New Molecular Test for Malaria Paper Online!

Online article! Work with our partners describes a new way to mine the malaria genome to create primer sets that are 100x more sensitive at detecting malaria when compared to Pf18S rRNA primers. The new assay was validated with human samples.

Srinivasa Raju, L., Kamath, S., Chandana Shetty, M., Satpathi, S., Mohanty, A. K., Ghosh, S. K., Kolluri, N, Cabodi, M., Klapperich, C. Padmanaban, G. and Nagaraj, V. A. (2019), “Genome Mining–Based Identification of Identical Multi-Repeat Sequences (IMRS) in Plasmodium falciparum Genome for Highly Sensitive qPCR Assay and its Application in Malaria Diagnosis.” The Journal of Molecular Diagnostics. https://doi.org/10.1016/j.jmoldx.2019.04.004

The work was a collaboration with Jigsaw Bio Solutions, Bangalore, Karnataka, India, the Institute of Life Sciences, Bhubaneswar, Odisha, India and the Department of Biochemistry, Indian Institute of Science, Bangalore, India.