All research laboratories possessing any Class 3b and/or Class 4 laser systems not contained within a confocal, flow cytometer or other class 1, 2 or 3a interlocked enclosure, whether active or inactive, must be permitted through the DMPRS. To initiate the permitting process, an application for “Class 3b and Class 4 Laser Use Permit (Non-Human Use)” must be submitted to the DMPRS. The application must include locations of use, complete inventory, approved personnel list, Standard Operating Procedures (SOPs), and necessary safety requirements for all Class 3b and Class 4 lasers.
Upon receipt of the “Class 3b and Class 4 Laser Use Permit (Non-Human Use)”, the DMPRS will conduct a laser safety inspection. After review of all pertinent information, the application will be acted upon by the LSS. All permits shall be renewed biennially.
The Permit Holder shall submit a “Permit Amendment” if changes in location of use, laser inventory, personnel, or Standard Operating Procedures (SOPs) occur.
Laser Procurement
Researchers who intend to purchase any laser systems that are classified as, or otherwise contain, a Class 3b or Class 4 laser must request pre-approval from the LSO prior to purchase. Following pre-approval, permitted laboratories may place orders through the purchasing liaison in their department or center.
Laser Inventory and Registration
The following classes of lasers are required to be inventoried with the DMPRS and will be registered with the state Massachusetts (MA DPH):
Class 3b lasers
Class 4 lasers
Note:This does not include embedded 3b or 4 laser systems. When the embedded system is disabled and the interlocks are open, it should be treated with its appropriate laser classification.
Be included as an authorized user on a current Laser Permit.
With a valid Kerberos password, individuals can complete the Laser Safety Online Training module at any time. This training is available online through the SciShield Course Directory. A record of trainings and permits will be maintained by DMPRS. For any additional laser safety trainings, contact DMPRS.
Standard Operating Procedure (SOPs)
SOPs are required for the safe operation of laser systems. The Permit Holder utilizing a Class 3b or Class 4 laser system must submit an SOP for each laser system. Procedures shall address system alignment and accurately describe the research, potential hazards, and methods to operate the laser system.
SOP review or modification should occur:
Prior to all new experimental uses of an existing laser system;
Prior to PPE modifications;
Prior to room layout modifications;
Following inventory or associated personnel changes;
Prior to modifying beam alignments;
Biennially; and
Following all incidents and near misses regarding exposure of personnel or property to laser emissions.
Please refer to appendix BU-03 (Alignment Guidance) for helpful safety guidelines.
Research with Human Subjects
The use of lasers for research with human subjects requires both an active Laser Use Permit and a protocol approved by the Institutional Review Board. The protocol shall be reviewed by the Laser Safety Officer or designee to ensure subject safety. All laser exposure must be demonstrated by measurement or calculation to be below the laser’s Maximum Permissible Exposure (MPE) as specified in ANSI Z136.1.