News
BWHS Researchers develop breast cancer prediction tool for Black women
Black women are more likely to develop breast cancer at earlier ages and with worse outcomes than white women. Researchers at Boston University have now developed a risk prediction model for breast cancer in Black women, suitable for use in a health care setting. Breast cancer risk prediction tools are used by clinicians to identify women at higher than average risk of breast cancer for early or more frequent screening by mammography and other modalities, and this new model is an easy way for primary care providers to guide screening recommendations or referral for genetic testing, particularly for young Black women.
Read more about this new risk prediction model here: Medical Xpress - Researchers develop breast cancer prediction tool for Black women
Watch an interview with the BWHS's Dr. Julie Palmer: MSN - Researchers develop breast cancer prediction tool for Black women
Palmer JR, Zirpoli G, Bertrand KA, Battaglia T, Bernstein L, Ambrosone CB, Bandera EV, Troester MA, Rosenberg L, Pfeiffer RM, Trinquart L. A validated risk prediction model for breast cancer in U.S. Black women. J Clin Oncol 2021. doi: 10.1200/JCO.21.01236 (epub ahead of print).
Vitamin D status and colon cancer risk in the BWHS
Prior research has shown that Vitamin D levels are generally lower in Black populations; now BWHS research suggests that low vitamin D levels may contribute to the higher rate of colorectal cancer among Black women.
Read more about this important research on BlackDoctor.org
Barber LE, Bertrand KA, Petrick JL, Gerlovin H, White LF, Adams-Campbell LL, Rosenberg L, Roy HK, Palmer JR. Predicted vitamin D status and colorectal cancer incidence in the Black Women's Health Study. Cancer Epidemiol Biomarkers Prev 2021. doi: 10.1158/1055-9965.EPI-21-0675 (epub ahead of print).
African-American and white women share genes that increase breast cancer risk
The same genes that greatly increase the risk of breast cancer in U.S. white women, including women of Ashkenazi Jewish descent, also greatly increase breast cancer risk among African American women. These genes include the BRCA1, BRCA2 and PALB2 genes, each of which was associated with a more than seven-fold risk of breast cancer, as well as four other genes associated with a more moderate increase in risk. Previous studies of women of African ancestry were too small to assess genes other than BRCA1 and BRCA2.
Moderate drinking lessens risk for lupus among black women
Among black women, consuming four or more alcoholic drinks per week is associated with a significant decrease in the risk for systemic lupus erythematosus, while cigarette smoking was linked to a nonsignificant increase in the risk for the disease, according to data published in Arthritis Care & Research.
Read more at Healio
Studies examine trends in pain medication use
A new study reveals that acetaminophen use and over-dosing rise in cold/flu season in the United States, primarily due to increased use of over-the-counter combination medications treating upper respiratory symptoms. Another study reports that acetaminophen is the most commonly used analgesic in France, with more high-dose tablets being consumed in recent years. The findings, which are published in the British Journal of Clinical Pharmacology, indicate that individuals should take special care to follow labeled dosing directions for acetaminophen-containing products.
Nearly one out of five NSAID users exceed daily limit
Chances are you or someone you know has used nonsteroidal anti-inflammatory drugs (NSAIDs) within the last month. NSAIDs, such as Advil (ibuprofen), Aleve (naproxen) and Celebrex, are among the most commonly used medicines in the US. Now, for the first time, researchers have found that 15 percent of adult ibuprofen users exceed the maximum recommended dose of ibuprofen or other NSAIDs in a one-week period.
Researcher studying ways to reduce health disparities for Black women dealing with insomnia
Black women are among those most likely to have insomnia, according to Lynn Rosenberg, ScD, associate director of Boston University’s Slone Epidemiology Center and a principal investigator of the Black Women’s Health Study (BWHS). Rosenberg has been awarded a three-year $2,225,495 grant from the Patient-Centered Outcomes Research Institute (PCORI) to study this. The study will be using a self-administered internet program called SHUTi (Sleep Healthy Using the Internet), a web-tool based on cognitive behavioral therapy (CBT).
African-American women with type 2 diabetes may have higher risk for ER-neg breast cancer
Among African-American women, those with type 2 diabetes may have a higher risk of developing estrogen receptor (ER)-negative breast cancer.
Tdap vaccinations in pregnant women increase by 50%
The rate of pregnant women receiving a tetanus, diphtheria and pertussis vaccine jumped dramatically in numerous metropolitan areas of the United States — by more than 50% over several years — according to the CDC. The increase in immunization stems from recommendations from the Advisory Committee on Immunization Practices, researchers said.
Dr. Julie Palmer awarded AACR Distinguished Lecture on the Science of Cancer Health Disparities, funded by Susan G. Komen®
This award honors an investigator whose novel and significant work has had or may have a far-reaching impact on the etiology, detection, diagnosis, treatment or prevention of cancer health disparities.