Hadi Nia Published in PNAS Nexus April Issue
This April, Center faculty members Hadi Nia published “Alteration of mechanical stresses in the murine brain by age and hemorrhagic stroke” in the PNAS Nexus journal. Their research works towards a better understanding of residual mechanical stresses in the brain.
Also known as solid stresses, mechanical stresses develop when brain tissues grow rapidly, such as during development or tumor growth. These mechanical stresses are linked to aging and certain neurological disorders, but their causes are poorly understood. Namely, Nia’s team were interested in understanding the causes of solid stresses and why they persist after growth has stopped.
The team studied the spatiotemporal distribution of residual solid stresses in mice brains to shed light on the biological and immunological consequences of solid stresses. Namely, the team found that such stresses could be used as biomarkers for aging, meaning measuring solid stress levels could help diagnose and monitor neurological conditions.