns. She has received numerous awards for teaching, clinical care, and public health including the Massachusetts Public Health Association Paul Revere Award for outstanding impact on public health. She received her AB from Princeton University, her MD from Yale School of Medicine, and ScD in Social Epidemiology from Harvard School of Public Health, and completed a residency in Pediatrics at Johns Hopkins Hospital.
William Adams, MD
Dr. William Adams is an epidemiologist, medical informatician, and practicing pediatrician at Boston Medical Center (BMC). He is Professor of Pediatrics, BU-CTSI Director of the Biomedical Informatics Core (BU-BIC), and Director of Community Health Informatics for the Boston HealthNet. His research focuses on developing and evaluating information technology (IT)-based solutions for improving health and the quality of healthcare for urban populations, particularly children, and includes EHR-based technologies, patient-centered IT, immunization decision support, predictive analytics, clinical data warehousing, and research data networking.
Thea James, MD
Dr. James is Vice President of Mission and Associate Chief Medical Officer at Boston Medical Center. She is an Associate Professor of Emergency Medicine and Director of the Violence Intervention Advocacy Program at BMC. Dr. James is a founding member of the National Network of Hospital-Based Violence Intervention Advocacy Programs (NNHVIP). In 2011 she was appointed to Attorney General Eric Holder’s National Task Force on Children Exposed to Violence.
As Vice President of Mission Dr. James works with caregivers throughout BMC. Additionally, she has primary responsibility for coordinating and maximizing BMC’s relationships and strategic alliances with a wide range of local, state, and national organizations including community agencies, housing advocates, and others that partner with BMC to meet the full spectrum of patients needs. The goal is to foster innovative and effective new models of care that are essential for patients and communities to thrive. Integrating upstream interventions into BMC’s clinical care models are critical to achieving equity and health in the broadest sense.
Dr. James served on the Massachusetts Board of Registration in Medicine 2009-2012, where she served as chair of the Licensing Committee. She is 2008 awardee of Boston Public Health Commission’s Mulligan Award for public service, and a 2012 recipient of the Suffolk County District Attorney’s Role Model Award. She received The Boston Business Journal Healthcare Hero award in 2012 &2015. She was 2014 recipient of the Schwartz Center Compassionate Care Award. The Boston Chamber of commerce awarded Dr. James with the Pinnacle Award in 2015, which honors women in business and the professions. She was a 2019 Massachusetts Public Health Association Health Equity Champion. In 2020 Dr. James received the American College of Emergency Medicine Lifetime Achievement Award. Also, in 2020, The History Project presented her with a History Maker Award. Dr. James recently received the inaugural 2020 Thea James Social Emergency Medicine Award from the American College of Emergency Physicians.
Dr. James’ passion is in Public Health both domestically and globally. For many years she and colleagues partnered with local partners in Haiti, and Africa, to conduct sustainable projects. She is a member of the Board of Directors of Equal Health. Equal Health works with local partners in Haiti to create strong, sustainable medical and nursing education systems.
Dr. James served as a Supervising Medical Officer on the Boston Disaster Medical Assistance Team (MA-1 DMAT), under the Department of Health and Human Services. She has deployed to post 9/11 in NYC, Hurricane Katrina in New Orleans in 2005, Bam, Iran after the 2003 earthquake, and Port-Au-Prince Haiti after the earthquake of 2010. Dr. James traveled to Haiti with MA-1 DMAT one day after the 2010 earthquake.
A graduate of Georgetown University School of Medicine, James trained in Emergency Medicine at Boston City Hospital, where she was a chief resident.
Elena Mendez-Escobar, PhD, MBA
Executive Director, Growth and Innovation
Boston Medical Center Health System
Elena’s passion is to right inequities and improves healthcare for underserved and high-needs populations. As a former Associate Partner at McKinsey, she helped states, payers, and other organizations serving Medicaid, rethink strategy and transform operations. She is a co-founder of McKinsey’s Center for Societal Benefit through Healthcare, focused on underinvested areas of healthcare such as mental health, addiction, or social determinants of health.
Cassandra M. Pierre, MD, MPH, MSc
Dr. Pierre is an Assistant Professor at the Boston University School of Medicine; she serves as the Medical Director of Public Health Programs and the acting Hospital Epidemiologist at Boston Medical Center; and as the Chair of the Diversity and Inclusion Council for the Boston University Medical Group. Her focus is on population and public health in communities struggling with racial, economic and social marginalization. Dr. Pierre’s research is focused on infection prevention in vulnerable populations. Her clinical interests include HIV management in special subpopulations (including immigrants of color and pregnant women). During the COVID-19 pandemic, she has led Boston Medical Center’s multidisciplinary Infection Prevention and PPE response, designed ambulatory and operative re-opening protocols and advised Occupational Health and department leadership on COVID-19 prevention in healthcare workers. Dr. Pierre has also collaborated with local community organizations to develop and implement strategies to reduce COVID-19 infection in communities of color).
Yvette C Cozier, DSc
Dr. Yvette Cozier is an Associate Professor of Epidemiology, and the Assistant Dean of Diversity and Inclusion at Boston University School of Public Health, and a Senior Epidemiologist at the Slone Epidemiology Center at Boston University School of Medicine. Dr. Cozier’s research is focused on the influence of psychosocial factors including experiences of racism and neighborhood segregation in the development of chronic illness in women of color. She is a long-term investigator on the Black Women’s Health Study (BWHS), and the co-principal investigator of the Epi AWARE Study of Asian American women, a collaboration between BU Schools of Public Health and Social Work.
David C. Henderson, MD, currently serves as Psychiatrist-in-Chief, Division of Psychiatry, at Boston Medical Center and Professor and Chair, Department of Psychiatry, at Boston University School of Medicine. Dr. Henderson previously served as Director of The Chester M. Pierce, MD Division of Global Psychiatry at Massachusetts General Hospital (MGH), Director of the MGH Schizophrenia Clinical and Research Program, and Medical Director of the Harvard Program in Refugee Trauma. Dr. Henderson serves as Co-Director of the NIMH T32 MGH-BUSM Global Mental Health Clinical Research Fellowship. He has worked internationally for the past 21 years in resource-limited settings and areas impacted by mass violence, disasters, and complex emergencies. Dr. Henderson has conducted research and training programs in Bosnia, Cambodia, East Timor, Ethiopia, Haiti, Liberia, New Orleans, New York City, Rwanda and Peru, South Africa, and Somaliland among other places. His work has consisted of field studies, needs assessments, mental health policy development, and strategic planning, quantitative and qualitative surveys, mental health capacity building programs for specialized and primary health professionals, and skill-transfer program evaluation. In the United States, he has conducted more than 30 randomized clinical trials in severely mentally ill populations. Dr. Henderson has also directed a schizophrenia research training fellowship and mentored trainees and junior faculty who have progressed to K awards and secured other independent funding. He actively mentors 10 psychiatry residents and 4 postdoctoral fellows on data-driven international research projects
Symposium Speaker Presentation Slides
Agenda
Register for the 9th Annual CTSI Symposium
List of Registrants
In Memory of David Seldin, MD, PhD (1957-2015)
The Annual Translational Science Symposium, sponsored by the BU CTSI and spearheaded by Dr. David Seldin, MD, PhD, began in 2010 as a half-day event with a keynote speaker, success stories, poster session, and discussion groups. Over the years, this symposium has expanded into a full-day event and stayed true to its roots, with themes of relevant translational science topics, such as disparities in healthcare and data science. Its informative talks, robust discussion sessions, and intriguing posters from across the BU Campus make it a special day, one during which we honor Dr. Seldin.
Dr. Seldin was a founding member of the BU CTSI in 2008. He made critical contributions to our Core facilities program, instituting a highly innovative core voucher system to subsidize usage. He is remembered with an appreciation for organizing the Annual Translational Science Symposium. Each part of the event bears his signature, including the idea itself, the types of speakers, poster sessions, and venues. We are deeply indebted to him for his vision and his wisdom. We want these annual symposia to convey a sense of his sincere love of science. We hope future events will be enjoyed, as he always wanted everyone to have fun!
Dr. David Seldin was a Professor of Medicine and Microbiology at Boston University School of Medicine. He became Director of the Amyloidosis Center in 2007 and Chief of the Section of Hematology-Oncology in 2008. His research interests were cancer and blood disorders, particularly light chain (AL) amyloidosis.