Three-year Renewals

After three years, the application must be resubmitted and reviewed by the committee.

1. For all expiring IBC Protocols, complete a Three-Year Resubmission in RIMS and click “confirm the submission” to send it to the IBC Office for review.
2. Make sure the PI and all lab staff complete the annual EHS Lab Safety Training requirement , the annual Research Occupational Health Program (ROHP) clearance update (contact ROHP at ; 617-414-7647), and any other applicable training requirements.
3. The IBC Office will notify you when your Three Year Resubmission has been processed and approved.

De novo IBC Approval is required for the continuation of the work beyond the previous protocol expiration date.

1. Log in to RIMS.
2. Under Activities and Authorizations in the left menu, click on Biological Use Authorization – IBC Application.
3. Click on the blue-underlined Project Title of your IBC Protocol due for three-year resubmission.
4. In the left menu, click the blue links in sequence up to the Grant Funding Information page.
5. Check the radio button for Three-Year Resubmission.
   • Note: Make sure any old amendments listed in the amendment summary box are deleted, as the entire project should be described in completion and is subject to de novo review.
6. On the bottom of the Grant Funding Information page, click Save Changes.
7. Click to the Dual Use Research of Concern page to review the questions and confirm your answers. If you make any changes, click on Save Changes at the bottom of the page.
8. Click on all other pages to review the questions and confirm your answers. Update any of these application pages/sections with the relevant information regarding your IBC protocol, describing procedures as if you were seeking the original IBC approval.
9. After all updates are complete and saved, select Confirm the Submission to send the Three-Year Resubmission to the IBC Office.

On the Personnel page, delete and add personnel as appropriate.

To delete a person

1. Select that person by clicking the “+” next to their name in the table at the top of the page.
2. Click the “Delete” button at the bottom of the page to remove them from the protocol.

To add a person

1. Click the “Add Personnel” button at the bottom of the page.
2. Complete questions on training and experience.
3. If a person has been entered into the PI Profile when you first log in to RIMS (highly recommended), you may click the “Select personnel from your PI list” button to add that person.

On the Research Laboratory Facility Information page, delete and add research spaces as appropriate, including all facilities used for the project.

To delete a location

1. Select the location by clicking the “+” next to its name in the table at the top of the page.
2. Click the “Delete” button at the bottom of the page to remove it from the protocol.

To add a location

1. Click the “Add Research Laboratory Location” at the bottom of the page.
2. Complete all subsequent questions.
3. Be sure to update the Biological Safety Cabinet information/certification on the Personal Protective Equipment/Safety Equipment page, if applicable.

On the Research Project Description page:

• Review the details of your experiments, with special focus on the second question (regarding lab procedures).
• Make sure this reflects a complete description of your biohazardous and recombinant DNA work.
• Make any other edits or changes within your project description, as appropriate.

Update changes in…

• Biohazardous agents on the Hazardous Biological Agent page
• rDNA host-vector-donor components on the Recombinant DNA page
• Human and NHP materials on the Potentially Infectious Material page
• Details of any other changes should be updated on the other relevant pages