Dr. Erdjan Salih Authors Chapter in Springer Protocols Oral Biology Book
Dr. Erdjan Salih, Associate Professor in the Department of Periodontology at the Henry M. Goldman School of Dental Medicine, recently published a chapter in the Springer Protocols book 2nd Edition, Oral Biology: Molecular Techniques and Applications. The chapter is entitled “Qualitative and Quantitative Proteome Analysis of Oral Fluids in Health and Periodontal Disease by Mass Spectrometry.”
Dr. Salih’s chapter provides a detailed guide to experiments using multidimensional protein separation and mass spectrometry on oral fluids. It elaborates on specific pre-analytical steps for oral fluids in combination with stable-isotope chemistries to enable reliable, quantitative mass spectrometry analysis. Mass spectrometry can aid with protein identification and characterization, and hence yield important advances in work with oral fluids such as saliva and gingival crevicular fluid (GCF). Saliva and GCF can serve as sources of diagnostic biomarkers for both systemic and local oral cavity health status and their protein compositions have been studied using mass spectrometry.
“It was an honor to be invited to write this chapter involving state-of-the-art technologies in a book that coalesced a series of chapters written by global experts in oral biology from 13 countries,” said Dr. Salih about the publication.
Dr. Salih has done extensive work with biomedical models, including ex-vivo cancer-bone metastasis model systems using mouse bone organ cultures to evaluate the effects of clinically-used bisphosphonates on cancer-bone interactions. His research in these special areas most recently led to an invitation to write another major book chapter in the Springer Protocols 3rd Edition, Bone Research: Methods & Protocols. The chapter is entitled “Ex-Vivo Cancer-Bone Cell Interaction Model Systems” scheduled to be published at the end of 2017.
The Springer Protocols are a database of reproducible laboratory protocols in life sciences and biomedicine that have been comprehensive and detailed experimental approaches for the past 30 years. They have an online subscription-based database as well as a book series with over 1,000 volumes. All protocols are written and reviewed by experts in their specific subject areas.
For more information about Oral Biology: Molecular Techniques and Applications, please visit: http://link.springer.com/book/10.1007/978-1-4939-6685-1.