L. Adrienne Cupples Award Presentation - Biomarker-Driven Trial Designs: Mitigating Measurement Error in Time-to-Event Outcomes for Better Treatment Outcomes.

This year’s recipient of the L. Adrienne Cupples Award for Excellence in Teaching, Research, and Service in Biostatistics, Dr. Susan Halabi, PhD, will present on: Biomarker-Driven Trial Designs, specifically Mitigating Measurement Error in Time-to-Event Outcomes for Better Treatment Outcomes. Dr. Susan Halabi, PhD, is the James B. Duke Distinguished Professor of Biostatistics and Bioinformatics and Chief of the Division of Biostatistics in the Department of Biostatistics and Bioinformatics at Duke University Medical Center. For over twenty-five years, she has been at the forefront of designing and analyzing clinical trials in oncology. She develops novel methods for the design and analysis of clinical studies and innovative variable selection methods for biomarkers and high-dimensional data. Dr. Halabi is committed to ensuring statistical rigor in all her clinical studies so that they are impactful to patients and society. Her most significant contributions concern building and validating prognostic models of outcomes for prostate cancer and identifying surrogate endpoints for overall survival. She has served as the Principal Investigator (PI) on several federally funded grants and continues to lead multiple federally supported research projects. Dr. Halabi has over 300 peer-reviewed publications and has co-edited two books that have become key works in the field: Oncology Clinical Trials (2nd Edition, Demos 2018) and Textbook of Clinical Trials in Oncology (CRC Press 2019). A past president of the Society for Clinical Trials, she has received numerous awards, including being named a Fellow of the Society for Clinical Trials, the American Statistical Association, and the American Society for Clinical Oncology.