Profiles

Gheorghe Doros, PhD

Professor, Biostatistics - Boston University School of Public Health

617-358-2494
doros@bu.edu
Crosstown Center - 331
View Full Profile at BUMC

Biography

Gheorghe Doros is Professor of Biostatistics and director of the Biostatistics Consulting Group. He received his PhD in Statistics from Yale University and joined BUSPH’s Department of Biostatistics in 2006 after spending two years at Eli Lilly, as a member of that company's Drug Discovery and Toxicology department. Dr. Doros’s research on methodological approaches and strategies has been concentrated in the area of clinical trials, more specifically on Bayesian approaches to clinical trials and the area of placebo response in clinical trials. The outcome of his work has been a corner stone in developing a host of collaborations with outstanding faculty, clinicians, and researchers at the Boston University Medical Campus and at other institutions. These productive collaborations have resulted in several federally funded grants. Dr. Doros authored and co-authored many peer-reviewed publications of original and innovative research which has had a major impact on the field. On the majority of publications, Dr. Doros is the lead statistician author. He demonstrated continuing record of multidisciplinary research that has had a major impact on the rapidly changing field. His publications on clinical trials; most proposing the design, analysis and new methodologies or of significant contributions to this field.

Dr. Doros is a very active and effective teacher and mentor in the department of Biostatistics. His teaching philosophy is to pursue an active approach to learning and to engage students to think critically. He taught core and elective courses for Master and PhD-level courses. The excellent course evaluations he received attests to his ability in engaging students in active learning. Dr. Doros has been awarded the excellence in teaching three times in three years.

On a national level, Dr. Doros has served as an Associate Editor for the BioMed Central’s journal Trials and as a reviewer for a number of academic journals. He served as a member of the merit review subcommittee for Epidemiology of the Department of Veteran Affairs and a member NHLBI-Ancillary Studies in Clinical Trials between 2012 and 2014. He has served as a statistical expert on a number of Independent Data Monitoring Committee(IDMC) for clinical trials and clinical programs. He served or seves as a senior consultant on multicenter trials and/or programs for the following organizations Pfizer, Takeda, Avanir, Sarepta and Children's Hospital.

Other Positions

  • Member, BU-BMC Cancer Center - Boston University
  • - Boston Medical Center

Education

  • Yale University, PhD Field of Study: Statistics
  • Yale University, MA Field of Study: Statistics
  • University of Bucharest, MS Field of Study: Statistics
  • University of Bucharest, BS Field of Study: Mathematics

Websites

Classes Taught

  • SPHBS849
  • SPHBS853
  • SPHBS854
  • SPHBS980

Publications

  • Published on 6/24/2024

    Venermo MA, Farber A, Schanzer A, Menard MT, Rosenfield K, Dosluoglu H, Goodney PP, Abou-Zamzam AM, Motaganahalli R, Doros G, Creager MA. Reduction of Major Amputations after Surgery Versus Endovascular Intervention: The BEST-CLI Randomised Trial. Eur J Vasc Endovasc Surg. 2024 Jun 24. PMID: 38925339.

     Read At: PubMed
  • Published on 6/20/2024

    Giles KA, Farber A, Menard MT, Conte MS, Nolan BW, Siracuse JJ, Strong M, Doros G, Venermo M, Azene E, Rosenfield K, Powell RJ. Surgery or Endovascular Therapy for Patients with Chronic Limb-threatening Ischemia Requiring Infrapopliteal Interventions. J Vasc Surg. 2024 Jun 20. PMID: 38908805.

     Read At: PubMed
  • Published on 4/16/2024

    Siracuse JJ, Menard MT, Rosenfield K, Conte MS, Powell R, Hamburg N, Doros G, Strong MB, Farber A. Characterization of cardiovascular serious adverse events after bypass or endovascular revascularization for limb-threatening ischemia in the BEST-CLI trial. J Vasc Surg. 2024 Apr 16. PMID: 38626847.

     Read At: PubMed
  • Published on 4/4/2024

    Cheng TW, Doros G, Jones DW, Vazirani A, Malikova MA. Evaluation of Computerized Tomography Utilization in Comparison to Digital Subtraction Angiography in Patients with Peripheral Arterial Disease. Ann Vasc Surg. 2024 Apr 04. PMID: 38582215.

     Read At: PubMed
  • Published on 2/17/2024

    Conte MS, Azene E, Doros G, Gasper WJ, Hamza T, Kashyap VS, Guzman R, Mena-Hurtado C, Menard MT, Rosenfield K, Rowe VL, Strong M, Farber A. Secondary interventions following open vs endovascular revascularization for chronic limb threatening ischemia in the BEST-CLI trial. J Vasc Surg. 2024 Jun; 79(6):1428-1437.e4. PMID: 38368997.

     Read At: PubMed
  • Published on 2/2/2024

    Misfeld M, Sandner S, Caliskan E, Böning A, Aramendi J, Salzberg SP, Choi YH, Perrault LP, Tekin I, Cuerpo GP, Lopez-Menendez J, Weltert LP, Adsuar-Gomez A, Thielmann M, Serraino GF, Doros G, Borger MA, Emmert MY. Outcomes after surgical revascularization in diabetic patients. Interdiscip Cardiovasc Thorac Surg. 2024 Feb 02; 38(2). PMID: 38218725.

     Read At: PubMed
  • Published on 12/11/2023

    Lau KHV, Prokaeva T, Zheng L, Doros G, Kaku MC, Spencer B, Berk J, Sanchorawala V. Neurofilament light chain kinetics as a biomarker for polyneuropathy in V122I hereditary transthyretin amyloidosis. Amyloid. 2024 Jun; 31(2):150-152. PMID: 38073425.

     Read At: PubMed
  • Published on 12/5/2023

    Farber A, Siracuse JJ, Giles K, Jones DW, Laskowski IA, Powell RJ, Rosenfield K, Strong MB, White CJ, Doros G, Menard MT. Investigator attitudes on equipoise and practice patterns in the BEST-CLI trial. J Vasc Surg. 2024 Apr; 79(4):865-874. PMID: 38056700.

     Read At: PubMed
  • Published on 8/20/2023

    Sarosiek S, Lee MH, Doros G, Edwards CV, Quillen K, Brauneis D, Shelton AC, Sanchorawala V, Sloan JM. Safety and Efficacy of Propylene Glycol-Free Melphalan in Patients with AL Amyloidosis Undergoing Autologous Stem Cell Transplantation: Results of a Phase II Study. Transplant Cell Ther. 2023 Nov; 29(11):695.e1-695.e7. PMID: 37607644.

     Read At: PubMed
  • Published on 8/3/2023

    Buckler AJ, Doros G, Kinninger A, Lakshmanan S, Le VT, Libby P, May HT, Muhlestein JB, Nelson JR, Nicolaou A, Roy SK, Shaikh K, Shekar C, Tayek JA, Zheng L, Bhatt DL, Budoff MJ. Quantitative imaging biomarkers of coronary plaque morphology: insights from EVAPORATE. Front Cardiovasc Med. 2023; 10:1204071. PMID: 37600044.

     Read At: PubMed

View 338 more publications:View Full Profile at BUMC

News & In the Media

View all profiles